Superior vena cava syndrome. Rapid histologic diagnosis by ultrasound-guided transthoracic needle aspiration biopsy.

abstract：:Disordered breathing during sleep is associated with acute, unfavorable effects on cardiovascular physiology, but few studies have examined its postulated association with cardiovascular disease (CVD). We examined the cross-sectional association between sleep- disordered breathing and self-reported CVD in 6,424 free-l...

journal_title：American journal of respiratory and critical care medicine

authors： Shahar E,Whitney CW,Redline S,Lee ET,Newman AB,Nieto FJ,O'Connor GT,Boland LL,Schwartz JE,Samet JM

更新日期：2001-01-01 00:00:00

abstract：RATIONALE:Breathing supplemental oxygen reduces breathlessness during exercise in patients with chronic obstructive pulmonary disease (COPD). Replacing nitrogen with helium reduces expiratory flow resistance and may improve lung emptying. Combining these treatments should be independently effective. OBJECTIVES:Study t...

journal_title：American journal of respiratory and critical care medicine

authors： Laude EA,Duffy NC,Baveystock C,Dougill B,Campbell MJ,Lawson R,Jones PW,Calverley PM

更新日期：2006-04-15 00:00:00

abstract：:To determine the relative contribution of ectopic calcitonin (CT) production versus nonectopic secretion of CT in patients with small cell lung cancer (SCLC), serum and urine immunoreactive CT (iCT) levels of 86 different subjects were measured by radioimmunoassay (RIA) using two polyclonal antisera (Ab3b and Ab4). Th...

journal_title：American journal of respiratory and critical care medicine

authors： Kelley MJ,Becker KL,Rushin JM,Venzon D,Phelps R,Ihde DC,Bliss DP Jr,Melby K,Snider RH,Johnson BE

更新日期：1994-01-01 00:00:00

abstract：:Many patients who develop incapacitating illness have not expressed clear treatment preferences. Therefore, surrogate decision makers are asked to make judgments about what treatment pathway is most consistent with the patient's values. Surrogates often struggle with such decisions. The difficulty arises because answe...

journal_title：American journal of respiratory and critical care medicine

authors： Scheunemann LP,Arnold RM,White DB

更新日期：2012-09-15 00:00:00

abstract：RATIONALE:Vitamin D has been shown to be involved in the host immune response toward Mycobacterium tuberculosis. OBJECTIVES:To test whether vitamin D supplementation of patients with tuberculosis (TB) improved clinical outcome and reduced mortality. METHODS:We conducted a randomized, double-blind, placebo-controlled ...

journal_title：American journal of respiratory and critical care medicine

authors： Wejse C,Gomes VF,Rabna P,Gustafson P,Aaby P,Lisse IM,Andersen PL,Glerup H,Sodemann M

更新日期：2009-05-01 00:00:00

abstract：:Reexpansion of collapsed lung creates intrapulmonary shear forces. In an earlier study we showed that application of a negative end-expiratory airway pressure (NEEP) to normal rabbit lungs in vivo produced tidal collapse and reexpansion with transient changes in compliance and gas exchange but no histologic damage. In...

journal_title：American journal of respiratory and critical care medicine

authors： Taskar V,John J,Evander E,Robertson B,Jonson B

更新日期：1997-01-01 00:00:00

abstract：:Rapid and selective recruitment of neutrophils into the airspace in response to LPS facilitates the clearance of bacterial pathogens. However, neutrophil infiltration can also participate in the development and progression of environmental airway disease. Previous data have revealed that Toll-like receptor 4 (tlr4) is...

journal_title：American journal of respiratory and critical care medicine

authors： Hollingsworth JW,Chen BJ,Brass DM,Berman K,Gunn MD,Cook DN,Schwartz DA

更新日期：2005-04-15 00:00:00

abstract：RATIONALE:Exposure to combustion-derived air pollution is associated with an early (1-2 h) and sustained (24 h) rise in cardiovascular morbidity and mortality. We have previously demonstrated that inhalation of diesel exhaust causes an immediate (within 2 h) impairment of vascular and endothelial function in humans. O...

journal_title：American journal of respiratory and critical care medicine

authors： Törnqvist H,Mills NL,Gonzalez M,Miller MR,Robinson SD,Megson IL,Macnee W,Donaldson K,Söderberg S,Newby DE,Sandström T,Blomberg A

更新日期：2007-08-15 00:00:00

abstract：:Airway inflammation is involved in the pathogenesis of bronchial asthma. Intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen-1 alpha (LFA-1 alpha) and has been shown to be required for leukocyte migration into inflamed area. The purpose of this report was to investigate th...

journal_title：American journal of respiratory and critical care medicine

authors： Nagase T,Fukuchi Y,Matsuse T,Sudo E,Matsui H,Orimo H

更新日期：1995-04-01 00:00:00

abstract：RATIONALE:Epidemiologic studies have shown that, in atopic children, wheezing is more likely to persist into adulthood, eventually becoming asthma, whereas it appears to resolve by adolescence in nonatopic children. OBJECTIVES:To investigate whether among children with multitrigger wheeze responsive to bronchodilators...

journal_title：American journal of respiratory and critical care medicine

authors： Turato G,Barbato A,Baraldo S,Zanin ME,Bazzan E,Lokar-Oliani K,Calabrese F,Panizzolo C,Snijders D,Maestrelli P,Zuin R,Fabbri LM,Saetta M

更新日期：2008-09-01 00:00:00

abstract：:The involvement of platelet-activating factor (PAF) in bronchial hyperresponsiveness (BHR) in bronchial asthma has been controversial. To determine whether PAF is involved in BHR in humans, we carried out a randomized, double-blind, placebo-controlled, two-phase cross-over study on the effects of Y-24180, a potent, sp...

journal_title：American journal of respiratory and critical care medicine

authors： Hozawa S,Haruta Y,Ishioka S,Yamakido M

更新日期：1995-10-01 00:00:00

abstract：:DNA fingerprinting of Mycobacterium tuberculosis is used to study the epidemiology of tuberculosis, but the specificity of the widely used IS6110 technique has not been validated. Isolates from Denver, Colorado from December 1988 through June 1994 were fingerprinted with the IS6110 technique. Available records were re...

journal_title：American journal of respiratory and critical care medicine

authors： Burman WJ,Reves RR,Hawkes AP,Rietmeijer CA,Yang Z,el-Hajj H,Bates JH,Cave MD

更新日期：1997-03-01 00:00:00

abstract：:The aim of the study was to investigate the effect of addition of montelukast to inhaled fluticasone propionate (FP) therapy, compared with FP therapy alone (100 microg twice a day) on airway immunopathology in individuals with mild asthma. Twenty-eight subjects received FP (100 microg twice a day) or FP (100 microg t...

journal_title：American journal of respiratory and critical care medicine

authors： O'Sullivan S,Akveld M,Burke CM,Poulter LW

更新日期：2003-03-01 00:00:00

abstract：RATIONALE:Pseudomonas aeruginosa is one of the leading causes of gram-negative ventilator-associated pneumonia (VAP) associated with a mortality rate of 34 to 68%. Recent evidence suggests that P. aeruginosa in patients with VAP may persist in the alveolar space despite adequate antimicrobial therapy. We hypothesized t...

journal_title：American journal of respiratory and critical care medicine

authors： El Solh AA,Akinnusi ME,Wiener-Kronish JP,Lynch SV,Pineda LA,Szarpa K

更新日期：2008-09-01 00:00:00

abstract：:The safety of sputum induction and the reproducibility of measurements in induced sputum in multicenter studies is unknown. We examined the safety of sputum induction in a two-visit, six-center study in 79 subjects with moderate to severe asthma (mean +/- SD FEV(1) 71 +/- 12% predicted, 67% taking inhaled corticostero...

journal_title：American journal of respiratory and critical care medicine

authors： Fahy JV,Boushey HA,Lazarus SC,Mauger EA,Cherniack RM,Chinchilli VM,Craig TJ,Drazen JM,Ford JG,Fish JE,Israel E,Kraft M,Lemanske RF,Martin RJ,McLean D,Peters SP,Sorkness C,Szefler SJ,NHLBI Asthma Clinical Research Netw

更新日期：2001-05-01 00:00:00

abstract：:The role of nutritional status in the prognosis of subjects with severe chronic obstructive pulmonary disease was studied in a cohort of Canadian men and women followed for 3 to 5 yr. A total of 348 subjects who were recruited for a study of negative pressure ventilation were evaluated for lung function and body weigh...

journal_title：American journal of respiratory and critical care medicine

authors： Gray-Donald K,Gibbons L,Shapiro SH,Macklem PT,Martin JG

更新日期：1996-03-01 00:00:00

abstract：:There is intriguing evidence suggesting pathophysiologic relationships among dyspnea, hyperventilation, and panic anxiety. The symptoms of panic attacks and pulmonary disease overlap, so that panic anxiety can reflect underlying cardiopulmonary disease and dyspnea can reflect an underlying anxiety disorder. The pathog...

journal_title：American journal of respiratory and critical care medicine

authors： Smoller JW,Pollack MH,Otto MW,Rosenbaum JF,Kradin RL

更新日期：1996-07-01 00:00:00

abstract：RATIONALE:The serial computed tomography findings and prognosis of the acute exacerbation of idiopathic pulmonary fibrosis (IPF) are not yet well defined in a larger number of cases. OBJECTIVES:To evaluate the parenchymal abnormalities and prognosis using high-resolution computed tomography (HRCT) in acute exacerbatio...

journal_title：American journal of respiratory and critical care medicine

authors： Akira M,Kozuka T,Yamamoto S,Sakatani M

更新日期：2008-08-15 00:00:00

abstract：RATIONALE:Neutrophils are key players in chronic obstructive pulmonary disease (COPD), and increased numbers of neutrophils are present in sputum and lung tissue of patients with COPD. Interestingly, immunoglobulin free light chains (IgLC) are able to prolong the life of neutrophils; therefore, IgLC may contribute to t...

journal_title：American journal of respiratory and critical care medicine

authors： Braber S,Thio M,Blokhuis BR,Henricks PA,Koelink PJ,Groot Kormelink T,Bezemer GF,Kerstjens HA,Postma DS,Garssen J,Kraneveld AD,Redegeld FA,Folkerts G

更新日期：2012-04-15 00:00:00

abstract：:The potential role of nitric oxide synthase-2 (NOS2) in acute lung injury (ALI) has gained increasing attention. This study evaluates the effects of hypoxia, an important feature of ALI, on NOS2 expression in a rat model of ALI caused by exposure to hypoxia and LPS. Exposure to hypoxia alone had no effect on the expre...

journal_title：American journal of respiratory and critical care medicine

authors： Agorreta J,Garayoa M,Montuenga LM,Zulueta JJ

更新日期：2003-08-01 00:00:00

abstract：:Despite several codes of research ethics, the issuance of comprehensive rules regarding informed consent by governmental agencies, and numerous writings on the subject of informed consent, many commentators still question the quality of the informed consent process in clinical research. A major concern is that investi...

journal_title：American journal of respiratory and critical care medicine

authors： Silverman HJ

更新日期：1996-09-01 00:00:00

abstract：:Rationale: Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological functions. Their role in pulmonary arterial hypertension (PAH) remains to be explored.Objectives: To elucidate the role of TYKRIL (tyrosine kinase receptor-inducing lncRNA) as a regulator of p53/ PDGFRβ (platelet-derive...

journal_title：American journal of respiratory and critical care medicine

authors： Zehendner CM,Valasarajan C,Werner A,Boeckel JN,Bischoff FC,John D,Weirick T,Glaser SF,Rossbach O,Jaé N,Demolli S,Khassafi F,Yuan K,de Jesus Perez VA,Michalik KM,Chen W,Seeger W,Guenther A,Wasnick RM,Uchida S,Zeihe

更新日期：2020-11-15 00:00:00

abstract：:The present prospective study was designed to determine the prevalence of pleural effusion at approximately 28 days after cardiac surgery and their subsequent course. This consecutive case study included 389 patients; 312 had only coronary artery bypass graft surgery (CABG) surgery, 37 had both valve and CABG surgery,...

journal_title：American journal of respiratory and critical care medicine

authors： Light RW,Rogers JT,Moyers JP,Lee YC,Rodriguez RM,Alford WC Jr,Ball SK,Burrus GR,Coltharp WH,Glassford DM Jr,Hoff SJ,Lea JW 4th,Nesbitt JC,Petracek MR,Starkey TD,Stoney WS,Tedder M

更新日期：2002-12-15 00:00:00

abstract：:A higher exposure to endotoxin was hypothesized to contribute to lower prevalence of allergic sensitization and hay fever in children growing up on a farm. We studied the association between house dust endotoxin and allergic sensitization. We randomly selected 740 children, aged between 5 and 10 years, from a group of...

journal_title：American journal of respiratory and critical care medicine

authors： Gehring U,Bischof W,Fahlbusch B,Wichmann HE,Heinrich J

更新日期：2002-10-01 00:00:00

abstract：:The effect of patient education on steroid inhaler compliance and rescue medication utilization in patients with asthma or chronic obstructive pulmonary disease (COPD) has not been previously investigated in a single study. We randomized 78 asthmatics and 62 patients with COPD after ordinary outpatient management. Int...

journal_title：American journal of respiratory and critical care medicine

authors： Gallefoss F,Bakke PS

更新日期：1999-12-01 00:00:00

abstract：:Many patients with acute asthma do not respond adequately to currently accepted therapy, including oxygen, beta-agonists, and corticosteroids. Leukotriene receptor antagonists such as montelukast have demonstrated efficacy in chronic asthma, but their efficacy in acute asthma is unknown. In this randomized, double-bli...

journal_title：American journal of respiratory and critical care medicine

authors： Camargo CA Jr,Smithline HA,Malice MP,Green SA,Reiss TF

更新日期：2003-02-15 00:00:00

abstract：:There is a subgroup of cigarette smokers who are more susceptible than others to the deleterious effects of cigarette smoke and to chronic airflow obstruction. The study of histopathologic and physiologic differences between these "susceptible" smokers and "resistant" smokers, who do not develop clinically significant...

journal_title：American journal of respiratory and critical care medicine

authors： Aguayo SM

更新日期：1994-06-01 00:00:00

abstract：:Oral mandibular advancement devices are becoming an increasingly important treatment alternative for obstructive sleep apnea (OSA). The first aim of the study was to determine whether a new oral elastic mandibular advancement device (EMA) prevents pharyngeal airway closure during sleep in patients with OSA. The second...

journal_title：American journal of respiratory and critical care medicine

authors： Henke KG,Frantz DE,Kuna ST

更新日期：2000-02-01 00:00:00

abstract：:At the time of diagnosis, many sarcoidosis patients have no clinical indication for corticosteroid therapy, and prognostic parameters predicting deterioration are missing. In the present study, we investigated parameters derived from bronchoalveolar lavage (BAL) and serum in 77 patients with recently diagnosed sarcoid...

journal_title：American journal of respiratory and critical care medicine

authors： Ziegenhagen MW,Benner UK,Zissel G,Zabel P,Schlaak M,Müller-Quernheim J

更新日期：1997-11-01 00:00:00

abstract：RATIONALE:Chronic exposure to indoor nitrogen dioxide (NO2) is a public health concern. Over half of U.S. households have a source of NO2, and experimental data suggest potential for adverse respiratory effects. OBJECTIVE:To examine associations of indoor NO2 exposure with respiratory symptoms among children with asth...

journal_title：American journal of respiratory and critical care medicine

authors： Belanger K,Gent JF,Triche EW,Bracken MB,Leaderer BP

更新日期：2006-02-01 00:00:00