Abstract:
STUDY OBJECTIVE:To review the incidence of leukaemia and non-Hodgkin's lymphoma in children and young adults in the area less than 25 km from the Dounreay nuclear installation and the remainder of the Kirkwall postcode area in the full time period for which data are now available (1968-91), and to determine whether the excess incidence reported in the period up to 1984 has continued in subsequent years. DESIGN:Geographical incidence study. SETTING:The Kirkwall postcode area of Scotland. SUBJECTS:Children and young adults resident in the area in the period 1968-91. MAIN RESULTS:Observed numbers of cases of leukaemia and non-Hodgkin's lymphoma and observed to expected ratios with expected numbers based on Scottish national rates were determined. In 1968-91, 12 cases were observed compared with 5.2 expected in the zone < 25 km from the Dounreay plant (p = 0.007). In the latest period, 1985-91, which has not previously been examined, four cases were observed compared with 1.4 expected (p = 0.059). CONCLUSION:The observation of an excess of borderline statistical significance in 1985-91 following the substantial excess incidence which occurred in the early 1980s suggests that the incidence of leukaemia and non-Hodgkin's lymphoma in this area should continue to be a matter of concern. The phenomenon of high incidences of childhood and young adult leukaemia and lymphoma near some nuclear installations in isolated areas is yet to be explained, but certain aspects of the data examined in the present report are consistent with the hypothesis of an infectious aetiology for leukaemia in very young children.
journal_name
J Epidemiol Community Healthjournal_title
Journal of epidemiology and community healthauthors
Black RJ,Sharp L,Harkness EF,McKinney PAdoi
10.1136/jech.48.3.232subject
Has Abstractpub_date
1994-06-01 00:00:00pages
232-6issue
3eissn
0143-005Xissn
1470-2738journal_volume
48pub_type
杂志文章abstract:BACKGROUND:Reliable data on clinical biomarkers are necessary in order to assess the health risks of populations and especially in assessing long-term trends related to disease incidence. METHODS:Ten European laboratories participated in a two-phase quality control exercise of total cholesterol (TC) and high-density l...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2018-210763
更新日期:2018-07-01 00:00:00
abstract:STUDY OBJECTIVE:To examine the geographical variation in self perceived morbidity in the south west of England, and assess the associations with rurality and social deprivation. DESIGN:A geographically based cross sectional study using 1991 census data on premature Limiting Long Term Illness (LLTI). The urban-rural an...
journal_title:Journal of epidemiology and community health
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abstract:OBJECTIVE:To examine the association of self-reported health (SRH) with the apolipoprotein E (APOE) gene, life stress, and sociobehavioural factors in adults aged 55 and over. DESIGN:Secondary analysis of data from the Social Environment and Biomarkers of Aging Study (SEBAS) in Taiwan in 2000, comprising 1023 individu...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究
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abstract:BACKGROUND:Promoting walking and cycling as a part of everyday activity is seen as a strategy for tackling obesity and chronic disease. Policy needs to be based on evidence about people's views of walking and cycling as well as effects of interventions. METHODS:Studies of the views of children, young people and parent...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
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更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES:(1) To assess the association between birth weight and coronary heart disease (CHD) risk in a cohort of post-menopausal women, (2) to determine the combined effects of birth weight and adult body mass index on CHD, (3) to assess the role of insulin resistance as a mediating factor in the associations. DESIG...
journal_title:Journal of epidemiology and community health
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更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:To empirically test the impact of dietary intake at several time points in childhood on children's school attainment and to investigate whether any differences in school attainment between children who ate packed lunches or school meals was due to who these children were, their pre-school dietary patterns, o...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2007.068213
更新日期:2008-08-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2004.027854
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Life expectancy at birth in Spain improved between 1972 and 1982, by 2.5 years for males and 3.2 years for females. This slowed considerably in the following decade, with increases of only 0.5 and 1.7 years respectively. OBJECTIVE:To determine the causes of death that have been responsible for the failure b...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.51.5.510
更新日期:1997-10-01 00:00:00
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journal_title:Journal of epidemiology and community health
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更新日期:1980-12-01 00:00:00
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更新日期:1994-08-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether methadone maintenance treatment (MMT) is effective in reducing the levels of HIV risk-taking behaviour (borrowing and lending of injection equipment, irregular condom use) among injecting drug users (IDUs), and to identify independent predictors of the borrowing of used syringes. D...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.50.5.534
更新日期:1996-10-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.35.2.146
更新日期:1981-06-01 00:00:00
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journal_title:Journal of epidemiology and community health
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更新日期:2009-07-01 00:00:00
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更新日期:2007-09-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-11-06 00:00:00
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doi:10.1136/jech.56.11.868
更新日期:2002-11-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1997-04-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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更新日期:1997-12-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.45.1.73
更新日期:1991-03-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.42.2.187
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND:Earlier investigations have shown mortality effects of community socio-economic resources. However, the sex differences have not been clear, and the estimates may well have been biased because of inadequate control for community factors affecting both the socio-economic resources and mortality. The objective...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.081034
更新日期:2010-12-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2005.043851
更新日期:2006-08-01 00:00:00
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journal_title:Journal of epidemiology and community health
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更新日期:2006-09-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2002-09-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2018-210977
更新日期:2019-03-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
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更新日期:2017-07-25 00:00:00