Abstract：
:There is widespread interest in obtaining genetic samples from human populations worldwide for various studies of human genetic diversity. Many samples exist today only in the form of small, rare, irreplaceable, or archival samples, such as material from ancient bone, hair bulbs, or remnants of samples collected in the field decades ago for the purpose of protein and blood type analysis. Here, we describe the application of an approach to amplify DNA, which we call adapter attachment and amplification (AAA). This approach is useful for amplifying the genome in a reasonably representative way from small amounts of starting material using standard PCR-based methods. We apply a version of these methods to DNA extracted from washed red blood cells collected in the 1960s and 1970s in the Amazon basin. AAA and similar approaches may make the analysis of archival samples possible without exhausting that irreplaceable material and may lead to greatly improved efficiency in collecting and using new anthropological genetic samples.
journal_name
Hum Bioljournal_title
Human biologyauthors
Weiss KM,Buchanan AV,Daniel C,Stoneking Msubject
Has Abstractpub_date
1994-10-01 00:00:00pages
789-804issue
5eissn
0018-7143issn
1534-6617journal_volume
66pub_type
杂志文章相关文献
HUMAN BIOLOGY文献大全abstract：:Although anthropometric information on South American Indian populations has been collected for many years, remarkably little is known about age-related changes in their body size in adulthood. The lack of baseline information on the normal pattern of aging among Amerindian adults hinders investigations into the healt...
journal_title：Human biology
pub_type： 杂志文章
doi：10.1353/hub.2003.0031
更新日期：2003-04-01 00:00:00
abstract：:We describe the gene frequency distributions for 29 different blood group, serum, and erythrocytic proteins for three Mennonite communities from Kansas and Nebraska and compare their gene frequencies with those of Amish, Hutterite, and Mennonite populations using the topological method of Harpending and Jenkins (1973)...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：:We have investigated the clinical, hematological, and molecular genetic characteristics of sickle cell anemia patients from 6 populations of Andhra Pradesh, South India. Of 72 sickle cell chromosomes (HBB*S) 60 belong to characteristic Arab-Indian haplotypes, 6 to variant Arab-Indian haplotypes, 1 to a Bantu haplotype...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:The Norse and Celtic contributions to the founding population of Iceland have been estimated previously on a pan-Icelandic basis using gene frequency data for the entire island. Accounts of the settlement of Iceland, however, suggest that different regions received different proportions of Norse and Celtic settlers, i...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：:A central problem in research on twins is the estimation of the rates of monozygotic and dizygotic twin maternities. The estimation usually follows Weinberg's differential rule. According to this rule, the rate of dizygotic twinning is twice the rate of twin maternities in which the twins are of opposite sex. The mono...
journal_title：Human biology
pub_type： 杂志文章,评审
doi：10.1353/hub.2006.0044
更新日期：2006-06-01 00:00:00
abstract：:The fertility pattern, in terms of birth intervals, in a rural population not practicing contraception belonging to La Alta Alpujarra Oriental (southeast Spain) is analyzed. During the first half of the 20th century, this population experienced a considerable degree of geographical and cultural isolation. Because of t...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：2000-10-01 00:00:00
abstract：:Colon cancer is known to be heritable in humans, but the opportunity to investigate the genetic epidemiology of cancer in nonhuman primates has been limited by the size of available populations. The cotton-top tamarin (Saguinus oedipus) colony at the Oak Ridge Associated Universities (ORAU) Marmoset Research Center is...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:Alleles of the hypervariable human locus D17S5 were amplified by polymerase chain reaction (PCR) and categorized by length. Unlike other surveys of this locus, the products of amplification were authenticated by Southern analysis using an oligomeric probe directed to part of the 70-base-pair (bp) variable number of ta...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Growth is a complex process composed of distinct phases over the course of childhood. Although the pubertal growth spurt has received the most attention from auxologists and pediatricians, the midchildhood growth spurt has been less well studied. The midchildhood growth spurt refers to a relatively small increase in g...
journal_title：Human biology
pub_type： 杂志文章
doi：10.3378/1534-6617-80.6.623
更新日期：2008-12-01 00:00:00
abstract：:Anthropoid phylogeny has been characterized by dramatic increases in relative brain size. Given the importance of genetic mechanisms in evolution, quantitative genetic analyses of the biological concomitants of relative brain size variation should greatly augment our understanding of this phylogenetic phenomenon. In h...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:To what extent can ethnic factors contribute to the prevalence of type 2 diabetes and impaired glucose tolerance (IGT) in an urban Brazilian population? Conversely, how can environmental factors such as diet change these prevalences in a given ethnic group, in this case Brazilian Indians? To answer these questions est...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：2002-08-01 00:00:00
abstract：:Relatives may tend to die of the same cause. A model is proposed specifying the degree of this association, simultaneously allowing for misclassification of cause of death. These mistakes usually degrade any existing correlation structure, the effects being marked when error rates reach between 20% to 30%. It is then ...
journal_title：Human biology
pub_type： 杂志文章
doi：10.1353/hub.2002.0013
更新日期：2002-02-01 00:00:00
abstract：:Paleodemographic studies have seldom been attempted in sub-Saharan Africa. The Mapungubwe complex of sites in northern Transvaal (A.D. 970-1200) has yielded enough skeletal material to warrant such an investigation. The skeletal collection consists of 109 individuals (97 from K2 and 12 from Mapungubwe itself). Because...
journal_title：Human biology
pub_type： 历史文章,杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:Involvement of genetic factors in determining bone mineral density (BMD) is doubtless. However, the exact nature of the genes governing BMD variation and sources for genetic determination of BMD of different parts of bone (compact and cancellous) have not been completely studied. The results of the complex segregation...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Recent research has questioned whether the European Black Death of 1347-1351 could possibly have been caused by the bubonic plague bacillus Yersinia pestis, as has been assumed for over a century. Central to the arguments both for and against involvement of Y. pestis has been a comparison of the temporal dynamics obse...
journal_title：Human biology
pub_type： 传,历史文章,杂志文章
doi：10.1353/hub.2003.0067
更新日期：2003-08-01 00:00:00
abstract：:The primary purpose of this research is to collate, compare, and discuss the presently available data for head and face dimensions among Korean and Japanese ethnic groups. Classification of Korean male and female head and face types is simpler than classification of Japanese subjects. Male groups have more statistical...
journal_title：Human biology
pub_type： 杂志文章
doi：10.3378/1534-6617-80.3.313
更新日期：2008-06-01 00:00:00
abstract：:Large-scale genotyping and next-generation sequencing techniques have allowed great advances in the field of molecular genetics. Numerous common variants of low impact have been associated with many complex human traits and diseases, such as bipolar disorder and schizophrenia. Although they may exert a greater impact ...
journal_title：Human biology
pub_type： 杂志文章
doi：10.13110/humanbiology.88.2.0109
更新日期：2016-04-01 00:00:00
abstract：:There has been a lack of agreement on the variation in and the correlates of menstrual cycle length in the literature. A total of 2566 women from rural and urban areas in one district of Tamil Nadu in southern India were studied prospectively to identify correlates of menstrual cycle length. Rural women had higher odd...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：:"Pygmy populations" are recognized in several places over the world, especially in Western Africa and in Southeast Asia (Philippine "negritos," for instance). Broadly defined as "small-bodied Homo sapiens" (compared with neighboring populations), their origins and the nature of the processes involved in the maintenanc...
journal_title：Human biology
pub_type： 杂志文章
doi：10.3378/027.085.0303
更新日期：2013-02-01 00:00:00
abstract：:We carried out an exploratory historical biology study using temporally distinguished groups of predynastic-Early Dynastic male crania from the region of Upper Egypt. The objectives were, first, to determine the overall pattern of phenetic affinity between temporally sequential series and in relation to the earliest s...
journal_title：Human biology
pub_type： 历史文章,杂志文章
doi：10.3378/1534-6617(2008)80[141:TVIPAO]2.0.CO;2
更新日期：2008-04-01 00:00:00
abstract：:Although much attention has been given to statistical genetic methods for the initial localization and fine mapping of quantitative trait loci (QTLs), little methodological work has been done to date on the problem of statistically identifying the most likely functional polymorphisms using sequence data. In this paper...
journal_title：Human biology
pub_type： 杂志文章
doi：10.1353/hub.2006.0003
更新日期：2005-10-01 00:00:00
abstract：:Eleven short tandem repeat loci (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, TH01, and TPOX) were investigated in 232 individuals from 6 Amazonian native tribes (Tiriyó, Waiãpi, Zoé, Urubu-Kaapor, Awa-Guajá, and Parakanã). We added the new data to a database that included five previousl...
journal_title：Human biology
pub_type： 杂志文章
doi：10.3378/027.081.0106
更新日期：2009-02-01 00:00:00
abstract：:A tribal aboriginal community, the Mowanjum, from the Kimberley region in Western Australia has been screened to determine the extent of genetic variation in the products of genes coding for apolipoproteins, which are intimately involved in lipid metabolism. Of the seven systems tested, APOE and APOH revealed common s...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:The frequency of a polymorphic mitochondrial DNA insertion into the nuclear genome was determined for 870 individuals from a geographically diverse set of 20 populations. The mtDNA insertion frequency varies significantly among populations, having a large GST value (0.178) and high heterozygosity values within populat...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Mitochondrial DNA haplotype studies have been useful in unraveling the origins of Native Americans. Such studies are based on restriction site and intergenic deletion/insertion polymorphisms, which define four main haplotype groups common to Asian and American populations. Several studies have characterized these line...
journal_title：Human biology
pub_type： 杂志文章
doi：10.1353/hub.2002.0022
更新日期：2002-04-01 00:00:00
abstract：:The use of ancient DNA techniques in human studies has been hampered by problems of contamination with modern human DNA. The main problem has been that the object of study belongs to the same species as the observer, and the complete elimination of the contamination risk is seemingly unlikely. Contamination has even b...
journal_title：Human biology
pub_type： 历史文章,杂志文章
doi：10.1353/hub.2001.0069
更新日期：2001-10-01 00:00:00
abstract：:Genetic polymorphisms of the complement components (five loci: C2, C3, C4A, C4B, and BF) have been investigated in the Telugu-speaking Hindu population of Hyderabad, Andhra Pradesh, India, and the Bangali-speaking Muslim population of Dacca, Bangladesh. The available data are compared to understand the genetic variati...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:To determine the origin of sickle cell mutation in different ethnic groups living in southern Iran, we studied the haplotype background of the betaS and betaA genes in subjects from the provinces of Fars, Khuzestan, Bushehr, Hormozgan, and Kerman and from the islands of Khark and Qeshm. beta-globin gene cluster haplot...
journal_title：Human biology
pub_type： 杂志文章
doi：10.1353/hub.2007.0016
更新日期：2006-12-01 00:00:00
abstract：:The DNA profiles of two unrelated individuals can match (complete similarity) by chance alone. When the two individuals are related, the probability of a coincidental match is higher. Here, I deal with the probabilities of coincidental matches for both related and unrelated individuals. The derivation starts from firs...
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:GM and KM immunoglobulin (Ig) allotypes were tested in 118 autochthonous Basques from northern Navarre. The results are compared to those obtained for the same genetic markers in 6 other Basque subpopulations, 3 from Spain (Guipúzcoa, Vizcaya, and Alava) and 3 from France: Macaye, Saint-Jean Pied de Port, and Mauleon....
journal_title：Human biology
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
