Finding Rare, Disease-Associated Variants in Isolated Groups: Potential Advantages of Mennonite Populations.

abstract：:Dermatoglyphic traits have been used to assess population affinities and structure. Here, we describe the digital patterns of four Eskimo populations from Alaska: two Yupik-speaking villages from St. Lawrence Island and two Inupik groups presently residing on mainland Alaska. For a broader evolutionary perspective, th...

journal_title：Human biology

authors： Crawford MH,Duggirala R

更新日期：1992-10-01 00:00:00

abstract：:We summarize the results of a field and laboratory research program (1999-2006) in the Aleutian Islands on the origins of the inhabitants of the archipelago and the genetic structure of these populations. The Aleuts show closest genetic affinity to the contemporary Siberian Eskimos and Chukchi of Chukotka and differ s...

journal_title：Human biology

authors： Crawford MH,Rubicz RC,Zlojutro M

更新日期：2010-12-01 00:00:00

abstract：:We used 15 short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, D18S51, D5S818, and FGA) to genetically characterize 361 individuals from 11 indigenous populations (Amuzgo, Chinanteco, Chontal, Huave, Mazateco, Mixe, Mixteco, Triqui, Zapoteco de...

journal_title：Human biology

authors： Quinto-Cortés CD,Arriola LA,García-Hughes G,García-López R,Molina DP,Flores M,Palacios R,Piñero D

更新日期：2010-08-01 00:00:00

abstract：:It is generally accepted that the relationship between human genes and language is very complex and multifaceted. This has its roots in the “regular” complexity governing the interplay among genes and between genes and environment for most phenotypes, but with the added layer of supraontogenetic and supra-individual p...

journal_title：Human biology

authors： Dediu D

更新日期：2011-04-01 00:00:00

abstract：:The theoretical literature on human population dispersal processes at the large time and space scale is reviewed, including references to and discussions of relevant empirical data. The basic Fisher-KPP reaction-diffusion system is summarized for the single population situation, and developments relating to the Allee ...

journal_title：Human biology

authors： Steele J

更新日期：2009-04-01 00:00:00

abstract：:Models that examine genetic differences between populations alongside a genotype-phenotype map can provide insight about phenotypic variation among groups. We generalize a simple model of a completely heritable, additive, selectively neutral quantitative trait to examine the relationship between single-locus genetic d...

journal_title：Human biology

authors： Edge MD,Rosenberg NA

更新日期：2015-10-01 00:00:00

abstract：:When sampling locations are known, the association between genetic and geographic distances can be tested by spatial autocorrelation or regression methods. These tests give some clues to the possible shape of the genetic landscape. Nevertheless, correlation analyses fail when attempting to identify where genetic barri...

journal_title：Human biology

authors： Manni F,Guérard E,Heyer E

更新日期：2004-04-01 00:00:00

abstract：:Eleven short tandem repeat loci (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, TH01, and TPOX) were investigated in 232 individuals from 6 Amazonian native tribes (Tiriyó, Waiãpi, Zoé, Urubu-Kaapor, Awa-Guajá, and Parakanã). We added the new data to a database that included five previousl...

journal_title：Human biology

authors： Dos Santos SE,Ribeiro-Rodrigues EM,Ribeiro-Dos-Santos AK,Hutz MH,Tovo-Rodrigues L,Salzano FM,Callegari-Jacques SM

更新日期：2009-02-01 00:00:00

abstract：:The DNA profiles of two unrelated individuals can match (complete similarity) by chance alone. When the two individuals are related, the probability of a coincidental match is higher. Here, I deal with the probabilities of coincidental matches for both related and unrelated individuals. The derivation starts from firs...

journal_title：Human biology

authors： Li CC

更新日期：1996-04-01 00:00:00

abstract：:In one of the truly classic works in anthropological genetics, Frank Livingstone established the interrelationships between agriculture, mosquito ecology, malaria, and, consequently, the frequencies of sickle cell hemoglobin in West Africa. A major inference from Livingstone's study was the recency of malaria as a sel...

journal_title：Human biology

authors： Fix AG

更新日期：2003-08-01 00:00:00

abstract：:The primary purpose of this research is to collate, compare, and discuss the presently available data for head and face dimensions among Korean and Japanese ethnic groups. Classification of Korean male and female head and face types is simpler than classification of Japanese subjects. Male groups have more statistical...

journal_title：Human biology

authors： Lee HJ,Park SJ

更新日期：2008-06-01 00:00:00

abstract：:Human population characteristics at the genetic level are integral to both forensic biology and population genetics. This study evaluates biparental microsatellite markers in five Austronesian-speaking groups to characterize their intra- and interpopulation differences. Genetic diversity was analyzed using 15 short ta...

journal_title：Human biology

authors： Shepard EM,Chow RA,Suafo'a E,Addison D,Pérez-Miranda AM,Garcia-Bertrand RL,Herrera RJ

更新日期：2005-12-01 00:00:00

abstract：:We present the most comprehensive genetic characterization to date of five Fijian island populations: Viti Levu, Vanua Levu, Kadavu, the Lau Islands, and Rotuma, including nonrecombinant Y (NRY) chromosome and mitochondrial DNA (mtDNA) haplotypes and haplogroups. As a whole, Fijians are genetically intermediate betwee...

journal_title：Human biology

authors： Shipley GP,Taylor DA,N'Yeurt ADR,Tyagi A,Tiwari G,Redd AJ

更新日期：2016-07-01 00:00:00

abstract：:Three apolipoprotein B restriction fragment length polymorphism (RFLPs) (XbaI, MspI, and EcoRI) and the signal peptide insertion-deletion polymorphism were investigated using the polymerase chain reaction in 140 individuals from 5 Brazilian Indian tribes. All studied markers were polymorphic in this ethnic group. The ...

journal_title：Human biology

authors： Kaufman L,Vargas AF,Coimbra Júnior CE,Santos RV,Salzano FM,Hutz MH

更新日期：1999-02-01 00:00:00

abstract：:Hematocrit values are normally higher in natives living at high altitude than in natives living at sea level. Here, we have determined the hematocrit levels in relation to adrenal androgens in children living at altitudes of 150 m and 3400 m above sea level. The data demonstrate no association between serum adrenal an...

journal_title：Human biology

authors： Góñez C,Donayre M,Villena A,Gonzales GF

更新日期：1993-02-01 00:00:00

abstract：:Cross-cultural studies of sex-specific mortality indicate that, whereas males experience their greatest mortality in industrialized societies, females experience their greatest mortality in populations with low life expectancy. The higher mortality of females in low-life-expectancy communities has been interpreted as ...

journal_title：Human biology

authors： Madrigal L

更新日期：1992-04-01 00:00:00

abstract：:A recent workshop entitled "The Family Name as Socio-Cultural Feature and Genetic Metaphor: From Concepts to Methods" was held in Paris in December 2010, sponsored by the French National Centre for Scientific Research (CNRS) and by the journal Human Biology. This workshop was intended to foster a debate on questions r...

journal_title：Human biology

authors： Darlu P,Bloothooft G,Boattini A,Brouwer L,Brouwer M,Brunet G,Chareille P,Cheshire J,Coates R,Dräger K,Desjardins B,Hanks P,Longley P,Mandemakers K,Mateos P,Pettener D,Useli A,Manni F

更新日期：2012-04-01 00:00:00

abstract：:I describe the developmental, metric, morphologic, and pathologic features of deciduous dentition in a terminal Late Archaic (c. 3000 B.P.) Native American population in Ohio. Development of deciduous dentition in this Late Archaic population is stable with little sequence variation. The pattern of development (ldc, l...

journal_title：Human biology

authors： Sciulli PW

更新日期：1990-04-01 00:00:00

abstract：:Controversies resulting from genetic testing on skeletal remains of disputed stewardship raise important questions about obligations inherent on genetic researchers to assure ethical chain of custody. In this article, we analyze and evaluate several proposed positions on whether such research should be published. Foll...

journal_title：Human biology

authors： May T,Nakano-Okuno M

更新日期：2019-02-17 00:00:00

abstract：:Given the same reproductive span, more children with shorter interbirth intervals and less parental attention per child should not do as well. There should be intermediate optima in family sizes, but only two studies have demonstrated optima. The goal here is to determine whether the relationship between fitness and f...

journal_title：Human biology

authors： Stevenson JC,Everson PM,Grimes M

更新日期：2004-10-01 00:00:00

abstract：:It was predicted that at the state level early neonatal (0-6 days) mortality rates and rates for sudden infant death syndrome (SIDS) in the age range 7-364 days would be negatively correlated. Using published data for each of the 50 states and the District of Columbia over the 5-year period 1980-1984, the actual corre...

journal_title：Human biology

authors： Spiers PS

更新日期：1991-08-01 00:00:00

abstract：:We summarize several studies, from the last 10 years, of temporal changes and rural-urban differences in the risk factors of cardiovascular disease (CVD) in China to indicate the influences of economic modernization. Two national blood pressure surveys have shown that the prevalence of hypertension increased from 5.1%...

journal_title：Human biology

authors： Zhai S,McGarvey ST

更新日期：1992-12-01 00:00:00

abstract：:The amiloride-sensitive epithelial sodium channel is a highly selective sodium channel that constitutes the rate-limiting step of sodium reabsorption in distal nephrons. It consists of at least 3 subunits (alpha, beta, and gamma) of similar structure and plays an important role in sodium and fluid homeostasis. Defects...

journal_title：Human biology

authors： Xu X,Niu T,Chen C,Yang J,Fang Z,Xu X

更新日期：1999-10-01 00:00:00

abstract：:Relatives may tend to die of the same cause. A model is proposed specifying the degree of this association, simultaneously allowing for misclassification of cause of death. These mistakes usually degrade any existing correlation structure, the effects being marked when error rates reach between 20% to 30%. It is then ...

journal_title：Human biology

authors： Tallis GM

更新日期：2002-02-01 00:00:00

abstract：:In this paper I propose that evolutionary demography and associated theory from human behavioral ecology provide a strong basis for explaining the available evidence for the patterns observed in the first agricultural settlement of Europe in the 7th-5th millennium cal. BC, linking together a variety of what have previ...

journal_title：Human biology

authors： Shennan S

更新日期：2009-04-01 00:00:00

abstract：:There has been a lack of agreement on the variation in and the correlates of menstrual cycle length in the literature. A total of 2566 women from rural and urban areas in one district of Tamil Nadu in southern India were studied prospectively to identify correlates of menstrual cycle length. Rural women had higher odd...

journal_title：Human biology

authors： Jeyaseelan L,Rao PS

更新日期：1993-08-01 00:00:00

abstract：:Details of the population pyramid of living Herero and Mbanderu of Botswana suggest that infant and childhood mortality of males has been substantially greater than that of females. Direct tests from reproductive histories show that the hazard ratio is approximately 3 to 1 in favor of female survival in infancy and 2 ...

journal_title：Human biology

authors： Harpending HC,Pennington R

更新日期：1991-06-01 00:00:00

abstract：:A random sample of death records of adult males from the period 1967 to 1970 was chosen from the South Australian Registry of Births, Deaths, and Marriages. The natural parents of these individuals were identified by cross-referencing to birth certificates, and an extensive search was made of the death records for the...

journal_title：Human biology

authors： Tallis GM,Leppard P

更新日期：1997-12-01 00:00:00

abstract：:Mitochondrial DNA haplotype studies have been useful in unraveling the origins of Native Americans. Such studies are based on restriction site and intergenic deletion/insertion polymorphisms, which define four main haplotype groups common to Asian and American populations. Several studies have characterized these line...

journal_title：Human biology

authors： Keyeux G,Rodas C,Gelvez N,Carter D

更新日期：2002-04-01 00:00:00

abstract：:The two polymorphic alleles of esterase D (ESD), ESD*5 and ESD*7, are specific to Europeans and Asians, respectively. In this study the molecular basis was characterized: ESD*5, arising from ESD*1, has a G to A transition, resulting in Gly257(GGT) --> Asp(GAT); and ESD*7, originating from ESD*2, has an A to G transiti...

journal_title：Human biology

authors： Yuasa I,Umetsu K,Tsuchida S,Irizawa Y,Henke L,Henke J

更新日期：2004-06-01 00:00:00