Abstract:
:This paper reports the synthesis of the new compound 1-[2-acetoxy-3-(4-phenyl-1-piperazinyl)propyl]pyrrolidin-2-one (Ac-MG-1). Preliminary pharmacological assessment revealed that Ac-MG-1 possesses anti-arrhythmic activity and a local anesthetic effect. The crystal structure of Ac-MG-1 was determined by X-ray diffraction, and conformational analysis was performed both for Ac-MG-1 and for other derivatives of (arylpiperazinyl)propylpyrrolidin-2-one.
journal_name
Arch Pharm (Weinheim)journal_title
Archiv der Pharmazieauthors
Malawska B,Filipek B,Stadnicka K,Ciechanowicz-Rutkowska Mdoi
10.1002/ardp.19953280613subject
Has Abstractpub_date
1995-06-01 00:00:00pages
541-6issue
6eissn
0365-6233issn
1521-4184journal_volume
328pub_type
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