Organ transplantation and osteoporosis.

abstract：:The Achilles tendon is the strongest tendon in the human body. Because most Achilles tendon injuries take place in sports and there has been an common upsurge in sporting activities, the number and incidence of the Achilles tendon overuse injuries and complete ruptures have increased in the industrialized countries du...

journal_title：Current opinion in rheumatology

authors： Järvinen TA,Kannus P,Paavola M,Järvinen TL,Józsa L,Järvinen M

更新日期：2001-03-01 00:00:00

abstract：:Refinement of criteria for classifying childhood rheumatic diseases has contributed to earlier, more complete, and more precise diagnosis of children with spondyloarthropathies. Recent additions to the literature have contributed new international perspectives relating to the prevalence of juvenile spondyloarthropathi...

journal_title：Current opinion in rheumatology

authors： Rosenberg AM

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:Signal transduction pathways are the intracellular mechanism by which cells respond and adapt to environmental stress. Understanding the critical networks in diseases like rheumatoid arthritis can potentially identify novel therapeutic targets. RECENT FINDINGS:Dissecting the complex pathways involved in rheuma...

journal_title：Current opinion in rheumatology

authors： Sweeney SE,Firestein GS

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Diffuse idiopathic skeletal hyperostosis (DISH) or Forestier's disease is a common disorder among older adults. The diagnosis is based solely on radiographic abnormalities defined using the Resnick criteria. DISH is characterized by ossification of the anterior longitudinal ligament of the spine and v...

journal_title：Current opinion in rheumatology

authors： Sarzi-Puttini P,Atzeni F

更新日期：2004-05-01 00:00:00

abstract：:Estimates of the prevalence and incidence of knee osteoarthritis increase with age and are higher for women. Other differences in such estimates arise due to methodologic variables, including radiographic techniques. The risk for knee osteoarthritis increases with increasing body weight, long-term occupational joint s...

journal_title：Current opinion in rheumatology

authors： Slemenda CW

更新日期：1992-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article was to review the recent contributions to the scoring methods of PET in vasculitis as well as to its role in the diagnostic work-up. RECENT FINDINGS:Both visual and semiquantitative scoring methods can be used to interpret PET scans. PET has been shown to be both sensitive and...

journal_title：Current opinion in rheumatology

authors： Pipitone NAM,Versari A,Salvarani C

更新日期：2018-01-01 00:00:00

abstract：:The polymorphism of HLA-B27 alleles is located in the peptide-anchoring motif. In recent years, fundamental insights have been made into the molecular aspects of HLA-B27-restricted presentation. Subtle differences in peptide binding fine specificity are especially interesting for closely related HLA-B27 alleles that h...

journal_title：Current opinion in rheumatology

authors： López-Larrea C,Gonzalez-Roces S,Alvarez V

更新日期：1996-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Arthritogenic alphaviruses are globally distributed mosquito-borne RNA viruses causing epidemics of polyarthritis/arthralgia, with disease emerging or reemerging and increasingly being reported in travelers. This article summarizes the current knowledge of these diseases, focusing on recent developmen...

journal_title：Current opinion in rheumatology

authors： Suhrbier A,La Linn M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Autoimmune pancreatitis (AIP) is a peculiar type of pancreatitis with a presumed autoimmune etiology. AIP is frequently associated with stenosis of the bile duct in the form of IgG4-related sclerosing cholangitis. This article reviews recent advances in clinicopathological findings for AIP and IgG4-re...

journal_title：Current opinion in rheumatology

authors： Takuma K,Kamisawa T,Igarashi Y

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There are currently several available biologics for rheumatoid arthritis (RA) with similar efficacy in most trials. A major consideration therefore in choosing a biologic, continues to be safety concerns such as infection. Considerable advances have been made in the understanding of biologic safety on...

journal_title：Current opinion in rheumatology

authors： Jani M,Barton A,Hyrich K

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:IgG4-related disease (IgG4-RD) is a recently described fibroinflammatory condition that can affect nearly any organ. Our knowledge of this condition--its manifestations, diagnosis, pathogenesis and treatment--is expanding rapidly. RECENT FINDINGS:This review highlights the most recent developments in...

journal_title：Current opinion in rheumatology

authors： Wallace ZS,Stone JH

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Since their discovery over 15 years ago, intensive research has focused on the presence, phenotype and function of FOXP3(+) regulatory T cells (Treg) in autoimmune diseases such as rheumatoid arthritis (RA). The questions of whether Treg deficiencies underlie autoimmune pathology and whether or how Tr...

journal_title：Current opinion in rheumatology

authors： Mijnheer G,Prakken BJ,van Wijk F

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Systemic sclerosis, or scleroderma, is a systemic autoimmune disease manifest by vascular damage and fibrosis within the skin and visceral organs. Whereas scleroderma is a heterogenous disorder in terms of disease symptoms and clinical course, scleroderma-specific autoantibody profiles associate stron...

journal_title：Current opinion in rheumatology

authors： Harris ML,Rosen A

更新日期：2003-11-01 00:00:00

abstract：:Due to our increasing knowledge of mechanisms underlying pathogenic events in autoimmune rheumatic diseases, biologic agents have been further explored and tested in open and controlled clinical trials. Based on the results of placebo-controlled trials, monoclonal antibodies to CD4+ T cells have been found ineffective...

journal_title：Current opinion in rheumatology

authors： Kalden JR,Manger B

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review developments in the literature concerning work disability in the rheumatic diseases. RECENT FINDINGS:There have been three sets of studies to emerge in the last year. In the first, several studies analyze alternative research methods to document work disability. The second set uses qualitat...

journal_title：Current opinion in rheumatology

authors： Yelin E

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Dermatomyositis (DM) is a rare multisystem autoimmune disorder of adults and children that primarily affects skin and skeletal muscle. Classification systems of dermatomyositis, polymyositis, and the other idiopathic inflammatory myopathies focus primarily on features of muscle involvement. However, c...

journal_title：Current opinion in rheumatology

authors： Santmyire-Rosenberger B,Dugan EM

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Axial spondyloarthritis (axSpA) is a chronic inflammatory condition with articular and extra-articular manifestations. Remission, a state of absence of clinical and imaging signs of disease activity over time, is the goal of management. This review addresses the concept of minimal disease activity (MD...

journal_title：Current opinion in rheumatology

authors： Deodhar AA,Kumthekar A,Dubreuil M

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides a risk-stratified and evidence-based management for subsets of systemic sclerosis (SSc) patients in the first five years from disease onset. RECENT FINDINGS:Cardiopulmonary disease remains the primary cause of mortality in SSc patients. Morbidity and mortality in SSc-associated p...

journal_title：Current opinion in rheumatology

authors： Roofeh D,Khanna D

更新日期：2020-05-01 00:00:00

abstract：:Interstitial lung disease frequently complicates rheumatic disorders, especially polymyositis-dermatomyositis, rheumatoid arthritis, systemic sclerosis, and mixed connective tissue disease. In this article, we review the current data supporting the use of azathioprine, cyclophosphamide, chlorambucil, cyclosporine, and...

journal_title：Current opinion in rheumatology

authors： McCune WJ,Vallance DK,Lynch JP 3rd

更新日期：1994-05-01 00:00:00

abstract：:Neoplasia in an important cause of rheumatic disease. The mechanisms are either direct infiltration of the bone and joint, or indirect infiltration with manifestations distant from the site of neoplastic involvement. Many of the reports reviewed in this article center on direct associations. In particular, there is a ...

journal_title：Current opinion in rheumatology

authors： Schwarzer AC,Schrieber L

更新日期：1991-02-01 00:00:00

abstract：:Bacterial infections can clinically mimic a primary vasculitic syndrome and can directly cause a vasculitis that may respond to prompt recognition and treatment of the infection. Increasing direct and indirect evidence is establishing links between certain infections and vasculopathies, including aortitis, atheroscler...

journal_title：Current opinion in rheumatology

authors： Mandell BF,Calabrese LH

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Across the world, osteoarthritis is the most commonly occurring musculoskeletal disease of the elderly, affecting more than 25% of the population older than 60 years of age. By far the single greatest risk factor for the development of osteoarthritis is age, but a mechanism to explain this relation ha...

journal_title：Current opinion in rheumatology

authors： Verzijl N,Bank RA,TeKoppele JM,DeGroot J

更新日期：2003-09-01 00:00:00

abstract：:The eosinophilia-myalgia syndrome, which is associated with the ingestion of L-tryptophan that contained products, occurred as an epidemic in the United States in 1989. Eosinophilia-myalgia syndrome is similar in many ways to the toxic-oil syndrome, which occurred in Spain in 1981, and to diffuse fasciitis with eosino...

journal_title：Current opinion in rheumatology

authors： Silver RM

更新日期：1992-12-01 00:00:00

abstract：:Eosinophilic infiltration into skeletal muscle, although rare, has been described in a diverse group of conditions. It most commonly occurs in parasitic infection as focal eosinophilic myositis but can be a feature of systemic hypereosinophilic conditions such as eosinophilia-myalgia syndrome and idiopathic hypereosin...

journal_title：Current opinion in rheumatology

authors： Pickering MC,Walport MJ

更新日期：1998-11-01 00:00:00

abstract：:Cytokines and growth factors are important in bone tissue as mediators of cell-to-cell and matrix-to-cell communication. Cytokines also locally mediate the effects of several hormones on bone cells. Indeed, calciotropic hormones modulate the bone-cell production rate of these factors and, conversely, can change the nu...

journal_title：Current opinion in rheumatology

authors： de Vernejoul MC,Cohen-Solal M,Orcel P

更新日期：1993-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Current trends in the management of Behçet's syndrome will be reviewed in this article. RECENT FINDINGS:Biologic agents have gained increasing importance over the years in the management of Behçet's syndrome. Long-term results of observational studies have shown that anti-tumor necrosis factor agents...

journal_title：Current opinion in rheumatology

authors： Ozguler Y,Hatemi G

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Renal complications are important in scleroderma (systemic sclerosis) and include scleroderma renal crisis. This is a medical emergency that requires careful management. Recent cohort studies have highlighted key aspects of management and outcome and these are reviewed. RECENT FINDINGS:Two recent art...

journal_title：Current opinion in rheumatology

authors： Penn H,Denton CP

更新日期：2008-11-01 00:00:00

abstract：:The spectrum of clinical descriptions and clinicopathologic studies on patients with primary and secondary forms of antiphospholipid antibody syndrome continues to widen. Some differences exist for patients with lupus compared with those with Sjogren's syndrome. Some new thoughts regarding pathogenetic mechanisms and ...

journal_title：Current opinion in rheumatology

authors： McCarty-Farid GA

更新日期：1993-09-01 00:00:00

abstract：:In hip replacement, prophylaxis of thromboembolism with warfarin to 1.5 times control with respect to prothrombin time remains efficacious. Further reduction of the dosage has not met with success. Confirmatory studies on the usefulness of adjusted-dose heparin and low molecular weight heparin continue. Promising new ...

journal_title：Current opinion in rheumatology

authors： Yen D

更新日期：1992-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent advances in the analysis of genetic determinants of bone mass. It addresses both human and animal linkage studies as well as genetic manipulations in animals, inbred mouse models, and candidate gene analyses. RECENT FINDINGS:Recent studies have implicated novel regulatory ...

journal_title：Current opinion in rheumatology

authors： Baldock PA,Eisman JA

更新日期：2004-07-01 00:00:00