Mg2+-sensitive alterations in Ca2+ regulation associated with cell transformation.

abstract：:The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent Brij 58 effectively opened the erythrocyte plasma ...

journal_title：Journal of cellular physiology

authors： Kellermayer M,Ludány A,Miseta A,Kŏszegi T,Berta G,Bogner P,Hazlewood CF,Cameron IL,Wheatley DN

更新日期：1994-05-01 00:00:00

abstract：:A novel, serum albumin-binding glycoprotein of molecular weight (mw) 43,000 (43K protein) was initially purified from the culture medium of bovine aortic endothelial (BAE) cells (Sage, H., Johnson, C., and Bornstein, P., J. Biol. Chem. 259:3993-4007, 1984). Its secretion by normal mesenchymal cells and by transformed ...

journal_title：Journal of cellular physiology

authors： Sage H,Tupper J,Bramson R

更新日期：1986-06-01 00:00:00

abstract：:Bone is a multifaceted dynamic tissue, involved in mobility, mineral metabolism, and mesenchymal or stromal and hematopoietic progenitor or stem cells breading. Recently, an endocrine role has been attributed to bone due to its ability to produce at least two hormones (osteocalcin and fibroblast growth factor 23) and ...

journal_title：Journal of cellular physiology

authors： Agas D,Lacava G,Sabbieti MG

更新日期：2018-01-01 00:00:00

abstract：:Conditioned medium from Sertoli cells, prepared from testes of 20-day-old rats, contains component(s) that inhibit the incorporation of [3H]-thymidine into DNA of peritubular myoid cells (PMC) and inhibit the proliferation of PMC. These components are trypsin-resistant, heat-stable compounds having a molecular weight ...

journal_title：Journal of cellular physiology

authors： Tung PS,Fritz IB

更新日期：1991-06-01 00:00:00

abstract：:Production of inflammatory cytokines plays important roles in the response against tissue injury and in host defense. Alterations in the production of inflammatory cytokines may cause local or systemic inflammatory imbalance, culminating in organ failure or lethal systemic inflammation. The cholinergic anti-inflammato...

journal_title：Journal of cellular physiology

authors： Pereira MR,Leite PE

更新日期：2016-09-01 00:00:00

abstract：:The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal Zn homeostasis causes a variety of health problems including immunodeficiency and sensory dysfunctions. Previous studies had shown that Zn availability was also important for tumor growth and progression. The aim of the presen...

journal_title：Journal of cellular physiology

authors： Yu Z,Yu Z,Chen Z,Yang L,Ma M,Lu S,Wang C,Teng C,Nie Y

更新日期：2019-11-01 00:00:00

abstract：:Incubation of primary cultures of parenchymal hepatocytes in a conditioned medium (CM), collected over the first 3 h of serum-free rat hepatocyte culture (CM(0-3)), induces a time dependent increase of the frequency of apoptotic cells which is accompanied by prominent changes of cell morphology. Short-term treatment w...

journal_title：Journal of cellular physiology

authors： Bresgen N,Rolinek R,Hochleitner E,Lottspeich F,Eckl PM

更新日期：2004-03-01 00:00:00

abstract：:Suppression of PKC activity can selectively induce apoptosis in cells expressing a constitutively activated p21Ras protein. We demonstrate that continued expression of p21Ras activity is required in PKC-mediated apoptosis because farnesyltransferase inhibitors abrogated the loss of viability in p21Ras-transformed cell...

journal_title：Journal of cellular physiology

authors： Liou JS,Chen JS,Faller DV

更新日期：2004-02-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is one of the most frequently diagnosed cancers and the fourth leading cause of cancer-related death in the United States, suggesting that there is an urgent need to design novel strategies for achieving better treatment outcome of patients diagnosed with PDAC. Our previous stud...

journal_title：Journal of cellular physiology

authors： Wang Z,Ali S,Banerjee S,Bao B,Li Y,Azmi AS,Korc M,Sarkar FH

更新日期：2013-03-01 00:00:00

abstract：:Connective Tissue Growth Factor (CCN2/CTGF) and Nephroblastoma Overexpressed (CCN3/NOV) execute key functions within the hematopoietic compartment. Both are abundant in the bone marrow stroma, which is a niche for hematopoiesis and supports marrow function. Roles for 1,25-dihydroxyvitamin D3 (calcitriol) and all-trans...

journal_title：Journal of cellular physiology

authors： Piszczatowski RT,Rafferty BJ,Rozado A,Parziale JV,Lents NH

更新日期：2015-11-01 00:00:00

abstract：:We previously demonstrated that 4-oxoretinol (4-oxo-ROL) activated retinoic acid receptors (RARs) in F9 stem cells. We showed that 4-oxo-ROL inhibited the proliferation of normal human mammary epithelial cells (HMECs). To understand the mechanisms by which 4-oxo-ROL regulates HMEC growth we examined gene expression pr...

journal_title：Journal of cellular physiology

authors： Liu L,Derguini F,Gudas LJ

更新日期：2009-09-01 00:00:00

abstract：:Previous studies from our laboratory have shown that Chinese hamster V79 cells mutated to high level resistance to amphotericin B have a lower cellular level of cholesterol, the target molecule for the polyene antibiotic. Two amphotericin B-resistant (AMBR) mutants were each hybridized to their parental amphotericin B...

journal_title：Journal of cellular physiology

authors： Hidaka K,Akiyama SI,Kuwano M

更新日期：1981-01-01 00:00:00

abstract：:Radiotherapy remains a prime approach to adjuvant therapies in patients with early and advanced breast cancer. In spite of therapeutic success, metastatic progression in patients undergoing therapy, limits its application. However, effective therapeutic strategies to understand the cellular and molecular machinery in ...

journal_title：Journal of cellular physiology

authors： Rajput S,Kumar BN,Banik P,Parida S,Mandal M

更新日期：2015-03-01 00:00:00

abstract：:The polyphenolic compounds curcumin and quercetin increased sensitivity of ovarian cancer cells (CAOV3 and SKOV3) to cisplatin. The effect was obtained when the compounds were added simultaneously with cisplatin, as well as when they were added 24 h before. High serum levels of certain cytokines, for example interleuk...

journal_title：Journal of cellular physiology

authors： Chan MM,Fong D,Soprano KJ,Holmes WF,Heverling H

更新日期：2003-01-01 00:00:00

abstract：:Reactivation of dormant chick erythrocyte (CE) nuclei was studied by fusing chick red cells with rat myoblasts, HeLa cells, and chick fibroblasts. Heterokaryons representing different stages of nuclear reactivation were fixed and examined for nuclear antigens using polyclonal patient autoantisera reacting with mammali...

journal_title：Journal of cellular physiology

authors： Nyman U,Lanfranchi G,Bergman M,Ringertz NR

更新日期：1984-08-01 00:00:00

abstract：:In this review, we focused our attention on the more important natural extracellular matrix (ECM) molecules (collagen and fibrin), employed as cellular scaffolds for tissue engineering and on a class of semi-synthetic materials made from the fusion of specific oligopeptide sequences, showing biological activities, wit...

journal_title：Journal of cellular physiology

authors： Rosso F,Marino G,Giordano A,Barbarisi M,Parmeggiani D,Barbarisi A

更新日期：2005-06-01 00:00:00

abstract：:This study describes the alterations induced by Interleukin-1 alpha and -beta (IL-1 alpha and IL-1 beta) on fibroblast-synthesized extracellular matrix. Fibroblasts were grown between pieces of dentin or in collagen-coated Terasaki wells for 3 or 6-9 weeks to create 3-dimensional cell-containing matrices constituted p...

journal_title：Journal of cellular physiology

authors： Qwarnström EE,MacFarlane SA,Page RC

更新日期：1989-06-01 00:00:00

abstract：:We report that cultured vascular endothelial cells release into the culture medium a vasoconstrictor peptide, a substance we call an endothelium-derived constricting factor (EDCF). Conditioned medium from cultured bovine aortic and pulmonary artery endothelial cells caused sustained, dose-dependent isometric constrict...

journal_title：Journal of cellular physiology

authors： O'Brien RF,Robbins RJ,McMurtry IF

更新日期：1987-08-01 00:00:00

abstract：:Nowadays, epigenetics covers a crucial role in different fields of science. The enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2), is a big proponent of how epigenetic changes can affect the initiation and progression of several diseases. Through its catalytic activi...

journal_title：Journal of cellular physiology

authors： Sanna L,Marchesi I,Melone MAB,Bagella L

更新日期：2018-09-01 00:00:00

abstract：:Guanine nucleotides and pertussis toxin were used to test for the involvement of a guanine nucleotide binding protein in the vasopressin V1 receptor-mediated stimulation of protein kinase C activity in Swiss 3T3 cells. Addition of vasopressin in the presence of [gamma-32P]ATP and digitonin caused a marked and rapid in...

journal_title：Journal of cellular physiology

authors： Erusalimsky JD,Rozengurt E

更新日期：1989-11-01 00:00:00

abstract：:Despite being densely packed with chromatin, nuclear bodies and a nucleoskeletal network, the nucleus is a remarkably dynamic organelle. Chromatin loops form and relax, RNA transcripts and transcription factors move diffusively, and nuclear bodies move. We show here that RNA splicing speckled domains (splicing speckle...

journal_title：Journal of cellular physiology

authors： Zhang Q,Kota KP,Alam SG,Nickerson JA,Dickinson RB,Lele TP

更新日期：2016-06-01 00:00:00

abstract：:Exosomes extracted from mesenchymal stem cells (MSCs) was reported to reduce myocardial ischemia/reperfusion damage. Besides, stromal-derived factor 1 (SDF1a) functions as cardiac repair after myocardial infarction (MI). Therefore, the present study aims to identify whether exosomes (Exo) released from SDF1-overexpres...

journal_title：Journal of cellular physiology

authors： Gong XH,Liu H,Wang SJ,Liang SW,Wang GG

更新日期：2019-08-01 00:00:00

abstract：:Di- and tripeptides and peptide mimetics such as beta-lactam antibiotics are efficiently reabsorbed from the tubular lumen by a high-affinity peptide transporter. We have recently identified and characterized this H+-coupled high-affinity peptide transport system in the porcine proximal tubular cell line LLC-PK1. Here...

journal_title：Journal of cellular physiology

authors： Wenzel U,Diehl D,Herget M,Kuntz S,Daniel H

更新日期：1999-03-01 00:00:00

abstract：:Mesenchymal stem cells (MSC) represent emerging cell-based therapies for diabetes and associated complications. Ongoing clinical trials are using exogenous MSC to treat type 1 and 2 diabetes, cardiovascular disease and non-healing wounds due to diabetes. The majority of these trials are aimed at exploiting the ability...

journal_title：Journal of cellular physiology

authors： Smith AN,Muffley LA,Bell AN,Numhom S,Hocking AM

更新日期：2012-09-01 00:00:00

abstract：:The present study was performed to clarify second messenger signaling in parathyroid hormone (PTH)-induced c-fos gene expression, to characterize the participation of the c-fos gene in the regulation of osteoblast proliferation and function as well as osteoclast-like cell formation by PTH and to compare these effects ...

journal_title：Journal of cellular physiology

authors： Kano J,Sugimoto T,Kanatani M,Kuroki Y,Tsukamoto T,Fukase M,Chihara K

更新日期：1994-11-01 00:00:00

abstract：:Restenosis after angioplasty or stent is a major clinical problem. While long noncoding RNAs (lncRNAs) are implicated in a variety of diseases, their role in restenosis is not well understood. This study aims to investigate how dysregulated lncRNAs and messenger RNAs (mRNAs) contribute to restenosis. By microarray ana...

journal_title：Journal of cellular physiology

authors： Zhou Y,He X,Liu R,Qin Y,Wang S,Yao X,Li C,Hu Z

更新日期：2019-02-10 00:00:00

abstract：:The synthesis and turnover of metabolically labeled proteoglycans from medium, cell layer, and substratum-associated compartments were characterized in four cell lines of fibroblastic origin, including a fibrosarcoma line, and in the murine melanoma cell type, B16.F10. Substantial differences were apparent between the...

journal_title：Journal of cellular physiology

authors： Piepkorn M,Hovingh P,Linker A

更新日期：1988-05-01 00:00:00

abstract：:Detailed information regarding the synthesis rates of individual protein components is important in understanding the assembly and dynamics of the cytoskeletal matrix of eukaryotic cells. As an approach to this topic, the dual isotope technique of Clark and Zak (J. Biol. Chem., 256:4863-4870, 1981), was employed to me...

journal_title：Journal of cellular physiology

authors： Mitchell JJ,Low RB,Woodcock-Mitchell JL

更新日期：1990-06-01 00:00:00

abstract：:The significance of low pH-induced stimulation of osteoclastic bone resorption has recently been questioned following the finding that embryonic chick osteoclasts were only weakly stimulated by extremely low pH (6.5) and that the effect was transient, apparently due to cytotoxicity. Although low pH in the range 6.8-7....

journal_title：Journal of cellular physiology

authors： Murrills RJ,Stein LS,Dempster DW

更新日期：1993-03-01 00:00:00

abstract：:With the long-range goals of elucidating the biochemical genetics and the phenotypic expression, both in vitro and in vivo, of mutator strains of mammalian cells, we have isolated and partially characterized a series of drug-resistant mutants from a subline a feeder-dependent parental mouse teratocarcinoma line (PSA-1...

journal_title：Journal of cellular physiology

authors： Aizawa S,Loeb LA,Martin GM

更新日期：1983-04-01 00:00:00