Types of synapses contacting the soma of corticotectal cells in the visual cortex of the cat.

abstract：:Layer V pyramidal cells in the intermediate part of the cerebral cortex enter the lumbar spinal gray, but not the cervical spinal gray matter, during the first postnatal week. To study if the ingrowth of intermediate corticospinal axons into the lumbar spinal gray is guided by a diffusible tropic factor, we co-culture...

journal_title：Neuroscience

authors： Joosten EA,Gispen WH,Bär PR

更新日期：1994-03-01 00:00:00

abstract：:Rats received bilateral lesions of the nucleus basalis magnocellularis by infusion of ibotenic acid. Fourteen days later, osmotic minipumps releasing human recombinant nerve growth factor (0.3 micrograms/day) were implanted subcutaneously. Starting one month after the lesion, spatial learning of the animals was tested...

journal_title：Neuroscience

authors： Dekker AJ,Gage FH,Thal LJ

更新日期：1992-01-01 00:00:00

abstract：:Sleep is strongly implicated in learning, especially in the reprocessing of recently acquired memory. Children with intellectual disability (ID) tend to have sleep-wake disturbances, which may contribute to the pathophysiology of the disease. Given that sleep is partly controlled by the circadian clock, we decided to ...

journal_title：Neuroscience

authors： Renaud J,Dumont F,Khelfaoui M,Foisset SR,Letourneur F,Bienvenu T,Khwaja O,Dorseuil O,Billuart P

更新日期：2015-11-12 00:00:00

abstract：:Experimental autoimmune neuritis (EAN) is the animal model of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) that is the most common subtype of Guillain-Barre syndrome (GBS). While neuropathic pain is a common symptom of GBS, its underlying mechanisms remain elusive. Central sensitization, particularly...

journal_title：Neuroscience

authors： Zhang Z,Zhang ZY,Fauser U,Schluesener HJ

更新日期：2008-03-18 00:00:00

abstract：:In two experiments, we combined a semantic blocked naming paradigm with anodal transcranial direct current stimulation (tDCS) to shed light on the neural correlates of the semantic interference (SI) effect. In particular, prior to the naming task, anodal tDCS was applied over the left superior temporal gyrus (STG, Exp...

journal_title：Neuroscience

authors： Pisoni A,Papagno C,Cattaneo Z

更新日期：2012-10-25 00:00:00

abstract：:In contrast to other rhythmic tasks such as running, the preferred movement rate in cycling does not minimize energy consumption. It is possible that neurophysiological mechanisms contribute to the choice of cadence, however this phenomenon is not well understood. Eleven participants cycled at a fixed workload of 125 ...

journal_title：Neuroscience

authors： Sidhu SK,Lauber B

更新日期：2020-08-10 00:00:00

abstract：:Stimulant-induced exocytosis has been demonstrated in sympathetic ganglia of the rat by in vitro incubation of excised ganglia in the presence of tannic acid, which stabilizes vesicle cores after their exocytotic release. Sites of exocytosis were observed along non-synaptic regions of the surfaces of neuron somata and...

journal_title：Neuroscience

authors： Zaidi ZF,Matthews MR

更新日期：1997-10-01 00:00:00

abstract：:TREK-1 is a member of the two-pore-domain potassium channel family which is expressed predominantly in the CNS. Using an anti-peptide polyclonal antiserum, we have determined the distribution of TREK-1 in the brain and spinal cord of adult rats. Specificity of the antiserum was tested using a TREK-1-transfected cell l...

journal_title：Neuroscience

authors： Hervieu GJ,Cluderay JE,Gray CW,Green PJ,Ranson JL,Randall AD,Meadows HJ

更新日期：2001-01-01 00:00:00

abstract：:Previous studies have shown oxidative damage resulting from amyloid Abeta exposure to cultured cells and in murine models. A target of oxidation is 14-3-3 which comprises a group of proteins involved in kinase activation and chaperone activity. The present study shows glycoxidative damage, as revealed with mono and bi...

journal_title：Neuroscience

authors： Santpere G,Puig B,Ferrer I

更新日期：2007-06-08 00:00:00

abstract：:Allotetrahydrodeoxycorticosterone (THDOC) belongs to a class of pregnane neurosteroidal compounds that enhance brain inhibition by interacting directly with GABAA signaling, mainly through an increase in tonic inhibitory current. Here, we addressed the role of THDOC in the modulation of interictal- and ictal-like acti...

journal_title：Neuroscience

authors： Herrington R,Lévesque M,Avoli M

更新日期：2014-01-03 00:00:00

abstract：:Glomeruli are functional units of the olfactory bulb responsible for early processing of odor information encoded by single olfactory receptor genes. Glomerular neural circuitry includes numerous external tufted (ET) cells whose rhythmic burst firing may mediate synchronization of bulbar activity with the inhalation c...

journal_title：Neuroscience

authors： Ma J,Lowe G

更新日期：2007-02-09 00:00:00

abstract：:The transforming growth factor beta-activated kinase 1 (TAK1), a member of the Mitogen-activated protein kinase kinase kinase family, is characterized as a key regulator in inflammatory and apoptosis signaling pathways. The aim of the present study was to evaluate the role of the TAK1 pathway in experimental traumatic...

journal_title：Neuroscience

authors： Zhang D,Hu Y,Sun Q,Zhao J,Cong Z,Liu H,Zhou M,Li K,Hang C

更新日期：2013-05-15 00:00:00

abstract：:In vitro receptor autoradiography was used to localize, quantify and characterize [125I-Tyr8]bradykinin binding sites in all major spinal cord segments of normal rats and animals subjected to various chemical treatments and surgical lesions. [125I-Tyr8]bradykinin specific binding sites were predominantly located to su...

journal_title：Neuroscience

authors： Lopes P,Kar S,Chrétien L,Regoli D,Quirion R,Couture R

更新日期：1995-10-01 00:00:00

abstract：:The presence of subgroups in vomeronasal sensory neurons has been known in various animals. To elucidate possible functional subdivisions in the guinea-pig accessory olfactory bulb, the combined studies with GTP-binding protein immunohistochemistry, electrophysiological and optical recordings were carried out. Gi2 alp...

journal_title：Neuroscience

authors： Sugai T,Sugitani M,Onoda N

更新日期：1997-08-01 00:00:00

abstract：:In amyotrophic lateral sclerosis (ALS) there is a selective degeneration of motor neurons leading to muscle paralysis and death. The mechanism underlying cell demise in ALS is not fully understood, but involves the activation of different proteolytic enzymes, including the caspase family of cysteine proteases. We have...

journal_title：Neuroscience

authors： Wootz H,Weber E,Korhonen L,Lindholm D

更新日期：2006-12-01 00:00:00

abstract：:To examine changes in corticostriatal synaptic transmission in rats with ethanol withdrawal syndrome, intracellular and extracellular responses to subcortical white matter stimulation were recorded in neostriatal slice preparations. The resting membrane potential, input resistance and depolarizing postsynaptic potenti...

journal_title：Neuroscience

authors： Yamamoto Y,Nakanishi H,Takai N,Shimazoe T,Watanabe S,Kita H

更新日期：1999-01-01 00:00:00

abstract：:Significant alterations in glutamatergic neurotransmission have been reported in major depressive disorder (MDD) that could underlie psychiatric traits. Studies were mainly interested in synaptic dysfunction in the prefrontal cortex, a key structure involved in depressive-like behavior, however hippocampus has been sh...

journal_title：Neuroscience

authors： Dutar P,Tolle V,Kervern M,Carcenac C,Carola V,Gross C,Savasta M,Darmon M,Masson J

更新日期：2019-01-01 00:00:00

abstract：:Long-term hyperexcitability was found after unilateral, permanent middle cerebral artery occlusion in exofocal neocortical areas of the adult mouse [Mittmann et al. (1998) Neuroscience 85, 15-27]. The aim of the present study was to test the hypothesis in an identical paradigm of ischemia. whether alterations in the d...

journal_title：Neuroscience

authors： Qü M,Mittmann T,Luhmann HJ,Schleicher A,Zilles K

更新日期：1998-07-01 00:00:00

abstract：:Using arsenazo III as an intracellular indicator to monitor the calcium transients elicited by voltage-clamp depolarizing pulse, the effect of prolonged in vitro lithium treatment on excitation--contraction coupling in frog twitch muscle fibres was investigated. Incubation in 10 mM Li+ Ringer's solution for 2 days cau...

journal_title：Neuroscience

authors： Zhu PH,Fu DX

更新日期：1990-01-01 00:00:00

abstract：:Metabolic activity was mapped in the cerebellar cortex and its major inputs and projection targets in monkeys performing visually guided reaching with the left forelimb. Normal monkeys and monkeys deprived of visual input to the right cerebral hemisphere by right optic tract section, combined in some cases with forebr...

journal_title：Neuroscience

authors： Savaki HE,Kennedy C,Sokoloff L,Mishkin M

更新日期：1996-11-01 00:00:00

abstract：:Social bonds, especially attachment relationships, are crucial to our health and happiness. However, what we know about the neural substrates of these bonds is almost exclusively limited to rodent models and correlational experiments in humans. Here, we used socially monogamous non-human primates, titi monkeys (Callic...

journal_title：Neuroscience

authors： Maninger N,Hinde K,Mendoza SP,Mason WA,Larke RH,Ragen BJ,Jarcho MR,Cherry SR,Rowland DJ,Ferrer E,Bales KL

更新日期：2017-04-21 00:00:00

abstract：BACKGROUND:Spasticity and rigidity are serious complications associated with spinal traumatic or ischemic injury. Clinical studies show that tizanidine (Tiz) is an effective antispasticity agent; however, the mechanism of this effect is still not clear. Tiz binds not only to α2-adrenoreceptors (AR) but also to imidazol...

journal_title：Neuroscience

authors： Fuchigami T,Kakinohana O,Hefferan MP,Lukacova N,Marsala S,Platoshyn O,Sugahara K,Yaksh TL,Marsala M

更新日期：2011-10-27 00:00:00

abstract：:Sulfoglucuronyl carbohydrate is the terminal moiety of neolacto-oligosaccharides, expressed on several glycoproteins of the immunoglobulin superfamily involved in cell-cell recognition and on two glycolipids. Sulfoglucuronyl carbohydrate is temporally and spatially regulated in the developing nervous system. It appear...

journal_title：Neuroscience

authors： Nair SM,Zhao Z,Chou DK,Tobet SA,Jungalwala FB

更新日期：1998-08-01 00:00:00

abstract：:Zinc plays an important role in synaptic signaling in the mammalian cerebral cortex. Zinc is sequestered into presynaptic vesicles of subpopulations of glutamatergic neurons and is released by depolarization, in a calcium-dependent manner. As the majority of mechanisms that have been suggested to participate in experi...

journal_title：Neuroscience

authors： Brown CE,Dyck RH

更新日期：2003-01-01 00:00:00

abstract：:Arising from studies on the amnesia that follows site-specific physical or chemical lesions, the acquisition and consolidation of certain behavioral tasks has been demonstrated to be associated with different hippocampal subregions. Although not absolute, spatial learning is reliant on the dorsal region of the hippoca...

journal_title：Neuroscience

authors： Scully D,Fedriani R,Desouza IE,Murphy KJ,Regan CM

更新日期：2012-05-03 00:00:00

abstract：:Neurotransmitter and headache target localization in the trigeminal ganglia (TG) might increase the understanding of sites of action, and mechanisms related to headache therapy. The overall aim of the study was to investigate the presence of migraine targets in the TG with particular emphasis on pituitary adenylate cy...

journal_title：Neuroscience

authors： Frederiksen SD,Warfvinge K,Ohlsson L,Edvinsson L

更新日期：2018-11-21 00:00:00

abstract：:Using an indirect immunofluorescence method the distribution of vasoactive intestinal peptide (VIP) immunoreactivity was studied in human foetus and newborn infant spinal cord and dorsal root ganglia. Further, for comparison some newborn infant brains were also investigated. Vasoactive intestinal peptide-like immunore...

journal_title：Neuroscience

authors： Charnay Y,Chayvialle JA,Said SI,Dubois PM

更新日期：1985-01-01 00:00:00

abstract：:The present studies were conducted to test the hypothesis that systemically inactive doses of cannabinoids suppress inflammation-evoked neuronal activity in vivo via a peripheral mechanism. We examined peripheral cannabinoid modulation of spinal Fos protein expression, a marker of neuronal activity, in a rat model of ...

journal_title：Neuroscience

authors： Nackley AG,Suplita RL 2nd,Hohmann AG

更新日期：2003-01-01 00:00:00

abstract：:Two radial maze tasks, random foraging and delayed spatial win-shift, have been used to investigate, in rats, the functions and inter-relationships of structures connected through the corticostriatal loops, such as the prelimbic cortex, nucleus accumbens, ventral pallidum and mediodorsal thalamus. The random foraging ...

journal_title：Neuroscience

authors： Keating GL,Winn P

更新日期：2002-01-01 00:00:00

abstract：:The pontine micturition center or Barrington's nucleus (BN) - besides regulating micturition - co-regulates the activity of other pelvic viscera such as the colon and genitals. At present, this issue is gaining particular importance due to: (i) recent findings of α-synuclein in BN, (ii) known urinary dysfunction in pa...

journal_title：Neuroscience

authors： Blanco L,Ros CM,Tarragón E,Fernández-Villalba E,Herrero MT

更新日期：2014-04-25 00:00:00