Abstract：
:This article presents a comparison of Liouville-Green (LG) calculations and exact solutions of 2- and 3-dimensional cochlea models. The agreement is in general quite good. For certain choices of the model parameters, however, the 2- and 3-dimensional LG solutions show appreciable errors in the region just beyond the location of maximum amplitude of the basilar membrane response. The origin of these errors appears to be the non-uniqueness of the (complex) LG wave number k(x) in 2- and 3-dimensional models: the 'eikonal equation' from which k(x) has to be solved has multiple roots. To study this problem somewhat deeper, the properties of the locus of k=k(x) formed when x is varied, are investigated. Erratic behaviour of the LG solution is found to occur when this root locus approaches one of the saddle points of a complex function of k- called Q(k)- which plays the major role in the eikonal equation. Apart from this specific problem, the LG approximation is very well suited to unravel the mechanisms governing wave propagation and attenuation in the cochlea. The analysis shows clearly why and how the response of the basilar membrane builds up to a maximum and which factors cause a turnover and a rapid decrease to occur, in both the long-wave and the short-wave cases. A special discussion is dedicated to the relation between the LG approximation and the absence of wave reflection in cochlea models of the type studied.
journal_name
Hear Resjournal_title
Hearing researchauthors
de Boer E,Viergever MAdoi
10.1016/0378-5955(82)90071-5subject
Has Abstractpub_date
1982-10-01 00:00:00pages
131-55issue
2eissn
0378-5955issn
1878-5891pii
0378-5955(82)90071-5journal_volume
8pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:This study was performed to elucidate the contribution of the stapedial artery (SA)--which has been considered to be independent of the vertebrobasilar system--to blood flow in the ear by observing ear blood flow in Sprague-Dawley rats. A laser-Doppler (LD) probe was positioned on the bony wall of the cochlear basal t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00310-1
更新日期：2003-12-01 00:00:00
abstract：:The effects of genotype and diet on age-related hearing loss were evaluated using auditory brainstem response (ABR) thresholds and post-mortem cochlear histopathology in 5 inbred mouse strains, CBA/H-T6J (CH), DBA/2J (D2), C57BL/6J (B6), BALB/cByJ (BY) and WB/ReJ (WB), and their 10 F1 hybrid strains. The mice had been...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00107-f
更新日期：1995-08-01 00:00:00
abstract：:Noise, hearing loss, and electronic signal distortion, which are common problems in military environments, can impair speech intelligibility and thereby jeopardize mission success. The current study investigated the impact that impaired communication has on operational performance in a command and control environment ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.10.007
更新日期：2017-06-01 00:00:00
abstract：AIM:This study aimed to investigate the efficiency of Magnitude Squared Coherence (MSC) and Spectral F test (SFT) for the detection of auditory steady state responses (ASSR) obtained by amplitude-modulated noises. MATERIAL AND METHODS:Twenty individuals (12 women) without any history of neurological or audiological di...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.05.017
更新日期：2016-09-01 00:00:00
abstract：:Carboplatin is currently being used as an anticancer drug against human cancers. However, high dose of carboplatin chemotherapy resulted in hearing loss in cancer patients. We have shown that carboplatin-induced hearing loss was related to dose-dependent oxidative injury to the cochlea in rat model. However, the time ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.01.011
更新日期：2004-05-01 00:00:00
abstract：:Electrical stimulation of the cochlea with a multiple-electrode array is best accomplished using pulsatile instead of continuous stimulation. The optimum shapes of electrical pulses for this purpose are still uncertain due to a lack of knowledge about their stimulation efficiency and requirements of the encoding strat...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90045-2
更新日期：1989-06-01 00:00:00
abstract：:Dominant white spotting W/W(v) and W(v)/W(v) mice are well-known mutants that lack strial intermediate cells in their cochlea and manifest hereditary sensorineural hearing loss. We recently reported marked thickening of and IgG deposition on the basement membrane of strial capillaries in W/W(v) mutant mice, similar to...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2005.05.013
更新日期：2005-11-01 00:00:00
abstract：:Auditory brainstem implants (ABIs) can restore useful hearing to persons with deafness who cannot benefit from cochlear implants. However, the quality of hearing restored by ABIs rarely is comparable to that provided by cochlear implants in persons for whom those are appropriate. In an animal model, we evaluated eleme...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.03.009
更新日期：2018-06-01 00:00:00
abstract：:It is known that the threshold of an acoustically induced middle-ear-muscle (MEM) reflex can be lowered by the simultaneous presentation of a second tone (facilitator), which is presented to the ipsilateral or contralateral ear at a level below the acoustic reflex threshold (ART) of the facilitator itself (Sesterhenn ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00039-7
更新日期：1997-06-01 00:00:00
abstract：:In this study 9 human temporal bones from 8 individuals were fixed with Karnovsky solution by perilymphatic perfusion within 1-3 h after death and examined using the "block-surface method' (Spoendlin and Brun, 1974; Spoendlin and Schrott, 1987) and the "micro-dissection method' (Johnsson and Hawkins, 1967). The audiog...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(95)00158-1
更新日期：1995-11-01 00:00:00
abstract：:Superposition of point processes has often been suggested as an abstract model for the generation of neural discharge patterns due to its simplicity (input spike trains are simply merged and then retransmitted by the model neuron). The properties of the superposition of two renewal processes are examined in relation t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(86)90015-8
更新日期：1986-01-01 00:00:00
abstract：:Glutamate, gamma aminobutyric acid (GABA) and glycine receptors have different properties depending on the specific subunit combination utilized. The subunit composition of amino acid receptors may help to shape the responses of neurons and can provide a diversity of response properties in different neuronal types and...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/s0378-5955(00)00127-1
更新日期：2000-09-01 00:00:00
abstract：:Voice emotion is a fundamental component of human social interaction and social development. Unfortunately, cochlear implant users are often forced to interface with highly degraded prosodic cues as a result of device constraints in extraction, processing, and transmission. As such, individuals with cochlear implants ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2017.01.006
更新日期：2017-09-01 00:00:00
abstract：:Psychophysical measures of the electrically stimulated human auditory system were obtained for different types of symmetric and asymmetric charge-balanced waveforms. Absolute detection thresholds of biphasic, pseudomonophasic, and 'alternating monophasic' current waveforms delivered by a bipolar intra-cochlear electro...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.08.006
更新日期：2005-02-01 00:00:00
abstract：:Damage to auditory nerve fibers that expresses with suprathreshold sounds but is hidden from the audiogram has been proposed to underlie deficits in temporal coding ability observed among individuals with otherwise normal hearing, and to be present in individuals experiencing chronic tinnitus with clinically normal au...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.11.010
更新日期：2017-02-01 00:00:00
abstract：:Auditory brainstem responses (ABR) to clicks and noise bursts of various frequency bands and intensities were recorded in two bottlenosed dolphins, Tursiops truncatus. The purpose was to assess contributions of various parts of the cochlear partition to ABR and travelling wave velocity in the cochlea. At band-pass fil...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(00)00234-3
更新日期：2001-01-01 00:00:00
abstract：:Glutamate plays a role in hair cell afferent transmission, but the receptors that mediate neurotransmission between outer hair cells (OHCs) and type II ganglion neurons are not well defined. A previous study using in situ hybridization showed that several kainate-type glutamate receptor (KAR) subunits are expressed in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.05.001
更新日期：2014-08-01 00:00:00
abstract：:Mutations in GJB2 account for the majority of recessive forms of prelingual hearing loss. However, in most previous studies it was not possible to distinguish between congenital (present at birth) and non-congenital prelingual hearing loss. In the present study, the frequency of GJB2 alleles in 20 newborns with bilate...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.06.012
更新日期：2004-11-01 00:00:00
abstract：:Tympanosclerosis is a condition leading to a calcification process in the middle ear, and often develops after chronic inflammation of the middle ear. Since osteopontin (OPN) has been shown to participate in the pathological calcification, we here investigated whether OPN is involved in the process of calcification in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(00)00260-4
更新日期：2001-03-01 00:00:00
abstract：:We obtained just-noticeable differences (jnds) for the intensity of pure tones following a forward masker. The masker was a 100-ms burst of narrow-band noise centered at 1000 Hz presented at 90 dB SPL; the pure-tone signal was at 1000 Hz and was 25 ms in duration. The masker-signal delay was 100 ms. Under these condit...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(91)90107-k
更新日期：1991-10-01 00:00:00
abstract：:Receptors which bind the neurotrophins NGF, BDNF, NT-3 and NT-4/5 were shown to be present in cochlear and vestibular ganglion cells during development, implying a neurotrophic role for these molecules in the inner ear. We have found by in situ hybridization that cochlear and vestibular sensory epithelial cells expres...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(94)90286-0
更新日期：1994-02-01 00:00:00
abstract：:It is widely appreciated that the key predictor of the pitch of a sound is its periodicity. Neural structures which support pitch perception must therefore be able to reflect the repetition rate of a sound, but this alone is not sufficient. Since pitch is a psychoacoustic property, a putative cortical code for pitch m...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2010.04.015
更新日期：2011-01-01 00:00:00
abstract：:The purpose of this study was to investigate horizontal plane localization and interaural time difference (ITD) thresholds for 14 adult cochlear implant recipients with hearing preservation in the implanted ear. Localization to broadband noise was assessed in an anechoic chamber with a 33-loudspeaker array extending f...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.02.007
更新日期：2014-06-01 00:00:00
abstract：:Drugs of the salicylate family (aspirin-like drugs) are reversibly ototoxic. Electrophysiologic and ultrastructural evidence suggests an impairment of the sensory hair cells of the cochlea following salicylate treatment. In addition, since these drugs can cause vasoconstriction, the ototoxicity of salicylates may also...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(93)90108-d
更新日期：1993-09-01 00:00:00
abstract：:To assess the effects of extracochlear electrical stimulation on cochlear structure, guinea pigs were implanted and stimulated with single middle ear electrodes either at round window or promontory sites, and their cochleae examined by transmission electron microscopy. Implanted but unstimulated, or unimplanted contro...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90214-0
更新日期：1987-11-01 00:00:00
abstract：:In mammals, the cochlear sensory epithelium becomes quiescent early during development. After the first postnatal week, there is no cell replacement or proliferation, and severe damage leads to permanent deafness. Supporting cells' trans-differentiation has been suggested as a way to regenerate cochlear hair cells aft...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.12.002
更新日期：2019-03-01 00:00:00
abstract：:Adenosine plays a major cytoprotective role during ischemia and conditions of oxidative stress. Previous studies in our laboratory indicate that oxidative stress induces expression of the A1 adenosine receptor (A1AR) via activation of nuclear factor (NF)-kappaB. In this study, we tested whether noise exposure could in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/S0378-5955(03)00344-7
更新日期：2004-02-01 00:00:00
abstract：:Both sound exposure and gentamicin treatment cause damage to sensory hair cells in the peripheral chick auditory organ, the basilar papilla. This induces a regeneration response which replaces hair cells and restores auditory function. Since functional recovery requires the re-establishment of connections between rege...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00150-0
更新日期：1997-11-01 00:00:00
abstract：:The tympanic membrane is a key component of the human auditory apparatus. Good estimates of tympanic membrane mechanical properties are important to obtain realistic models of middle ear mechanics. Current literature values are almost all derived from direct mechanical tests on cut-out strips. For a biomedical specime...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2012.05.001
更新日期：2012-08-01 00:00:00
abstract：:Several studies have reported an increased incidence of auditory dysfunction among HIV/AIDS patients. We used auditory HEI-OC1 cells in cell viability, flow cytometry and caspases 3/7-activation studies to investigate the potential ototoxicity of fourteen HIV antiretroviral agents: Abacavir, AZT, Delavirdine, Didenosi...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2014.01.005
更新日期：2014-04-01 00:00:00
