Abstract:
:In the present study the combination of tamoxifen and bromocriptine was tried for the suppression of prolactin in prolactin secreting adenomas which were resistant to suppression with bromoergocriptine alone. 10 women under treatment with 2.5-10 mg of parlodel (bromocriptine) for pituitary tumours of various sizes were additionally treated with tamoxifen 10-20 mg. (nolvadex) daily. Two patients had a previous incomplete resection for chromophobe adenomas. The other patients refused operation. Two women were also studied who did not tolerate a bromoergocriptine therapy because of side effects. In 6 of the 10 women with combination treatment a satisfactory suppression of the prolactin was observed. Four women were cleared of their amenorrhoea and galactorrhoea. One woman conceived. One woman lost her frigidity. Three women, among those the two with severe side effects from bromoergocriptine, tolerated the combined treatment well. Four women showed no success with the combined treatment. The effectiveness of the combined treatment was not correlated with the size of the tumour nor the clinical or biochemical baseline. The results lead to the conclusion that tamoxifen is capable of improving the suppression of prolactin or render the adenomas suppressible in a large number of cases.
journal_name
Geburtshilfe Frauenheilkdjournal_title
Geburtshilfe und Frauenheilkundeauthors
Völker W,Gehring WG,von zur Mühlen A,Schneider Jdoi
10.1055/s-2008-1037161subject
Has Abstractpub_date
1982-11-01 00:00:00pages
790-7issue
11eissn
0016-5751issn
1438-8804journal_volume
42pub_type
杂志文章abstract::The importance of yeast infections in obstetrics was investigated in 200 pregnant women and their newborns. In the maternity patients the vagina was tested shortly before the delivery and the mouth of the neonates was tested 1 day prior to the discharge from the hospital. In 22% of the pregnant women and in 8,4% of th...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-05-01 00:00:00
abstract::34 patients received an intravenous bolus injection of 2 g ceftizoxime over 5 min at various times before abdominal or vaginal hysterectomy. Ceftizoxime concentrations in myometrium were substantially higher than in salpinges and endometrium. Tissue concentrations of 4 micrograms/g could be maintained for at least 3 h...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036734
更新日期:1983-11-01 00:00:00
abstract::Holoprosencephaly is a malformation complex, in which the foetal forebrain (prosencephalon) fails to cleave. The aetiology of holoprosencephaly is heterogeneous. In the last years, a new malformation syndrome has been described, including holoprosencephaly, postaxial polydactyly, congenital heart defects and normal ka...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1023813
更新日期:1992-12-01 00:00:00
abstract::Cervical smears of 554 women using IUDs were examined. The following criteria were evaluated: 1. Age distribution, 2. maturation index of the vaginal epithelium, 3. vaginal flora, 4. cytologic criteria of inflammation, 5. period of time between insertion of the IUD and the cytological examination, 6. final cytologic d...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037354
更新日期:1981-03-01 00:00:00
abstract::During the cancer check-up of a 46-year-old woman a PAP V was diagnosed in the cervical scrapings. The atypical cells of the abrasion specimens from the corpus uteri arouse strong suspicion of malignancy. Connected with the clinical data, this finding primarily indicated a metastatic involvement of the inner genitals....
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036064
更新日期:1987-12-01 00:00:00
abstract::Ovarian function suppression (OFS) for treating breast cancer in pre-menopausal women was introduced for the first time in the late 19th century as bilateral oophorectomy. It was not until the 1960s that the oestrogen receptor was identified and a test for detecting endocrine sensitivity of the breast cancer was devel...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-0042-106389
更新日期:2016-05-01 00:00:00
abstract::In a study comprising 172 patients who had been abdominally or vaginally hysterectomised, the effectivity of short-term prophylaxis with cefotaxim on various infection parameters was examined. The 100 patients of the prophylaxis group showed a significant reduction (p less than 0.01) of postoperative fever and of pelv...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036203
更新日期:1985-01-01 00:00:00
abstract::The regular Huffman vaginoscope is fitted with an endotracheal sleeve to obtain a balloon vaginoscope. The balloon vaginoscope makes inspection of the cervix in children much easier, and facilitates the removal of foreign bodies from the vagina of children. Vaginoscopy can be learned easier with the balloon vaginoscop...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::On account of the good prognosis for patients with breast cancer, improving or maintaining the quality of life in the aftercare period is becoming more and more important. In particular, the increasing usage of aromatase inhibitors in the past few years has led to an increased incidence of vaginal atrophy with symptom...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0033-1350876
更新日期:2013-10-01 00:00:00
abstract::As a part of the Central European Study a long-term study of the pubertal development of 687 Hungarian girls was undertaken and the findings compared with those of a cross-sectional study of a group of girls from Münster. In addition to assessment of the breast and pubic hair according to Tanner's classification, the ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1026624
更新日期:1988-11-01 00:00:00
abstract::Plasma levels of PGE2, PGA2 and PGF2 alpha were determined by radioimmunoassay in maternal cubital vein blood of 210 women and once during pregnancy. In the course of pregnancy plasma levels of these prostaglandins varied considerably: 0,09-1,83 ng PGE2/ml, 0,12-2,8 ng PGA2/ml and 0,04-0,5 ng PGF2 alpha/ml. At term (4...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-09-01 00:00:00
abstract::A 65 year old woman, who had vaginal hysterectomy 24 years ago, was admitted to the hospital because of a lower abdominal tumor. When laparotomy was performed a retroperitoneal myoma with a weight of 1,8 kg and 22 cm in diameter was found. ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037345
更新日期:1980-04-01 00:00:00
abstract::Blood vessels are visible in an average of 80% of patients on whom colposcopy is performed. This percentage share increases if there are pathological changes. The following vascular types occur as characteristic criteria in cervical intraepithelial neoplasia (CIN) and in carcinoma, their classification being based on ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036721
更新日期:1983-10-01 00:00:00
abstract::During the last six years we observed four malaria relapses shortly after delivery. In three cases the relapse occurred subsequent to Caesarean section, and in one case shortly after normal uncomplicated delivery. Case histories revealed that these women had previously stayed in the tropical or subtropical zones. The ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036513
更新日期:1984-11-01 00:00:00
abstract::In recent years, the incidence of tuberculosis in pregnancy in the industrialised countries has increased. Tuberculosis in pregnancy is associated with an increased risk for the mother and child. Even if no figures are available for Germany, an increase in the number of tuberculosis cases among pregnant women can be a...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0774-7924
更新日期:2019-04-01 00:00:00
abstract::In early 1989, we sent a questionnaire to all 89 Departments of Gynaecology in Austria. Questions covered the number and type of gynaecological operations performed, perioperative management, and diagnosis and treatment of descent and urinary incontinence. 90% of questionnaires were returned. We found that currently 2...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1026481
更新日期:1990-04-01 00:00:00
abstract::Treatment with monoclonal antibodies (mabs) has become an established component of oncological therapy. The monoclonal antibodies available for this purpose are mainly administered intravenously in individually adapted doses according to body weight over longer treatment times. For other chronic diseases such as, for ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0034-1368173
更新日期:2014-04-01 00:00:00
abstract::Subcutaneous mastectomy was performed in 335 patients between 1974 and 1982. In 265 of these, original mammographies were available which were analysed retrospectively and compared with the final histological finding of the subcutaneous mastectomy preparation. The rate of newly discovered non-invasive carcinomas in th...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036377
更新日期:1985-09-01 00:00:00
abstract::Introduction It is still unclear in the literature whether low vitamin D levels play a role in the pathogenesis of polycystic ovary syndrome (PCOS), especially with respect to the regulation of anti-Müllerian hormone (AMH). Therefore, we aimed to investigate whether there could be a relationship between vitamin D defi...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-0871-6831
更新日期:2019-07-01 00:00:00
abstract::In 49 carcinomas of the endometrium of varying clinical stages the estrogen and progesterone receptors were studied by charcoal absorption methods. The cases were studied between 1979 and 1981. 64% of the investigated cases were receptor positive, 35% were receptor negative. Estrogen receptors were detected in 61% and...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037179
更新日期:1982-12-01 00:00:00
abstract::We report on a 13 year old girl with a FSH, secreting pituitary tumour, who was presented with recurrent bleeding disorders. Gynaecological examination revealed large cystic ovarian tumours on both sides. The endocrinological work-up showed high serum levels of oestradiol and FSH, and low serum levels of testosterone ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1026437
更新日期:1990-01-01 00:00:00
abstract::Routine screening of maternal antibodies showed presence of anti-Fya (from the antigen Fya of Duffy Blood Group System) in a 25 years old second time pregnant woman. The spectroscopic examination of amniotic fluid has been carried out and gave values which decrease within Zone II. In the beginning of 39. week of gesta...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-07-01 00:00:00
abstract::A case of a 21-year-old woman with a botryoid sarcoma of the cervix uteri, who consulted a specialist for women's diseases because of non stopping haemorrhages in childbed, is reported. Neither radical operation nor radiation nor treatment with cytostatica could arrest the extreme impetuous growth of this tumor. ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract::In a prospective, randomised study we compared the clinical properties of the established Redon drain with a new type of drain called "slit drain". Both types of drains were examined regarding the amount of drained fluid, the time elapsing until removal of the drain, the frequency of occlusion of the lumen as well as ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-1026165
更新日期:1991-05-01 00:00:00
abstract::Complex malformations of the skeleton of the cranium and face are mostly first discovered by the obstetrician. Almost all anomalies can be corrected already at infant age by means of update craniofacial surgery, provided they are diagnosed well in time and treatment is initiated directly. Surgery should be performed b...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036113
更新日期:1989-11-01 00:00:00
abstract::Surgery of the fallopian tubes has today developed into pelviscopic surgery. The development of suitable instruments such as the tube set, a new endocoagulation method were prerequisites for this development. Operative therapeutic pelviscopic surgery is a development past laparotomy. It is now possible to treat adhesi...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::The authors report on five cases of massive atonic uterine haemorrhage which could be influenced neither by repeated application of oxytocin nor by methylergometrin. Intramyometrial application of PGF2 alpha succeeded in inducing a satisfactory uterine tone and stopping the haemorrhage. With regard to own experiences ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1026501
更新日期:1988-04-01 00:00:00
abstract::Today, echography can be considered as routine diagnosis in every pregnancy. Besides the detection of growth retardation very often in early stages of the fetal life malformations can be diagnosed incompatible with postnatal life. Reviewing the cases of the II. Women's Department of Obstetrics and Gynaecology in Vienn...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037231
更新日期:1980-10-01 00:00:00
abstract::The prognostic significance of the lysosomal protease cathepsin D in breast cancer was evaluated in a retrospective study. Cathepsin D was measured in 346 deep-frozen (-70 degrees C) cytosol specimens of primary breast carcinomas (1982-1990). Among the established prognostic factors, only axillary lymph node involveme...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1022337
更新日期:1994-10-01 00:00:00
abstract::From 1977-1989, 298 ectopic pregnancies were treated pelviscopically at the Dept. of Gynaecology Hospital of the University of Kiel. 26 tubes were already ruptured. In 251 patients (84%), organ preserving treatment was possible, 205 treatment by longitudinal salpingotomy. 46 tubal abortions were extracted. In 47 patie...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1026197
更新日期:1991-07-01 00:00:00