[Antibiotic prevention in gynecology. Concentrations of ceftizoxime in the serum, myometrium, endometrium and fallopian tubes].

Abstract:

:34 patients received an intravenous bolus injection of 2 g ceftizoxime over 5 min at various times before abdominal or vaginal hysterectomy. Ceftizoxime concentrations in myometrium were substantially higher than in salpinges and endometrium. Tissue concentrations of 4 micrograms/g could be maintained for at least 3 hours. The ceftizoxime tissue concentrations attained in myometrium, endometrium and salpinges justify therapeutic studies and controlled prospective clinical trials on the prevention of postoperative wound infections with this antibiotic.

authors

Daschner F,Just HM,Brändle J,Zahn V

doi

10.1055/s-2008-1036734

subject

Has Abstract

pub_date

1983-11-01 00:00:00

pages

683-5

issue

11

eissn

0016-5751

issn

1438-8804

journal_volume

43

pub_type

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