[The erbB gene family: significance for tumor development, prognosis and new therapeutic modalities].

abstract：:Therapeutic results in advanced cervical cancer have not been showing any progress for more than 30 years. Only by means of systemic therapy does it seem possible, that further treatment results may be obtained similar to those in squamous cell carcinoma of the head and neck. Therefore, between 1985 and 1990 we tried ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kaufmann M,Schmid H,Junkermann H,Schönig T,von Fournier D,Bastert G

更新日期：1991-06-01 00:00:00

abstract：:With the development of a National Cancer Plan published in 2012, Germany has followed the recommendations of the WHO and the EU. The first area of action listed in Germany's National Cancer Plan is improving the early detection of cancer. Both citizens and medical specialists are encouraged to take responsibility the...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Simoes E,Brucker S,Beckmann MW,Ortmann O,Albring C,Wallwiener D

更新日期：2013-03-01 00:00:00

abstract：:In the following up of the diagnosis of the female sterility we practised 123 hysterosalpingographies (HSG) from 1972--1978. Presupposition was the proof of the ovulation by base temperature. The HSG is the beginning of the diagnosis to recognize the intracanalicular changes of the uterus and to avoid senseless treatm...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Fettig O,Heilmann R

更新日期：1981-07-01 00:00:00

abstract：:The ovarian carcinoma-associated antigen CA-125 was determined in 144 women with various gynecological tumors (ovarian, breast, uterine), by using the heterologous monoclonal antibody OC-125. In 90% of the malignant ovarian tumors positive CA-125 values were correct, whereas their negative values were correct in 88% o...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Sevelda P,Salzer H,Dittrich C,Spona J

更新日期：1985-11-01 00:00:00

abstract：:In 74 patients with normal pregnancy, termination of pregnancy was induced during 1980-1983 for medical reasons (12%) or for eugenic reasons (88%) in the second trimenon of pregnancy. We compared endocervical PG-E2 gel application (if necessary, several doses of 0.5 mg PG-E2 gel every 4-6 hours in 25 cases) with intra...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schmidt W,Rabe D,Hendrik HJ

更新日期：1985-04-01 00:00:00

abstract：:Doppler blood flow measurements allow differentiation of malignant lesions, that are characterised by an abnormal vascularity. The accuracy of this method is limited due to the physiological flow variation in normal breast parenchyma and in tumours. Magnetic resonance imaging in combination with contrast agents can al...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Madjar H,Prömpeler H,Schürmann R,Göppinger A,Breckwoldt M,Pfleiderer A

更新日期：1993-12-01 00:00:00

abstract：:The prognostic value of the PCNA-proliferative fraction as compared to conventional clinical and histomorphological factors (FIGO-stage, tumour type, histological grading, lymph node status, size of residual tumour) was investigated in 81 ovarian cancer patients. Categorisation of PCNA-expression into tumours with low...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schönborn I,Minguillon C,Reles A,Bartel U,Lichtenegger W

更新日期：1996-07-01 00:00:00

abstract：:Without Rh-IgG prophylaxis the incidence of rhesus sensitisation increases in D-negative women with the number of subsequent pregnancies. However, our case report of a d-negative multipara demonstrates that foetal erythroblastosis does not necessarily occur in a pregnancy with initially high anti-D titres. ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kölbl H,Riss P

更新日期：1987-04-01 00:00:00

abstract：:Introduction: To evaluate, if targeted strip biopsies decrease trauma/pain perception while maintaining diagnostic accuracy in patients with the diagnosis of high-grade squamous intraepithelial lesions of the uterine cervix. Patients and Methods: Between July 1st and December 31st 2014 we performed colposcopically dir...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schneider A,Wagner K,Rakozy C,Stolte C,Bothur-Schäfer P,Welcker T,Choly N,Roesgen A,Rothe H,Böhmer G

更新日期：2015-10-01 00:00:00

abstract：:Comparative cytogenetic studies of a primary squamous cell carcinoma of the uterine cervix and the local recurrence of the same tumor following radio therapy are reported. The microscopic features of both tumors were identical. The cytogenetic features of both tumors were almost identical as to the degree of ploidy, t...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Dehnhard F,Breinl H,Schüssler J,Wehler V

更新日期：1976-11-01 00:00:00

abstract：:The therapy of choice for breast cancer patients requiring adjuvant chemo- or radiotherapy is increasingly guided by the principle of weighing the individual effectiveness of the therapy against the associated side effects. This has only been made possible by the discovery and validation of modern biomarkers. In the l...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schmidt M,Fasching PA,Beckmann MW,Kölbl H

更新日期：2012-09-01 00:00:00

abstract：:The article reports on a clinically unusual case of a patient with carcinoma of the breast. The "initial sign" of the disease was relapsed hypermenorrhoic permanent bleeding with severe bleeding anaemia caused by a metastatic growth in the uterus. Surgery or cytostatic treatment did not seem possible at the outset, be...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Beck T,Melchert F,Schweikhart G,Brockerhoff P

更新日期：1985-05-01 00:00:00

abstract：:In a prospective study, 31 unselected patients with urge or urge incontinence, where previous treatment had been unsuccessful, were given repeated instillations of Lidocain gel for 11 days. Detailed histories were obtained by questionnaire both before instituting and after termination of the therapy. A cystourethroton...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Gassner K,Briel RC

更新日期：1988-08-01 00:00:00

abstract：:Among 8739 deliveries premature rupture of the membranes was noticed in 1.792 cases. The premature rupture of the membranes occurred mostly during the night. During the 8 hours of the night from 2200-0600 hours the membranes ruptured more frequently than during the 16 hours of the day. One would expect that the forewa...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Warkentin B

更新日期：1983-03-01 00:00:00

abstract：:Premature rupture (= PR) of the amnion is a serious complication even for the mature child if it occurs earlier than 24 hours before birth. To keep the interval as short as possible, the authors induce labour from week 35/0 in case of PR, provided the Bishop score is greater than 7. If the bishop score is lower, they ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Goeschen K,Fuchs AR,Fuchs F,Husslein P,Rasche M

更新日期：1984-12-01 00:00:00

abstract：:Aim: Nodal status remains one of the most important prognostic factors in breast cancer. The cellular and molecular reasons for the spread of tumor cells to the lymph nodes are not well understood and there are only few predictors in addition to tumor size and multifocality that give an insight into additional mechani...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Hack CC,Häberle L,Geisler K,Schulz-Wendtland R,Hartmann A,Fasching PA,Uder M,Wachter DL,Jud SM,Loehberg CR,Lux MP,Rauh C,Beckmann MW,Heusinger K

更新日期：2013-02-01 00:00:00

abstract：:Prognostic factors influencing survival in 235 very low birthweight prematures (< or = 1500 g) born between 1986 and 15.11. 1993 at the Department of Obstetrics and Gynaecology, University Hospital of Cologne, were retrospectively evaluated. Chromosomal anomalies and severe congenital malformations were excluded. Of 1...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Hamm W,Göhring UJ,Günther M,Kribs A,Neuhaus W,Roth B,Bolte A

更新日期：1995-03-01 00:00:00

abstract：:Report on the rare event of a complete ischemia of the right arm immediately postpartum. The infant was delivered by Caesarean Section because of cervical dystocia and fetal distress. The umbilical cord was twice around the neck and the ischemia of the right arm appeared to be due to spasm of the axillary artery. Trea...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Muth H,Engelbrecht R

更新日期：1976-12-01 00:00:00

abstract：:By means of ultrasound and fetal electrocardiography the diagnosis of twin pregnancies can be made prenatally without any reservation; the diagnosis is even possible in the first half of pregnancy. Comparative analysis of two approximately equal collectives of in all 602 twin pregnancies--1,45% of all births in the ye...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Bolte A,Zippel HH,Berendes R,Meyer V

更新日期：1978-04-01 00:00:00

abstract：:The pre-operative and post-operative findings in 56 patients with urinary stress incontinence are compared amongst each other and with the result of 24 continent control patients. The 56 patients were selected prospectively. The urethral closure pressure with stress and the stress quotient in urethral cystometry are s...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Voigt R,Voigt P

更新日期：1982-05-01 00:00:00

abstract：:Cystometric finding of 93 urge incontinent and 157 not urge incontinent women were compared by evaluating the following 4 parameters: uninhibited detrusor contractions, first desire to void, maximum cystometric capacity and bladder compliance. Of these 4 parameters only uninhibited detrusor contractions were significa...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Bänninger U,Kunz J

更新日期：1981-05-01 00:00:00

abstract：:Sulproston was used to terminate 125 pregnancies from 13 to 41 weeks duration, between 1.1.1979 and 31.12.1980. The indications for termination of pregnancy included medical problems, genetic disorders and neural tube defects. Sulproston alone was used in 30 cases. In the remaining 95 cases the cervix uteri was treate...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Ponnath H,Weitzel H,Benthin D

更新日期：1981-12-01 00:00:00

abstract：:In many cases, the sonography of the endometrium requires an exact pre-therapeutical interpretation. Apart from a hysteroscopy, this can take place by means of an improved version of a contrast hysterosonography, i.e. the Gel-KHSG. The technique and examination results are described here. This simple examination metho...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Klug PW

更新日期：1991-06-01 00:00:00

abstract：:We report on a prenatal diagnosis with high alpha-fetoprotein level and a positive acetylcholinesterase activity in a presumptive amniotic fluid. Ultrasonographic examinations revealed a hydropic fetus with a nuchal cystic hygroma. Chromosome analysis of the aborted foetus ascertained the suspected Turner syndrome. Th...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Koske-Westphal T,Müller-Holve W

更新日期：1985-02-01 00:00:00

abstract：:Between October 1978 and December 1980 165 diagnostic laparoscopies were carried out because of the suspected diagnosis of primary tubal infertility. In this preselected series 27.9% of the cases had normal findings. It was remarkable that the previous diagnosis was not confirmed in 21 cases which had a prior infertil...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Scheidel P,Hepp H

更新日期：1982-11-01 00:00:00

abstract：:Since the publication of the updated German guideline in 2015, the recommendations for performing pelvic lymphadenectomy (LAE) in patients with vulvar cancer (VSCC) have changed considerably. The guideline recommends surgical lymph node staging in all patients with a higher risk of pelvic lymph node involvement. Howev...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Woelber L,Bommert M,Prieske K,Fischer I,Zu Eulenburg C,Vettorazzi E,Harter P,Jueckstock J,Hilpert F,de Gregorio N,Iborra S,Sehouli J,Ignatov A,Hillemanns P,Fuerst S,Strauss HG,Baumann K,Beckmann M,Mustea A,Meier W,

更新日期：2020-12-01 00:00:00

abstract：:In a prospective study 265 patients with threatened abortions were divided into 2 groups. One group of 134 patients received treatment with Oestradiol benzoat and hydroxyprogesterone capronat. The other group of 131 patients received no hormonal treatment. Of the group treated with hormones 40.7% of the women had an a...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Berle P,Behnke K

更新日期：1977-02-01 00:00:00

abstract：:As a key area of gynaecology, urogynaecology has undergone impressive changes in the past few years. Together with the high prevalence of functional pelvic floor disorders, modern anaesthesia procedures and the introduction of new, innovative minimally invasive operation techniques have led to a dramatic increase in t...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Naumann G,Kölbl H

更新日期：2012-03-01 00:00:00

abstract：:The presence of vulvar condylomata acuminata shows evidence HPV infection of the vulva. 49 patients with such lesions came to our hospital for laser treatment. At that time, none of the patients were aware of their cervical disease. Colposcopy and biopsy of the cervix revealed in eight (16%) of the 49 patients CIN I a...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Menton M,Neeser E,Oettling G,Marzusch K,Smyczek-Gargya G

更新日期：1992-08-01 00:00:00

abstract：:Prognosis of carcinoma of the breast depends on a number of factors. Besides tumour staging, these parameters include the number of axillary lymph nodes with metastatic growths, the status of the hormonal receptors, and the histological type of the tumour, especially the tumour grading and the rate of growth correlate...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kühn W,von Fournier D,Leppien G,Rummel HH,Müller A,Dick G

更新日期：1983-06-01 00:00:00