The response of prolactin to chlorpromazine stimulation in men with hypogonadotrophic hypogonadism and early pubertal boys: relationship to sex steroid exposure.

abstract：:It is believed that the study of gonadal function of the child should be regarded as a whole, beginning with the fetus and ending with the adolescent. Gonadal function depends upon 3 levels of activities: 1) central level (extra-hypothalamic, hypothalamic, and anterior pituitary); 2) an intermediate level (gonadal a...

journal_title：Clinical endocrinology

authors： Forest MG,De Peretti E,Bertrand J

更新日期：1976-09-01 00:00:00

abstract：RATIONALE:In vitro fertilization (IVF) is a common treatment for infertility. In mice, IVF is associated with development of glucose intolerance. However, human data are limited regarding the metabolic, endocrine and inflammatory effects of IVF therapy in IVF-conceived pregnancies. OBJECTIVE:To explore effects of IVF ...

journal_title：Clinical endocrinology

authors： Coussa A,Hasan HA,Barber TM

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To compare the value of the thyroid imaging reporting and data system proposed by Kwak (KWAK TI-RADS) and the 2015 American Thyroid Association (ATA) guidelines for diagnosis of medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC). To confirm the role of cell block (CB)-assisted fine-needle...

journal_title：Clinical endocrinology

authors： Li J,Li H,Yang Y,Zhang X,Qian L

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Malignant phaeochromocytomas are rare and highly aggressive tumours. This retrospective study evaluated the outcome of combined chemotherapy with cyclophosphamide, vincristine and dacarbazine (also known as CVD regimen). METHODS:Patients with histologically and radiologically confirmed malignant phaeochromoc...

journal_title：Clinical endocrinology

authors： Deutschbein T,Fassnacht M,Weismann D,Reincke M,Mann K,Petersenn S

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE AND DESIGN:Depot somatostatin analogues are well accepted as either adjuvant or primary therapy for acromegaly, and their long dosage intervals facilitate adherence to treatment. Our objective was to evaluate whether lanreotide Autogel 120 mg, every 4-8 weeks, was as effective in controlling acromegaly as lan...

journal_title：Clinical endocrinology

authors： Lucas T,Astorga R,Spanish-Portuguese Multicentre Autogel Study Group on Acromegaly.

更新日期：2006-09-01 00:00:00

abstract：:Two patients with profound hypocalcaemia due to uraemia and hypoparathyroidism respectively presented with alterations of mental state as their dominant symptom. 1-Alpha-hydroxycholecalciferol (1-alpha-OHD3) was chosen as the principal therapy because of its potency and rapid action. In both patients the plasma calciu...

journal_title：Clinical endocrinology

authors： Gertner JM,Hodsman AB,Neuberger JN

更新日期：1976-09-01 00:00:00

abstract：OBJECTIVE:The disruption between the brain and the spinal cord leads to a decentralized sympathetic nervous system in people with chronic, cervical spinal cord lesions. These tetraplegic subjects are prone to disorders of energy metabolism and osteoporosis, and they experience alterations in their body composition with...

journal_title：Clinical endocrinology

authors： Hjeltnes N,De Groot P,Birkeland KI,Falch JA,Iversen PO

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Previous studies suggesting effects of metyrapone on extra-adrenal corticosteroid metabolism have involved significant alterations in plasma cortisol. We have therefore studied effects of metyrapone on urinary excretion of steroids in a group of patients treated concurrently with hydrocortisone...

journal_title：Clinical endocrinology

authors： Raven PW,Checkley SA,Taylor NF

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:Small, dense low-density lipoproteins (LDL) are a feature of the metabolic syndrome (MS) but their predictive role still remains to be established. We performed a 2-year follow-up study in 124 subjects with MS (63 +/- 6 years), as defined by the American Heart Association/National Heart, Lung and Blood Instit...

journal_title：Clinical endocrinology

authors： Rizzo M,Pernice V,Frasheri A,Di Lorenzo G,Rini GB,Spinas GA,Berneis K

更新日期：2009-06-01 00:00:00

abstract：:A 31-year old female presented with recurrent episodes of post-prandial hypoglycaemic symptoms. Basal serum levels of ACTH, cortisol, GH, insulin and glucagon were normal. An adrenaline test demonstrated a normal peripheral response. An exercise test failed to produce ACTH, cortisol or FFA responses. Insulin (0.1 u/kg...

journal_title：Clinical endocrinology

authors： Corcos AP,Weidenfeld J,Levy J,Barash V,Siegel RA,Gutman A,Chowers I

更新日期：1983-10-01 00:00:00

abstract：OBJECTIVE:Oestradiol sensitizes the pituitary to GnRH, while gonadotrophin surge attenuating factor (GnSAF) may oppose this action. Using the LH response to GnRH during treatment with FSH as an in vivo bioassay for GnSAF, we tested the hypothesis that the augmented LH response to GnRH in the late follicular phase is re...

journal_title：Clinical endocrinology

authors： Dimitraki M,Messini CI,Dafopoulos K,Gioka T,Koutlaki N,Garas A,Georgoulias P,Messinis IE

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to investigate the possibility of impaired lipolysis of triglyceride-rich lipoproteins in patients with abdominal visceral fat accumulation by assessing two major lipolytic enzymes in the plasma, lipoprotein lipase (LPL) and hepatic lipase (HL). DESIGN AND PATIENTS:A total of 3...

journal_title：Clinical endocrinology

authors： Kobayashi J,Tashiro J,Murano S,Morisaki N,Saito Y

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To elucidate the interaction between insulin and dehydroepi-androsterone (DHEA) concentrations, we evaluated serum DHEA and DHEA-sulphate (DHEA-S) levels in diabetic patients with hyperinsulinaemia. PATIENTS AND DESIGN:Twenty-four subjects with non-insulin dependent diabetes mellitus, 12 hyperinsulinaemic su...

journal_title：Clinical endocrinology

authors： Yamaguchi Y,Tanaka S,Yamakawa T,Kimura M,Ukawa K,Yamada Y,Ishihara M,Sekihara H

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Precocious pubarche (PP) has been linked to higher prevalence of metabolic disturbances and polycystic ovary syndrome (PCOS). The aim of the study was to assess echocardiographic parameters in PP girls and to analyse their relationship with androgens and insulin resistance (IR). DESIGN:Case-control study. P...

journal_title：Clinical endocrinology

authors： Satler F,Vieira Rdo A,Firpo C,Spritzer PM

更新日期：2016-03-01 00:00:00

abstract：CONTEXT:It is unclear if people who develop stress hyperglycaemia have underlying abnormal glucose metabolism, an exaggerated hormonal response to stress, or both. Similarly, it is unknown whether stress hyperglycaemia predicts future glucose intolerance. OBJECTIVE:To determine the relationship between illness severit...

journal_title：Clinical endocrinology

authors： Carmen Wong KY,Wong V,Ho JT,Torpy DJ,McLean M,Cheung NW

更新日期：2010-02-01 00:00:00

abstract：:Growth hormone and prolactin are secreted episodically in man and experimental animals. To investigate physiologic mechanisms of GH and PRL secretion, a series of experiments were performed in individual, unanaesthetized male and female rats. GH secretion in the male rat is characterized by intermittent surges that oc...

journal_title：Clinical endocrinology

authors： Terry LC,Saunders A,Audet J,Willoughby JO,Brazeau P,Martin JB

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To explore differences in irisin concentrations between lean adolescents with PCOS and age- and body mass index (BMI)-matched controls and examine the associations of irisin with core features of the syndrome. DESIGN:Cross-sectional study. PATIENTS:Lean females with PCOS, aged 13-21 years. MEASUREMENTS:Phy...

journal_title：Clinical endocrinology

authors： Bacopoulou F,Athanasopoulos N,Efthymiou V,Mantzou A,Aravantinos L,Vlahopoulos S,Deligeoroglou E

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Hypercortisolaemia is associated with an increased risk of cardiovascular disease (CVD), either through a direct action on the myocardium or by increased traditional cardiovascular risk factors. The aim of this study was to investigate whether the alterations in the ECG in Cushing's disease (CD) are predictab...

journal_title：Clinical endocrinology

authors： Alexandraki KI,Kaltsas GA,Vouliotis AI,Papaioannou TG,Trisk L,Zilos A,Korbonits M,Besser GM,Anastasakis A,Grossman AB

更新日期：2011-05-01 00:00:00

abstract：CONTEXT:Two main forms of amiodarone-induced thyrotoxicosis (AIT) exist. Type 1 AIT is a form of iodine-induced hyperthyroidism. Its management is complex and includes thionamides, potassium perchlorate and, occasionally, thyroidectomy. Type 2 AIT is a destructive thyroiditis, responds to glucocorticoids, and usually d...

journal_title：Clinical endocrinology

authors： Bogazzi F,Bartalena L,Dell'Unto E,Tomisti L,Rossi G,Pepe P,Tanda ML,Grasso L,Macchia E,Aghini-Lombardi F,Pinchera A,Martino E

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:Augmented brown adipose tissue (BAT) mass and activity lead to higher basic metabolic rate which is beneficial against obesity. Our aim was to investigate whether habitual (i.e. usual weekly participation) physical activity is linked with BAT activity and mass in humans, in a group of patients undergoing (18)...

journal_title：Clinical endocrinology

authors： Dinas PC,Nikaki A,Jamurtas AZ,Prassopoulos V,Efthymiadou R,Koutedakis Y,Georgoulias P,Flouris AD

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Adequate uterine growth is an essential component of pubertal induction with exogenous oestradiol in those with hypogonadism. Poor uterine development will render the individual vulnerable in the context of fertility. We assessed uterine size using ultrasound in those who had undergone pubertal induction trea...

journal_title：Clinical endocrinology

authors： Burt E,Davies MC,Yasmin E,Cameron-Pimblett A,Mavrelos D,Talaulikar V,Conway GS

更新日期：2019-12-01 00:00:00

abstract：:Phaeochromocytomas and paragangliomas (PPGLs) are rare tumours that arise from the adrenal medulla or extra-adrenal sympathetic or parasympathetic paraganglia. Recent advances in genetics have greatly enhanced understanding of the pathogenesis and molecular physiology of PPGL. Concomitantly, advances in molecular imag...

journal_title：Clinical endocrinology

authors： Ryder SJ,Love AJ,Duncan EL,Pattison DA

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:Over 1% of the UK population is receiving thyroid hormone replacement with l-thyroxine (T4). However, many patients complain of persistent lethargy and related symptoms on T4 even with normal TSH levels. To date there has been no large study to determine whether this is related to thyroxine replacement or coi...

journal_title：Clinical endocrinology

authors： Saravanan P,Chau WF,Roberts N,Vedhara K,Greenwood R,Dayan CM

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:We determined the effect of subclinical hyperthyroidism (defined as low circulating TSH with normal serum free T4) and subclinical hypothyroidism (raised serum TSH with normal free T4) on fasting levels of blood lipids. DESIGN:Prospective study of lipid concentrations in patients identified as having abnorma...

journal_title：Clinical endocrinology

authors： Parle JV,Franklyn JA,Cross KW,Jones SR,Sheppard MC

更新日期：1992-11-01 00:00:00

abstract：INTRODUCTION:Previous studies investigating cardiovascular (CV) risk in obese women with polycystic ovary syndrome (PCOS) have been potentially confounded by not adequately accounting for body weight. OBJECTIVE:To assess if PCOS increases CV risk independently in young obese women by examining carotid intima-media wal...

journal_title：Clinical endocrinology

authors： Kahal H,Aburima A,Ungvari T,Rigby AS,Dawson AJ,Coady AM,Vince RV,Ajjan RA,Kilpatrick ES,Naseem KM,Atkin SL

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Obesity is characterized by hyperleptinaemia, which is associated with diabetes, hypertension and coronary heart disease. The aim of this study was to determine if body fat and muscle measures predict the natural increase in leptin over 2·6 years in older adults. METHODS:A total of 190 subjects (50% females)...

journal_title：Clinical endocrinology

authors： Antony B,Jones G,Stannus O,Blizzard L,Ding C

更新日期：2013-11-01 00:00:00

abstract：:Twenty women with secondary hypogonadism and four normal women in the early follicular phase of the cycle were treated for 7 days with 10, 50 or 100 micrograms synthetic LHRH administered intramuscularly at 4 h intervals. Concentrations of pituitary and ovarian hormones in plasma were measured at intervals during the ...

journal_title：Clinical endocrinology

authors： Vaughan Williams CA,McNeilly AS,Baird DT

更新日期：1983-07-01 00:00:00

abstract：:The adrenolytic agent, 2,2-bis[2-chlorophenyl-4-chlorophenyl] 1,1 dichloroethane (o,p'-DDD), was used over a 20-month period following surgery in a 2 3/12-year-old girl for treatment of adrenocortical carcinoma. The child remained free of disease and was maintained on glucocorticoid and mineralo-corticoid supplements ...

journal_title：Clinical endocrinology

authors： Greig F,Oberfield SE,Levine LS,Ghavimi F,Pang S,New MI

更新日期：1984-04-01 00:00:00

abstract：:Nutrition and growth during infancy are an emerging issue because of their potential link to metabolic health disorders in later life. Moreover, prolonged breast-feeding appears to be associated with a lower risk of obesity than formula feeding. Human milk is a source of various hormones and growth factors, namely adi...

journal_title：Clinical endocrinology

authors： Savino F,Fissore MF,Liguori SA,Oggero R

更新日期：2009-12-01 00:00:00

abstract：:We have previously reported that L-thyroxine treated patients may often have elevated serum T4 concentrations and yet show no clinical signs of hyperthyroidism. We found that such patients had normal serum T3 concentrations. The present study explored the relationship between serum T3 and T4 and dosage of L-thyroxine....

journal_title：Clinical endocrinology

authors： Rendell M,Salmon D

更新日期：1985-06-01 00:00:00