Abstract：
:The HML and HMR loci carry unexpressed copies of MATa and MAT alpha information, and a replica of that information is transposed to MAT during mating-type interchange in Saccharomyces yeasts. A negative control mechanism keeps silent the information located at the HML and HMR loci. We mapped these loci by constructing strains in which these loci are expressed. In these strains, the mating type of the segregants is dependent upon the allele at HML and HMR. This novel approach is independent of their switching function. HML is located on the left arm of chromosome III distal to his4 by about 26.8 centimorgans (cM). HMR maps on the right arm of the same chromosome distal to thr4 by about 39.8 cM and proximal to MAL2 by about 1.0 cM. The results allow the exact placement of these loci and are in accord with the observations made by Harashima and Oshima (1976).
journal_name
Geneticsjournal_title
Geneticsauthors
Klar AJ,McIndoo J,Hicks JB,Strathern JNsubject
Has Abstractpub_date
1980-10-01 00:00:00pages
315-20issue
2eissn
0016-6731issn
1943-2631journal_volume
96pub_type
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