Abstract:
:Under hypoxic (95% N2 + 5% CO2) perfusion, electrophysiological effects of L-carnitine on canine papillary muscles were studied using standard microelectrode techniques. During hypoxic perfusion for 60 min, resting membrane potential (RMP), action potential amplitude (APA) and maximum upstroke velocity of phase 0 were decreased, and action potential duration (APD) and effective refractory period (ERP) were shortened. Application of L-carnitine 25 mM under hypoxic perfusion increased RMP and APA and prolonged APD and ERP significantly. As effects of L-carnitine during hypoxic perfusion might be that of hypertonicity, effects of sucrose of the same tonicity as L-carnitine were studied under hypoxia. Sucrose did not cause significant changes on various parameters of action potential compared with hypoxic perfusion. It was suggested that the increase in RMP, and the prolongation of APD and ERP might be caused by an increase in intracellular ATP content. The findings in this study could be an explanation of possible antiarrhythmic effects of L-carnitine.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Hayashi H,Suzuki Y,Abe M,Nishihara K,Masumura Y,Kamikawa T,Kobayashi A,Yamazaki Ndoi
10.1016/s0022-0736(84)80030-8subject
Has Abstractpub_date
1984-01-01 00:00:00pages
85-9issue
1eissn
0022-0736issn
1532-8430journal_volume
17pub_type
杂志文章abstract::This is the first report on the stable occurrence of ventricular quadrigeminy as a manifestation of concealed bigeminy in a case of fixed and late coupled ventricular extrasystoles. A 46-year-old man is reported in whom the period of ventricular bigeminy alternated with the period of ventricular quadrigeminy. Coupling...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/s0022-0736(00)80106-5
更新日期:2000-01-01 00:00:00
abstract::The authors comment on the present status of computerized electro-cardiogram (ECG) works in Japan and demonstrate the preliminary tentative results of CSE (common standards for quantitative electrocardiography) data analysis using the Nagoya program. The more detailed results of the performance of several programs in ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(88)90087-8
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Analysis of ST-segment elevation for assessment of patients with suspected acute coronary occlusion is in widespread use for diagnostic and prognostic purposes. In this study, changes in the QRS complex also were analyzed to determine if these changes that are seldom used clinically can provide additional pr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2006.09.001
更新日期:2007-01-01 00:00:00
abstract::The sensitivity of an extensive electrocardiographic examination to local cardiac regions was evaluated by comparison with findings in vectorcardiographic leads. Evaluation consisted of comparing QRS areas during different ventricular activation patterns. The ratio of areas from the vector-cardiogram (VCG) and extensi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(76)80009-x
更新日期:1976-01-01 00:00:00
abstract::Controlled physical training has been shown to be a valuable therapeutic addition to a pharmacological treatment in patients with chronic heart failure (CHF). It is speculated that repeated physical training can improve the autonomic modulation of the cardiovascular system in patients with CHF. The present study evalu...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jelectrocard.2012.01.002
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:The use of vectorcardiography (VCG) has regained interest, however, original Frank-VCG equipment is rare. This study compares the measured VCGs with those synthesized from the 12-lead electrocardiogram (ECG) in patients with heart failure and conduction abnormalities, who are candidate for cardiac resynchron...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2015.04.001
更新日期:2015-07-01 00:00:00
abstract::We recently reported that signal averaged electrocardiograms (SAECG) measurements possess a circadian rhythm and are closely related to heart rate or heart rate variability in healthy volunteers. This study determines the influence of autonomic tone on the filtered QRS (f-QRS) duration from SAECG by using pharmacologi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(00)80096-5
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Interatrial block (IAB; P waves >/= 110 milliseconds), the conduction delay between the right (RA) and left atrium (LA), is depicted on the electrocardiogram (ECG) as prolonged, often bifid ("notched"), P waves with distinguishable RA and LA components. Although electrophysiologic (EP) studies give some insi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2005.11.002
更新日期:2006-10-01 00:00:00
abstract::We report a case of an outpatient cardiac arrest due to ventricular fibrillation and resuscitated with external automated defibrillator shocks in which acute amiodarone infusion unmasked a Brugada phenotype electrocardiographic pattern. Possible interferences by this drug and suitable therapeutic actions are discussed...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2012.02.005
更新日期:2012-07-01 00:00:00
abstract::The pathophysiological mechanisms of altered transmembrane potentials in diseased human atria were investigated in 20 patients who were divided into group A (normal) and group B (diseased). The electrophysiological data of right atrial tissues measured with glass microelectrodes included maximum diastolic potentials (...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(86)80006-1
更新日期:1986-01-01 00:00:00
abstract::Recent studies have shown that ventricular myocardium is composed of at least 3 electrophysiologically distinct cell types: epicardial, endocardial, and M cells. Action potentials recorded from epicardial and M cells, unlike those recorded from endocardium, display a spike-and-dome morphology, the result of a prominen...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/s0022-0736(99)90074-2
更新日期:1999-01-01 00:00:00
abstract:AIMS:The objective of the study was to develop normal limits of the ECG in an apparently healthy population of South Asians living in India. METHODS:Three centres contributed to recording 12 lead ECGs on identical digital electrocardiographs. Apparently healthy volunteers were recruited and ECGs were first transferred...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jelectrocard.2015.04.013
更新日期:2015-07-01 00:00:00
abstract::The Electrocardiogram has extensively been used for evaluation and triage of patients with acute chest pain. The clinician admitting a patient with ST elevation acute myocardial infarction should be able to estimate the size and location of the ischemic area at risk, how much of the ischemic myocardium has already und...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2005.01.003
更新日期:2005-04-01 00:00:00
abstract::Effects of pirmenol hydrochloride and lidocaine hydrochloride on intraventricular conduction were examined in the infarcted heart of anesthetized dogs. The effects of the drugs on the excitation induced by ventricular stimulations were determined with coupling intervals between 150 and 1,000 ms. Effects of the drugs o...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(91)90020-m
更新日期:1991-10-01 00:00:00
abstract::Hypertrophic cardiomyopathy (HCM) with apical aneurysm (AA) is rare, but has been reported to be associated with refractory ventricular tachycardias (VTs). Majority of such cases had a central isthmus of the reentry circuit on the border zone of AA. In this report, we describe a rare case of the successful epicardial ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2020.06.014
更新日期:2020-01-01 00:00:00
abstract::An analytical study was performed to estimate the magnitude of the visual Q wave duration bias produced by pressurized ink round stylus electrocardiographic (ECG) recorders. With a paper speed of 25 mm/sec and the ECG tracing width of 0.25 mm, the visually measured Q waves are on the average 8 msec too short. The corr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(78)80137-x
更新日期:1978-10-01 00:00:00
abstract:BACKGROUND:We studied whether social media applications can serve as effective educational tools for teaching electrocardiogram (ECG) interpretation to medical residents. METHODS:39 emergency, family, and internal medicine residents participated in the 33-week "ECG of the Week" curriculum via Facebook and Twitter. ECG...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2017.04.010
更新日期:2017-01-01 00:00:00
abstract::Information from 24-hour monitoring with on-line vectorcardiography, starting immediately after admission, was compared with results from a predischarge exercise test 3-13 days after admission. A total of 169 patients with acute myocardial infarction and 73 patients with unstable angina pectoris were investigated. Pat...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(05)80045-7
更新日期:1995-10-01 00:00:00
abstract::Syncope is a risk factor for sudden cardiac death (SCD) in many conditions associated with structural heart disease as well as inherited heart disease. The ECG in patients with syncope should be examined carefully for signs of structural heart disease, such as myocardial infarction or cardiomyopathy; signs of conducti...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2013.07.008
更新日期:2013-11-01 00:00:00
abstract::Electrocardiograms were taken from a 67-year-old man with 2:1 atrioventricular block in whom alternating reversed Wenckebach periodicity was found. Long PR intervals of alternately conducted P waves progressively shortened until an alternate P wave was blocked. After an alternate P wave was blocked, the next alternate...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2003.50010
更新日期:2003-01-01 00:00:00
abstract::Atrioventricular node reentry tachycardia is an incompletely understood substrate for supraventricular tachycardia. Although there is agreement that the mechanism involves functionally separate fast and slow AV node pathways, which are somewhat anatomically discrete, the anatomical basis for the reentrant circuit is n...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2008.06.016
更新日期:2008-11-01 00:00:00
abstract::A low-cost micro-processor combined with a standard 3-channel electrocardiographic recorder was adapted to polar coordinate conversion of Frank orthogonal lead signals and display of the resultant polarcardiogram. The processor also functions as a computer of average transients for the ECG complexes and provides autom...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(82)80047-2
更新日期:1982-01-01 00:00:00
abstract::Electrocardiographic manifestation mimicking the hyperacute phase of myocardial infarction and the electrical alternans of the elevated ST-segment in association with subarachnoid hemorrhage were reported in two patients with no evidence of heart disease. In both cases the ST-segment changes were transient and there w...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(89)90082-4
更新日期:1989-04-01 00:00:00
abstract::Hypertrophic cardiomyopathy (HCM) have been reported to display impaired heart rate variability, although little is known regarding its prognostic value. By using fast Fourier transformation of 24-hour Holter recordings in 73 HCM patients at a stable clinical condition, we computed 4 spectral components: very low freq...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2003.08.005
更新日期:2003-10-01 00:00:00
abstract::Traditional electrocardiographic (ECG) and vectorcardiographic (VCG) criteria for left ventricular enlargement (LVE) understandably emphasize the increased tendency of the maximal electrical forces of ventricular depolarization to be directed toward the left. This tendency is manifested on the ECG by increased amplitu...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::A 58-year-old woman with a history of multi-origin atrial tachycardia and limb-girdle muscular dystrophy was treated for presyncope caused by pauses in atrial rhythm. A dual-chamber pacemaker was implanted. The low-voltage area extended broadly, but 10-V pacing could not capture the large right atrium, including the r...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2020.05.003
更新日期:2020-01-01 00:00:00
abstract::In 37 consecutive patients with acute myocardial infarction undergoing Streptokinase infusion and acute coronary angiography, the electrocardiographic findings were compared with the findings during angiography. All 15 patients with an occluded right coronary artery demonstrated an electrocardiographic pattern of an a...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(84)80062-x
更新日期:1984-07-01 00:00:00
abstract:UNLABELLED:The verapamil-sensitive Belhassen tachycardia is a ventricular reentrant tachycardia, involving left-sided Purkinje fibers and abnormal Purkinje or myocardial tissue. Ablation is feasible, targeting a diastolic fascicular potential in the apical left ventricle. CASE REPORT:We report on a 13-year-old girl wi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2011.02.003
更新日期:2011-11-01 00:00:00
abstract::RBBB tachycardia with NW axis is considered to be VT unless proved otherwise. However underlying conduction system disease can produce electrocardiographic patterns suggestive of bundle branch block with extreme left axis which can cause difficulty in differentiating VT from SVT as in this case. ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2017.08.036
更新日期:2018-01-01 00:00:00
abstract::The present study describes the successful radiofrequency ablation of an uncommon type of A-V nodal tachycardia. Electroanatomical mapping of the right atria was used to locate the region of the earliest atrial activation and allowed for positioning of the ablation catheter and a successful 25-watt radiofrequency burn...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2002.29943
更新日期:2002-01-01 00:00:00