The dicyclohexylcarbodiimide-binding protein c of ATP synthase from Escherichia coli is not sufficient to express an efficient H+ conduction.

abstract：:The resonance Raman excitation profiles of a number of charge transfer transitions in electron donor/acceptor complexes with tetracyanoethylene as acceptor in solution at room temperature are reported and compared with absorption and fluorescence spectra of these complexes. All complexes show distinct anomalies which ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Michaelian KH,Rieckhoff KE,Voigt EM

更新日期：1975-11-01 00:00:00

abstract：:Reports differ as to whether reconstitution of telomerase activity alone is sufficient for immortalization of different types of human somatic cells or whether additional activities encoded by other "immortalizing" genes are also required. Here we show that ectopic expression of either the catalytic subunit of human t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： O'Hare MJ,Bond J,Clarke C,Takeuchi Y,Atherton AJ,Berry C,Moody J,Silver AR,Davies DC,Alsop AE,Neville AM,Jat PS

更新日期：2001-01-16 00:00:00

abstract：:The law of the iterated logarithm provides a family of bounds all of the same order such that with probability one only finitely many partial sums of a sequence of independent and identically distributed random variables exceed some members of the family, while for others infinitely many do so. In the former case, the...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Slivka J

更新日期：1969-06-01 00:00:00

abstract：:Lithium ion at concentrations between 2 and 20 mM simulated the stimulatory effects of insulin on the uptake of alpha-aminoisobutyric acid, synthesis of RNA and DNA, and cell multiplication in mouse mammary gland explants cultured in a chemically defined synthetic medium. Other monovalent cations were virtually ineffe...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hori C,Oka T

更新日期：1979-06-01 00:00:00

abstract：:Photosystem I (PSI) reaction centers (RCs) of the thermophilic cyanobacterium Mastigocladus laminosus were purified and characterized. The PSI RC was obtained in two forms, monomeric and trimeric. The two forms contained the same number of pigments per P700 and displayed similar photochemical activities. The two forms...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Almog O,Shoham G,Michaeli D,Nechushtai R

更新日期：1991-06-15 00:00:00

abstract：:14-3-3 proteins are ubiquitously expressed regulators of various cellular functions, including proliferation, metabolism, and differentiation, and altered 14-3-3 expression is associated with development and progression of cancer. We report a transforming 14-3-3 oncoprotein, which we identified through conventional cy...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lee CH,Ou WB,Mariño-Enriquez A,Zhu M,Mayeda M,Wang Y,Guo X,Brunner AL,Amant F,French CA,West RB,McAlpine JN,Gilks CB,Yaffe MB,Prentice LM,McPherson A,Jones SJ,Marra MA,Shah SP,van de Rijn M,Huntsman DG,Dal Cin P

更新日期：2012-01-17 00:00:00

abstract：:A membrane-associated folate binding protein (FBP) and a soluble FBP, which is released into the culture medium, have been purified from human KB cells using affinity chromatography. By NaDodSO4/PAGE, both proteins have an apparent Mr of approximately 42,000. However, in the presence of Triton X-100, the soluble FBP e...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Luhrs CA,Pitiranggon P,da Costa M,Rothenberg SP,Slomiany BL,Brink L,Tous GI,Stein S

更新日期：1987-09-01 00:00:00

abstract：:Albatrosses (Diomedeidae) do not occur in the North Atlantic Ocean today except as vagrants, although five species were present in the early Pliocene. No fossil breeding sites of albatrosses were known previously. The timing of extinction of albatrosses in the North Atlantic was likewise unknown. Deposits that formed ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Olson SL,Hearty PJ

更新日期：2003-10-28 00:00:00

abstract：:Many of the mutagenic or lethal effects of ionization radiation can be attributed to damage caused to the DNA by low-energy electrons. To gain insight on the parameters affecting this process, we measured the low-energy electron (<2 eV) transmission yield through self-assembled monolayers of short DNA oligomers. The e...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ray SG,Daube SS,Naaman R

更新日期：2005-01-04 00:00:00

abstract：:Tridecaptin A1 (TriA1) is a nonribosomal lipopeptide with selective antimicrobial activity against Gram-negative bacteria. Here we show that TriA1 exerts its bactericidal effect by binding to the bacterial cell-wall precursor lipid II on the inner membrane, disrupting the proton motive force. Biochemical and biophysic...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cochrane SA,Findlay B,Bakhtiary A,Acedo JZ,Rodriguez-Lopez EM,Mercier P,Vederas JC

更新日期：2016-10-11 00:00:00

abstract：:We have previously shown that lymphoblasts alloactivated in vitro acquire the capacity of stimulating the autologous mixed lymphocyte response. This response is anti-idiotypic in nature because lymphocytes so primed display accelerated memory responses only when restimulated by autologous lymphoblasts that have been a...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Suciu-Foca N,Reed E,Rohowsky C,Kung P,King DW

更新日期：1983-02-01 00:00:00

abstract：:Staphylococcus aureus is a leading cause of both nosocomial and community-acquired infection. Biofilm formation at the site of infection reduces antimicrobial susceptibility and can lead to chronic infection. During biofilm formation, a subset of cells liberate cytoplasmic proteins and DNA, which are repurposed to for...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： DeFrancesco AS,Masloboeva N,Syed AK,DeLoughery A,Bradshaw N,Li GW,Gilmore MS,Walker S,Losick R

更新日期：2017-07-18 00:00:00

abstract：:Ecosystem restoration aims to restore biodiversity and valuable functions that have been degraded or lost. The Coral Triangle is a hotspot for marine biodiversity held in its coral reefs, seagrass meadows, and mangrove forests, all of which are in global decline. These coastal ecosystems support valuable fisheries and...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Williams SL,Ambo-Rappe R,Sur C,Abbott JM,Limbong SR

更新日期：2017-11-07 00:00:00

abstract：:In vivo, G protein-coupled receptors (GPCR) for neurotransmitters undergo complex intracellular trafficking that contribute to regulate their abundance at the cell surface. Here, we report a previously undescribed alteration in the subcellular localization of D1 dopamine receptor (D1R) that occurs in vivo in striatal ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dumartin B,Jaber M,Gonon F,Caron MG,Giros B,Bloch B

更新日期：2000-02-15 00:00:00

abstract：:The use of carbon dioxide as a renewable and environmentally friendly source of carbon in organic synthesis is a highly attractive approach, but its real world applications remain a great challenge. The major obstacles for commercialization of most current protocols are their low catalytic performances, harsh reaction...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yu D,Zhang Y

更新日期：2010-11-23 00:00:00

abstract：:Inosine monophosphate dehydrogenase (IMPDH) controls a key metabolic step in the regulation of cell growth and differentiation. This step is the NAD-dependent oxidation of inosine 5' monophosphate (IMP) to xanthosine 5' monophosphate, the rate-limiting step in the synthesis of the guanine nucleotides. Two isoforms of ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Colby TD,Vanderveen K,Strickler MD,Markham GD,Goldstein BM

更新日期：1999-03-30 00:00:00

abstract：:The floating water bridge phenomenon is a freestanding rope-shaped connection of pure liquid water, formed under the influence of a high potential difference (approximately 15 kV). Several recent spectroscopic, optical, and neutron scattering studies have suggested that the origin of the bridge is associated with the ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Skinner LB,Benmore CJ,Shyam B,Weber JK,Parise JB

更新日期：2012-10-09 00:00:00

abstract：:Vibrio cholerae O1 exists as two major serotypes, Inaba and Ogawa, which are associated with the O antigen of the lipopolysaccharide and are capable of unequal reciprocal interconversion. The 20-kilobase rfb regions encoding O-antigen biosynthesis in strains 569B (Inaba) and O17 (Ogawa) have been cloned in Escherichia...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Stroeher UH,Karageorgos LE,Morona R,Manning PA

更新日期：1992-04-01 00:00:00

abstract：:Addition of Na+ to Na+-depleted Swiss 3T3 cells causes a rapid and dramatic increase in intracellular pH, as monitored by uptake of the weak acid 5,5-dimethyloxazolidine-2,4-dione. The effect of Na+ is concentration dependent (half-maximal effect at 38 mM); this cation can be replaced by Li+ but not by K+ or the choli...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schuldiner S,Rozengurt E

更新日期：1982-12-01 00:00:00

abstract：:Analysis of commercial catches reveals a serial depletion of some oceanic fish stocks over time, resulting in fisheries focusing on increasingly smaller species closer to the base of the food chain. This effect, described as fishing down the marine food web, is observed when the trophic level of the catch declines ove...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dunlop ES,Goto D,Jackson DA

更新日期：2019-10-01 00:00:00

abstract：:In the basal ganglia, inputs from the nucleus accumbens (NAc) are transmitted through both direct and indirect pathways and control reward-based learning. In the NAc, dopamine (DA) serves as a key neurotransmitter, modulating these two parallel pathways. This study explored how reward learning and its flexibility are ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yawata S,Yamaguchi T,Danjo T,Hikida T,Nakanishi S

更新日期：2012-07-31 00:00:00

abstract：:For species to stay temporally tuned to their environment, they use cues such as the accumulation of degree-days. The relationships between the timing of a phenological event in a population and its environmental cue can be described by a population-level reaction norm. Variation in reaction norms along environmental ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Delgado MDM,Roslin T,Tikhonov G,Meyke E,Lo C,Gurarie E,Abadonova M,Abduraimov O,Adrianova O,Akimova T,Akkiev M,Ananin A,Andreeva E,Andriychuk N,Antipin M,Arzamascev K,Babina S,Babushkin M,Bakin O,Barabancova A,Bas

更新日期：2020-12-08 00:00:00

abstract：:The alternative adaptive immune system of jawless vertebrates is based on different isotypes of variable lymphocyte receptors (VLRs) that are composed of leucine-rich repeats (LRRs) and expressed by distinct B- and T-like lymphocyte lineages. VLRB is expressed by B-like cells, whereas VLRA and VLRC are expressed by tw...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Holland SJ,Gao M,Hirano M,Iyer LM,Luo M,Schorpp M,Cooper MD,Aravind L,Mariuzza RA,Boehm T

更新日期：2014-10-14 00:00:00

abstract：:A promising strategy for DNA sequencing exploits transposons to provide mobile sites for the binding of sequencing primers. For such a strategy to be maximally efficient, the location and orientation of the transposon must be readily determined and the insertion sites should be randomly distributed. We demonstrate an ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Strausbaugh LD,Bourke MT,Sommer MT,Coon ME,Berg CM

更新日期：1990-08-01 00:00:00

abstract：:In order to study the mutagenic effects of site-specific, covalent modifications of biologically active DNA, we need host cells that are permissive for any type of mutation that might be produced in vivo from the modified DNA. Specifically, we require a general, in vivo complementation system for the bacteriophage phi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Humayun MZ,Chambers RW

更新日期：1978-02-01 00:00:00

abstract：:Dopamine is believed to contribute to the degeneration of dopamine-containing neurons in the brain. However, whether dopamine affects the survival of other neuronal populations has remained unclear. Here we document that mice with persistently elevated extracellular dopamine, resulting from inactivation of the dopamin...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cyr M,Beaulieu JM,Laakso A,Sotnikova TD,Yao WD,Bohn LM,Gainetdinov RR,Caron MG

更新日期：2003-09-16 00:00:00

abstract：:Elastogenesis is a hierarchical process by which cells form functional elastic fibers, providing elasticity and the ability to regulate growth factor bioavailability in tissues, including blood vessels, lung, and skin. This process requires accessory proteins, including fibulin-4 and -5, and latent TGF binding protein...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kumra H,Nelea V,Hakami H,Pagliuzza A,Djokic J,Xu J,Yanagisawa H,Reinhardt DP

更新日期：2019-10-08 00:00:00

abstract：:Recent studies investigating the relationship between crop genetic diversity and human cultural diversity patterns showed that seed exchanges are embedded in farmers' social organization. However, our understanding of the social processes involved remains limited. We investigated how farmers' membership in three major...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Labeyrie V,Thomas M,Muthamia ZK,Leclerc C

更新日期：2016-01-05 00:00:00

abstract：:Stroke patients with small central nervous system infarcts often demonstrate an acute dysexecutive syndrome characterized by difficulty with attention, concentration, and processing speed, independent of lesion size or location. We use magnetoencephalography (MEG) to show that disruption of network dynamics may be res...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Marsh EB,Brodbeck C,Llinas RH,Mallick D,Kulasingham JP,Simon JZ,Llinás RR

更新日期：2020-12-29 00:00:00

abstract：:In layered materials, a common mode of deformation involves buckling of the layers under tensile deformation in the direction perpendicular to the layers. The instability mechanism, which operates in elastic materials from geological to nanometer scales, involves the elastic contrast between different layers. In a reg...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Makke A,Perez M,Lame O,Barrat JL

更新日期：2012-01-17 00:00:00