Effects of Mg2+ and adenine nucleotides on thymidylate synthetase from different mouse tumors.

abstract：:Plant cells contain lipid-transfer proteins (LTPs) able to transfer phospholipids between membranes in vitro. Plant LTPs share in common structural and functional features. Recent structural studies carried out by NMR and X-ray crystallography on an LTP isolated from maize seeds have showed that this protein involves ...

journal_title：Molecular and cellular biochemistry

authors： Guerbette F,Grosbois M,Jolliot-Croquin A,Kader JC,Zachowski A

更新日期：1999-02-01 00:00:00

abstract：:The effect of beta-alanyl-L-histidinato zinc (AHZ) on protein components in osteoblastic MC3T3-E1 cells was investigated. Cells were cultured for 3 days at 37 degrees C in CO2 incubator in plastic dishes containing alpha-modified minimum essential medium supplemented with 10% fetal bovine serum. After the cultures, th...

journal_title：Molecular and cellular biochemistry

authors： Yamaguchi M,Hashizume M

更新日期：1994-07-27 00:00:00

abstract：:Genetic adaptation is one of the key features of Escherichia coli (E. coli) that ensure its survival in different hostile environments. E. coli seems to initiate biofilm development in response to specific environmental cues. A number of properties inherent within bacterial biofilms indicate that their gene expression...

journal_title：Molecular and cellular biochemistry

authors： Adnan M,Morton G,Hadi S

更新日期：2011-11-01 00:00:00

abstract：:In this study, the effect of (Boc-Lys (Boc)-Arg-Asp-Ser (tBu)-OtBu), a tetrapeptide derivative (PEP1261) was examined for antiproliferative potency and apoptotic induction. Synovial fibroblasts were isolated from collagen-induced arthritic (CIA) rats and exposed to peptides viz., PEP1261, and parental peptides (KRDS a...

journal_title：Molecular and cellular biochemistry

authors： Kumar DA,Settu K,Raju KV,Kumanan K,Manohar BM,Puvanakrishnan R

更新日期：2006-01-01 00:00:00

abstract：:In this paper we review some of the large quantities of information currently available concerning the identification, structure and function of Ca(2+)-binding proteins of endoplasmic and sarcoplasmic reticulum membranes. The review places particular emphasis on identification and discussion of Ca2+ 'storage' proteins...

journal_title：Molecular and cellular biochemistry

authors： Milner RE,Famulski KS,Michalak M

更新日期：1992-05-13 00:00:00

abstract：:The accessibility of pyridoxal 5'-phosphates of the phosphorylase ab hybrid to resolution by imidazole citrate and cysteine was studied and compared with that of the b and a forms. Promotion of resolution of phosphorylated forms by raising the temperature or in the presence of glycogen indicates that the resistance of...

journal_title：Molecular and cellular biochemistry

authors： Vereb G,Pallagi E,Gergely P

更新日期：1992-03-25 00:00:00

abstract：:1. Glucokinase is one of four glucose phosphorylating enzymes present in rat liver. Its distinctive features are a high K-m for glucose (high-K-m isozyme) and a rather narrow substrate specificity. In contrast, the other three enzymes, collectively called hexokinases or low-K-m isozymes, exhibit low K-m values for glu...

journal_title：Molecular and cellular biochemistry

authors： Niemeyer H,Ureta T,Clark-Turri L

更新日期：1975-02-28 00:00:00

abstract：:Respiratory muscle injury may result from excessive loading due to a decrease in respiratory muscle strength, an increase in the work of breathing, or an increase in the rate of ventilation. Other conditions such as hypoxemia, hypercapnia, aging, decreased nutrition, and immobilization may potentiate respiratory muscl...

journal_title：Molecular and cellular biochemistry

authors： Reid WD,MacGowan NA

更新日期：1998-02-01 00:00:00

abstract：:Treatment of bovine pulmonary artery smooth muscle cells with endothelin-1 (ET-1) caused an increase in the expression and activation of proMMP-2 in the cells. The present study was undertaken to determine the underlying mechanisms involved in this scenario. We demonstrated that (i) pretreatment with NADPH oxidase inh...

journal_title：Molecular and cellular biochemistry

authors： Sarkar J,Chowdhury A,Chakraborti T,Chakraborti S

更新日期：2016-04-01 00:00:00

abstract：:Lens epithelial cells are the metabolic unit of the lens and antioxidant enzymes are mainly concentrated here. The purpose of this study was to maintain human lens epithelial cells (HLEC) in culture and examine the status of antioxidant enzymes (glutathione peroxidase (GSHPx), catalase (CAT), glutathione-S-transferase...

journal_title：Molecular and cellular biochemistry

authors： Mohanty I,Joshi S,Trivedi D,Srivastava S,Tandon R,Gupta SK

更新日期：2002-09-01 00:00:00

abstract：:The conserved N-domain of the STAT proteins has been implicated in several activities crucial to cytokine signaling including receptor recruitment and STAT activation, cooperative DNA binding and STAT-dependent gene expression. We evaluated the role of the STAT3 N-domain in the IL-6 signal transduction pathway leading...

journal_title：Molecular and cellular biochemistry

authors： Zhang L,Badgwell DB,Bevers JJ 3rd,Schlessinger K,Murray PJ,Levy DE,Watowich SS

更新日期：2006-08-01 00:00:00

abstract：:Twenty-six days of fat deficiency brought about a decrease of linoleic and an increase of oleic acid in rough endoplasmic reticulum (RER) of guinea pig liver. Arachidonic acid was only slightly decreased in some phospholipids whereas eicose-5,8,11-trienoic acid was not enhanced except in phosphatidyl-inositol. All the...

journal_title：Molecular and cellular biochemistry

authors： Soulages JL,Brenner RR

更新日期：1987-12-01 00:00:00

abstract：:Modulation of Ca(2+) homoeostasis in cardiac myocytes plays a major role in beat-to-beat regulation of heart function. Previous studies suggest that sphingosine-1-phosphate (S1P), a biologically active sphingomyelin metabolite, regulates Ca(2+) handling in cardiac myocytes, but the underlying mechanism is unclear. In ...

journal_title：Molecular and cellular biochemistry

authors： Egom EE,Bae JS,Capel R,Richards M,Ke Y,Pharithi RB,Maher V,Kruzliak P,Lei M

更新日期：2016-08-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are known as crucial regulators in the development of OC. In the current study, we aim to explore the function and molecular mechanism of lncRNA DLEU1 in OC. Quantitative real-time polymerase chain reaction (qRT-PCR) was applied to determine the expression of DLEU1, miR-429, and TFAP2A i...

journal_title：Molecular and cellular biochemistry

authors： Xu H,Wang L,Jiang X

更新日期：2020-11-10 00:00:00

abstract：:The present study was attempted to identify transcriptionally regulated genes of the normal neurocytes responsive to iron availability. Postnatal rat hippocampus cells were primarily cultured either under the iron-loaded or depleted conditions. These cultured cells were applied for the generation of subtracted complem...

journal_title：Molecular and cellular biochemistry

authors： Liu M,Xiao DS,Qian ZM

更新日期：2007-06-01 00:00:00

abstract：:Protein carbonyls are formed as a consequence of the oxidative modification of proteins by reactive oxygen species and are commonly used as a marker of protein oxidation in cells and tissues. Melatonin has free radical scavenging ability besides its classical role as a hormonal signaling agent. Curcumin, a phytochemic...

journal_title：Molecular and cellular biochemistry

authors： Dkhar P,Sharma R

更新日期：2013-08-01 00:00:00

abstract：:Abnormal angiogenesis underlies many pathological conditions and is critical for the growth and maintenance of various types of tumors, including hormone-dependent cancers. Since estrogens are potent carcinogens in humans and rodents, and are involved in regulating angiogenesis, this study was designed to examine the ...

journal_title：Molecular and cellular biochemistry

authors： Banerjee SK,Campbell DR,Weston AP,Banerjee DK

更新日期：1997-12-01 00:00:00

abstract：:An increasing amount of experimental and epidemiological evidence implicates the involvement of oxygen derived radicals in the pathogenesis of cancer development. It is well known that chemical carcinogenesis is multistage process. Free radicals arefound to be involved in both initiation and promotion of multistage ca...

journal_title：Molecular and cellular biochemistry

authors： Perumal SS,Shanthi P,Sachdanandam P

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:We reported that urinary L-FABP reflected the progression of chronic kidney disease (CKD). This study is aimed to evaluate the clinical significance of urinary liver type fatty acid binding protein (L-FABP) as a biomarker for monitoring CKD. METHODS:Urinary L-FABP was measured using human L-FABP ELISA kit (...

journal_title：Molecular and cellular biochemistry

authors： Kamijo A,Sugaya T,Hikawa A,Yamanouchi M,Hirata Y,Ishimitsu T,Numabe A,Takagi M,Hayakawa H,Tabei F,Sugimoto T,Mise N,Omata M,Kimura K

更新日期：2006-03-01 00:00:00

abstract：:Liver glucose 6-phosphate dehydrogenase and phosphogluconate dehydrogenase activities were significantly decreased in both diabetic and fasted rats. Treatment of diabetic rats with insulin resulted in liver glucose 6-phosphate dehydrogenase and phosphogluconate dehydrogenase activities that were significantly greater ...

journal_title：Molecular and cellular biochemistry

authors： Martins RN,Stokes GB,Masters CL

更新日期：1986-05-01 00:00:00

abstract：:Idiopathic pes equinovarus is a congenital deformity of the foot and lower leg defined as a fixation of the foot in adduction, supination, and varus. Although the pathogenesis of clubfoot remains unclear, it has been suggested that fibroblasts and growth factors are involved. To directly analyze the protein compositio...

journal_title：Molecular and cellular biochemistry

authors： Ošt'ádal M,Eckhardt A,Herget J,Mikšík I,Dungl P,Chomiak J,Frydrychová M,Burian M

更新日期：2015-03-01 00:00:00

abstract：:Lipoamidase is found to be able to release various membrane-anchored enzymes from the membrane compartment of pig brain. Released enzymes revealed their intact enzyme activities in the soluble fraction. Lipoamidase could release at least two types of anchored enzymes, i.e. glycosyl-phosphatidylinositol-bonded and myri...

journal_title：Molecular and cellular biochemistry

authors： Oizumi J,Hayakawa K

更新日期：1992-09-22 00:00:00

abstract：:A matricellular protein, osteopontin (OPN), is expressed in response to mechanical stress and similar stimuli in the heart, integrates the inter-ECM signal transduction network of component cells, and maintains efficient contractility through quantitative and qualitative control of extracellular matrix (ECM) proteins....

journal_title：Molecular and cellular biochemistry

authors： Okamoto H

更新日期：2007-06-01 00:00:00

abstract：:A noncholinergic nicotine receptor on human phagocytic leukocytes has been characterized using the binding of 3H-(d,1)-nicotine. The average affinity +/- standard deviation of (d,1)-nicotine for the receptor on neutrophils is 36 +/- 18 nM (n = 6). The binding is saturable with an average of 8.7 x 10(4) sites per neutr...

journal_title：Molecular and cellular biochemistry

authors： Davies BD,Hoss W,Lin JP,Lionetti F

更新日期：1982-04-16 00:00:00

abstract：:A preparation of UDP-GalNAc:sialosyl lactosylceramide N-acetylgalactosaminyl transferase (E.C. 2.4.1.92) obtained from 14-day chick embryo brain was delipidated partially by treatment with cold acetone in the presence of varying amounts of sodium dodecyl sulphate (SDS). The lipid content and the enzyme activity of the...

journal_title：Molecular and cellular biochemistry

authors： Cortassa S,Maccioni HJ

更新日期：1989-01-23 00:00:00

abstract：:Purified mitochondria from rat liver were found to contain protein synthesis inhibitors, that could be extracted by disruption of mitochondrial membranes and fractionated by gel filtration into two fractions of low and high molecular weight. Small size inhibitors were also released from the latter peak by high ionic s...

journal_title：Molecular and cellular biochemistry

authors： Pérez JL,Dorta B,González-Cadavid N

更新日期：1984-06-01 00:00:00

abstract：:Glycyrrhizin, a major constituent of licorice (Glycyrrhiza glabra) root, has been reported to ameliorate insulin resistance, hyperglycemia, dyslipidemia, and obesity in rats with metabolic syndrome. Liver dysfunction is associated with this syndrome. The objective of this study is to investigate the effect of glycyrrh...

journal_title：Molecular and cellular biochemistry

authors： Sil R,Ray D,Chakraborti AS

更新日期：2015-11-01 00:00:00

abstract：:The levels of plasma apolipoprotein (apo) E, an anti-atherogenic protein involved in mammalian cholesterol transport, were found to be 2-3 fold lower in mice over-expressing human apoA-I gene. ApoE is mainly associated with VLDL and HDL-size particles, but in mice the majority of the apoE is associated with the HDL pa...

journal_title：Molecular and cellular biochemistry

authors： Srivastava RA

更新日期：2000-06-01 00:00:00

abstract：:To explore the effect of LYRM1 over-expression on basal and insulin-stimulated glucose uptake in rat skeletal muscle cells, and to understand the underlying mechanisms, Rat myoblasts (L6) transfected with either an empty expression vector (pcDNA3.1Myc/His B) or a LYRM1 expression vector were differentiated into myotub...

journal_title：Molecular and cellular biochemistry

authors： Kou C,Cao X,Qin D,Ji C,Zhu J,Zhang C,Zhu C,Gao C,Chen R,Guo X,Zhang M

更新日期：2011-02-01 00:00:00

abstract：:The effects of transcription and translation inhibitors on NADP-glutamate dehydrogenase and glutamine synthetase synthesis in nitrogen-starving Ankistrodesmus braunii cells have been studied. Considering the results obtained one can suggest that both enzymes are coded in a chloroplast genome and that during nitrogen s...

journal_title：Molecular and cellular biochemistry

authors： Shatilov VR,Sof'in AV,Zabrodina TM,Kretovich WL

更新日期：1982-09-03 00:00:00