Abstract：
:Ribonucleic acid (immune RNA, iRNA), extracted from the spleens of mice immunized with sheep red blood cells (SRBC), induced specific immunological memory. The humoral immune responses of iRNA-treated animals were compared with in vivo and in vitro primary and secondary responses, using the haemolytic plaque-forming cell (PFC) assay. IgM antibody formation was markedly higher in iRNA-treated than in any other mice. The effect of iRNA was antigen-specific and similar materials from non-immunized mice had no activity.
journal_name
Immunologyjournal_title
Immunologyauthors
Kodama K,Yoshida T,Shibiya T,Kurashige S,Mitsuhashi Ssubject
Has Abstractpub_date
1981-11-01 00:00:00pages
535-42issue
3eissn
0019-2805issn
1365-2567journal_volume
44pub_type
杂志文章相关文献
IMMUNOLOGY文献大全abstract：:The relationship between the IgA antibody response in serum (total and polymeric IgA) and intestinal secretions was examined in volunteers subjected to oral and parenteral typhoid vaccination. After oral vaccination (three doses of 10(11) live Ty21a vaccine given at 48-hr intervals), serum pIgA antibody to typhoid lip...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:Over the past years, increasing numbers of distinct subsets have been discovered and identified for a T lymphocytes' entity. Differentiation and function of each T cell subset are controlled by a specific master transcription factor. Importantly, Runt-related transcription factors, particularly Runx1 and Runx3, interp...
journal_title：Immunology
pub_type： 杂志文章,评审
doi：10.1111/j.1365-2567.2010.03381.x
更新日期：2011-02-01 00:00:00
abstract：:The experiments described in this paper have examined the migration of three fluorochrome-labelled T-lymphocyte subsets (CD4+, CD8+ and gamma delta+T19+) on a single passage from blood to lymph, through prescapular lymph nodes. Lymphocytes obtained from prescapular efferent lymph were labelled in vitro with fluorochro...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Various strains of anaerobic coryneforms and the closely related Propionibacteria have been compared in vivo with respect to their anti-tumour activity. Their effectiveness has been correlated with their serological relationship and to some extent with their ability to stimulate the lymphoreticular system. Organisms b...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:Culture dishes precoated with thin layers of acid soluble rat tail collagen simplify conditions necessary to obtain in vitro high IgG anti-DNP responses from primed and boosted mice. In contrast to Mishell-Dutton type cultures the use of collagen precludes the need to continually rock cultures and to add nutrients. Re...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：:Bovine respiratory syncytial virus (RSV) is a major cause of respiratory disease in young calves. Recent studies in calves, in which different T-cell subsets were depleted, have shown that CD8+ T cells play a central role in recovery from RSV infection. The present study demonstrates that RSV-specific, major histocomp...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.1996.d01-667.x
更新日期：1996-07-01 00:00:00
abstract：:The hepatic and splenic uptake of circulating, small-latticed immune complexes and the effect of these complexes on the hepatic mononuclear phagocyte system (MPS) were examined in mice. The small-latticed immune complexes were prepared at fifty-fold antigen excess. The clearance from circulation and uptake by the live...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:Pre-exposure to bacterial lipopolysaccharide (LPS) or certain cytokines is known to enhance the ability of murine macrophages to generate a respiratory burst in response to subsequent stimulation, a phenomenon referred to as 'priming'. We report here that the cytokine interleukin-4 (IL-4) can prime murine macrophages....
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
abstract：:The role of major histocompatibility complex (MHC) and adhesion molecule expression by alveolar epithelium on the modulation of immune responses in the lung is not understood. We have developed efficient methods to isolate, purify and culture human alveolar epithelial cells (type II pneumocytes) in vitro. The expressi...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:Polysorbate 80 (PS80 or Tween-80) is often used as an additive to promote the rapid solubilization of pharmaceuticals in aqueous solutions. We investigated whether coinjection of a minimal amount of PS80 had a modulatory effect on the immunotherapeutic effects of Cry (Cryptomeria)-consensus peptide, a novel peptide de...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1111/j.1365-2567.2006.02390.x
更新日期：2006-07-01 00:00:00
abstract：:Adoptive transfer of anti-Listeria resistance by Listeria-immune spleen T cells was markedly reduced by pretreatment of the cells with monoclonal anti-Lyt 2.2 and complement (Lyt 2+C); pretreatment of cells with monoclonal anti-L3T4 and complement (L3T4+C) had a lesser effect on their ability to transfer resistance. L...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：:We describe a high-throughput screening system to detect interactions between leucocyte surface proteins, taking into account that these interactions are usually of very low affinity. The method involves producing the extracellular regions of leucocyte proteins with tags so that they can be bound to nanoparticles to p...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1111/j.1365-2567.2009.03153.x
更新日期：2010-01-01 00:00:00
abstract：:We have isolated, characterized and quantified the immunocompetent cells present in the extravascular hepatic compartment at various stages after Plasmodium yoelii malaria infection with sporozoites. Cytological analyses revealed a predominantly lymphoid population. In mice with a primary infection, the predominant ce...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:Plasma fibronectin (FN) has been demonstrated to serve as an opsonin involved in the ingestion of foreign particles by phagocytes. This study concerns the effect of FN exposure on the respiratory burst of normal human peripheral phagocytes, using a luminol-dependent chemiluminescence (CL) assay for measurement of reac...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:A murine model was used to study the respective roles of L3T4+ and Lyt-2+ T cells in protection against Chlamydia psittaci. Donor mice were intravenously (i.v.) infected with 1 x 10(5) plaque-forming units (PFU) per mice of live C. psittaci. One month after inoculation, splenic cells from donors were transferred into ...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Urokinase-type plasminogen activator (u-PA), tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 (IL-1) activities were measured for highly purified human monocytes cultured for 18 hr with recombinant human interleukin-3 (IL-3). IL-3 alone stimulated monocyte u-PA activity, but not TNF-alpha or IL-1 activity. H...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：:Various strains of the murine mycoplasma M. neurolyticum have been shown to induce extensive blast transformation of mouse lymphocytes, comparable in strength to mitogenicity exerted by these mycoplasma species on rat lymphocytes. The data summarized in this report demonstrate that this mitogenic effect is non-specifi...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1978-04-01 00:00:00
abstract：:Both lipopolysaccharide (LPS) and phorbol 12-myristate 13-acetate (PMA) impeded monocyte to macrophage differentiation with respect to typical phenotypic modulation and certain phagocyte-related processes. The down-regulation of the porcine monocyte marker SWC1, and up-regulation of the SWC9 macrophage marker were ret...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.2001.01266.x
更新日期：2001-08-01 00:00:00
abstract：:Group 2 innate lymphoid cells (ILC2s) are an important component of the innate immune system that execute important effector functions at barrier surfaces, such as lung and skin. Like T helper type 2 cells, ILC2s are able to release high amounts of type 2 cytokines that are essential in inducing allergic inflammation ...
journal_title：Immunology
pub_type： 杂志文章,评审
doi：10.1111/imm.13232
更新日期：2020-09-01 00:00:00
abstract：:A model of immediate-type hypersensitivity (ITH) in the dog using keyhole limpet haemocyanin (KLH) as the antigen was studied. Long-lasting ITH was induced in fifteen of sixteen dogs by the i.v. (Kepron & Tse, 1975), intradermal (Rockey, Schwartzmann & Halliwell, 1971), inhalation (Patterson & Kelley, 1974) and i.d. p...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:In this paper we report that treatment with 17 beta-oestradiol depresses cutaneous delayed-type hypersensitivity (DTH) to oxazolone (OXA) in female oophorectomized NZB/W mice. Analysis of the parental strains revealed that this oestrogen-induced inhibition of DTH mice is a trait inherited from the healthy NZW and not ...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Mice injected with rat erythrocytes developed anti-erythrocyte autoantibodies which reached a plateau at 4-12 weeks, then gradually declined until at about 24 weeks the majority of mice were negative. In such recovered mice re-challenge with rat erythrocytes produced an accelerated peak of autoantibody and a much more...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1980-04-01 00:00:00
abstract：:It has previously been shown in mice that activated peritoneal macrophages, when first removed from the peritoneal cavity, suppress mitogen-stimulated lymphocyte transformation in vitro as measured by [3H]-thymidine incorporation. In this study, it is demonstrated that activated macrophages that have been incubated al...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:The subcutaneous (s.c.) injection of sheep red blood cells (SRBC) without adjuvant into mice preferentially induced delayed hypersensitivity (DH) reaction, as measured by footpad swelling, while intraperitoneal (i.p.) measured by the haemagglutinin test. Under these conditions, the properties of the helper activities...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1975-05-01 00:00:00
abstract：:The cellular prion protein (PrPc) is a glycosyl-phosphatidylinositol (GPI)-linked cell surface protein, which is expressed at high density on nervous tissues and at lower levels on most other solid-organ tissues. It is also expressed on peripheral blood mononuclear cells (PBMC) of all lineages. In lymphocytes, its lev...
journal_title：Immunology
pub_type： 杂志文章
doi：10.1046/j.1365-2567.2001.01166.x
更新日期：2001-02-01 00:00:00
abstract：:In our efforts to identify products that might be used for active immunotherapy in human immunodeficiency virus (HIV) infection, we have studied synthetic peptides derived from the CD4 attachment site of gp120. Two peptides have emerged with particularly interesting properties. The first (B138) is linear and spans the...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:Preparations of ECF-A derived from anaphylactic guinea-pig lung diffusates were subjected to a variety of enzymatic degradations. The enzymes employed had specificityonly for their appropiate subtstates. No effect was found following treatmentwith relatively high doses of trypsin, alpha-chymotrypsin, pronase, alkali...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1975-04-01 00:00:00
abstract：:Expression of Fc gamma receptors on human placental trophoblast was investigated by immunostaining and immunoblotting using a panel of Fc gamma receptor monoclonal antibodies (mAb). Fc gamma receptors typical of other cell types were not detected on syncytiotrophoblast in term placentae when transplacental IgG transpo...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:The immunosuppressive effect of cyclosporin A (CS-A) was investigated in RIC-Sprague-Dawley rats. In vivo, CS-A totally abolished the formation of antibodies to the hapten dinitrophenyl (DNP) in rats immunized with DNP-keyhole limpet haemocyanin. In vitro, the effect of CS-A was investigated in spleen cell cultures st...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：:Exposure of thioglycollate-elicited murine peritoneal macrophages to wheat germ agglutinin (WGA) increased markedly the uptake of six different bacteria, which have surface receptors for the lectin. Uptake of Staphylococcus aureus H was higher by 3-5-fold, of S. aureus 52A2 by 1.8-fold, of S. aureus 52A5 by 1.7-fold, ...
journal_title：Immunology
pub_type： 杂志文章
doi：
更新日期：1984-08-01 00:00:00
