Abstract：
:Ten mutations are described that transform genotypic hermaphrodites of the nematode Caenorhabditis elegans into phenotypic males. These fall into three autosomal complementation groups, termed tra-1, tra-2, and tra-3. Two alleles of tra-1 produce almost complete transformation, to a fertile male phenotype; such transformed animals are useful for analyzing sex-linked genes. All alleles of tra-1 and tra-2 are recessive; the one known allele of tra-3 is both recessive and maternal in effect. Where tested, both XX and XXX hermaphrodites are transformed into males, but XO males (true males) are unaffected by these mutations. It is suggested that these genes are actually involved in hermaphrodite development and have no role in male development.
journal_name
Geneticsjournal_title
Geneticsauthors
Hodgkin JA,Brenner Ssubject
Has Abstractpub_date
1977-06-01 00:00:00pages
275-87issue
2 Pt. 1eissn
0016-6731issn
1943-2631journal_volume
86pub_type
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