Biliary lipid output and bile acid kinetics in cholesterol gallstone disease. Evidence for an increased hepatic secretion of cholesterol in Swedish patients.

abstract：:A case of acute bacterial endocarditis is presented in which gallbladder infarction and areas of hepatic infarction were documented. Selective angiography showed findings consistent with emboli to the gallbladder and hepatic circulations. ...

journal_title：Gastroenterology

authors： Henrich WL,Huehnegarth RJ,Rösch J,Melnyk CS

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND & AIMS:Although a significant amount of regenerating gene (REG) Ialpha protein is present not only in normal gastric mucosa but also in gastric cancer tissues, its pathophysiologic role in gastric cancer development remains unclear. We investigated REG Ialpha protein expression in early gastric cancers, and ...

journal_title：Gastroenterology

authors： Sekikawa A,Fukui H,Fujii S,Takeda J,Nanakin A,Hisatsune H,Seno H,Takasawa S,Okamoto H,Fujimori T,Chiba T

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:To date, the potential effects of free radicals on the activities of intestinal brush-border membrane enzymes have received little attention. Therefore, we conducted a series of experiments to examine the effects of free radicals on various enzymatic activities of rat small intestinal brush-border membranes....

journal_title：Gastroenterology

authors： Dudeja PK,Brasitus TA

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND & AIMS:We assessed the association of body mass and gastric volumes (fasting and postprandial) with satiation and postprandial symptoms. METHODS:Healthy obese and nonobese subjects underwent measurement of caloric intake at maximum satiation; postprandial symptoms were measured with visual analogue scales 3...

journal_title：Gastroenterology

authors： Delgado-Aros S,Cremonini F,Castillo JE,Chial HJ,Burton DD,Ferber I,Camilleri M

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND AIMS:It is not clear what induction dose of mesalamine is optimal for treating patients with mildly and moderately active ulcerative colitis (UC). This study was conducted to determine the efficacy and safety of mesalamine 4.8 g/day compared with 2.4 g/day for the treatment of moderately active UC. METH...

journal_title：Gastroenterology

authors： Sandborn WJ,Regula J,Feagan BG,Belousova E,Jojic N,Lukas M,Yacyshyn B,Krzeski P,Yeh CH,Messer CA,Hanauer SB

更新日期：2009-12-01 00:00:00

abstract：:Caliber-persistent artery of the stomach (also known as cirsoid aneurysm, Dieulafoy's lesion, and submucosal arterial malformation) is clinically manifested as recurrent, massive, often fatal hematemesis. The lesion often is not seen endoscopically. Left gastric angiography in one patient with hematemesis showed a con...

journal_title：Gastroenterology

authors： Eidus LB,Rasuli P,Manion D,Heringer R

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND & AIMS:We have shown that addition of gum arabic (GA) to a 90 mmol/L sodium-111 mmol/L glucose oral rehydration solution (ORS) enhances its effectiveness for water and electrolyte absorption in normal rats. The present study extends these observations on GA in ORS to two rat models of diarrheal disease. MET...

journal_title：Gastroenterology

authors： Wapnir RA,Wingertzahn MA,Moyse J,Teichberg S

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND & AIMS:We previously demonstrated that the 2 APC mutations in human colorectal tumors are coselected, because tumorigenesis requires an optimal level of Wnt signaling. We and others subsequently showed that the truncated APC proteins in colorectal tumors usually retain a total of 1-2 beta-catenin binding/deg...

journal_title：Gastroenterology

authors： Pollard P,Deheragoda M,Segditsas S,Lewis A,Rowan A,Howarth K,Willis L,Nye E,McCart A,Mandir N,Silver A,Goodlad R,Stamp G,Cockman M,East P,Spencer-Dene B,Poulsom R,Wright N,Tomlinson I

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND & AIMS:Long-term ursodeoxycholic acid (UDCA) therapy slows the progression of primary biliary cirrhosis. This study examined the effect of UDCA therapy on survival free of liver transplantation in a large group of patients. METHODS:Data from three clinical trials were combined in which patients with primary...

journal_title：Gastroenterology

authors： Poupon RE,Lindor KD,Cauch-Dudek K,Dickson ER,Poupon R,Heathcote EJ

更新日期：1997-09-01 00:00:00

abstract：:Excretion of hydrogen in breath commonly persists despite an overnight fast. Although elevation of hydrogen concentration above the fasting value after administration of a test sugar is evidence of malabsorption, the significance of the fasting value itself is unknown. We determined the normal limits of fasting breath...

journal_title：Gastroenterology

authors： Perman JA,Modler S,Barr RG,Rosenthal P

更新日期：1984-12-01 00:00:00

abstract：:We studied the influence of morphine on intestinal secretion induced by three different secretogogues in an attempt to elucidate the mechanism for its antisecretory activity. In rabbit ileal mucosa in vitro morphine (10(-4) M) did not influence the electrical response to the subsequent administration of prostaglandin ...

journal_title：Gastroenterology

authors： McKay JS,Linaker BD,Higgs NB,Turnberg LA

更新日期：1982-02-01 00:00:00

abstract：:Serum gastrin and gastric endocrine cell numerical densities were examined in 22 patients with long-standing Zollinger-Ellison syndrome who were receiving either ranitidine, omeprazole, or other antisecretory drugs (SMS 201-995 or pirenzepine with or without ranitidine) for long periods of time. Fifteen patients had i...

journal_title：Gastroenterology

authors： Lehy T,Mignon M,Cadiot G,Elouaer-Blanc L,Ruszniewski P,Lewin MJ,Bonfils S

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND & AIMS:Estimates of complication rates following elective percutaneous liver biopsy vary and might not accurately reflect current practice. We studied mortality and complication rates, by indication, in patients after they underwent liver biopsies. METHODS:We performed a study using hospital episode statist...

journal_title：Gastroenterology

authors： West J,Card TR

更新日期：2010-10-01 00:00:00

abstract：:To look for possible HLA linkage in familial Crohn's disease, HLA haplotype segregation patterns were determined in 70 members of five kindreds, each having 2 or more patients with Crohn's disease (total number: 13 with Crohn's disease, 1 with ulcerative colitis). Concordant segregation of HLA haplotypes and disease w...

journal_title：Gastroenterology

authors： Eade OE,Moulton C,MacPherson BR,Andre-Ukena SS,Albertini RJ,Beeken WL

更新日期：1980-08-01 00:00:00

abstract：:Motor abnormalities of the small bowel that occur only during the waking state have been reported in the irritable bowel syndrome (IBS), suggesting that central nervous system arousal is a necessary condition for expression of the disorder and that it may reflect inappropriate brain-gut interaction. This possible rela...

journal_title：Gastroenterology

authors： Kumar D,Thompson PD,Wingate DL,Vesselinova-Jenkins CK,Libby G

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND & AIMS:Sjögren's syndrome and autoimmune pancreatitis are disorders with decreased function of salivary, lacrimal glands, and the exocrine pancreas. Nonobese diabetic/ShiLTJ mice and mice transduced with the cytokine BMP6 develop Sjögren's syndrome and chronic pancreatitis and MRL/Mp mice are models of autoi...

journal_title：Gastroenterology

authors： Zeng M,Szymczak M,Ahuja M,Zheng C,Yin H,Swaim W,Chiorini JA,Bridges RJ,Muallem S

更新日期：2017-10-01 00:00:00

abstract：:To determine if changes in intestinal motility occur during pregnancy, we studied small intestinal myoelectric activity, using monopolar electrodes, in fasted pregnant rats from day 12 to day 18 of the 22-day gestation period. We also studied fasting myoelectric activity in postpartum, nonpregnant, and castrate female...

journal_title：Gastroenterology

authors： Scott LD,Lester R,Van Thiel DH,Wald A

更新日期：1983-02-01 00:00:00

abstract：:Furosemide occasionally causes azotemia in patients with ascites, independently of induced volume depletion. To define this effect, we measured renal clearances in patients with chronic liver disease and ascites and in nonascitic controls. Furosemide (80 mg i.v.) transiently increased p-aminohippurate clearance in con...

journal_title：Gastroenterology

authors： Daskalopoulos G,Laffi G,Morgan T,Pinzani M,Harley H,Reynolds T,Zipser RD

更新日期：1987-06-01 00:00:00

abstract：:Twenty-one of 52 patients with regional enteritis had low serum zinc concentrations on initial testing. Fourteen of 31 patients followed longitudinally had low serum zinc concentrations. Two patients are presented as case reports who developed acrodermatitis skin lesions that responded to zinc therapy. Hypogonadism, g...

journal_title：Gastroenterology

authors： McClain C,Soutor C,Zieve L

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND & AIMS:Indomethacin impairs liver microsomal monooxygenase activities mediated by cytochrome P450 (CYP). We investigated the inhibition mechanism and the isoform selectivity in vitro and in vivo. METHODS:In an in vitro study, liver microsomes from male Wistar rats were preincubated with indomethacin and a r...

journal_title：Gastroenterology

authors： Masubuchi Y,Masuda E,Horie T

更新日期：2002-03-01 00:00:00

abstract：:To investigate the role of gastric inhibitory polypeptide (GIP), a potent inhibitor of gastric acid secretion, in the hypersecretion associated with duodenal ulcer, we compared the serum GIP concentrations in 11 healthy subjects and 16 duodenal ulcer patients after the stimulation of GIP release by a mixed meal. Fasti...

journal_title：Gastroenterology

authors： Cataland S,O'Dorisio TM,Brooks R,Mekhjian HS

更新日期：1977-07-01 00:00:00

abstract：:Confluent monolayers of epithelial cell lines of intestinal derivation may serve as useful models for studies of intestinal epithelial structure and function. Cells of the T84 line appear to be a useful model for studies of Cl- secretion. We now define the fine structure of this cell line, the structural events that o...

journal_title：Gastroenterology

authors： Madara JL,Stafford J,Dharmsathaphorn K,Carlson S

更新日期：1987-05-01 00:00:00

abstract：:An attempt was made to compare various morphometric parameters, including total hepatocyte number, with the in vivo clearances of aminopyrine and antipyrine in 26 cirrhotic and 14 noncirrhotic patients to evaluate the intact hepatocyte theory. Morphometric analysis was performed with a newly developed method using a c...

journal_title：Gastroenterology

authors： Kawasaki S,Imamura H,Bandai Y,Sanjo K,Idezuki Y

更新日期：1992-04-01 00:00:00

abstract：:We studied the procoagulant activity of peripheral blood monocytes in 41 patients with severe obstructive jaundice and in 27 nonjaundiced control patients using a one-stage clotting assay. Mononuclear cells from jaundiced patients, tested immediately after isolation, expressed low levels of procoagulant activity, whic...

journal_title：Gastroenterology

authors： Semeraro N,Montemurro P,Chetta G,Altomare DF,Giordano D,Colucci M

更新日期：1989-03-01 00:00:00

abstract：:Data collected by nine population-based tumor registries participating in the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute were analyzed to characterize the epidemiology of noncarcinoid adenocarcinomas of the colon and rectum in young adults. Tumors diagnosed in persons under 40...

journal_title：Gastroenterology

authors： Griffin PM,Liff JM,Greenberg RS,Clark WS

更新日期：1991-04-01 00:00:00

abstract：:It is possible to estimate hepatic triglyceride content by calculating the proton density fat fraction (PDFF), using proton magnetic resonance spectroscopy (1H-MRS), instead of collecting and analyzing liver biopsy specimens to detect steatosis. However, the current PDFF cut-off value (5%) used to define steatosis by ...

journal_title：Gastroenterology

authors： Nasr P,Forsgren MF,Ignatova S,Dahlström N,Cedersund G,Leinhard OD,Norén B,Ekstedt M,Lundberg P,Kechagias S

更新日期：2017-07-01 00:00:00

abstract：:Gastrointestinal symptoms occur in a large number of patients with food allergies. Immediate hypersensitivity mechanisms may give rise to the nausea, vomiting, abdominal pain, and diarrhea experienced by these patients. However, there are limited human data about the pathophysiological basis for these symptoms. Most o...

journal_title：Gastroenterology

authors： Crowe SE,Perdue MH

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with chronic hepatitis B virus (HBV) infection have a high risk for developing hepatocellular carcinoma (HCC). Patients with lower levels of hepatitis B surface antigen (HBsAg) have higher chances of losing HBsAg than those with high levels. However, little is known about whether higher level...

journal_title：Gastroenterology

authors： Tseng TC,Liu CJ,Yang HC,Su TH,Wang CC,Chen CL,Kuo SF,Liu CH,Chen PJ,Chen DS,Kao JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND & AIMS:Practice guidelines recommend that endoscopists spend at least 7 minutes examining the colonic mucosa during colonoscopy withdrawal to optimize polyp yield. The aim of this study was to determine if the implementation of an institution-wide policy of colonoscopy withdrawal time > or = 7 minutes was as...

journal_title：Gastroenterology

authors： Sawhney MS,Cury MS,Neeman N,Ngo LH,Lewis JM,Chuttani R,Pleskow DK,Aronson MD

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND & AIMS:Although different brands of fecal immunochemical tests (FITs) are used for colorectal cancer (CRC) screening, few studies have compared their accuracy in detecting advanced neoplasia. METHODS:We performed a large prospective cohort study within the Dutch national CRC screening program to evaluate 2 ...

journal_title：Gastroenterology

authors： Wieten E,de Klerk CM,van der Steen A,Ramakers CR,Kuipers EJ,Hansen BE,Lansdorp-Vogelaar I,Bossuyt PM,Dekker E,Spaander MCW

更新日期：2018-11-01 00:00:00