Abstract：
:We measured action potential duration (APD) from the endocardium (Endo) and epicardium (Epi) of the left ventricular free wall in Japanese monkey hearts and found that the APD of Endo is significantly longer than that of Epi at a stimulus cycle length of 1500 msec in normal Tyrode solution (control condition). We then hypothesized that shorter APD of Epi results from greater outward pump current and that the difference in the current may be due to a difference in membrane Na,K-ATPase activity between Endo and Epi. If this were the case, interventions which alter the Na,K-pump activity should alter electrophysiologic characteristics in the endocardium and the epicardium to different degrees. An application of ouabain (10(-6) M), an inhibitor of Na,K-ATPase, produced greater shortening of APD and greater depolarization of the resting potential in Endo as compared with Epi. Shortening of stimulus cycle length shortened the APD more markedly in Endo than Epi, resulting in a significantly longer APD in Epi than Endo at a stimulus cycle length of 200 msec. The hyperpolarization and the APD shortening produced when the tissues were returned to 5.4 mM K+ Tyrode solution from K+-free medium were also more marked in Endo than in Epi. Such findings suggest that endocardial cells are more liable to accumulate Na ions intracellularly and K ions extracellularly when the Na, K-pump is suppressed by ouabain or K+-free perfusion, presumably due to lower activity of Na, K-ATPase in Endo compared to Epi.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Imanishi S,Arita Mdoi
10.1016/s0022-0736(87)80015-8subject
Has Abstractpub_date
1987-07-01 00:00:00pages
185-92issue
3eissn
0022-0736issn
1532-8430journal_volume
20pub_type
杂志文章abstract：:Chemical necrosis was produced with the infiltration of 96 degrees alcohol on the middle anterosuperior segment 5 (nomenclature of the International Society for Computerized Electrocardiology) of the free left ventricular (LV) wall in 45 dogs and on the apical segment 10 and middle posterolateral segment 11 in 30 othe...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(94)80011-1
更新日期：1994-07-01 00:00:00
abstract：:An interpolated premature ventricular contraction (PVC) may produce either complete block of the next sinus impulse or depression of A-V nodal conduction with a prolonged A-H interval. When a PVC results in partial depression of a A-V nodal conduction, the effect on subsequent premature atrial stimuli is unknown. The ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(77)80025-3
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND:QT interval measured in the electrocardiogram (ECG) varies with RR interval challenging the calculation of corrected QT (QTc) in Atrial fibrillation (AF). OBJECTIVES:To identify the ideal Lead, number of complexes and the formula to measure QTc that correlates best between AF and sinus rhythm (SR). PROCEDU...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.06.009
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:It is not always feasible to use standard electrode placement for limb leads when recording the 12-lead electrocardiogram (ECG). Other electrode placements have been accepted during monitoring. Nonstandard electrode positions, however, fail to produce waveforms identical to those recorded from the distal lim...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2010.11.012
更新日期：2011-03-01 00:00:00
abstract：:A 58-year-old woman with a history of multi-origin atrial tachycardia and limb-girdle muscular dystrophy was treated for presyncope caused by pauses in atrial rhythm. A dual-chamber pacemaker was implanted. The low-voltage area extended broadly, but 10-V pacing could not capture the large right atrium, including the r...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2020.05.003
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Reducing time to reperfusion treatment for patients with ST-segment elevation myocardial infarction (STEMI) improves patient outcomes. Few medical systems consistently meet current benchmarks regarding timely access to treatment. Studies have widely demonstrated that prehospital 12-lead electrocardiography c...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2009.03.011
更新日期：2009-09-01 00:00:00
abstract：:We describe a 75-year-old male patient with two-vessel coronary artery disease, who developed transient left posterior hemiblock (LPH) while undergoing an exercise treadmill test (ETT). The intraventricular conduction abnormality initially had the features of alternating LPH, which evolved to stable LPH prior to dissi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/s0022-0736(99)90022-5
更新日期：1999-01-01 00:00:00
abstract：:His bundle electrograms of 40 patients developing Wenckebach block during atrial pacing and four with spontaneous Wenckebach block above the His were reviewed to determine the frequency of classical Wenckebach periodicity. Thirty patients had 143 Wenckebach cycles that were suitable for analysis. Cycles were evaluated...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(75)80003-3
更新日期：1975-01-01 00:00:00
abstract：:Repetitive nonreentrant ventriculoatrial synchrony during dual-chamber pacing is characterized by long intervals alternating with short intervals. This arrangement activated automatic mode switching in a St Jude dual-chamber pacemaker in which the algorithm requires an atrial sensed event for automatic mode switching ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2012.04.003
更新日期：2012-07-01 00:00:00
abstract：:Body surface potential mapping was performed in 60 clinical cases and an ideal 0 potential was calculated in each case at 2msec intervals, which corresponds to the potential at infinity. Maximal deviation of the Wilson terminal voltage the ideal potential was 0.14mv on the average. Time course of potential variations ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(05)80054-8
更新日期：1995-10-01 00:00:00
abstract：:This report presents an unusual type of conduction disturbance of the left bundle branch which appeared in a patient with acute bacterial endocarditis of the aortic valve in which the septum was also invaded. This is the first case found in which the partial left bundle branch block (LBBB) was of acute inflammatory or...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(77)80073-3
更新日期：1977-07-01 00:00:00
abstract：:Reliable cardiovascular (CV) risk assessment by a noninvasive tool would be of great value for CV event prevention. The present study consists of 187 coronary artery disease patients with 8 years of follow-up. Eight vectorcardiographic parameters characterizing different aspects of ventricular repolarization were anal...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2010.05.004
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Our aim was to evaluate the intermittent use of a handheld ECG system for detecting silent arrhythmias and cardiac autonomic dysfunction in children with univentricular hearts. METHODS:Twenty-seven patients performed intermittent ECG recordings with handheld devices during a 14-day period. A manual arrhythm...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2014.02.006
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Sudden arousal has been associated with sudden cardiac death in individuals with ischemic heart disease, cardiac arrhythmias, and the congenital long QT syndrome. This study aimed to determine the effects of arousal on ventricular repolarization in normal individuals by examining the dynamic QT interval-hear...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/j.jelectrocard.2005.10.006
更新日期：2006-07-01 00:00:00
abstract：:This study describes a method for improving the day-to-day and minute-to-minute repeatability of the deterministic computer-assisted diagnosis of left ventricular hypertrophy. Conventional upper limits of normal for many age-dependent electrocardiographic parameters have been replaced by continuous equations, thereby,...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：AIMS:This investigation addresses procedural characteristics of catheter ablation in patients with atrial fibrillation (AF) and sinus bradycardia. METHODS:From the prospective, multi-center German Ablation Registry 1073 patients with sinus rhythm at the time of AF ablation were divided into two groups according to hea...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jelectrocard.2015.12.007
更新日期：2016-03-01 00:00:00
abstract：:A method has been developed for establishing a "University Without Walls" for the purpose of studying the relationship between electrocardiographic estimation and magnetic resonance imaging measurements of myocardial infarct size. The research team includes faculty and students from 4 medical centers, with expertise e...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.2001.28810
更新日期：2001-01-01 00:00:00
abstract：:A graph consisting of small squares of equal size preprinted on a transparent plastic chart can be used for a quick and accurate calculation of the VCG loop area in each quadrant of the three conventional planes. ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(79)80013-8
更新日期：1979-10-01 00:00:00
abstract：BACKGROUND:Electrocution injury (EI) is a major problem in developing countries. The aim of this study is to investigate the effect of EI on electrocardiographic (ECG) parameters. METHODS:A total of 43 patients hospitalized with diagnosis of EI were prospectively enrolled. Admission ECGs were compared with follow-up E...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.06.009
更新日期：2015-09-01 00:00:00
abstract：:An extremely rare case of intermittent ventricular parasystolic bigeminy is presented, in which coexisting reentrant ventricular extrasystoles of sinus origin, showing mainly trigeminy, and those of ventricular parasystolic origin, showing a close coupling to the ventricular parasystolic beat, are demonstrated. Such a...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(90)90139-s
更新日期：1990-04-01 00:00:00
abstract：INTRODUCTION:"Cardiac memory" (CM) refers to a change in repolarization induced by an altered pathway of activation, manifested after resumption of spontaneous ventricular activation (SVA). AIMS:To investigate for the first time in humans the effects of left ventricular (LV) pacing on CM development through vectorcard...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.05.007
更新日期：2015-07-01 00:00:00
abstract：:Five male patients with chronic stable ventricular arrhythmias underwent a placebo controlled ascending dose study with oral cibenzoline, a new type 1 antiarrhythmic drug. Ambulatory ECG (Holter) recordings and electrophysiologic studies were done while on placebo and on the maximum dose of cibenzoline. Drug toxicity,...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0022-0736(84)80020-5
更新日期：1984-01-01 00:00:00
abstract：:Although solid angle analysis has been considered to be reasonable for explaining the distribution of ST segment deviation following ischemia, it has not been tested fully, especially for ST segment changes in various sites at different lead surfaces. Thus, we investigated the applicability of solid angle theory to th...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(86)80033-4
更新日期：1986-07-01 00:00:00
abstract：:To investigate the effects of electrolytes on anterograde conduction via accessory pathways, 12 patients with Wolff-Parkinson-White syndrome received, while in sinus rhythm, intravenous KCl (7 mEq in 200 mL of 0.9% NaCl), MgSO4 (10 mL 20% in 200 mL of 0.9% NaCl), NaCl (0.9%, 200 mL), and procainamide (maximal dose, 10...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0022-0736(96)80106-3
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:ECG screening of young athletes for risk of sudden cardiac death has grown in popularity throughout the world. The purpose of this study is to assess the technical error rate of ECGs acquired by appropriately trained community volunteers compared to that reported in the literature utilizing train...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2015.02.007
更新日期：2015-05-01 00:00:00
abstract：:An image torso may be viewed as a one-to-one transform of a physical volume conductor to a geometric form which defines both the axis and sensitivity of any electrocardiographic connection. In this report, the image surfaces of laminar, spherical, rectangular and humanoid physical torsos are explored theoretically and...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(77)80037-x
更新日期：1977-01-01 00:00:00
abstract：:Intracellular and extracellular recording techniques were used to study triggered activity in tissues isolated from the inferior right atrium of the dog. In the presence of norepinephrine (greater than 10(-7) M) single stimuli or short rapid pacing elicited action potentials with delayed after-depolarizations, leading...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(87)90005-7
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:In STEMI, grade-3 ischemia (G3) on admission ECG predicts larger infarct size (IS) than grade-2 (G2). We evaluated whether pre-hospital G3 and its temporal behavior are associated with IS and salvage after pPCI. METHODS:In 401 STEMI patients, pre-hospital and pre-PCI ECGs were classified as G3 or G2. IS was...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jelectrocard.2014.04.012
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVES:To define clinical correlates of low voltage isolated to precordial leads on the surface electrocardiogram (ECG). INTRODUCTION:Low voltage (V) on the ECG is defined as QRS V<5mm in all limb leads and <10mm in all precordial leads. The diagnostic use of ECGs with low voltage isolated to the precordial leads ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.04.016
更新日期：2017-01-01 00:00:00
abstract：:Atrioventricular node reentry tachycardia is an incompletely understood substrate for supraventricular tachycardia. Although there is agreement that the mechanism involves functionally separate fast and slow AV node pathways, which are somewhat anatomically discrete, the anatomical basis for the reentrant circuit is n...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2008.06.016
更新日期：2008-11-01 00:00:00
