当前位置： SCI文献检索 > EUROPEAN JOURNAL OF PEDIATRICS期刊下所有文献 > Nicotine and cotinine concentrations in the milk of smoking mothers: influence of cigarette consumption and diurnal variation.

Nicotine and cotinine concentrations in the milk of smoking mothers: influence of cigarette consumption and diurnal variation.

Abstract：

:The relationship between nicotine and cotinine concentrations in mother's milk (including 24 h profiles) and the number of cigarettes consumed was studied. A total of 206 milk samples were collected from 34 nursing, smoking mothers. The mothers were distributed into three groups: Group I (1-10 cigarettes/day), group II (11-20 cigarettes/day) and group III (21-40 cigarettes/day). Milk samples from all nursing periods of a 24 h interval were collected. Nicotine and cotinine concentrations were measured by specific gas chromatographic techniques. The average milk nicotine and cotinine concentrations over a 24 h interval in the three groups were as follows: group I, 18 +/- 16 and 76 +/- 33 ng/ml; group II, 28 +/- 21 and 125 +/- 60 ng/ml; group III, 48 +/- 25 and 230 +/- 62 ng/ml (means +/- SD). Over a time interval of 24 h the nicotine concentrations varied greatly in the milk of smoking mothers, while the cotinine concentrations remained relatively constant. Because of the great intra- and inter-individual variations in the nicotine concentrations, the influence of the number of cigarettes smoked on the nicotine concentration in milk was most apparent if nicotine concentrations were measured repeatedly over a prolonged time interval. Our results indicate that the exposure of the nursed infant to nicotine and cotinine via milk depends on the daily cigarette consumption but also on individual smoking habits; the time of smoking, smoking frequency prior to nursing, and the time interval between nursing and the last cigarette.

journal_name

Eur J Pediatr

journal_title

European journal of pediatrics

authors

Luck W,Nau H

doi

10.1007/BF00647276

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

21-6

issue

1

eissn

0340-6199

issn

1432-1076

journal_volume

146

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF PEDIATRICS文献大全
  • From adolescents to adults with congenital heart disease: the role of transition.

    abstract：UNLABELLED:Improved surgical care during the last decades, together with advances in medical management, led to a remarkable increase in survival of patients with congenital heart disease (CHD). However, aging of the CHD population brings new challenges, and loss of follow-up of adolescents and adults with CHD is a maj...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-015-2557-x

    authors： Moceri P,Goossens E,Hascoet S,Checler C,Bonello B,Ferrari E,Acar P,Fraisse A

    更新日期：2015-07-01 00:00:00

  • Quality control for selective screening of inborn errors of metabolism.

    abstract：:A comprehensive program for proficiency testing of biochemical genetics laboratories is described. Inborn errors of metabolism of amino acids, organic acids, glycosaminoglycans and oligosaccharides are covered, as well as the assay of galactose-1-phosphate. Participants are not only required to report the analytical r...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02138772

    authors： Hommes FA

    更新日期：1994-01-01 00:00:00

  • Evolution of the proportion of patients with Down's syndrome karyotyped in Belgium since 1960.

    abstract：:Estimation of the total number of infants with DS born each year in Belgium allows evaluation of changes in the proportion of children with DS in whom a karyotype has been established. This proportion steadily increased to 95% of the children with DS born in 1978. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00442300

    authors： Evers-Kiebooms G,Vlietinck R,van den Berghe H

    更新日期：1985-03-01 00:00:00

  • Severe X-linked chronic granulomatous disease in two unrelated females.

    abstract：:Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by mutations of one of the subunits of phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase leading to decreased or complete absence of neutrophil oxidative burst. We report the clinical and laboratory findings in tw...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-006-0211-3

    authors： Chollet-Martin S,Lopez A,Gaud C,Henry D,Stos B,El Benna J,Chedevile G,Gendrel D,Gougerot-Pocidalo MA,Grandchamp B,Gérard B

    更新日期：2007-02-01 00:00:00

  • Effects of continuing paediatric education in interpersonal communication skills.

    abstract：UNLABELLED:Paediatric care places great demands on interpersonal communication skills, especially as regards the handling of psychosocial issues. Recent shifts in paediatric morbidity and increases in patient empowerment furthermore emphasize the need for continuing paediatric education in communication skills. It is, ...

    journal_title：European journal of pediatrics

    pub_type： 临床试验,杂志文章

    doi：10.1007/s004310051316

    authors： van Dulmen AM,Holl RA

    更新日期：2000-07-01 00:00:00

  • Influence of blood pressure level and age on within-visit blood pressure variability in children and adolescents.

    abstract：:Blood pressure (BP) is variable in children and this could affect BP assessment, but the magnitude of within-visit BP variability (BPV) over consecutive measurements has never been investigated. This study aimed to determine the direction and magnitude of, and factors affecting, within-visit BPV in children and adoles...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-017-3049-y

    authors： Veloudi P,Blizzard CL,Srikanth VK,Schultz MG,Sharman JE

    更新日期：2018-02-01 00:00:00

  • Stepwise interventional approach in a neonate with pulmonary valve atresia and intact ventricular septum.

    abstract：UNLABELLED:In neonates with pulmonary atresia and intact ventricular septum the aims of therapy are maintenance of pulmonary blood flow and right ventricular decompression in order to achieve right ventricular support of the pulmonary circulation. Recent developments in interventional heart catheterization with pulmona...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s004310050960

    authors： Bökenkamp R,Kaulitz R,Paul T,Hausdorf G

    更新日期：1998-11-01 00:00:00

  • Neurophysiological findings in long-term survivors of acute lymphoblastic leukaemia in childhood treated with the BFM protocol 81 SR-A/B.

    abstract：UNLABELLED:Monitoring of therapy-related late effects after acute lymphoblastic leukaemia (ALL) therapy in childhood has become an increasingly important field in posttherapeutic patient surveillance. The usefulness of neurophysiological investigations (e.g. EEG, evoked potentials (EP)) as part of these attempts is con...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s004310050700

    authors： Ueberall MA,Skirl G,Strassburg HM,Wenzel D,Hertzberg H,Langer T,Meier W,Berger-Jones K,Huk WJ,Korinthenberg R,Beck JD

    更新日期：1997-09-01 00:00:00

  • Acute idiopathic scrotal oedema: four cases and a short review.

    abstract：:We report four cases of acute idiopathic scrotal oedema, an underreported cause of acute painless or moderately painfull swelling and erythema of the scrotum in young boys. It is a self-limiting disease and to prevent unnecessary surgical exploration or antibiotic therapy, it is very important to distinguish acute idi...

    journal_title：European journal of pediatrics

    pub_type： 信件

    doi：10.1007/s004310100771

    authors： van Langen AM,Gal S,Hulsmann AR,De Nef JJ

    更新日期：2001-07-01 00:00:00

  • Clinical practice. NTBC therapy for tyrosinemia type 1: how much is enough?

    abstract：UNLABELLED:Four patients with tyrosinemia type 1 (ages 6-32 months) were treated with 2-(2-nitro-4-trifluoro-methylbenzoyl)-1,3-cyclohexandion (NTBC) at Cairo University Children's Hospital, Egypt and followed up for 12-27 months. The recommended average dose of NTBC is 1 mg/kg/day. They were started on the following d...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-009-1090-1

    authors： El-Karaksy H,Rashed M,El-Sayed R,El-Raziky M,El-Koofy N,El-Hawary M,Al-Dirbashi O

    更新日期：2010-06-01 00:00:00

  • A national educational campaign to raise awareness of child physical abuse among health care professionals.

    abstract：:Education is necessary to improve child physical abuse detection and management. A few studies have described national child abuse training programs, but none has measured changes in knowledge among participants. A collaboration of child abuse experts from the USA, an academic pediatric department, and a non-governmen...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-020-03625-4

    authors： Soldatou A,Stathi A,Panos A,Paouri B,Koutsoukou E,Krepis P,Tsolia M,Oral R,Leventhal JM

    更新日期：2020-09-01 00:00:00

  • From hyperinsulinaemic hypoglycaemia to ketotic hypoglycaemia: the range of glucose abnormalities in patients born with intrauterine growth retardation.

    abstract：INTRODUCTION:Newborns with intrauterine growth retardation (IUGR) have multiple risk factors for developing hypoglycaemia. Hyperinsulinism, both transient and prolonged, is one of the major risk factors responsible for the hypoglycaemia observed in some newborns with IUGR. Once the child has progressed beyond the infan...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-006-0371-1

    authors： Kochar IS,Hussain K

    更新日期：2007-10-01 00:00:00

  • IgG subclass deficiency in children with recurrent bronchitis.

    abstract：:We studied the incidence of IgG subclass deficiency in children with recurrent bronchitis. Recurrent bronchitis was defined as three or more episodes a year during at least 2 consecutive years, of bronchopulmonary infection, productive cough with or without fever and/or diffuse râles by physical examination in the abs...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02072228

    authors： DeBaets F,Kint J,Pauwels R,Leroy J

    更新日期：1992-04-01 00:00:00

  • Clinical characteristics and outcome of children stung by scorpion.

    abstract：UNLABELLED:Scorpion envenomation is a health problem in children in tropical and subtropical regions. The aim of this study was to evaluate demographic and clinical characteristics as well as outcomes in referred children to Assiut University Children Hospital during the year 2012 with a history of scorpion sting. The ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-013-2244-8

    authors： Mohamad IL,Elsayh KI,Mohammad HA,Saad K,Zahran AM,Abdallah AM,Tawfeek MS,Monazea EM

    更新日期：2014-06-01 00:00:00

  • Anti-glomerular basement membrane antibody-mediated glomerulonephritis due to glue sniffing.

    abstract：:A 16-year-old girl developed rapidly progressive glomerulonephritis and renal failure. The disease was associated with high titres of antiglomerular basement membrane antibodies in serum, linear deposits of immunoglobulin G and diffuse epithelial crescents on renal biopsy. Past history revealed heavy smoking and delib...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00716479

    authors： Bonzel KE,Müller-Wiefel DE,Ruder H,Wingen AM,Waldherr R,Weber M

    更新日期：1987-05-01 00:00:00

  • Predictive factors for the effect of gonadotrophin releasing hormone analogue therapy on the height of girls with idiopathic central precocious puberty.

    abstract：:The factors influencing the final height of central precocious puberty patients treated with gonadotrophin releasing hormone (GnRH) analogues remain a critical issue. This study compares the predicted final height before and after GnRH analogue therapy to identify predictive factors for final height. Fourteen girls wi...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01959077

    authors： Brauner R,Malandry F,Rappaport R

    更新日期：1992-10-01 00:00:00

  • Severe respiratory syncytial virus bronchiolitis in children: from short mechanical ventilation to extracorporeal membrane oxygenation.

    abstract：UNLABELLED:The objective of this study was to describe the characteristics of children who required mechanical ventilation (MV) or extracorporeal membrane oxygenation (ECMO) support for respiratory syncytial virus (RSV) bronchiolitis, and to identify risk factors associated with disease severity assessed by duration of...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-004-1580-0

    authors： Flamant C,Hallalel F,Nolent P,Chevalier JY,Renolleau S

    更新日期：2005-02-01 00:00:00

  • COVID-19 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review of critically unwell children and the association with underlying comorbidities.

    abstract：:Data show that children are less severely affected with SARS-Covid-19 than adults; however, there have been a small proportion of children who have been critically unwell. In this systematic review, we aimed to identify and describe which underlying comorbidities may be associated with severe SARS-CoV-2 disease and de...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-020-03801-6

    authors： Williams N,Radia T,Harman K,Agrawal P,Cook J,Gupta A

    更新日期：2020-09-10 00:00:00

  • From sleep duration to childhood obesity--what are the pathways?

    abstract：UNLABELLED:Sleep duration has been identified as risk factor for obesity already in children. Besides investigating the role of fat mass (FM), this study addressed the question whether endocrine mechanisms act as intermediates in the association between sleep duration and overweight/obesity. Within the framework of the...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00431-011-1670-8

    authors： Börnhorst C,Hense S,Ahrens W,Hebestreit A,Reisch L,Barba G,von Kries R,Bayer O,IDEFICS Consortium.

    更新日期：2012-07-01 00:00:00

  • Prediction of outcome from the chest radiograph appearance on day 7 of very prematurely born infants.

    abstract：UNLABELLED:Our aim was to determine whether the chest radiograph appearance at 7 days predicted chronic lung disease development (oxygen dependency at 36 weeks post-menstrual age) or death before discharge and if it was a better predictor than readily available clinical data. Two consecutive studies were performed. In ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-003-1332-6

    authors： Greenough A,Thomas M,Dimitriou G,Williams O,Johnson A,Limb E,Peacock J,Marlow N,Calvert S

    更新日期：2004-01-01 00:00:00

  • Haemorrhagic diathesis as a possible early sign of hereditary fructose intolerance.

    abstract：:An infant girl three weeks of age with the leading symptom of skin haemorrhages is presented. On further investigation, the signs of severe hepatic damage with hypofibrinogenaemia and prothrombin complex impairment, and renal tubular dysfunction were disclosed. All these pathological symptoms, which were reversed on f...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00465567

    authors： Hosková A,Mrskos A

    更新日期：1977-12-30 00:00:00

  • Osteoporosis-pseudoglioma syndrome: clinical, genetic, and treatment-response study of 10 new cases in Greece.

    abstract：:Osteoporosis-pseudoglioma syndrome (OPPG) is a rare autosomal-recessive disorder, characterized by severe osteoporosis and early-onset blindness. Loss of function mutations in the gene encoding low-density lipoprotein receptor-related protein 5 (LRP5) have been established as the genetic defect of the disease. We repo...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-018-3299-3

    authors： Papadopoulos I,Bountouvi E,Attilakos A,Gole E,Dinopoulos A,Peppa M,Nikolaidou P,Papadopoulou A

    更新日期：2019-03-01 00:00:00

  • Desquamative interstitial pneumonitis and alveolar lipoproteinosis: diagnostic difficulties and therapy problems with an infant.

    abstract：:A desquamative, interstitial pneumonitis was diagnosed histologically in a 9-month-old boy who first became ill at the age of 5 weeks. The desquamative interstitial pneumonitis was associated with an acquired cytomegalovirus (CMV) infection. Despite treatment with corticoids, acyclovir and artificial ventilation, the ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02429072

    authors： Schneider K,Brünstler I,Vogel H,Fendel H,Remberger K

    更新日期：1986-12-01 00:00:00

  • Frequency of coeliac disease in Hungarian children with type 1 diabetes mellitus.

    abstract：:Coeliac disease and type 1 diabetes mellitus can frequently coexist, presumably due to a common genetic predisposition. The present study was designed to evaluate the frequency of coeliac disease among Hungarian diabetic children and to study the effect of gluten-free diet on glycaemic control. A total of 205 diabetic...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-002-1103-9

    authors： Arató A,Körner A,Veres G,Dezsöfi A,Ujpál I,Madácsy L

    更新日期：2003-01-01 00:00:00

  • Crohn disease with sclerosing cholangitis and liver cirrhosis in adolescence.

    abstract：:A 17-year-old patient suffering from Crohn disease (CD) and liver cirrhosis is presented. At an advanced stage of the disease, he died of a concomitant urosepsis. Autopsy showed that the liver cirrhosis was caused by sclerosing cholangitis. This very rare complication of CD in adolescence is discussed. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02072206

    authors： Ramelli GP,Tönz O,Zimmermann A,Lentze MJ

    更新日期：1991-06-01 00:00:00

  • Ring chromosome 7: report of the fifth case.

    abstract：:A 13-year-old boy with a 46,XY,r(7) karyotype presented with growth failure, microcephaly, achromic spots and multiple pigmented naevi. Psychomotor development was normal and no major malformations were present. Comparison with four previously reported patients with ring chromosome 7 shows that the most frequent findi...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/BF01959398

    authors： Caramia GM,Baroncini A,Osimani P,Forabosco A

    更新日期：1990-04-01 00:00:00

  • Variable outcome of experimental interferon-gamma therapy of disseminated Bacillus Calmette-Guerin infection in two unrelated interleukin-12Rbeta1-deficient Slovakian children.

    abstract：UNLABELLED:Mycobacterium bovis Bacillus Calmette-Guerin (BCG) is an attenuated live vaccine that may cause life-threatening clinical disease in children with impaired immunity. In particular, patients with any of the nine known inherited disorders of the interleukin-12/23 interferon-gamma (IL-12/23-IFNgamma) axis are h...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-004-1599-2

    authors： Ulrichs T,Fieschi C,Nevicka E,Hahn H,Brezina M,Kaufmann SH,Casanova JL,Frecerova K

    更新日期：2005-03-01 00:00:00

  • Unilateral decompressive craniectomy for children with severe brain injury. Report of seven cases and review of the relevant literature.

    abstract：UNLABELLED:Severe head injuries in children (under 15 years of age) have many features that differentiate them from head injuries in adults. In such cases, non-surgical treatment cannot always prevent fatal herniation. We report on seven cases of children with severe head injury, presenting with decorticate posturing a...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-001-0864-x

    authors： Hejazi N,Witzmann A,Fae P

    更新日期：2002-02-01 00:00:00

  • New insights into lipid and fatty acid metabolism via stable isotopes.

    abstract：UNLABELLED:Dynamic processes are of great interest in the study of lipid and fatty acid metabolism. Their in vivo investigation is now possible with the use of stable isotope tracers and the available sensitive analytical technology. We present some examples demonstrating the assessment of lipid oxidation as well as mo...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/pl00014276

    authors： Demmelmair H,Sauerwald T,Koletzko B,Richter T

    更新日期：1997-08-01 00:00:00

  • Insulin-sensitive obese children display a favorable metabolic profile.

    abstract：UNLABELLED:Most of what is known about the metabolically healthy obese phenomenon is derived from studies in the adult population and no standardized criteria to identify these individuals exist to date. The aim of this study was to determine if the preserved insulin sensitivity evaluated by homeostatic model assessmen...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-012-1867-5

    authors： Vukovic R,Mitrovic K,Milenkovic T,Todorovic S,Soldatovic I,Sipetic-Grujicic S,Zdravkovic D

    更新日期：2013-02-01 00:00:00