Anti-glomerular basement membrane antibody-mediated glomerulonephritis due to glue sniffing.

Abstract:

:A 16-year-old girl developed rapidly progressive glomerulonephritis and renal failure. The disease was associated with high titres of antiglomerular basement membrane antibodies in serum, linear deposits of immunoglobulin G and diffuse epithelial crescents on renal biopsy. Past history revealed heavy smoking and deliberate sniffing of Pattex glue, a mixture of hydrocarbons which possibly may affect the structure of glomerular basement membrane. After treatment by repeated plasmapheresis and drug immunosuppression autoantibodies disappeared from serum but renal function was not influenced. Renal damage is a potential hazard for glue sniffing adolescents.

journal_name

Eur J Pediatr

authors

Bonzel KE,Müller-Wiefel DE,Ruder H,Wingen AM,Waldherr R,Weber M

doi

10.1007/BF00716479

subject

Has Abstract

pub_date

1987-05-01 00:00:00

pages

296-300

issue

3

eissn

0340-6199

issn

1432-1076

journal_volume

146

pub_type

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