当前位置： SCI文献检索 > Brachytherapy期刊下所有文献 > First clinical implementation of GammaTile permanent brain implants after FDA clearance.

First clinical implementation of GammaTile permanent brain implants after FDA clearance.

Abstract：

PURPOSE:GammaTile cesium-131 (131Cs) permanent brain implant has received Food and Drug Administration (FDA) clearance as a promising treatment for certain brain tumors. Our center was the first institution in the United States after FDA clearance to offer the clinical use of GammaTile brachytherapy outside of a clinical trial. The purpose of this work is to aid the medical physicist and radiation oncologist in implementing this collagen carrier tile brachytherapy (CTBT) program in their practice. METHODS:A total of 23 patients have been treated with GammaTile to date at our center. Treatment planning system (TPS) commissioning was performed by configuring the parameters for the 131Cs (IsoRay Model CS-1, Rev2) source, and doses were validated with the consensus data from the American Association of Physicists in Medicine TG-43U1S2. Implant procedures, dosimetry, postimplant planning, and target delineations were established based on our clinical experience. Radiation safety aspects were evaluated based on exposure rate measurements of implanted patients, as well as body and ring badge measurements. RESULTS:An estimated timeframe of the GammaTile clinical responsibilities for the medical physicist, radiation oncologist, and neurosurgeon is presented. TPS doses were validated with published dose to water for 131Cs. Clinical aspects, including estimation of the number of tiles, treatment planning, dosimetry, and radiation safety considerations, are presented. CONCLUSION:The implementation of the GammaTile program requires collaboration from multiple specialties, including medical physics, radiation oncology, and neurosurgery. This manuscript provides a roadmap for the implementation of this therapy.

journal_name

Brachytherapy

journal_title

Brachytherapy

authors

Ferreira C,Sterling D,Reynolds M,Dusenbery K,Chen C,Alaei P

doi

10.1016/j.brachy.2020.12.005

subject

Has Abstract

pub_date

2021-01-21 00:00:00

eissn

1538-4721

issn

1873-1449

pii

S1538-4721(20)30295-6

pub_type

杂志文章

相关文献

Brachytherapy文献大全
  • Reirradiation of paraaortic lymph node metastasis by brachytherapy with hyaluronate injection via paravertebral approach: With DVH comparison to IMRT.

    abstract：UNLABELLED:PURPOSE/INTRODUCTION: To safely irradiate retroperitoneal targets as paraaortic lymph node by separating abdominal at-risk organs from the target during irradiation, we created a percutaneous paravertebral approach of high-dose-rate brachytherapy with hyaluronate gel injection (HGI). We report a case treated...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2011.12.004

    authors： Kishi K,Sonomura T,Shirai S,Noda Y,Sato M,Ikushima H,Oh RJ

    更新日期：2013-01-01 00:00:00

  • GERICO-03 phase II trial of accelerated and partial breast irradiation in elderly women: feasibility, reproducibility, and impact on functional status.

    abstract：PURPOSE:To analyze the feasibility, reproducibility, and impact on functional status of postoperative accelerated and partial breast irradiation (APBI) using interstitial high-dose rate-brachytherapy in women older than 70 years. METHODS AND MATERIALS:From July 2004 to April 2008, 46 patients were screened for enrollm...

    journal_title：Brachytherapy

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.brachy.2012.06.004

    authors： Hannoun-Levi JM,Gourgou-Bourgade S,Belkacemi Y,Chara-Bruneau C,Hennequin C,Quetin P,Orsini C,Brain E,Marsiglia H

    更新日期：2013-07-01 00:00:00

  • Long-term outcomes analysis of low-dose-rate brachytherapy in clinically T3 high-risk prostate cancer.

    abstract：PURPOSE:The available data demonstrating that superiority of LDR brachytherapy (LDR-BT) boost in high-risk prostate cancer patients under represents patients with extracapsular extension (T3a) and/or seminal vesicle invasion (T3b) have been limited. We report long-term clinical outcomes data for patients with cT3a/b di...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2018.07.001

    authors： Agarwal M,Chhabra AM,Amin N,Braccioforte MH,Molitoris JK,Moran BJ

    更新日期：2018-01-01 00:00:00

  • Intraoperative adaptive brachytherapy of iodine-125 prostate implants guided by C-arm cone-beam computed tomography-based dosimetry.

    abstract：PURPOSE:(1) To demonstrate the feasibility of C-arm cone-beam computed tomography (CBCT)-based postplanning and subsequent adaptation of underdosed critical areas by adding remedial seeds during the transrectal ultrasound (TRUS)-guided implantation of (125)I seeds and (2) to assess the duration of this procedure. METH...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2007.08.005

    authors： Westendorp H,Hoekstra CJ,van't Riet A,Minken AW,Immerzeel JJ

    更新日期：2007-10-01 00:00:00

  • Is prostate-specific antigen percentage decrease predictive of clinical outcome after permanent iodine-125 interstitial brachytherapy for prostate cancer?

    abstract：OBJECTIVE:To determine the usefulness of prostate-specific antigen (PSA) percentage (vs. pretreatment value assumed as 100%) in prediction of biochemical relapse, after iodine-125 ((125)I) permanent brachytherapy for prostate cancer, to employ a parameter independent by the initial PSA amount and by the individual pros...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2011.08.008

    authors： Paoluzzi M,Mignogna M,Lorenzini E,Valent F,Fontana N,Pinzi N,Repetti F,Ponchietti R

    更新日期：2012-07-01 00:00:00

  • Minimal channel GreenLight photovaporization before permanent implant prostate brachytherapy for patients with obstructive symptoms: Technically feasible and safe.

    abstract：PURPOSE:Brachytherapy (BrT) is a standard treatment for low-risk to favorable-intermediate-risk prostate cancer but is a relative contraindication for patients with obstructive symptoms. We aimed to assess the feasibility and urinary toxicity of a minimal photovaporization (mPVP) before implantation. MATERIALS AND MET...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2020.08.003

    authors： Peigne C,Fournier G,Dissaux G,Delage F,Coquet JB,Boussion N,Goasduff G,Malhaire JP,Pradier O,Schick U,Valeri A

    更新日期：2021-01-01 00:00:00

  • Breast conservation surgery and interstitial brachytherapy in the management of locally recurrent carcinoma of the breast: the Allegheny General Hospital experience.

    abstract：PURPOSE:To evaluate lumpectomy followed by interstitial brachytherapy as an acceptable salvage therapy for women who have developed localized recurrence of breast cancer after conservation surgery and postoperative external radiotherapy. METHODS AND MATERIALS:Between 1/1998 and 10/2006, 21 patients with T0 or T1 in-br...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2007.12.001

    authors： Trombetta M,Julian T,Bhandari T,Werts ED,Miften M,Parda D

    更新日期：2008-01-01 00:00:00

  • Optimization of prostate brachytherapy techniques with polyethylene glycol-based hydrogel spacers: A systematic review.

    abstract：PURPOSE:The objective of this overview was to critically evaluate the effect of polyethylene glycol (PEG)-based hydrogel spacers during prostate brachytherapy with regard to dosimetric and clinical benefits, as well as procedure-related toxicity. METHODS AND MATERIALS:A systematic search in the PubMed database was per...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2019.08.009

    authors： Afkhami Ardekani M,Ghaffari H

    更新日期：2020-01-01 00:00:00

  • Five fraction accelerated partial breast irradiation using noninvasive image-guided breast brachytherapy: Feasibility and acute toxicity.

    abstract：PURPOSE:To improve efficiency, convenience, and cost, a prospective phase II trial was initiated to evaluate accelerated partial breast irradiation delivered with noninvasive image-guided breast brachytherapy (NIBB) via five once-daily fractions. METHODS AND MATERIALS:Women ≥50 years old with early-stage breast cancer...

    journal_title：Brachytherapy

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.brachy.2018.05.006

    authors： Hepel JT,Yashar C,Leonard KL,Einck JP,Sha S,DiPetrillo T,Wiggins D,Graves TA,Edmonson D,Brown University Oncology Research Group.,Wazer DE

    更新日期：2018-01-01 00:00:00

  • Needle migration and dosimetric impact in high-dose-rate brachytherapy for prostate cancer evaluated by repeated MRI.

    abstract：PURPOSE:To quantify needle migration and dosimetric impact in high-dose-rate brachytherapy for prostate cancer and propose a threshold for needle migration. METHODS AND MATERIALS:Twenty-four high-risk prostate cancer patients treated with an HDR boost of 2 × 8.5 Gy were included. Patients received an MRI for planning ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2017.08.005

    authors： Buus S,Lizondo M,Hokland S,Rylander S,Pedersen EM,Tanderup K,Bentzen L

    更新日期：2018-01-01 00:00:00

  • Locally advanced cervical cancer in renal transplant patients: a dilemma between control and toxicity.

    abstract：PURPOSE:Treatment of locally advanced cervical cancer in patients with a renal graft requires precautions. The graft is usually in a pelvic position, close to the clinical target volume (CTV). Preserving the graft while ensuring local control is a challenge we have faced in two occasions. We report our experience. MET...

    journal_title：Brachytherapy

    pub_type： 社论

    doi：10.1016/j.brachy.2013.11.003

    authors： Maroun P,Rivin E,Dumas I,Mondini M,Brahim J,Haie-Meder C,Mazeron R

    更新日期：2014-01-01 00:00:00

  • Combined modality treatment with high-dose-rate brachytherapy boost for locally advanced prostate cancer.

    abstract：PURPOSE:This is a retrospective review of our experience using high-dose-rate (HDR) brachytherapy boost for prostate cancer. METHODS AND MATERIALS:During the study period, we recommended external beam radiotherapy (45 Gy) and HDR boost (18 Gy in three fractions) combined with hormonal therapy (HT) for 2 months before ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2005.03.005

    authors： Hsu IC,Cabrera AR,Weinberg V,Speight J,Gottschalk AR,Roach M 3rd,Shinohara K

    更新日期：2005-01-01 00:00:00

  • Prospective evaluation of patient satisfaction after the use of brachytherapy specific educational materials for cervical cancer.

    abstract：BACKGROUND:Cervical cancer patients are faced with an enormous amount of medical information in a complex oncology field with sophisticated treatments including brachytherapy. We investigated the use of enhanced vs. standard brachytherapy-specific educational materials on patient-reported satisfaction during the inform...

    journal_title：Brachytherapy

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.brachy.2015.09.007

    authors： Rash D,Hess C,Lentz S,Tait L,Michaud A,Mayadev J

    更新日期：2016-01-01 00:00:00

  • Measuring relief of dysphagia in locally advanced esophageal carcinoma patients submitted to high-dose-rate brachytherapy.

    abstract：BACKGROUND AND PURPOSE:Esophageal neoplasm has a poor prognosis, and palliative care remains an important goal of treatment. The purpose of this study was to assess the ability of high-dose-rate brachytherapy (HDRB) to improve dysphagia in 115 patients treated at our institution. METHODS AND MATERIALS:Patients previou...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2014.09.007

    authors： Grazziotin Reisner R,Reisner ML,Ferreira MA,Rosa AA,Veras IM,Carneiro TM,Wolff B,Viégas CM,Mendonça de Araújo CM,Marchiori E

    更新日期：2015-01-01 00:00:00

  • Relationship between Day 0 dosimetric parameters and biochemical relapse-free survival in patients treated with transperineal permanent prostate interstitial brachytherapy with (125)I seeds.

    abstract：OBJECTIVES:To determine the relationship between dosimetric parameters obtained on postimplantation Day 0 and biochemical relapse-free survival (bRFS) in patients treated with (125)I transperineal interstitial permanent prostate brachytherapy (TIPPB). METHODS:Two-hundred twenty men with low-risk (n=155, 70.4%), low-vo...

    journal_title：Brachytherapy

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.brachy.2009.04.005

    authors： Garrán C,Ciérvide R,Cambeiro M,Moreno-Jiménez M,Ramos LI,Martínez-Monge R

    更新日期：2010-01-01 00:00:00

  • A unique approach to high-dose-rate vaginal mold brachytherapy of gynecologic malignancies.

    abstract：PURPOSE:Patients with cervical and vaginal cancer sometimes have a less straightforward approach for choice of brachytherapy treatment owing to the tumor's location and clinical presentation. The staff at Royal Brisbane & Women's Hospital in Queensland, Australia, is trying to solve this problem by the use of an old te...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2014.10.004

    authors： Nilsson S,Moutrie Z,Cheuk R,Chan P,Lancaster C,Markwell T,Dawes J,Back P

    更新日期：2015-03-01 00:00:00

  • Clinical outcomes of high-dose-rate brachytherapy and external beam radiotherapy in the management of clinically localized prostate cancer.

    abstract：PURPOSE:To report prostate-specific antigen (PSA) relapse-free survival and treatment-related toxicity outcomes after combining high-dose-rate (HDR) brachytherapy with external beam radiotherapy (EBRT) for patients with clinically localized prostate cancer. METHODS AND MATERIALS:Between 1998 and 2009, 229 patients wer...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2012.05.003

    authors： Kotecha R,Yamada Y,Pei X,Kollmeier MA,Cox B,Cohen GN,Zaider M,Zelefsky MJ

    更新日期：2013-01-01 00:00:00

  • Skin and chest wall dose with multi-catheter and MammoSite breast brachytherapy: Implications for late toxicity.

    abstract：PURPOSE:Accelerated partial breast irradiation (APBI) continues to increase in popularity. Up to 14% of patients treated with the MammoSite (MS) report some degree of chronic pain, which may be related to chest wall toxicity. Reports from several institutions using the multicatheter (MC) technique have not shown associ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2008.11.007

    authors： Cuttino LW,Todor D,Rosu M,Arthur DW

    更新日期：2009-04-01 00:00:00

  • Robustness to source displacement in dual air kerma strength planning for focal low-dose-rate brachytherapy of prostate cancer.

    abstract：PURPOSE:To describe the use of dual source strength implants for focal low-dose-rate brachytherapy. METHODS AND MATERIALS:An interneedle dual source strength planning strategy is described for focal low-dose-rate brachytherapy of the prostate. The implanted treatment plans were designed using peripheral (except near t...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2016.04.388

    authors： Mahdavi SS,Spadinger IT,Chng NT,Morris WJ

    更新日期：2016-09-01 00:00:00

  • Salvage wide resection with intraoperative electron beam therapy or HDR brachytherapy in the management of isolated local recurrences of soft tissue sarcomas of the extremities and the superficial trunk.

    abstract：PURPOSE:To assess the toxicity and efficacy of salvage wide resection (SWR) with intraoperative electron beam radiation therapy (IOERT) or perioperative high-dose-rate brachytherapy (PHDRB) in previously unirradiated patients (PUP) vs. previously irradiated patients (PIP) with isolated local recurrence of soft tissue s...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2014.09.003

    authors： Cambeiro M,Aristu JJ,Moreno Jimenez M,Arbea L,Ramos L,San Julian M,Azinovic I,Calvo FA,Martínez-Monge R

    更新日期：2015-01-01 00:00:00

  • Is stereotactic CyberKnife radiotherapy or multicatheter HDR brachytherapy the better option dosimetrically for accelerated partial breast irradiation?

    abstract：OBJECTIVE:To compare dosimetrically the stereotactic CyberKnife (CK) therapy and multicatheter high-dose-rate (HDR) brachytherapy (BT) for accelerated partial breast irradiation (APBI). METHODS:Treatment plans of 25 patients treated with CK were selected, and additional plans using multicatheter HDR BT were created on...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2020.10.003

    authors： Fröhlich G,Mészáros N,Smanykó V,Stelczer G,Herein A,Polgár C,Major T

    更新日期：2020-11-18 00:00:00

  • Measurement of dose perturbation around shielded ovoids in high-dose-rate brachytherapy.

    abstract：PURPOSE:To analyze the effect of tungsten shields present in a Fletcher-Suit-Delclos ovoid by comparing the dose distribution computed by a treatment planning system (TPS) to the delivered dose distribution measured by radiochromic film dosimetry. METHODS AND MATERIALS:Gafchromic/EBT films were carefully wrapped aroun...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2010.08.008

    authors： Hira M,Podgorsak MB,Jaggernauth W,Malhotra HK

    更新日期：2011-05-01 00:00:00

  • The effect of hormonal manipulation on urinary function following permanent prostate brachytherapy.

    abstract：PURPOSE:To evaluate the effect of hormonal manipulation on catheter dependency, the resolution of urinary symptomatology, and the need for postbrachytherapy transurethral/transincisional resection (TURP/TUIP). METHODS AND MATERIALS:Seven hundred sixteen consecutive patients (median follow-up, 29 months) underwent brac...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2003.12.001

    authors： Merrick GS,Butler WM,Wallner KE,Murray B,Allen Z,Lief JH,Galbreath RW

    更新日期：2004-01-01 00:00:00

  • High-dose-rate brachytherapy for localized penile cancer: Evolution of a technique.

    abstract：PURPOSE:High-dose-rate (HDR) brachytherapy is a convenient treatment option for selected patients with T1-T2 penile squamous cell carcinoma (SCC), providing high rates of penile preservation and tumor control. We present the results of penile SCC treated with HDR brachytherapy either interstitially or via a surface mol...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2019.12.003

    authors： Marbán M,Crook J,Keyes M,Dubash R,Batchelar D

    更新日期：2020-01-01 00:00:00

  • The feasibility of a second lumpectomy and breast brachytherapy for localized cancer in a breast previously treated with lumpectomy and radiation therapy for breast cancer.

    abstract：PURPOSE:With accumulating evidence supporting partial-breast irradiation, we conducted a Phase I/II study to evaluate the role of a second conservative surgery and brachytherapy for patients presenting with a local recurrence/new primary in a breast who has previously undergone a lumpectomy and external radiation thera...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2007.10.006

    authors： Chadha M,Feldman S,Boolbol S,Wang L,Harrison LB

    更新日期：2008-01-01 00:00:00

  • Development of an indigenous low-cost multichannel cylinder applicator for vaginal tumors.

    abstract：PURPOSE:The purpose of this study was to report our experience regarding the development of a low-cost multichannel vaginal cylinder applicator for superficial and recurrent vaginal tumors. METHODS AND MATERIALS:The applicator mold was created by applying heated wax sheets in layers around a plastic tube. Interstitial...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2020.05.001

    authors： Bajwa HK,Singareddy R,Talluri AK,Guntupalli R,Raju AK,Sresty M,Ahmed A

    更新日期：2020-01-01 00:00:00

  • High-dose-rate interstitial brachytherapy in recurrent and previously irradiated head and neck cancers--preliminary results.

    abstract：PURPOSE:Although high-dose-rate brachytherapy (HDRBT) offers significant advantages over low dose rate brachytherapy, there are scant data on improved local control (LC) and treatment-related complications in patients with recurrent head and neck (H&N) cancers. We report our preliminary results in patients with recurre...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2006.12.001

    authors： Narayana A,Cohen GN,Zaider M,Chan K,Lee N,Wong RJ,Boyle J,Shaha A,Kraus D,Shah J,Zelefsky MJ

    更新日期：2007-04-01 00:00:00

  • Permanent prostate brachytherapy and short-term androgen deprivation for intermediate-risk prostate cancer in Japanese men: outcome and toxicity.

    abstract：OBJECTIVES:To evaluate the interim outcomes of low-dose-rate permanent brachytherapy (PB) combined with short-term androgen deprivation therapy (ADT) in Japanese men with intermediate-risk prostate cancer excluding those with a Gleason score of 4+3. METHODS:The Protocol-intermediate-risk group (Protocol-IRG) was defin...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2014.09.001

    authors： Yamada Y,Masui K,Iwata T,Naitoh Y,Yamada K,Miki T,Okihara K

    更新日期：2015-03-01 00:00:00

  • Prostate-specific antigen bounce after curative brachytherapy for early-stage prostate cancer: A study of 274 African-Caribbean patients.

    abstract：BACKGROUND:Prostate cancer incidence in the African-Caribbean population ranks among the highest worldwide. We aim to evaluate the prostate-specific antigen (PSA) kinetics after brachytherapy, which so far remains unknown in this population. METHODS AND MATERIALS:From 2005 to 2013, 371 patients received (125)I brachyt...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2015.09.005

    authors： Leduc N,Atallah V,Creoff M,Rabia N,Taouil T,Escarmant P,Vinh-Hung V

    更新日期：2015-11-01 00:00:00

  • MRI-assisted radiosurgery: A quality assurance nomogram for palladium-103 and iodine-125 prostate brachytherapy.

    abstract：PURPOSE:We sought to develop an activity nomogram for magnetic resonance (MR)-planned permanent seed prostate brachytherapy to improve quality assurance through a secondary dosimetric check. METHODS AND MATERIALS:Patients undergoing MRI-assisted radiosurgery (MARS), whereby MRI is used for preoperative planning and po...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2019.10.002

    authors： Hanania AN,Kudchadker RJ,Bruno TL,Tang C,Anscher MS,Frank SJ

    更新日期：2020-01-01 00:00:00