Alterations of the Gut Microbiome Composition and Lipid Metabolic Profile in Radiation Enteritis.

abstract：:Pathogenic fungi have developed many strategies to evade the host immune system. Multiple escape mechanisms appear to function together to inhibit attack by the various stages of both the adaptive and the innate immune response. Thus, after entering the host, such pathogens fight to overcome the immune system to allow...

journal_title：Frontiers in cellular and infection microbiology

authors： Marcos CM,de Oliveira HC,de Melo WC,da Silva JF,Assato PA,Scorzoni L,Rossi SA,de Paula E Silva AC,Mendes-Giannini MJ,Fusco-Almeida AM

更新日期：2016-11-15 00:00:00

abstract：:An important component in host resistance to malaria infection are inherited mutations that give rise to abnormalities and deficiencies in erythrocyte proteins and enzymes. Understanding how such mutations confer protection against the disease may be useful for developing new treatment strategies. A mouse ENU-induced ...

journal_title：Frontiers in cellular and infection microbiology

authors： Schnider CB,Yang H,Starrs L,Ehmann A,Rahimi F,Di Pierro E,Graziadei G,Matthews K,De Koning-Ward T,Bauer DC,Foote SJ,Burgio G,McMorran BJ

更新日期：2020-09-03 00:00:00

abstract：:Transition metal ions are essential micronutrients for all living organisms. In mammals, these ions are often protein-bound and sequestered within cells, limiting their availability to microbes. Moreover, in response to infection, mammalian hosts further reduce the availability of metal nutrients by activating epithel...

journal_title：Frontiers in cellular and infection microbiology

authors： Diaz-Ochoa VE,Jellbauer S,Klaus S,Raffatellu M

更新日期：2014-01-24 00:00:00

abstract：:Campylobacter jejuni (CJ) is the most prevalent zoonotic pathogen of chicken meat and related products, which may lead to gastroenteritis and autoimmune diseases in humans. Although controlling this bacterium is important, CJ strains resistance against traditional antibiotic therapy has been increased. Vegetable oils ...

journal_title：Frontiers in cellular and infection microbiology

authors： Ribeiro LNM,de Paula E,Rossi DA,Martins FA,de Melo RT,Monteiro GP,Breitkreitz MC,Goulart LR,Fonseca BB

更新日期：2021-01-08 00:00:00

abstract：:The intracellular pathogen Burkholderia pseudomallei, the etiological agent of melioidosis in humans and various animals, is capable of survival and movement within the cytoplasm of host cells by a process known as actin-based motility. The bacterial factor BimA is required for actin-based motility through its direct ...

journal_title：Frontiers in cellular and infection microbiology

authors： Srinon V,Chaiwattanarungruengpaisan S,Korbsrisate S,Stevens JM

更新日期：2019-03-22 00:00:00

abstract：:Intracellular bacterial pathogens (IBPs) invade and replicate in different cell types including immune cells, in particular of the innate immune system (IIS) during infection in the acute phase. However, immune cells primarily function as essential players in the highly effective and integrated host defense systems co...

journal_title：Frontiers in cellular and infection microbiology

authors： Eisenreich W,Rudel T,Heesemann J,Goebel W

更新日期：2017-07-13 00:00:00

abstract：:Vaccination remains a major tool for prevention and progression of Johne's disease, a chronic enteritis of ruminants worldwide. Currently there is only one licensed vaccine within the United States and two vaccines licensed internationally against Johne's disease. All licensed vaccines reduce fecal shedding of Mycobac...

journal_title：Frontiers in cellular and infection microbiology

authors： Lamont EA,Talaat AM,Coussens PM,Bannantine JP,Grohn YT,Katani R,Li LL,Kapur V,Sreevatsan S

更新日期：2014-06-30 00:00:00

abstract：:Antifolate resistance is significant in Kenya and presumed to result from extensive use and cross-resistance between antifolate antimalarials and antibiotics, including cotrimoxazole/Bactrim used for HIV-1 chemotherapy. However, little is known about antifolate-resistant malaria in the context of newly diagnosed HIV-1...

journal_title：Frontiers in cellular and infection microbiology

authors： Torrevillas BK,Garrison SM,McKeeken AJ,Patel D,Van Leuven JT,Dizon NI,Rivas KI,Hathaway NJ,Bailey JA,Waitumbi JN,Kifude CM,Oyieko J,Stewart VA,Luckhart S

更新日期：2020-11-26 00:00:00

abstract：:Whole genome sequencing (WGS) methods provide new possibilities in the field of molecular epidemiology. This is particularly true for monomorphic organisms where the discriminatory power of traditional methods (e.g., restriction enzyme length polymorphism typing, multi locus sequence typing etc.) is inadequate to eluc...

journal_title：Frontiers in cellular and infection microbiology

authors： Wittwer M,Altpeter E,Pilo P,Gygli SM,Beuret C,Foucault F,Ackermann-Gäumann R,Karrer U,Jacob D,Grunow R,Schürch N

更新日期：2018-03-22 00:00:00

abstract：:Enterococcus faecium is a clinically important pathogen associated with opportunistic infection and multi-drug resistance. E. faecium has been shown to produce membrane vesicles (MVs), but MV production by E. faecium under antibiotic stress conditions and the pathogenic traits thereof have yet to be determined. This s...

journal_title：Frontiers in cellular and infection microbiology

authors： Kim MH,Kim SY,Son JH,Kim SI,Lee H,Kim S,Shin M,Lee JC

更新日期：2019-08-14 00:00:00

abstract：:Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host-pathogen interactions and identifying chief ...

journal_title：Frontiers in cellular and infection microbiology

authors： Younes S,Al-Sulaiti A,Nasser EAA,Najjar H,Kamareddine L

更新日期：2020-06-23 00:00:00

abstract：:Background: The pathogenesis of inflammatory bowel disease (IBD) is linked to an intricate association of environmental, microbial, and host-related factors. Polysaccharide affects host immunity by regulating the composition and metabolism of gut microbiota is the common mechanism of disease resistance. However, the e...

journal_title：Frontiers in cellular and infection microbiology

authors： Su L,Mao C,Wang X,Li L,Tong H,Mao J,Ji,Lu T,Hao M,Huang Z,Fei C,Zhang K,Yan G

更新日期：2020-10-21 00:00:00

abstract：:Staphylococcus aureus is the leading etiologic agent of orthopedic implant infections. Here a ribocluster of 27 S. aureus strains underwent further molecular characterization and subtyping by multilocus sequence typing (MLST) and spa-typing. This cluster had been detected by automated ribotyping (with the EcoRI restri...

journal_title：Frontiers in cellular and infection microbiology

authors： Montanaro L,Ravaioli S,Ruppitsch W,Campoccia D,Pietrocola G,Visai L,Speziale P,Allerberger F,Arciola CR

更新日期：2016-02-16 00:00:00

abstract：:Programmed cell death (PCD) can play a crucial role in tuning the immune response to microbial infection. Although PCD can occur in different forms, all are mediated by a family of proteases called caspases. Caspase-2 is the most conserved caspase, however, its function in cell death is ill-defined. Previously we demo...

journal_title：Frontiers in cellular and infection microbiology

authors： Bronner DN,O'Riordan MX,He Y

更新日期：2013-11-27 00:00:00

abstract：:Probiotics have been used to treat a variety of diseases for decades; however, what is the rationale for their application? Such a treatment was first proposed in the early nineteenth century based on observations of decreased bifidobacterial populations in children suffering from diarrhea, suggesting that oral intake...

journal_title：Frontiers in cellular and infection microbiology

authors： Wieërs G,Belkhir L,Enaud R,Leclercq S,Philippart de Foy JM,Dequenne I,de Timary P,Cani PD

更新日期：2020-01-15 00:00:00

abstract：:To discern if there was a particular genotype associated with clinical enteroaggregative Escherichia coli (EAEC) strains isolated from deployed military personnel (DMP) with travelers' diarrhea (TD), we characterized a collection of EAEC from DMP deployed to Afghanistan, Djibouti, Kenya, or Honduras. Although we did n...

journal_title：Frontiers in cellular and infection microbiology

authors： Petro CD,Duncan JK,Seldina YI,Allué-Guardia A,Eppinger M,Riddle MS,Tribble DR,Johnson RC,Dalgard CL,Sukumar G,Connor P,Boisen N,Melton-Celsa AR

更新日期：2020-05-20 00:00:00

abstract：:The phenylacetic acid (PA) degradative pathway is the central pathway by which various aromatic compounds (e.g., styrene) are degraded. Upper pathways for different aromatic compounds converge at common intermediate phenylacetyl-CoA (PA-CoA), which is then metabolized to succinyl-CoA and acetyl-CoA. We previously made...

journal_title：Frontiers in cellular and infection microbiology

authors： Imolorhe IA,Cardona ST

更新日期：2011-12-14 00:00:00

abstract：:For centuries, hydrogen sulfide (H2S) was considered primarily as a poisonous gas and environmental hazard. However, with the discovery of prokaryotic and eukaryotic enzymes for H2S production, breakdown, and utilization, H2S has emerged as an important signaling molecule in a wide range of physiological and pathologi...

journal_title：Frontiers in cellular and infection microbiology

authors： Rahman MA,Glasgow JN,Nadeem S,Reddy VP,Sevalkar RR,Lancaster JR Jr,Steyn AJC

更新日期：2020-11-10 00:00:00

abstract：:While microbiome plays key roles in the etiology of multiple sclerosis (MS), its mechanism remains elusive. Here, we conducted a comprehensive metagenome-wide association study (MWAS) of the relapsing-remitting MS gut microbiome (ncase = 26, ncontrol = 77) in the Japanese population, by using whole-genome shotgun sequ...

journal_title：Frontiers in cellular and infection microbiology

authors： Kishikawa T,Ogawa K,Motooka D,Hosokawa A,Kinoshita M,Suzuki K,Yamamoto K,Masuda T,Matsumoto Y,Nii T,Maeda Y,Nakamura S,Inohara H,Mochizuki H,Okuno T,Okada Y

更新日期：2020-12-11 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) O157:H7 EspF is an important multifunctional protein that destroys the tight junctions of intestinal epithelial cells and promotes host cell apoptosis. However, its molecular mechanism remains elusive. We knocked out the espF sequence (747 bp, ΔespF), N-terminal sequence (219 ...

journal_title：Frontiers in cellular and infection microbiology

authors： Wang X,Du Y,Hua Y,Fu M,Niu C,Zhang B,Zhao W,Zhang Q,Wan C

更新日期：2017-09-21 00:00:00

abstract：:Visceral leishmaniasis is a neglected tropical disease caused by Leishmania (L.) donovani parasite in the Indian subcontinent. Macrophages (mϕ) are the harboring cells for parasite and their interactions dictate the pathogenesis of this disease. Polyunsaturated fatty acids are an integral part of the mϕ cell membrane ...

journal_title：Frontiers in cellular and infection microbiology

authors： Saini S,Rai AK

更新日期：2020-08-07 00:00:00

abstract：:The Asian tiger mosquito Aedes (Stegomya) albopictus is an invasive species that has spread across the world in the last two decades, showing a great capacity to adapt to contrasting climates and environments. While demonstrated in many insects, the contribution of bacterial symbionts in Aedes ecology is a challenging...

journal_title：Frontiers in cellular and infection microbiology

authors： Minard G,Tran FH,Dubost A,Tran-Van V,Mavingui P,Moro CV

更新日期：2014-05-14 00:00:00

abstract：:The intracellular parasite Toxoplasma gondii can cause chronic infections in most warm-blooded animals, including humans. In the USA, strains belonging to four different Toxoplasma clonal lineages (types 1, 2, 3, and 12) are commonly isolated, whereas strains not belonging to these lineages are predominant in other co...

journal_title：Frontiers in cellular and infection microbiology

authors： Arranz-Solís D,Cordeiro C,Young LH,Dardé ML,Commodaro AG,Grigg ME,Saeij JPJ

更新日期：2019-11-29 00:00:00

abstract：:Objectives: The emergence of carbapenem-resistant Enterobacteriaceae, especially Klebsiella pneumoniae, has become a major concern in clinic settings. Combination therapy is gaining momentum to counter the secondary resistance and potential suboptimal efficacy of monotherapy. The aim of this study was to evaluate the ...

journal_title：Frontiers in cellular and infection microbiology

authors： Yu W,Zhou K,Guo L,Ji J,Niu T,Xiao T,Shen P,Xiao Y

更新日期：2017-06-16 00:00:00

abstract：:The mechanism by which microRNAs (miRNAs) modulate innate immunity and autophagy has not been fully elucidated in Mycobacterium bovis (M. bovis) infections. In this study, we identified that miR-199a inhibited key innate immune responses and autophagy in murine macrophages infected with M. bovis. Using ex vivo and in ...

journal_title：Frontiers in cellular and infection microbiology

authors： Wang J,Hussain T,Yue R,Liao Y,Li Q,Yao J,Song Y,Sun X,Wang N,Xu L,Sreevatsan S,Zhao D,Zhou X

更新日期：2018-07-10 00:00:00

abstract：:Prompt and effective elicitation of protective immunity is highly relevant for cases of rapidly deteriorating fatal diseases, such as plague, which is caused by Yersinia pestis. Here, we assessed the potential of a live vaccine to induce rapid protection against this infection. We demonstrated that the Y. pestis EV76 ...

journal_title：Frontiers in cellular and infection microbiology

authors： Zauberman A,Vagima Y,Tidhar A,Aftalion M,Gur D,Rotem S,Chitlaru T,Levy Y,Mamroud E

更新日期：2017-06-21 00:00:00

abstract：:Burkholderia pseudomallei is the causative agent of melioidosis, a rare disease of biodefense concern with high mortality and extreme difficulty in treatment. No human vaccines are available that protect against B. pseudomallei infection, and with the current limitations of antibiotic treatment, the development of new...

journal_title：Frontiers in cellular and infection microbiology

authors： Van Zandt KE,Tuanyok A,Keim PS,Warren RL,Gelhaus HC

更新日期：2012-09-26 00:00:00

abstract：:Cytokinesis, or the division of the cytoplasm, following the end of mitosis or meiosis, is accomplished in animal cells, fungi, and amoebae, by the constriction of an actomyosin contractile ring, comprising filamentous actin, myosin II, and associated proteins. However, despite this being the best-studied mode of cyto...

journal_title：Frontiers in cellular and infection microbiology

authors： Hammarton TC

更新日期：2019-11-21 00:00:00

abstract：:Shiga toxin (Stx)-producing Escherichia coli (STEC) O157:H7 is an enteric pathogen that causes life-threatening disease in humans, with cattle being major natural reservoirs. A group of STEC O157:H7 with a dramatic combination of high virulence potentials and super-shedder bovine origin have been isolated. Here, an ST...

journal_title：Frontiers in cellular and infection microbiology

authors： Teng L,Lee S,Park D,Jeong KC

更新日期：2020-06-05 00:00:00

abstract：:Programmed cell death plays crucial roles in organismal development and host defense. Recent studies have highlighted mechanistic overlaps and extensive, multifaceted crosstalk between pyroptosis, apoptosis, and necroptosis, three programmed cell death pathways traditionally considered autonomous. The growing body of ...

journal_title：Frontiers in cellular and infection microbiology

authors： Christgen S,Zheng M,Kesavardhana S,Karki R,Malireddi RKS,Banoth B,Place DE,Briard B,Sharma BR,Tuladhar S,Samir P,Burton A,Kanneganti TD

更新日期：2020-05-29 00:00:00