Abstract:
:Patterns of functional connectivity are unique at the individual level, enabling test-retest matching algorithms to identify a subject from among a group using only their functional connectome. Recent findings show that accuracies of these algorithms in children increase with age. Relatedly, the persistence of functional connectivity (FC) patterns across tasks and rest also increases with age. This study investigated the hypothesis that within-subject stability and between-subject similarity of the whole-brain pediatric connectome are developmentally relevant outcomes. Using data from 210 help-seeking children and adolescents, ages 6-21 years (Healthy Brain Network Biobank), we computed whole-brain FC matrices for each participant during two different movies (MovieDM and MovieTP) and two runs of task-free rest (all from a single scan session) and fed these matrices to a test-retest matching algorithm. We replicated the finding that matching accuracies for children and youth (ages 6-21 years) are low (18-44%), and that cross-state and cross-movie accuracies were the lowest. Results also showed that parcellation resolution and the number of volumes used in each matrix affect fingerprinting accuracies. Next, we calculated three measures of whole-connectome stability for each subject: cross-rest (Rest1-Rest2), cross-state (MovieDM-Rest1), and cross-movie (MovieDM-MovieTP), and three measures of within-state between-subject connectome similarity for Rest1, MovieDM, and MovieTP. We show that stability and similarity were correlated, but that these measures were not related to age. A principal component analysis of these measures yielded two components that we used to test for brain-behavior correlations with IQ, general psychopathology, and social skills measures (n = 119). The first component was significantly correlated with the social skills measure (r=-0.26, p = 0.005). Post hoc correlations showed that the social skills measure correlated with both cross-rest stability (r=-0.29, p = 0.001) and with connectome similarity during MovieDM (r=-0.28, p = 0.002). These findings suggest that the stability and similarity of the whole-brain connectome relate to the development of social skills. We infer that the maturation of the functional connectome simultaneously achieves patterns of FC that are distinct at the individual subject level, that are shared across individuals, and that are persistent across states and across runs-features which presumably combine to optimize neural processing during development. Future longitudinal work could reveal the developmental trajectories of stability and similarity of the connectome.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Vanderwal T,Eilbott J,Kelly C,Frew SR,Woodward TS,Milham MP,Castellanos FXdoi
10.1016/j.neuroimage.2020.117537subject
Has Abstractpub_date
2021-02-01 00:00:00pages
117537eissn
1053-8119issn
1095-9572pii
S1053-8119(20)31022-3journal_volume
226pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::Group independent component analysis (ICA) has been widely applied to studies of multi-subject fMRI data for computing subject specific independent components with correspondence across subjects. However, the independence of subject specific independent components (ICs) derived from group ICA has not been explicitly o...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.11.008
更新日期:2013-04-01 00:00:00
abstract::The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for speed of signal conduction, cellular energetics, and spatial constraints. In vivo imaging of the g-ratio in health and disease woul...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2017.08.038
更新日期:2018-11-15 00:00:00
abstract::Noise-normalization has been shown to partly compensate for the localization bias towards superficial sources in minimum norm estimation. However, it has been argued that in order to make inferences for the case of multiple sources, localization properties alone are insufficient. Instead, multiple measures of resoluti...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.09.053
更新日期:2011-02-01 00:00:00
abstract::The ability to imagine the world from a different viewpoint is a fundamental competence for spatial reorientation and for imagining what another individual sees in the environment. Here, we investigated the neural bases of such an ability using functional magnetic resonance imaging. Healthy participants detected targe...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.10.040
更新日期:2016-01-15 00:00:00
abstract::A well-recognized problem with the echo-planar imaging (EPI) technique most commonly used for functional magnetic resonance imaging (fMRI) studies is geometric distortion caused by magnetic field inhomogeneity. This makes it difficult to achieve an accurate registration between a functional activation map calculated f...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.1054
更新日期:2002-05-01 00:00:00
abstract::The purpose of this study was to identify brain regions underlying internally generated anticipatory biases toward locations where significant events are expected to occur. Subjects fixated centrally and responded to peripheral targets preceded by a spatially valid (predictive), invalid (misleading), or neutral centra...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/s1053-8119(02)00012-5
更新日期:2003-03-01 00:00:00
abstract::The diffusion tensor is a commonly used model for diffusion-weighted MR image data. The parameters are typically estimated by ordinary or weighted least squares on log-transformed data, assuming normal or log-normal distribution of measurement errors respectively. This may not be adequate when using high b-values and ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.05.053
更新日期:2008-10-01 00:00:00
abstract::This study examined within-subject differences among three fluid abilities that decline with age: reasoning, episodic memory and processing speed, compared with vocabulary, a crystallized ability that is maintained with age. The data were obtained from the Reference Ability Neural Network (RANN) study from which 221 p...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116809
更新日期:2020-07-15 00:00:00
abstract::Inhibitory control of actions is one important aspect in daily life to warrant adequate context related behavior. Alpha activity (oscillatory brain activity around 10Hz) has been suggested to play a major role for the implementation of inhibitory control. In the present study electrophysiological correlates of volunta...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.09.048
更新日期:2013-01-15 00:00:00
abstract::Imaging biomarkers derived from magnetic resonance imaging (MRI) data are used to quantify normal development, disease, and the effects of disease-modifying therapies. However, motion during image acquisition introduces image artifacts that, in turn, affect derived markers. A systematic effect can be problematic since...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.12.006
更新日期:2015-02-15 00:00:00
abstract::Transcranial color coded sonography has proved valuable in the diagnostic work-up of cerebrovascular disorders in adults. More recently, evidences have converged that transcranial sonography is also useful in the diagnosis of brain parenchymal disorders. Here, a new field of application is the visualization of signal ...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1006/nimg.2001.1014
更新日期:2002-03-01 00:00:00
abstract::Orientation selectivity is a fundamental property of neurons in the visual cortex for form perception. Cortical cells with similar preferred orientations are organized in a columnar manner to form a two-dimensional orientation map in the primary visual cortex (area 17). There are several mechanisms underlying the gene...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.12.014
更新日期:2008-04-01 00:00:00
abstract::Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by progressive behavioural abnormalities and frontotemporal atrophy. Here we used tensor based morphometry (TBM) to identify regions of longitudinal progression of gray matter atrophy in FTD compared to controls. T1-weighted MRI images were acq...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.01.028
更新日期:2007-04-15 00:00:00
abstract::Sleep spindles are crucial to memory consolidation. Cortical gamma oscillations (30-100 Hz) are considered to reflect processing of memory in local cortical networks. The temporal and regulatory relationship between spindles and gamma activity might therefore provide clues into how sleep strengthens cortical memory re...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117452
更新日期:2021-01-01 00:00:00
abstract::Using the ER-fMRI technique, the present study was designed to investigate the neural substrates of language switching among second-language learners. Twelve Chinese college students who were learning English were scanned when they performed language switching tasks (naming pictures in their first [L1, Chinese] and se...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.09.054
更新日期:2007-04-01 00:00:00
abstract::Spontaneous activity of the brain at rest frequently has been considered a mere backdrop to the salient activity evoked by external stimuli or tasks. However, the resting state of the brain consumes most of its energy budget, which suggests a far more important role. An intriguing hint comes from experimental observat...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.024
更新日期:2013-02-01 00:00:00
abstract::Psychologists have been trying to understand differences in cognition and behavior between East Asian and Western cultures within a single cognitive framework such as holistic versus analytic or interdependent versus independent processes. However, it remains unclear whether cultural differences in multiple psychologi...
journal_title:NeuroImage
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.neuroimage.2014.05.062
更新日期:2014-10-01 00:00:00
abstract::Functional lateralization is a feature of human brain function, most apparent in the typical left-hemisphere specialization for language. A number of anatomical and imaging studies have examined whether structural asymmetries underlie this functional lateralization. We combined functional MRI (fMRI) and diffusion-weig...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.03.011
更新日期:2006-08-01 00:00:00
abstract::Healthy aging is marked by declines in a variety of cognitive and motor abilities. A better understanding of the aging brain may aid in elucidating the neural substrates of these behavioral effects. Investigations of resting state functional brain connectivity have provided insights into pathology, and to some degree,...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.06.042
更新日期:2013-12-01 00:00:00
abstract::The key idea of statistical hypothesis testing is to fix, and thereby control, the Type I error (false positive) rate across samples of any size. Multiple comparisons inflate the global (family-wise) Type I error rate and the traditional solution to maintaining control of the error rate is to increase the local (compa...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.08.009
更新日期:2015-12-01 00:00:00
abstract::In the past several years, the number of studies investigating enhancement of cognitive functions through noninvasive brain stimulation (NBS) has increased considerably. NBS techniques, such as transcranial magnetic stimulation and transcranial current stimulation, seem capable of enhancing cognitive functions in pati...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2013.07.038
更新日期:2014-01-15 00:00:00
abstract::In sentence processing, storage and ordering of the verb and its arguments (subject and object) are core tasks. Their cortical representation is a matter of ongoing debate, and it is unclear whether prefrontal activations in neuroimaging studies on sentence processing reflect the storage of arguments or their ordering...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.05.052
更新日期:2012-09-01 00:00:00
abstract::Analysis of fMRI time series is often performed by extracting one or more parameters for the individual voxels. Methods based, e.g., on various statistical tests are then used to yield parameters corresponding to probability of activation or activation strength. However, these methods do not indicate whether sets of v...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0391
更新日期:1999-03-01 00:00:00
abstract::We evaluated the source distribution of benign rolandic spikes of childhood along and across the central sulcus in 15 patients, aged between 7 and 15 years, who suffered from seizure disorders. Previous routine EEG showed centrotemporal spikes, but none of them had major abnormalities on brain magnetic resonance imagi...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.11.040
更新日期:2005-04-01 00:00:00
abstract::High frequency brain oscillations are associated with numerous cognitive and behavioral processes. Non-invasive measurements using electro-/magnetoencephalography (EEG/MEG) have revealed that high frequency neural signals are heritable and manifest changes with age as well as in neuropsychiatric illnesses. Despite the...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.05.006
更新日期:2016-08-15 00:00:00
abstract::In the current study, electroencephalography (EEG) was recorded simultaneously with facial electromyography (fEMG) to determine whether emotional faces and emotional scenes are processed differently at the neural level. In addition, it was investigated whether these differences can be observed at the behavioural level...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.09.065
更新日期:2016-01-01 00:00:00
abstract::Efficient encoding of relevant information and suppression of irrelevant information influence working memory (WM) performance, which is limited and declines in adulthood. A cued Sternberg WM task and electroencephalographic recordings (EEG) were used to investigate encoding and control operations in response to to-be...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.11.071
更新日期:2012-03-01 00:00:00
abstract::We proposed ICA-AROMA as a strategy for the removal of motion-related artifacts from fMRI data (Pruim et al., 2015). ICA-AROMA automatically identifies and subsequently removes data-driven derived components that represent motion-related artifacts. Here we present an extensive evaluation of ICA-AROMA by comparing our ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.02.063
更新日期:2015-05-15 00:00:00
abstract::The primary visual cortex of humans contains patches of neurons responding preferentially to stimulation of one eye (the ocular dominance columns). Multiple previous studies attempted to detect their activity using fMRI. The majority of these fMRI studies used magnetic field strengths of 4 T and higher. However, ther...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117078
更新日期:2020-10-15 00:00:00
abstract::The aim of this study was to define the mean regional 6-[(18)F]fluoro-l-dopa (FDOPA) uptake rate constant (K(i)) values in the striatal and extrastriatal regions of the brain of normal subjects using magnetic resonance imaging (MRI)-aided spatial normalization of the FDOPA K(i) image and using automatic region of inte...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0584
更新日期:2000-06-01 00:00:00