A new perspective towards failure of gamma nail systems.

abstract：:In this review, we explored the progress of the pathogenesis of Kümmell's disease intravertebral vacuum. Using different expressions of the same disease including 'Kümmell's disease', 'avascular necrosis after vertebral compression fracture (VCF)', 'post-traumatic vertebral osteonecrosis', 'vertebral pseudarthrosis', ...

journal_title：Experimental and therapeutic medicine

authors： He D,Yu W,Chen Z,Li L,Zhu K,Fan S

更新日期：2016-08-01 00:00:00

abstract：:Resveratrol, a naturally occurring polyphenolic phytoalexin antioxidant compound present in grapes and red wine, has been reported to induce various biochemical responses. It has been shown to possess anti-aging, anti-inflammatory and anti-proliferative activities in several cell types. However, the effects of resvera...

journal_title：Experimental and therapeutic medicine

authors： Eo SH,Cho HS,Kim SJ

更新日期：2014-03-01 00:00:00

abstract：:The aim of this study was to compare the results of immunohistochemistry (IHC) assays evaluated by human examiners with the results evaluated by computerized image analysis, and to compare the computerized image analysis results among three automated IHC assays, namely the BioGenex, Dako and Ventana assays. All slides...

journal_title：Experimental and therapeutic medicine

authors： Arihiro K,Oda M,Ogawa K,Tominaga K,Kaneko Y,Shimizu T,Ohnishi S,Oda M,Kurita Y,Taira Y,Fujii M,Tanaka M

更新日期：2010-11-01 00:00:00

abstract：:The purpose of this study was to compare the results of delivering low doses of growth factor iteratively (20 μg x5) via a reservoir system with results obtained following a single administration of 100 μg of growth factor. The delivery systems using gelatin microspheres (GMS) facilitate the controlled release of drug...

journal_title：Experimental and therapeutic medicine

authors： Nitta N,Nitta-Seko A,Sonoda A,Watanabe S,Tsuchiya K,Murata K,Tabata Y

更新日期：2012-08-01 00:00:00

abstract：:The present study was an open-label, prospective, uncontrolled and multicenter clinical trial to investigate the safety and effectiveness of bevacizumab (Lumiere®) administered by the intravitreal route for the treatment of neovascular age-related macular degeneration (nAMD). A total of 22 patients without previous tr...

journal_title：Experimental and therapeutic medicine

authors： Benisek DA,Manzitti J,Scorsetti D,Rousselot Ascarza AM,Ascarza AA,Gomez Rancaño D,Quercia R,Ramirez Gismondi M,Carpio Total MA,Scorsetti ML,Spitzer E,Lombas C,Deprati M,Penna MI,Fernández F,Tinelli MA

更新日期：2020-12-01 00:00:00

abstract：:Lung adenocarcinoma (LACA) is the leading cause of cancer-associated death worldwide. The present study intended to identify DNA methylation patterns that may serve as diagnostic and prognostic biomarkers for LACA. Data on DNA methylation and the survival data of the patients of LACA were obtained from The Cancer Geno...

journal_title：Experimental and therapeutic medicine

authors： Zheng R,Xu H,Mao W,Du Z,Wang M,Hu M,Gu X

更新日期：2020-01-01 00:00:00

abstract：:Collecting duct carcinoma (CDC), which is also known as Bellini duct carcinoma, accounts for less than 1% of all renal cell carcinoma, which has a poor prognosis. Predominantly, clinicians recognize this disease due to past experience and case reports, and a standard treatment is yet to be established. The present cas...

journal_title：Experimental and therapeutic medicine

authors： Zhu L,Wang Z,Pan C,Peng R,Wei X,Zhong Z

更新日期：2016-08-01 00:00:00

abstract：:Insulin is used in the treatment of type 2 diabetes, with its usage reaching 30-50% in Western countries. The aim of the present study was to determine the association between insulin dosage (ID)/insulin usage time (IT) and coronary artery lesions in patients of type 2 diabetes with coronary heart disease. Based on th...

journal_title：Experimental and therapeutic medicine

authors： Luo XL,Yan QK,Wang Y,Fang H,Wang HY,Bai Y,Zeng CY,Wang XK

更新日期：2016-05-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) serve important roles in colorectal cancer. The aim of the present study was to investigate the expression and role of cervical carcinoma expressed PCNA regulatory (CCEPR) lncRNA in colorectal cancer progression. The results demonstrated that CCEPR expression was significantly higher in ...

journal_title：Experimental and therapeutic medicine

authors： Duan Y,Fang Z,Shi Z,Zhang L

更新日期：2019-11-01 00:00:00

abstract：:The diagnostic criteria of osteoporosis were established based on bone mineral density (BMD). Therefore, BMD measured by dual energy X-ray absorptiometry has been recognized as the gold standard to diagnose osteoporosis. However, discrepancies between fracture risk and BMD have been recognized. Bone is composed of col...

journal_title：Experimental and therapeutic medicine

authors： Suzuki Y,Maruyama-Nagao A,Sakuraba K,Kawai S

更新日期：2017-05-01 00:00:00

abstract：:The aim of the present study was to examine the effects of atorvastatinon p38 phosphorylation and cardiac remodeling after myocardial infarction in rats. A total of 43 rats were randomly divided into the control, sham operation, post-modeling medication (medication) and post-modeling non-medication (non-medication) gr...

journal_title：Experimental and therapeutic medicine

authors： Li M,Liu F,Sang M,Sun X,Li L,Wang X

更新日期：2018-08-01 00:00:00

abstract：:On December 31, 2019, the first case of a novel coronavirus infection was reported in Wuhan, China. The ongoing outbreak of the 2019 novel coronavirus (2019-nCoV) has caused immense global concern. According to the recommendations of the International Health Regulations Emergency Committee and the facts and cases that...

journal_title：Experimental and therapeutic medicine

authors： Feng X,Xie X,Song S,Chen W,Bian H,Rui F,Zhu Q,Ren W,Qin C,Qi J

更新日期：2021-01-01 00:00:00

abstract：:We investigated the clinical value of fractional flow reserve (FFR) for the prognostic evaluation of patients with percutaneous coronary intervention. We enrolled 120 patients who were admitted to the hospital to undergo percutaneous coronary intervention for acute coronary syndromes between May 2014 and June 2015. Th...

journal_title：Experimental and therapeutic medicine

authors： Zhao Q,Ji Z,Li X,Di Y,An H,Wei B,Yang L,Chen W

更新日期：2018-01-01 00:00:00

abstract：:Environmental exposure, including a high-fat diet (HFD), contributes to the high prevalence of colorectal cancer by changing the composition of the intestinal microbiota. However, data examining the interaction between dietary habits and intestinal microbiota of the Chinese population is sparse. We assessed dietary ha...

journal_title：Experimental and therapeutic medicine

authors： Qian L,Gao R,Hong L,Pan C,Li H,Huang J,Qin H

更新日期：2018-08-01 00:00:00

abstract：:The aim of this study was to determine the metabolic biomarkers for abnormal Savda syndrome in patients with chronic obstructive pulmonary disease (COPD). Based on Traditional Uyghur Medicine (TUM) theory, a total of 103 patients with COPD were classified into abnormal Savda and non-abnormal Savda syndrome groups and ...

journal_title：Experimental and therapeutic medicine

authors： Xu WF,Upur H,Wu YH,Mamtimin B,Yang J,Ga YJ,You L

更新日期：2015-02-01 00:00:00

abstract：:The alleviation of brain injury is a key issue following cardiopulmonary resuscitation (CPR). Hydrogen sulfide (H2S) is hypothesized to be involved in the pathophysiological process of ischemia-reperfusion injury, and exerts a protective effect on neurons. The aim of the present study was to investigate the effects of...

journal_title：Experimental and therapeutic medicine

authors： Lin JY,Zhang MW,Wang JG,Li H,Wei HY,Liu R,Dai G,Liao XX

更新日期：2016-02-01 00:00:00

abstract：:Inflammatory diseases are an important health concern and have a growing incidence worldwide. Thus, developing novel and safe drugs to treat these disorders remains an important pursuit. Artemisia iwayomogi, locally known as Dowijigi (DJ), is a perennial herb found primarily in Korea and is used to treat various disea...

journal_title：Experimental and therapeutic medicine

authors： Kim SM,Vetrivel P,Kim HH,Ha SE,Saralamma VVG,Kim GS

更新日期：2020-03-01 00:00:00

abstract：:While previous trials have indicated that the use of corticosteroids for patients with acute respiratory distress syndrome (ARDS) is effective, the dosage and time-course for the use of corticosteroids remain a subject of controversy. The present study aimed to address and resolve these problems. PubMed, Embase and th...

journal_title：Experimental and therapeutic medicine

authors： Sun S,Liu D,Zhang H,Zhang X,Wan B

更新日期：2019-12-01 00:00:00

abstract：:The present study aimed to evaluate the clinical efficacy of hyperbaric oxygen (HBO) treatment for depression in the convalescent stage following cerebral hemorrhage. A total of 60 cases of patients with depression in the convalescent stage following cerebral hemorrhage (2-6 months) were randomly divided into the trea...

journal_title：Experimental and therapeutic medicine

authors： Cao H,Ju K,Zhong L,Meng T

更新日期：2013-06-01 00:00:00

abstract：:In the present study, we demonstrate that the degeneration of intervertebral discs is caused by ageing and apoptosis of matrix cells. Apoptosis is as essential as the function of proteoglycan synthesis in assessing the possible degeneration of intervertebral discs; paeoniflorin (PF) induces cytoprotective effects on v...

journal_title：Experimental and therapeutic medicine

authors： Chen SQ,Lin JP,Zheng QK,Chen SJ,Li M,Lin XZ,Wang SZ

更新日期：2015-12-01 00:00:00

abstract：:The US Food and Drug Administration approved thalidomide and its analogues for the treatment of erythema nodosum leprosum, in spite of the notoriety of reports of severe birth defects in the middle of the last century. As immunomodulatory drugs, thalidomide and its analogues have been used to effectively treat various...

journal_title：Experimental and therapeutic medicine

authors： Liu T,Guo F,Zhu X,He X,Xie L

更新日期：2017-12-01 00:00:00

abstract：:Human serum albumin (HSA) is a transporting protein that has multiple functions. The binding interaction between HSA and small molecules affects its function and efficacy of small molecules. The present study reports that kaempferol-7-O-α-L-rhamnopyranoside (KR) interacts with HSA as indicated by multiple fluorescence...

journal_title：Experimental and therapeutic medicine

authors： Zhang W,Chen C,Zhang C,Duan J,Yao H,Li Y,Meng A,Shi J

更新日期：2017-06-01 00:00:00

abstract：:Abnormalities in insulin hormone levels leads to a hyperglycemic condition of diabetic mellitus. Hyperglycemia seriously induces organ and system destructions. The excessive accumulation of collagen fiber deposits occurs in inflammatory and reorganization processes of chronic liver diseases in type I insulin-dependent...

journal_title：Experimental and therapeutic medicine

authors： Komolkriengkrai M,Nopparat J,Vongvatcharanon U,Anupunpisit V,Khimmaktong W

更新日期：2019-08-01 00:00:00

abstract：:The aim of the present study was to evaluate whether preoperative computed tomography (CT) is a useful modality for the diagnosis of axillary lymph node metastasis. The axillary lymph node status was examined in patients with primary breast cancer who had undergone surgery. In total, 75 patients were analyzed with pre...

journal_title：Experimental and therapeutic medicine

authors： Kutomi G,Ohmura T,Satomi F,Takamaru T,Shima H,Suzuki Y,Otokozawa S,Zembutsu H,Mori M,Hirata K

更新日期：2014-08-01 00:00:00

abstract：:Immunomodulatory or immunosuppressive properties of bone marrow-derived mesenchymal stem cells (BM-MSCs) facilitate the treatment of acute respiratory distress syndrome and acute lung injury (ALI). Dysregulated miRNA (miRNA or miR) expression associated with the effects of BM-MSCs was assessed in a rat model of lipopo...

journal_title：Experimental and therapeutic medicine

authors： Park J,Jeong S,Park K,Yang K,Shin S

更新日期：2018-06-01 00:00:00

abstract：:The present study aimed to evaluate the prognostic value of venous-arterial CO2 to arterial-venous O2 (Cv-aCO2/Da-vO2) for patients with septic shock treated by fluid resuscitation. A total of 108 cases who received fluid resuscitation for septic shock at the Intensive Care Unit were retrospectively screened according...

journal_title：Experimental and therapeutic medicine

authors： Zang H,Shen X,Wang S,He Z,Cheng H

更新日期：2019-11-01 00:00:00

abstract：:The aim of the present study was to examine the effect of CCAAT enhancer binding protein β (C/EBPβ) on human breast cancer cells. The plasmids pCDH-C/EBPβ and pLKO.1-shC/EBPβ were constructed and were infected into MDA-MB-468 cells, to provide C/EBPβ overexpressing and C/EBPβ knockdown cells, respectively. Cell viabil...

journal_title：Experimental and therapeutic medicine

authors： Cao J,Wang M,Wang T

更新日期：2017-08-01 00:00:00

abstract：:Impaired insulin secretion and insulin resistance are the primary characteristics of type 2 diabetes (T2D). However, the mechanisms underlying insulin secretion failure have yet to be elucidated. The present study demonstrated that sirtuin 5 (SIRT5) is upregulated in patients with T2D and in pancreatic β-cell lines. I...

journal_title：Experimental and therapeutic medicine

authors： Ma Y,Fei X

更新日期：2018-08-01 00:00:00

abstract：:Cisplatin (DDP) is a commonly used chemotherapy drug; however, the side effects associated with its use, particularly acute kidney injury (AKI), limit its clinical application. Puerarin is a natural flavonoid extracted from the Chinese medical herb Radix puerariae, which has been reported to alleviate DDP-induced neph...

journal_title：Experimental and therapeutic medicine

authors： Wu Z,Li C,Li Q,Li J,Lu X

更新日期：2020-10-01 00:00:00

abstract：:Flos Chrysanthemi Indici (CI) is a traditional medicinal plant used in the treatment of inflammatory diseases. However, the pharmacological role of CI in metabolic diseases, especially in diseases induced by insulin metabolism disorders, remains poorly understood. In the present study, Drosophila melanogaster (Drosoph...

journal_title：Experimental and therapeutic medicine

authors： Bai Y,Li K,Shao J,Luo Q,Jin LH

更新日期：2018-09-01 00:00:00