Chemical composition, nutritional profile and in vivo antioxidant properties of the cultivated mushroom Coprinus comatus.

Abstract:

:This study investigated the chemical and nutritional profile and antioxidative properties of cultivated Coprinus comatus. Proximate analysis revealed that C. comatus is rich in carbohydrates, dietary fibres and proteins, and could also be a valuable source of phenolics. Additionally, fat content is low, consisting mainly of polyunsaturated and omega-3 fatty acids. Furthermore, the safety profile of C. comatus is satisfactory, with all elements of toxicological importance within the proposed limits. Oral treatment with C. comatus for 42 days improved the antioxidant capabilities and ameliorated carbon tetrachloride-induced liver damage in rats, marked by decreased serum aminotransferase levels and lipid peroxidation intensity. Glutathione concentrations increased in a dose-dependent manner. Histological morphometric and immunohistochemical analysis confirmed antioxidative and hepatoprotective potential. These findings imply that cultivated C.comatus could be considered a nutraceutical, having beneficial nutrient and therapeutic properties.

journal_name

R Soc Open Sci

authors

Stilinović N,Čapo I,Vukmirović S,Rašković A,Tomas A,Popović M,Sabo A

doi

10.1098/rsos.200900

subject

Has Abstract

pub_date

2020-09-02 00:00:00

pages

200900

issue

9

issn

2054-5703

pii

rsos200900

journal_volume

7

pub_type

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