Abstract:
:This study investigated the chemical and nutritional profile and antioxidative properties of cultivated Coprinus comatus. Proximate analysis revealed that C. comatus is rich in carbohydrates, dietary fibres and proteins, and could also be a valuable source of phenolics. Additionally, fat content is low, consisting mainly of polyunsaturated and omega-3 fatty acids. Furthermore, the safety profile of C. comatus is satisfactory, with all elements of toxicological importance within the proposed limits. Oral treatment with C. comatus for 42 days improved the antioxidant capabilities and ameliorated carbon tetrachloride-induced liver damage in rats, marked by decreased serum aminotransferase levels and lipid peroxidation intensity. Glutathione concentrations increased in a dose-dependent manner. Histological morphometric and immunohistochemical analysis confirmed antioxidative and hepatoprotective potential. These findings imply that cultivated C.comatus could be considered a nutraceutical, having beneficial nutrient and therapeutic properties.
journal_name
R Soc Open Scijournal_title
Royal Society open scienceauthors
Stilinović N,Čapo I,Vukmirović S,Rašković A,Tomas A,Popović M,Sabo Adoi
10.1098/rsos.200900subject
Has Abstractpub_date
2020-09-02 00:00:00pages
200900issue
9issn
2054-5703pii
rsos200900journal_volume
7pub_type
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