Abstract：
BACKGROUND:Many neurosurgeons advocate subpial technique as the best technique to remove supratentorial gliomas. However, few authors clearly defined advantages and features of this technique. The aim of our study is to describe microsurgical subpial technique related to glioma surgery, with regard to its safety and cost effectiveness. METHODS:We analysed retrospectively all consecutive patients surgically treated for supratentorial glioma from January 2017 to April 2018 at Neurosurgery Department of Neuromed Institute. All patients underwent to surgical glioma resection performing microsurgical subpial technique. Extent of resection and neurological complications were evaluated as primary outcomes; Karnofsky Performance Status and postoperative edema extent were secondary outcomes. Statistical analysis was obtained. RESULTS:The study included 70 patients. Gross Total Removal was obtained in 91,3% of patients with low grade glioma and in 81% of patients with high grade glioma. Neurological complications amounted to 34% at early assessment in low grade glioma patients, which were permanent at 3 months in 17% of patients. In high grade glioma patients, neurological complications amounted to 51% at early assessment, which were permanent at 3 months in 25% of them. CONCLUSIONS:We obtained good postoperative results with regard to the extent of tumor resection using this technique. Subpial resection is an effective surgical technique to get a safer and more complete tumor resection. It should be combined with other modern neurosurgical tools such as neuronavigation, ultrasound and cortical mapping to obtain the best tumor resection and functional neurological preservation.
journal_name
J Neurosurg Scijournal_title
Journal of neurosurgical sciencesauthors
Lavalle L,D'elia A,Ciavarro M,Esposito Vdoi
10.23736/S0390-5616.20.05046-8subject
Has Abstractpub_date
2020-09-28 00:00:00eissn
0390-5616issn
1827-1855pii
S0390-5616.20.05046-8pub_type
杂志文章abstract：:It has been recently observed that arachidonic acid (AA) metabolites may modulate many of the mechanisms involved in tumor growth and metastasis. In order to clarify the role played in human brain tumors, authors have determined AA metabolic profiles in 63 surgical specimen of human intracranial tumors (mostly neuroep...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章,评审
doi：
更新日期：1989-01-01 00:00:00
abstract：:Minimally invasive spine surgery is a rapidly developing field that has the potential to decrease surgical morbidity and improve recovery compared to traditional spinal approaches. Minimally invasive approaches have been developed for all regions of the spine, but have been best documented for degenerative conditions ...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章,评审
doi：
更新日期：2012-03-01 00:00:00
abstract：:A 22-year-old male with unilateral facial, cochlear and glossopharyngeal cranial nerve dysfunction and ataxia that was slowly progressive over one year is described. Although clinically it was considered he probably had an acoustic neuroma, surgery revealed a pontine glioblastoma exophytic into the cerebellopontine an...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:The traditional dilemma making surgery for diffuse low-grade gliomas (DLGGs) challenging is underlain by the need to optimize tumor resection in order to significantly increase survival versus the risk of permanent neurological morbidity. Development of neuroimaging led neurosurgeons to achieve tumorectomy according t...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章,评审
doi：
更新日期：2015-12-01 00:00:00
abstract：:The improved knowledge of clinical and emodynamical aspects of extracranial arteriovenous malformations in the 18 th century provided a foundation for the understanding and treatment of cerebrovascular pathology. It was not until the late 19 th century that detailed clinicopathological reports of intracranial arteriov...
journal_title：Journal of neurosurgical sciences
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:The epidemiological and clinical profile of Chronic Post-Traumatic Headache (CPTH) has been studied in 57 out of 130 consecutive patients hospitalized, following closed head injuries, at the Institute of Neurosurgery of the University of Milan. The incidence of CPTH has been 44%. Age of the patients ranged between 4 a...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1983-07-01 00:00:00
abstract：AIM:Mesenchymal stem cells (MSCs) migrate in response to chemokines and possess extensive tropism for experimental glioma. Antitumor effects have been reported following intracranial and intravenous administration of gene-modified MSCs. Among the different routes for cell transplant, the intraventricular (IV) approach ...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
abstract：:The Authors report their results on the treatment of 10 cases of primary spinal epidural lymphoma. All patients underwent surgery followed by radiotherapy and 60% of them improved after treatment. The Authors stress the importance the preoperative neurological status and early diagnosis play on the prognosis. They con...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1986-07-01 00:00:00
abstract：:Echinococcosis is a potentially fatal parasitic disease that can affect many animals and humans. The disease results from infection by tapeworm larvae of the genus Echinococcus--notably, E. granulosus, E. multilocularis, E. vogeli andE. oligarthrus. Cyst hydatid disease is usually seen in adults, and mainly affects li...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:A selected panel of monoclonal antibodies (MoAbs) directed to distinct tumor associated antigens (TAA) has been tested to define the capability of these reagents to differentiate among metastatic carcinoma, lymphoma and primary brain tumor on cytologic specimens obtained with stereotactic techniques. Results obtained ...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:The Authors report their case material concerning some basic items of the dysraphic pathology of the Posterior Fossa: 22 cases of Dandy Walker syndromes (DWS) and "Arachnoid Cysts" (PFC). The mean clinical findings (predominant involvement of the vestibular structures of the brain stem in the DWS, frequent epileptic s...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:The Authors report 4 cases of spinal lipomas: 2 intradural, 2 completely intrarachidian extradural. The intradural lipomas observed were 2 cases in the lumbo-sacral area, both operated on by the partial removal of the lesion with very good clinical results; histologically they were found to be 2 fibrolipomas. The 2 ca...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1974-04-01 00:00:00
abstract：:The authors' experience in the routine use of temporary clipping procedures in the surgery of endocranial aneurysms is reported. To analyse the validity of such a method we compared the outcome in a series of 153 aneurysms operated according to the traditional procedure (temporary clipping of the afferent vessel only ...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Nine patients out of more than 300 with severe Graves' ophthalmopathy followed in this institution were submitted to orbital decompression carried out on 16 eyes by a three-wall procedure consisting of a transfrontal approach with the removal of the roof, the lateral wall and part of the floor of the orbit. All patien...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:The authors present the results of a long-term follow up of 52 juvenile head-injured patients who showed early epileptic seizures. The purpose of this study is to stress the role of long-term prognosis in the early seizures and to determine in which cases a treatment preventing late seizures is eligible. They consider...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：BACKGROUND:A radical surgery of spine metastases is not possible in many cases, especially by elder multi morbid patients. The modern CAVITY/coblation method offers a very good therapeutic alternative for such patients. The goal of this paper was to evaluate and present the method as well as the results of the treatmen...
journal_title：Journal of neurosurgical sciences
pub_type： 临床试验,杂志文章
doi：10.23736/S0390-5616.16.03690-0
更新日期：2017-12-01 00:00:00
abstract：:Traumatic brain injury (TBI) is a common cause of permanent disability for which clinical management remains suboptimal. Elevated intracranial pressure (ICP) is a common sequela following TBI leading to death and permanent disability if not properly managed. While clinicians often employ stepwise acute care algorithms...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章,评审
doi：10.23736/S0390-5616.17.04133-9
更新日期：2019-08-01 00:00:00
abstract：:The authors evaluate the effectiveness of combination groups of antiedema pharmacological agents on experimental transient bilateral cerebral ischemia. The results show that dexamethasone and furosemide appear to be the most useful combination group. However, the improvement of post-ischemic vascular re-perfusion is n...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:Despite decades of therapeutic and molecular refinements, the prognosis of patients with glioblastoma (GBM) still remains unfavorable. Integrative clinical studies allow a better understanding of the natural evolution of GBM. To assess independent predictors of overall survival (OS) and progression free surv...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：10.23736/S0390-5616.20.04850-X
更新日期：2020-02-04 00:00:00
abstract：:In the routine practice of neurosurgery, the attainment of appropriate hemostasis during and after surgery is of the utmost importance. In the last few years, we have noticed that in several cases the standard coagulation methods (bipolar, Tabotamp, Spongostan) were not sufficient; in particular, patients with intrapa...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：10.23736/S0390-5616.16.03362-2
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Economical studies on surgery of intracranial aneurysms have considered only the significant benefit of surgical approach on unruptured aneurysms and no studies have been performed comparing cost/benefit analysis of early vs delayed surgery. The present study was retrospectively performed in order to verify ...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:Glioblastoma multiforme (GBM) is the most common malignant primary brain neoplasm, notorious for being able to evade and suppress the immune-system. We present a new immunotherapeutic approach that can potentially overcome or circumvent many of the GBM laden obstacles for an efficient antitumor immune response. In thi...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章,评审
doi：10.23736/S0390-5616.16.03755-3
更新日期：2017-08-01 00:00:00
abstract：AIM:The aim of this study was to study the effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats at different times, and to study the mechanism of neuroprotection with hyperbaric oxygen preconditioning after spinal cord injury. METHODS:Fifty-five adult Sprague-Dawle...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：: ...
journal_title：Journal of neurosurgical sciences
pub_type： 信件
doi：10.23736/S0390-5616.17.04156-X
更新日期：2019-04-01 00:00:00
abstract：:The authors propose a new experimental model of nervous anastomosis between intercostal and lumbar nerves in rabbit with the purpose of providing a technique to by-pass a spinal lesion. Before carrying out the surgical experiments, an histological study has been performed on the donor and receiver nerves which demonst...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1984-07-01 00:00:00
abstract：BACKGROUND:This study aimed to compare the accuracy of screw placement between open pedicle screw fixation and percutaneous pedicle screw fixation (MIS) for the treatment of thoracolumbar spine fractures (TSF). METHODS:forty-nine patients with acute TSF who were treated with transpedicular screw fixation from January ...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：10.23736/S0390-5616.18.04439-9
更新日期：2021-02-01 00:00:00
abstract：AIM:Tethered cord syndrome (TCS) is a stretch-induced functional disorder of the spinal cord, which is directly related to filum fixation. Classic surgical approaches to the filum involve open surgery and include varying amounts of spinal bone removal. In an effort to reduce the morbidity and mortality of these procedu...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:A 49-year-old male, with a relatively uncommon multiple neurilemmoma, exhibited symptoms of cauda equina compression. Following a diagnosis of multiple tumor of the cauda equina and extradural cyst, based on myelography and CTM, the tumors at L1-L2, the left S1 nerve root, and left hip were resected. Three years after...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：AIM:The authors report the results of anterior submuscular transposition, on a clinical series of selected patients with severe cubital tunnel syndrome. In these patients, the degree of ulnar nerve compression was valued using a grading system that includes measurements of motor and sensitive function. In this series, ...
journal_title：Journal of neurosurgical sciences
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:Multiple meningiomas in different neuraxial compartments are quite rare. The authors report two new cases of association between cranial and spinal meningiomas, one of them in a patient operated upon for multiple intracranial meningiomas. The first case was a 60-year-old woman with progressive paraparesis who had been...
journal_title：Journal of neurosurgical sciences
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
