Abstract:
AIM:The aim of this study was to study the effect of preconditioning with hyperbaric oxygen on neural cell apoptosis after spinal cord injury in rats at different times, and to study the mechanism of neuroprotection with hyperbaric oxygen preconditioning after spinal cord injury. METHODS:Fifty-five adult Sprague-Dawley rats were randomly divided into 3 groups, a hyperbaric oxygen preconditioning group (Hoping, N.=25), a normal injury group (NI, N.=25) and a control group (CON, N.=5). The acute spinal cord injury rat models were established using Allen's method, the spinal cord injury selections were obtained separately after injury day 1, 5, 7, 10 and 14, the neural cell apoptosis after the spinal cord injury in the rat was detected by the HE staining and TUNEL method. RESULTS:The TUNEL-positive apoptotic cells were found in both the hyperbaric oxygen preconditional group and in the normal injury group. However, There was a statistically significant difference between each group (P<0.05). In the hyperbaric oxygen preconditioning group, the number of apoptotic cells decreased, while the neurofunction of the spinal cord was improved compared with the other two groups. CONCLUSION:HBO preconditioning can reduce the number of apoptotic cells and promote the nerve functional recovery in rats after spinal cord injury, which provide some experimental basis for currently clinical hyperbaric oxygen therapy.
journal_name
J Neurosurg Scijournal_title
Journal of neurosurgical sciencesauthors
Lu PG,Feng H,Yuan SJ,Zhang RW,Li M,Hu R,Liu ZS,Yin Jsubject
Has Abstractpub_date
2013-09-01 00:00:00pages
253-8issue
3eissn
0390-5616issn
1827-1855pii
R38Y2013N03A0253journal_volume
57pub_type
杂志文章abstract::A rare case of complex cerebral arteriovenous fistula in an infant is reported. An 8-month-old boy first presented with a syndrome of increased intracranial pressure. Neuroradiological assessment showed a direct intracerebral arteriovenous shunt with marked venous engorgement. No hemorrhage was evident. Direct surgica...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::The results of a retrospective study of 24 adult patients with occult dysraphism are described. There were 15 males and 9 females, with an average age of 31.1 years. Specific circumstances precipitated symptomatic onset in 67% of patients. Pain, often referred to the anorectal region, was the most common presenting sy...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Adjacent-level disease after anterior cervical discectomy and fusion (ACDF) occurs in a significant proportion of patients and frequently requires revision operation. Methods using traditional plates typically require removal of the plate with anecdotally increased operative-time and morbidity. We review our...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:10.23736/S0390-5616.18.04172-3
更新日期:2020-10-01 00:00:00
abstract::During the last seven years (1985-91) 28 primary tumours in the cauda among 104 intraspinal tumors were observed. The largest group (71%) comprised ependymomas and neurinomas. The rest included 5 lipomas, 2 astrocytomas and 1 epidermoid. Low-back pain without or with sciatic or crural irradiation was the most common i...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::The action of some extracts of human glioblastoma of the haemolytic complement of human and xenogeneic sera has been examined. The study suggests that the antigenic products of some human glioblastomas may induce an inhibiting effect on the haemolytic complement of human, as well as xenogeneic (rat and rabbit), sera. ...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract:AIM:Deep brain stimulation (DBS) is the treatment of choice for advanced Parkinson's disease. The target co-ordinates are traditionally calculated in relation to the intercommissural distance. Anterior (AC) and posterior commissures (PC) may be visualised by the means of ventriculography, CT or MRI. METHODS:We have st...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::The Authors report a case of intracranial meningioma in two sisters, with no evidence of neurofibromatosis. A study of the karyotype has been performed; in one patient we have found a pericentric inversion of one chromosome 9. The possible role of the genetical factors in the develop of familial meningiomas is discuss...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章,评审
doi:
更新日期:1987-07-01 00:00:00
abstract:AIM:Tethered cord syndrome (TCS) is a stretch-induced functional disorder of the spinal cord, which is directly related to filum fixation. Classic surgical approaches to the filum involve open surgery and include varying amounts of spinal bone removal. In an effort to reduce the morbidity and mortality of these procedu...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Results from surgical series of tuberculum and planum sphenoidale meningiomas tends to be heterogeneous. Sekhar-Mortazavi tumor classification system has been recently proposed in order to predict the surgical risk and outcome. METHOD:We retrospectively reviewed a consecutive series of tuberculum and planum...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:10.23736/S0390-5616.18.04167-X
更新日期:2018-01-04 00:00:00
abstract:AIM:The authors report the results of anterior submuscular transposition, on a clinical series of selected patients with severe cubital tunnel syndrome. In these patients, the degree of ulnar nerve compression was valued using a grading system that includes measurements of motor and sensitive function. In this series, ...
journal_title:Journal of neurosurgical sciences
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::The authors describe a rare case of a primary central nervous system lymphoma of the cerebellopontine angle, extending into the right cavernous sinus and orbit. The patient presented with multiple right sided cranial nerve palsies and rapidly progressive proptosis and ophthalmoplegia of the right eye. Imaging revealed...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Recent clinical trials demonstrated the efficacy of thrombectomy for ischemic stroke against acute large vessel occlusion (LVO). To overcome the problem with excessive examination time for diagnosis of cerebral perfusion and/or the use of contrast agent to determine penumbra, we adopted a new magnetic resona...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:10.23736/S0390-5616.18.04607-6
更新日期:2018-11-21 00:00:00
abstract::Multidisciplinary efforts are being made to provide surgical teams with sensitive and specific tasks for language mapping in awake surgery. Researchers and clinicians have elaborated different tasks over time. A fair amount of work has been directed to study the neurofunctional correlates of some of these tasks, and t...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章,评审
doi:
更新日期:2015-12-01 00:00:00
abstract::The authors present a case of spinal epidural hematoma during anticoagulant therapy. Clinical presentation is characterized by classic paravertebral back pain, followed by progressive neurological deficit due to spinal cord and radicular compression, with sensory deficits and bladder disturbance. From the literature, ...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章,评审
doi:
更新日期:1995-03-01 00:00:00
abstract:AIM:The challenge in large cranial base meningiomas is total resection of the tumor with the least possible mortality and morbidity. During the last two decades the technical approaches for anterior skull base tumors have shown a considerable progress, providing a wide exposure with minimal brain retraction. The purpos...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract::The occurrence of a so called azygous anomaly of the distal ACA, consisting in a single branch, is rare. Authors report two cases of azygous aneurysm on which surgery was performed successfully, and describe their angiographic characteristics, the frequent association of an aneurysm with azygous and the morphological ...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::(1) In a total of 100 patients with traumatic coma who were admitted to the intensive care unit of our Department of Neurosurgery we examined the effect of Encephabol after intravenous administration. (2) Compared to patients with the same clinico-neurological conditions who were, however, not treated with Encephabol,...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The authors propose the use of CT scan in the diagnosis of patients with suspected craniostenosis. The technique offers a valid preoperative screening, uncovering associated malformations, and in addition, is particularly useful in following assessment. It can therefore, reduce surgical indications and limit conventio...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::A small group of patients with carpal tunnel syndrome (CTS) can present recurrences and persistent symptoms of CTS after its surgical release. If recurrence is due to scarring between median nerve and surrounding tissue (true recurrence of CTS, transverse carpal ligament [TCL] reconstruction with transposition flap te...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:2003-06-01 00:00:00
abstract::A case of a 52-year-old male presented with an unusual penetrating brain injury with nasal entry. At admission he had erythema of periorbital soft tissue in the left eye and epistaxis. His neurological condition was lethargic (Glasgow Coma Scale of 13) with nonfluent aphasia. Computed tomography scan revealed intracra...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::The authors describe 2 patients with solitary cerebral metastasis occurring 13 years after treatment for a renal tumor in one and 17 in the other. Both patients are alive 30 and 36 months after surgery respectively. The pathogenetic and therapeutic features typical of this type of solitary metastasis with late-onset a...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::The authors report the case of an encapsulated intradiploic hematoma observed in a 2 year old patient who, 6 months prior to their observation, underwent an internal CSF drainage for hydrocephalus. The surgical findings are described and the possible etiopathological causes discussed. ...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1980-04-01 00:00:00
abstract:BACKGROUND:The short pars and the narrowed surgical corridor for far lateral L5S1 herniation make the transpars approach challenging. The aim of this study is to determine the feasibility, efficacy and safety of the transpars microscopic approach for the treatment of L5-S1 foraminal and extraforaminal lumbar disc herni...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:10.23736/S0390-5616.20.05165-6
更新日期:2020-12-09 00:00:00
abstract::A preliminary report on the immunological monitoring of primary intracranial neoplasms is presented. The most important findings concerning B-cells and T-cells mediated immunity and delayed hypersensitivity reactions in this kind of patients, are discussed. Among the fairly significant immunobiological pictures, the A...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::A case of hypertensive endoventricular pneumocephalus associated with rhinoliquorrea raised after about 2 years from the application of ventriculo-peritoneal shunt for hydrocephalus by stenosis of aqueduct is presented. The causes of such complication and diagnostic possibilities to point out the fistula by CT and ven...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::Evolution of psychological disorders following head injury including memory disorders and other cognitive ones are common. The best known are psychiatric disturbances of various kind after lesions of frontal lobes. Cognitive, behavioural and emotional disorders are not usually seen in patients with bilateral temporal ...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:This study aimed to compare the accuracy of screw placement between open pedicle screw fixation and percutaneous pedicle screw fixation (MIS) for the treatment of thoracolumbar spine fractures (TSF). METHODS:forty-nine patients with acute TSF who were treated with transpedicular screw fixation from January ...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:10.23736/S0390-5616.18.04439-9
更新日期:2021-02-01 00:00:00
abstract::Arteriovenous malformations (AVM) can occur in the entire central nervous system with a predilection of the supratentorial intracranial compartment. Intracerebral hemorrhage is the most common clinical presentation of AVM and associated with a high morbidity and mortality rate. Correct management of these lesions is t...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章,评审
doi:
更新日期:2011-03-01 00:00:00
abstract::Lumbar stenosis patients typically present with neurogenic claudication or radiculopathy. Studies have shown the benefit of surgical management of lumbar stenosis for patients who fail medical management. Surgical management traditionally involved an open laminectomy and foramenotomies. The emergence of minimally inva...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章,评审
doi:
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:To investigate the microarray data on the gene expression profiles of intervertebral disc degeneration related to cytokine exposure. The purpose of the study was to identify the key genes that were differentially expressed in these disc cells compared to cells without inflammatory cytokine treatment, using b...
journal_title:Journal of neurosurgical sciences
pub_type: 杂志文章
doi:10.23736/S0390-5616.16.03326-9
更新日期:2018-02-01 00:00:00