Abstract：
BACKGROUND:The objective of this study was to examine changes in the prevalence of cytotoxic-associated gene A (CagA) positive Helicobacter pylori infection in Jinju, Korea, over the last 20 years. METHODS:Three cross-sectional analyses were conducted concurrently. A total of 1,305 serum samples were collected from 1994-1995, 2004-2005, and 2014-2015, respectively. The presence of immunoglobulin (Ig) G, IgA, and IgM antibodies against H. pylori CagA protein was examined by western blotting. RESULTS:Overall, seropositivity for anti-CagA IgG antibody was significantly decreased from 63.2% to 42.5% over the last 20 years (P < 0.001). Anti-CagA IgG seropositivities in children and young adults aged 10-29 years decreased from 1994 (60.0%-85.0%) to 2015 (12.5%-28.9%). The age when plateau of increasing IgG seropositivity was reached in each study period shifted from the 15-19 year-old group in 1994-1995 (85.0%) to the 40-49 year-old group in 2014-2015 (82.5%). Overall seropositive rates of anti-CagA IgA and IgM antibodies did not change significantly either over the last 20 years. CONCLUSION:H. pylori infection rate in children and young adults declined over 20 years in Jinju, probably due to improved sanitation, housing, or economy.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Park JS,Jun JS,Ryu EY,Yeom JS,Park ES,Seo JH,Lim JY,Park CH,Woo HO,Baik SC,Lee WK,Cho MJ,Rhee KH,Youn HSdoi
10.3346/jkms.2020.35.e259subject
Has Abstractpub_date
2020-08-17 00:00:00pages
e259issue
32eissn
1011-8934issn
1598-6357pii
35.e259journal_volume
35pub_type
杂志文章abstract：:The aim of this study was to determine whether maternal serum C-reactive protein (CRP) is of value in predicting funisitis and early-onset neonatal sepsis (EONS) in women with preterm labor or preterm premature rupture of membranes (PROM). This retrospective cohort study included 306 consecutive women with preterm lab...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2012.27.6.674
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abstract：:In patients with chronic hepatitis C virus disease, there is a high incidence of development of hepatocellular carcinoma (HCC) in the process of transition from chronic hepatitis to hepatic cirrhosis. Although ginseng traditionally has been used mainly as a nutritional supplement in Asian countries, a case-control stu...
journal_title：Journal of Korean medical science
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
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abstract：:This study was performed to determine the incidence and serogroups of meningococcal disease in the Korean Army. From August 2000 to July 2001, we identified prospective cases in the Korean Army. Meningococcal disease was confirmed by isolation of Neisseria meningitidis or detection of its antigen by latex agglutinatio...
journal_title：Journal of Korean medical science
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pub_type： 杂志文章
doi：10.3346/jkms.2005.20.3.402
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journal_title：Journal of Korean medical science
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.2012.27.S.S41
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journal_title：Journal of Korean medical science
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doi：10.3346/jkms.1999.14.5.539
更新日期：1999-10-01 00:00:00
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.1996.11.4.369
更新日期：1996-08-01 00:00:00
abstract：BACKGROUND:We aimed to validate Baveno VI and expanded Baveno VI criteria using two dimensional shear-wave elastography (2D-SWE) in compensated advanced chronic liver disease (cACLD) patients with alcohol as the main etiology. METHODS:Clinical data from 305 patients with cACLD who underwent a liver stiffness measureme...
journal_title：Journal of Korean medical science
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doi：10.3346/jkms.2020.35.e249
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journal_title：Journal of Korean medical science
pub_type： 杂志文章
doi：10.3346/jkms.1998.13.4.431
更新日期：1998-08-01 00:00:00
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journal_title：Journal of Korean medical science
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doi：10.3346/jkms.1996.11.1.44
更新日期：1996-02-01 00:00:00
abstract：:Donor shortage is a major limitation in organ transplantation. Several studies have reported that extracorporeal membrane oxygenation (ECMO)-assisted organ donation can be successfully completed without inducing warm ischemia in patients with brain death. The present report described clinical experience of three patie...
journal_title：Journal of Korean medical science
pub_type： 杂志文章
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pub_type： 杂志文章,多中心研究
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journal_title：Journal of Korean medical science
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更新日期：2017-06-01 00:00:00
abstract：:The purpose of this study was to assess the incidence and mortality of distal radius fracture among patients 50 years of age and older with diagnosis code (ICD10; S52.5, S52.6) and treatment code using a nationwide claims database from 2008 to 2012. All patients were followed using patient identification code to ident...
journal_title：Journal of Korean medical science
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abstract：:Alzheimer's disease (AD) is the most common form of dementia caused by neurodegenerative process and is tightly related to amyloid β (Aβ) and neurofibrillary tangles. The lack of early diagnostic biomarker and therapeutic remedy hinders the prevention of increasing population of AD patients every year. In spite of acc...
journal_title：Journal of Korean medical science
pub_type： 杂志文章,评审
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abstract：:Recently reports on toxocariasis are increasing by serodiagnosis in Korea. A previously healthy 17-yr-old boy complained of headache, fever, dyspnea, and anorexia. He showed symptoms and signs of eosinophilic meningitis with involvement of the lungs and liver. Specific IgG antibody to Toxocara canis larval antigen was...
journal_title：Journal of Korean medical science
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abstract：:This study was done to characterize the natural course of C-peptide levels in patients with type 1 diabetes and identify distinguishing characters among patients with lower rates of C-peptide decline. A sample of 95 children with type 1 diabetes was analyzed to retrospectively track serum levels of C-peptide, HbA1c, w...
journal_title：Journal of Korean medical science
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abstract：:The incidence of lower gastrointestinal bleeding (LGIB) is increasing; however, predictors of outcomes for patients with LGIB are not as well defined as those for patients with upper gastrointestinal bleeding (UGIB). The aim of this study was to identify the clinical outcomes and the predictors of poor outcomes for pa...
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