Abstract:
:In patients with chronic hepatitis C virus disease, there is a high incidence of development of hepatocellular carcinoma (HCC) in the process of transition from chronic hepatitis to hepatic cirrhosis. Although ginseng traditionally has been used mainly as a nutritional supplement in Asian countries, a case-control study found that it may inhibit the development of HCC. We therefore planned a clinical study of HCC prevention by medicinal ginseng. The subjects are patients with chronic C virus disease (chronic hepatitis and hepatic cirrhosis), who are high risk group for HCC. This intervention study is a multi-center, double-blind, randomized controlled trial. The participants will be randomly divided into two groups. The test sample (1 g of red ginseng powder per day) will be administered for 5 yr, and ginseng intake will be prohibited during the administration period. The primary endpoint of this study is the development of HCC. Target number of recruiting subjects are 300. The participants should be registered from February 2001 to January 2003.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Ginseng-HCC Chemopreventive Study Osaka Group.doi
10.3346/jkms.2001.16.S.S70keywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
S70-4eissn
1011-8934issn
1598-6357pii
200112s070journal_volume
16 Supplpub_type
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