Using proximity extension proteomics assay to discover novel biomarkers associated with circulating leptin levels in patients with type 2 diabetes.

abstract：:Group-IVa elements silicon and germanium are known for their semiconducting properties at room temperature, which are technologically critical. Metallicity and superconductivity are found at higher pressures only, Ge β-tin (tI4) being the first high-pressure metallic phase in the phase diagram. However, recent experim...

journal_title：Scientific reports

authors： Selli D,Baburin IA,Martoňák R,Leoni S

更新日期：2013-01-01 00:00:00

abstract：:Immunoproteasomes are known for their involvement in antigen presentation. However, their broad tissue presence and other evidence are indicative of nonimmune functions. We examined a role for immunoproteasomes in cellular responses to the endogenous and environmental carcinogen formaldehyde (FA) that binds to cytosol...

journal_title：Scientific reports

authors： Ortega-Atienza S,Krawic C,Watts L,McCarthy C,Luczak MW,Zhitkovich A

更新日期：2017-04-05 00:00:00

abstract：:Two yellow luminescence bands related to different defects have been revealed in undoped GaN grown by hydride vapor phase epitaxy (HVPE). One of them, labeled YL1, has the zero-phonon line (ZPL) at 2.57 eV and the band maximum at 2.20 eV at low temperature. This luminescence band is the ubiquitous yellow band observed...

journal_title：Scientific reports

authors： Reshchikov MA,McNamara JD,Helava H,Usikov A,Makarov Y

更新日期：2018-05-25 00:00:00

abstract：:We present a new class of TiBw/Ti6Al4V composites with a network reinforcement architecture that exhibits a significant creep resistance compared to monolithic Ti6Al4V alloys. Creep tests performed at temperatures between 773 K and 923 K and stress range of 100 MPa-300 MPa indicate both a significant improvement of th...

journal_title：Scientific reports

authors： Wang S,Huang LJ,Geng L,Scarpa F,Jiao Y,Peng HX

更新日期：2017-01-17 00:00:00

abstract：:Still recently, bacterial fluid suspensions have motivated a lot of works, both experimental and theoretical, with the objective to understand their collective dynamics from universal and simple rules. Since some species are active, most of these works concern the strong interactions that these bacteria exert on a for...

journal_title：Scientific reports

authors： Ben Amar M

更新日期：2016-02-18 00:00:00

abstract：:Chemical separation has great importance in industrial applications. Separation of xylene isomers still prevails to be one of the most important challenges in chemical industry, due to the large amount of commercial use of p-xylene in the production of beverage bottles, fibers and films. A novel Zn(II)-based dynamic c...

journal_title：Scientific reports

authors： Mukherjee S,Joarder B,Manna B,Desai AV,Chaudhari AK,Ghosh SK

更新日期：2014-07-21 00:00:00

abstract：:microRNAs are an abundant class of small non-coding RNAs that control gene expression post-transcriptionally. Importantly, microRNA activity participates in the regulation of cellular processes and is a potentially valuable source of biomarkers in the diagnosis and prognosis of human diseases. Here we introduce miQPCR...

journal_title：Scientific reports

authors： Benes V,Collier P,Kordes C,Stolte J,Rausch T,Muckentaler MU,Häussinger D,Castoldi M

更新日期：2015-06-25 00:00:00

abstract：:The repeated measurements of heart rate variability (HRV) is more relevant than a single HRV measurement in predicting patient prognosis but is less addressed previously. This prospective study aimed to investigate the association between repeated measurements of HRV and long-term mortality in chronic hemodialysis pat...

journal_title：Scientific reports

authors： Chang YM,Huang YT,Chen IL,Yang CL,Leu SC,Su HL,Kao JL,Tsai SC,Jhen RN,Shiao CC

更新日期：2020-01-21 00:00:00

abstract：:All solid-state lithium-ion transistors are considered as promising synaptic devices for building artificial neural networks for neuromorphic computing. However, the slow ionic conduction in existing electrolytes hinders the performance of lithium-ion-based synaptic transistors. In this study, we systematically explor...

journal_title：Scientific reports

authors： Nikam RD,Kwak M,Lee J,Rajput KG,Banerjee W,Hwang H

更新日期：2019-12-11 00:00:00

abstract：:We have successfully grown centimeter-sized layered [Formula: see text] single crystals under high oxygen pressures of 120-150 bar by the floating zone technique. This enabled us to perform neutron scattering experiments where we observe close to quarter-integer magnetic peaks below [Formula: see text] that are accomp...

journal_title：Scientific reports

authors： Guo H,Li ZW,Chang CF,Hu Z,Kuo CY,Perring TG,Schmidt W,Piovano A,Schmalzl K,Walker HC,Lin HJ,Chen CT,Blanco-Canosa S,Schlappa J,Schüßler-Langeheine C,Hansmann P,Khomskii DI,Tjeng LH,Komarek AC

更新日期：2020-10-22 00:00:00

abstract：:The effects of sea salt aerosols (SSA) on cloud microphysical processes, precipitation, and upper troposphere/lower stratosphere water vapour in tropical cyclones were studied with the Weather Research and Forecasting with Chemistry model. Two numerical experiments were conducted: a control experiment (CTL) and an exp...

journal_title：Scientific reports

authors： Jiang B,Wang D,Shen X,Chen J,Lin W

更新日期：2019-10-22 00:00:00

abstract：:Hybrid cells of Nicotiana suaveolens x N. tabacum grow normally at 36 °C, but immediately express lethality due to probable autoimmune response when transferred from 36 to 28 °C. Our recent study showed that the temperature-sensitive lethality of these hybrid cells occurs through autolytic programmed cell death (PCD)....

journal_title：Scientific reports

authors： Ueno N,Kashiwagi M,Kanekatsu M,Marubashi W,Yamada T

更新日期：2019-07-15 00:00:00

abstract：:We consider an optimal quantum key distribution setup based on minimal number of measurement bases with binary yields used by parties against an eavesdropper limited only by the no-signaling principle. We note that in general, the maximal key rate can be achieved by determining the optimal tradeoff between measurement...

journal_title：Scientific reports

authors： Kamaruddin S,Shaari JS

更新日期：2016-08-03 00:00:00

abstract：:The importance of evaluating physical cues in cancer research is gradually being realized. Assessment of cancer cell physical appearance, or phenotype, may provide information on changes in cellular behavior, including migratory or communicative changes. These characteristics are intrinsically different between malign...

journal_title：Scientific reports

authors： Ware MJ,Tinger S,Colbert KL,Corr SJ,Rees P,Koshkina N,Curley S,Summers HD,Godin B

更新日期：2015-07-13 00:00:00

abstract：:The high density nucleation of α-Al2O3 nanocrystallites was observed by rapid heating of the aluminum formate hydroxide-based precursor powder at 1200 °C for 50 s. The nucleation of α-Al2O3 nanocrystallites with less 10 nm in size from high purity aluminum oxide matrix has not been observed to our knowledge. Based on ...

journal_title：Scientific reports

authors： Yoshida M,Kato Y,Oumi Y,Sakurada O,Tanaka M,Wada M,Kitaoka S

更新日期：2019-10-17 00:00:00

abstract：:Exposure to affective stimuli could enhance perception and facilitate attention via increasing alertness, vigilance, and by decreasing attentional thresholds. However, evidence on the impact of affective sounds on perception and attention is scant. Here, a novel aspect of affective facilitation of attention is studied...

journal_title：Scientific reports

authors： Asutay E,Västfjäll D

更新日期：2017-09-04 00:00:00

abstract：:Pseudomonas aeruginosa is an opportunistic pathogen and a leading cause of nosocomial infections. Unfortunately, P. aeruginosa has low antibiotic susceptibility due to several chromosomally encoded antibiotic resistance genes. Hence, we carried out mechanistic studies to determine how azithromycin affects quorum sensi...

journal_title：Scientific reports

authors： Zeng J,Zhang N,Huang B,Cai R,Wu B,E S,Fang C,Chen C

更新日期：2016-04-14 00:00:00

abstract：:Transient receptor potential melastatin 8 (TRPM8), a nonselective cation channel, is the predominant mammalian cold temperature thermosensor and it is activated by cold temperatures and cooling compounds, such as menthol and icilin. Because of its role in cold allodynia, cold hyperalgesia and painful syndromes TRPM8 a...

journal_title：Scientific reports

authors： Beccari AR,Gemei M,Lo Monte M,Menegatti N,Fanton M,Pedretti A,Bovolenta S,Nucci C,Molteni A,Rossignoli A,Brandolini L,Taddei A,Za L,Liberati C,Vistoli G

更新日期：2017-09-08 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease and a major health problem in the elderly population. No disease-modifying osteoarthritis drug (DMOAD) has been made available for clinical use. Here we present a disease-modifying strategy for OA, focusing on messenger RNA (mRNA) delivery of a therapeutic tr...

journal_title：Scientific reports

authors： Aini H,Itaka K,Fujisawa A,Uchida H,Uchida S,Fukushima S,Kataoka K,Saito T,Chung UI,Ohba S

更新日期：2016-01-05 00:00:00

abstract：:Recently, sex steroid membrane receptors garnered world-wide attention because they may be related to sex hormone-mediated unknown rapid non-genomic action that cannot be currently explained by their genomic action via nuclear receptors. Progesterone affects cell proliferation and survival via non-genomic effects. In ...

journal_title：Scientific reports

authors： Kasubuchi M,Watanabe K,Hirano K,Inoue D,Li X,Terasawa K,Konishi M,Itoh N,Kimura I

更新日期：2017-07-12 00:00:00

abstract：:The gut microbiota (GM) is related to obesity and other metabolic diseases. To detect GM markers for obesity in patients with different metabolic abnormalities and investigate their relationships with clinical indicators, 1,914 Chinese adults were enrolled for 16S rRNA gene sequencing in this retrospective study. Base...

journal_title：Scientific reports

authors： Zeng Q,Li D,He Y,Li Y,Yang Z,Zhao X,Liu Y,Wang Y,Sun J,Feng X,Wang F,Chen J,Zheng Y,Yang Y,Sun X,Xu X,Wang D,Kenney T,Jiang Y,Gu H,Li Y,Zhou K,Li S,Dai W

更新日期：2019-09-17 00:00:00

abstract：:In crystalline metals at small scales, the dislocation density will be increased by stochastic events of dislocation network, leading to a universal power law for various material structures. In this work, we develop a model obeyed by a probability distribution of dislocation density to describe the dislocation format...

journal_title：Scientific reports

authors： Huang GR,Huang JC,Tsai WY

更新日期：2016-12-15 00:00:00

abstract：:Exfoliated monolayer graphene flakes were embedded in a polymer matrix and loaded under axial compression. By monitoring the shifts of the 2D Raman phonons of rectangular flakes of various sizes under load, the critical strain to failure was determined. Prior to loading care was taken for the examined area of the flak...

journal_title：Scientific reports

authors： Androulidakis C,Koukaras EN,Frank O,Tsoukleri G,Sfyris D,Parthenios J,Pugno N,Papagelis K,Novoselov KS,Galiotis C

更新日期：2014-06-12 00:00:00

abstract：:Myocardial infarction (MI) can result in sympathetic nerve loss in the infarct region. However, the contribution of hypo-innervation to electrophysiological remodeling, independent from MI-induced ischemia and fibrosis, has not been comprehensively investigated. We present a novel mouse model of regional cardiac sympa...

journal_title：Scientific reports

authors： Tapa S,Wang L,Francis Stuart SD,Wang Z,Jiang Y,Habecker BA,Ripplinger CM

更新日期：2020-11-02 00:00:00

abstract：:The objective of this study was to determine the prevalence of sexual dysfunction in Saudi and non-Saudi female health care providers in Jeddah, Saudi Arabia. One -hundred twenty (60 Saudi and 60 non-Saudi) sexually active female health care professionals in Jeddah, Saudi Arabia, were anonymously surveyed using the En...

journal_title：Scientific reports

authors： Rouzi AA,Sahly N,Sawan D,Kafy S,Alzaban F

更新日期：2015-01-20 00:00:00

abstract：:Parasite death via ion channel activations is the hallmark of anthelmintic and antiparasitic drugs. Glutamate gated chloride channel (GluCl) is a prominent targets for drug selection and design in parasitology. We report several iodine-fluorine based lead activators of GluCl by computational studies and structure-acti...

journal_title：Scientific reports

authors： Rajasekharan SK,Lee JH,Ravichandran V,Kim JC,Park JG,Lee J

更新日期：2019-02-14 00:00:00

abstract：:SLC7A10 (Asc-1) is a sodium-independent amino acid transporter known to facilitate transport of a number of amino acids including glycine, L-serine, L-alanine, and L-cysteine, as well as their D-enantiomers. It has been described as a neuronal transporter with a primary role related to modulation of excitatory glutama...

journal_title：Scientific reports

authors： Ehmsen JT,Liu Y,Wang Y,Paladugu N,Johnson AE,Rothstein JD,du Lac S,Mattson MP,Höke A

更新日期：2016-10-19 00:00:00

abstract：:Revisiting threat-related scenes elicits fear and activates a brain network related to cognitive-affective processing. Prior experience may contribute to the present fearful experience. We aimed to investigate (a) patterns of brain activation associated with individual differences in past fearful experiences (pFear) a...

journal_title：Scientific reports

authors： Lin CS,Wu CY,Wu SY,Lin HH

更新日期：2018-03-23 00:00:00

abstract：:Liver cirrhosis is a severe disease with major impact on the overall health of the patient including poor oral health. Lately, there has been increasing focus on oral diseases as cirrhosis-related complications due to the potential impact on systemic health and ultimately mortality. Periodontitis is one of the most co...

journal_title：Scientific reports

authors： Jensen A,Ladegaard Grønkjær L,Holmstrup P,Vilstrup H,Kilian M

更新日期：2018-07-16 00:00:00

abstract：:MicroRNAs (miRNAs) are important post-transcriptional regulators involved in animal adipogenesis, however, their roles in bovine fat deposition remain poorly understood. In the present study, we conducted a comparative RNA sequencing to identify the key miRNAs involved in beef lipid accumulation by comparing the backf...

journal_title：Scientific reports

authors： Guo Y,Zhang X,Huang W,Miao X

更新日期：2017-03-08 00:00:00