当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Ethical issues in global neuroimaging genetics collaborations.

Ethical issues in global neuroimaging genetics collaborations.

Abstract：

:Neuroimaging genetics is a rapidly developing field that combines neuropsychiatric genetics studies with imaging modalities to investigate how genetic variation influences brain structure and function. As both genetic and imaging technologies improve further, their combined power may hold translational potential in terms of improving psychiatric nosology, diagnosis, and treatment. While neuroimaging genetics studies offer a number of scientific advantages, they also face challenges. In response to some of these challenges, global neuroimaging genetics collaborations have been created to pool and compare brain data and replicate study findings. Attention has been paid to ethical issues in genetics, neuroimaging, and multi-site collaborative research, respectively, but there have been few substantive discussions of the ethical issues generated by the confluence of these areas in global neuroimaging genetics collaborations. Our discussion focuses on two areas: benefits and risks of global neuroimaging genetics collaborations and the potential impact of neuroimaging genetics research findings in low- and middle-income countries. Global neuroimaging genetics collaborations have the potential to enhance relations between countries and address global mental health challenges, however there are risks regarding inequity, exploitation and data sharing. Moreover, neuroimaging genetics research in low- and middle-income countries must address the issue of feedback of findings and the risk of essentializing and stigmatizing interpretations of mental disorders. We conclude by examining how the notion of solidarity, informed by an African Ethics framework, may justify some of the suggestions made in our discussion.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Palk A,Illes J,Thompson PM,Stein DJ

doi

10.1016/j.neuroimage.2020.117208

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

117208

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(20)30694-7

journal_volume

221

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging.

    abstract：PURPOSE:To examine the extent of genetic damage, assessed from deoxyribonucleic acid (DNA) double-strand breaks (DSBs) and micronuclei (MN) in peripheral blood mononuclear cells obtained from individuals repeatedly exposed to 7T Magnetic Resonance Imaging (MRI). MATERIALS AND METHODS:The study protocol was approved by...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.03.023

    authors： Fatahi M,Reddig A,Vijayalaxmi,Friebe B,Hartig R,Prihoda TJ,Ricke J,Roggenbuck D,Reinhold D,Speck O

    更新日期：2016-06-01 00:00:00

  • BOLD and blood volume-weighted fMRI of rat lumbar spinal cord during non-noxious and noxious electrical hindpaw stimulation.

    abstract：:Spinal cord fMRI is a useful tool for studying spinal mechanisms of pain, hence for analgesic drug development. Its technical feasibility in both humans and rats has been demonstrated. This study investigates the reproducibility, robustness, and spatial accuracy of fMRI of lumbar spinal cord activation due to transcut...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.11.010

    authors： Zhao F,Williams M,Meng X,Welsh DC,Coimbra A,Crown ED,Cook JJ,Urban MO,Hargreaves R,Williams DS

    更新日期：2008-03-01 00:00:00

  • The development of corpus callosum microstructure and associations with bimanual task performance in healthy adolescents.

    abstract：:Cross-sectional and longitudinal volumetric studies suggest that the corpus callosum (CC) continues to mature structurally from infancy to adulthood. Diffusion tensor imaging (DTI) provides in vivo information about the directional organization of white matter microstructure and shows potential for elucidating even mo...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.10.018

    authors： Muetzel RL,Collins PF,Mueller BA,M Schissel A,Lim KO,Luciana M

    更新日期：2008-02-15 00:00:00

  • A vascular anatomical network model of the spatio-temporal response to brain activation.

    abstract：:Neuronal activity-induced changes in vascular tone and oxygen consumption result in a dynamic evolution of blood flow, volume, and oxygenation. Functional neuroimaging techniques, such as functional magnetic resonance imaging, optical imaging, and PET, provide indirect measures of the neural-induced vascular dynamics ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.12.061

    authors： Boas DA,Jones SR,Devor A,Huppert TJ,Dale AM

    更新日期：2008-04-15 00:00:00

  • DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity.

    abstract：:Diffusion tensor imaging (DTI) studies in schizophrenia demonstrate lower anisotropic diffusion within white matter due either to loss of coherence of white matter fiber tracts, to changes in the number and/or density of interconnecting fiber tracts, or to changes in myelination, although methodology as well as locali...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2005.03.026

    authors： Kubicki M,Park H,Westin CF,Nestor PG,Mulkern RV,Maier SE,Niznikiewicz M,Connor EE,Levitt JJ,Frumin M,Kikinis R,Jolesz FA,McCarley RW,Shenton ME

    更新日期：2005-07-15 00:00:00

  • Canonical Granger causality between regions of interest.

    abstract：:Estimating and modeling functional connectivity in the brain is a challenging problem with potential applications in the understanding of brain organization and various neurological and neuropsychological conditions. An important objective in connectivity analysis is to determine the connections between regions of int...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.06.056

    authors： Ashrafulla S,Haldar JP,Joshi AA,Leahy RM

    更新日期：2013-12-01 00:00:00

  • Novel artefact removal algorithms for co-registered EEG/fMRI based on selective averaging and subtraction.

    abstract：:Co-registered EEG and functional MRI (EEG/fMRI) is a potential clinical tool for planning invasive EEG in patients with epilepsy. In addition, the analysis of EEG/fMRI data provides a fundamental insight into the precise physiological meaning of both fMRI and EEG data. Routine application of EEG/fMRI for localization ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.09.022

    authors： de Munck JC,van Houdt PJ,Gonçalves SI,van Wegen E,Ossenblok PP

    更新日期：2013-01-01 00:00:00

  • Combining task-evoked and spontaneous activity to improve pre-operative brain mapping with fMRI.

    abstract：:Noninvasive localization of brain function is used to understand and treat neurological disease, exemplified by pre-operative fMRI mapping prior to neurosurgical intervention. The principal approach for generating these maps relies on brain responses evoked by a task and, despite known limitations, has dominated clini...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.09.030

    authors： Fox MD,Qian T,Madsen JR,Wang D,Li M,Ge M,Zuo HC,Groppe DM,Mehta AD,Hong B,Liu H

    更新日期：2016-01-01 00:00:00

  • Locating the initial stages of speech-sound processing in human temporal cortex.

    abstract：:It is commonly assumed that, in the cochlea and the brainstem, the auditory system processes speech sounds without differentiating them from any other sounds. At some stage, however, it must treat speech sounds and nonspeech sounds differently, since we perceive them as different. The purpose of this study was to deli...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.01.004

    authors： Uppenkamp S,Johnsrude IS,Norris D,Marslen-Wilson W,Patterson RD

    更新日期：2006-07-01 00:00:00

  • Enhancing reproducibility of fMRI statistical maps using generalized canonical correlation analysis in NPAIRS framework.

    abstract：:Common fMRI data processing techniques usually minimize a temporal cost function or fit a temporal model to extract an activity map. Here, we focus on extracting a highly, spatially reproducible statistical parametric map (SPM) from fMRI data using a cost function that does not depend on a model of the subjects' tempo...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.01.137

    authors： Afshin-Pour B,Hossein-Zadeh GA,Strother SC,Soltanian-Zadeh H

    更新日期：2012-05-01 00:00:00

  • Feature selection and classification of imbalanced datasets: application to PET images of children with autistic spectrum disorders.

    abstract：:Learning with discriminative methods is generally based on minimizing the misclassification of training samples, which may be unsuitable for imbalanced datasets where the recognition might be biased in favor of the most numerous class. This problem can be addressed with a generative approach, which typically requires ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.05.011

    authors： Duchesnay E,Cachia A,Boddaert N,Chabane N,Mangin JF,Martinot JL,Brunelle F,Zilbovicius M

    更新日期：2011-08-01 00:00:00

  • Attentional modulation of stimulus representation in human fronto-parietal cortex.

    abstract：:Evidence from primates suggests that prefrontal and parietal regions selectively represent information that is relevant for current behavior. In humans, whilst functional imaging has shown that fronto-parietal areas are activated by a range of different cognitive demands, the actual content of representation remains u...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.06.066

    authors： Thompson R,Duncan J

    更新日期：2009-11-01 00:00:00

  • Multifaceted genomic risk for brain function in schizophrenia.

    abstract：:Recently, deriving candidate endophenotypes from brain imaging data has become a valuable approach to study genetic influences on schizophrenia (SZ), whose pathophysiology remains unclear. In this work we utilized a multivariate approach, parallel independent component analysis, to identify genomic risk components ass...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.03.022

    authors： Chen J,Calhoun VD,Pearlson GD,Ehrlich S,Turner JA,Ho BC,Wassink TH,Michael AM,Liu J

    更新日期：2012-07-16 00:00:00

  • Brain activity reflects the predictability of word sequences in listened continuous speech.

    abstract：:Natural speech builds on contextual relations that can prompt predictions of upcoming utterances. To study the neural underpinnings of such predictive processing we asked 10 healthy adults to listen to a 1-h-long audiobook while their magnetoencephalographic (MEG) brain activity was recorded. We correlated the MEG sig...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.116936

    authors： Koskinen M,Kurimo M,Gross J,Hyvärinen A,Hari R

    更新日期：2020-10-01 00:00:00

  • Projecting out muscle artifacts from TMS-evoked EEG.

    abstract：:Transcranial magnetic stimulation combined with electroencephalography is a powerful tool for probing cortical excitability and connectivity; we can perturb one brain area and study the reactions at the stimulated and interconnected sites. When stimulating areas near cranial muscles, their activation produces a large ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.11.041

    authors： Mäki H,Ilmoniemi RJ

    更新日期：2011-02-14 00:00:00

  • Locally regularized spatiotemporal modeling and model comparison for functional MRI.

    abstract：:In this work we treat fMRI data analysis as a spatiotemporal system identification problem and address issues of model formulation, estimation, and model comparison. We present a new model that includes a physiologically based hemodynamic response and an empirically derived low-frequency noise model. We introduce an e...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.2001.0870

    authors： Purdon PL,Solo V,Weisskoff RM,Brown EN

    更新日期：2001-10-01 00:00:00

  • Cortical control of normal gait and precision stepping: an fNIRS study.

    abstract：:Recently, real time imaging of the cortical control of gait became possible with functional near-infrared spectroscopy (fNIRS). So far, little is known about the activations of various cortical areas in more complex forms of gait, such as precision stepping. From previous work on animals and humans one would expect pr...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.04.070

    authors： Koenraadt KL,Roelofsen EG,Duysens J,Keijsers NL

    更新日期：2014-01-15 00:00:00

  • Visual cortex signals a mismatch between regularity of auditory and visual streams.

    abstract：:Understanding how humans code for and respond to environmental uncertainty/regularity is a question shared by current computational and neurobiological approaches to human cognition. To date, studies investigating neurobiological systems that track input uncertainty have examined responses to uni-sensory streams. It i...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.05.028

    authors： Andric M,Davis B,Hasson U

    更新日期：2017-08-15 00:00:00

  • Detection of optical neuronal signals in the visual cortex using continuous wave near-infrared spectroscopy.

    abstract：:Near-infrared spectroscopy (NIRS) measures slow hemodynamic signals noninvasively to indirectly infer the neuronal activity in the brain. However, it remains a controversy on whether this optical measurement technique can detect the optical neuronal signal, which reflects the optical changes directly associated with n...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.11.003

    authors： Sun B,Zhang L,Gong H,Sun J,Luo Q

    更新日期：2014-02-15 00:00:00

  • Forgiveness and cognitive control - Provoking revenge via theta-burst-stimulation of the DLPFC.

    abstract：:In order to act in a socially acceptable way, the ability to forgive is indispensable. It has been suggested that forgiveness relies on cognitive control, more specifically inhibition. In this study, we combined an ultimatum game (UG) and a dictator game (DG) with inhibitory, continuous theta-burst stimulation (cTBS; ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.08.065

    authors： Maier MJ,Rosenbaum D,Haeussinger FB,Brüne M,Enzi B,Plewnia C,Fallgatter AJ,Ehlis AC

    更新日期：2018-12-01 00:00:00

  • Effective auditory-verbal encoding activates the left prefrontal and the medial temporal lobes: A generalization to illiterate subjects.

    abstract：:Recent event-related FMRI studies indicate that the prefrontal (PFC) and the medial temporal lobe (MTL) regions are more active during effective encoding than during ineffective encoding. The within-subject design and the use of well-educated young college students in these studies makes it important to replicate thes...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1006/nimg.1999.0446

    authors： Petersson KM,Reis A,Castro-Caldas A,Ingvar M

    更新日期：1999-07-01 00:00:00

  • Unified segmentation based correction of R1 brain maps for RF transmit field inhomogeneities (UNICORT).

    abstract：:Quantitative mapping of the longitudinal relaxation rate (R1=1/T1) in the human brain enables the investigation of tissue microstructure and macroscopic morphology which are becoming increasingly important for clinical and neuroimaging applications. R1 maps are now commonly estimated from two fast high-resolution 3D F...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.10.023

    authors： Weiskopf N,Lutti A,Helms G,Novak M,Ashburner J,Hutton C

    更新日期：2011-02-01 00:00:00

  • Effects of lactate on the early visual cortex of non-human primates, investigated by pharmaco-MRI and neurochemical analysis.

    abstract：:In contrast to the limited use of functional magnetic resonance imaging (fMRI) in clinical diagnostics, it is currently a mainstay of neuroimaging in clinical and basic brain research. However, its non-invasive use in combination with its high temporal and spatial resolution would make fMRI a perfect diagnostic tool. ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2012.02.082

    authors： von Pföstl V,Li J,Zaldivar D,Goense J,Zhang X,Serr N,Logothetis NK,Rauch A

    更新日期：2012-05-15 00:00:00

  • Predictive perception of self-generated movements: Commonalities and differences in the neural processing of tool and hand actions.

    abstract：:Tool use is one of the most remarkable skills of the human species, enabling complex interactions with the environment. To establish such interactions, we predict the sensory consequences of our actions based on a copy of the motor command (efference copy), leading to an attenuated perception and neural suppression of...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116309

    authors： Pazen M,Uhlmann L,van Kemenade BM,Steinsträter O,Straube B,Kircher T

    更新日期：2020-02-01 00:00:00

  • Functional atlas of the awake rat brain: A neuroimaging study of rat brain specialization and integration.

    abstract：:Connectivity-based parcellation approaches present an innovative method to segregate the brain into functionally specialized regions. These approaches have significantly advanced our understanding of the human brain organization. However, parallel progress in animal research is sparse. Using resting-state fMRI data an...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.07.007

    authors： Ma Z,Perez P,Ma Z,Liu Y,Hamilton C,Liang Z,Zhang N

    更新日期：2018-04-15 00:00:00

  • Characterizing spatial and temporal features of autobiographical memory retrieval networks: a partial least squares approach.

    abstract：:Conway (Conway, M.A., 1992. A structural model of autobiographical memory. In: Conway, M.A., Spinnler, H., Wagenaar, W.A. (Eds.), Theoretical Perspectives on Autobiological Memory. Kluwer Academic Publishers, Dordrecht, The Netherlands, pp. 167-194) proposed that two types of autobiographical memories (AMs) exist with...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.08.007

    authors： Addis DR,McIntosh AR,Moscovitch M,Crawley AP,McAndrews MP

    更新日期：2004-12-01 00:00:00

  • Dissociable neural representations of grammatical gender in Broca's area investigated by the combination of satiation and TMS.

    abstract：:Along with meaning and form, words can be described on the basis of their grammatical properties. Grammatical gender is often used to investigate the latter as it is a grammatical property that is independent of meaning. The left inferior frontal gyrus (IFG) has been implicated in the encoding of grammatical gender, b...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.04.097

    authors： Cattaneo Z,Devlin JT,Vecchi T,Silvanto J

    更新日期：2009-08-15 00:00:00

  • A longitudinal diffusion tensor imaging study on Wallerian degeneration of corticospinal tract after motor pathway stroke.

    abstract：:Wallerian degeneration of the corticospinal tract (CST) after motor pathway ischemic stroke can be characterized by diffusion tensor imaging (DTI). However, the dynamic evolution of the diffusion indices in the degenerated CST has not previously been completely identified. We investigated this dynamic evolution and th...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.04.066

    authors： Yu C,Zhu C,Zhang Y,Chen H,Qin W,Wang M,Li K

    更新日期：2009-08-15 00:00:00

  • Separate neural systems for processing action- or non-action-related sounds.

    abstract：:The finding of a multisensory representation of actions in a premotor area of the monkey brain suggests that similar multimodal action-matching mechanisms may also be present in humans. Based on the existence of an audiovisual mirror system, we investigated whether sounds referring to actions that can be performed by ...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.neuroimage.2004.09.025

    authors： Pizzamiglio L,Aprile T,Spitoni G,Pitzalis S,Bates E,D'Amico S,Di Russo F

    更新日期：2005-02-01 00:00:00

  • Associations between dopamine D2 receptor availability and BMI depend on age.

    abstract：OBJECTIVE:The dopamine D2/3 receptor subtypes (DRD2/3) are the most widely studied neurotransmitter biomarker in research on obesity, but results to date have been inconsistent, have typically involved small samples, and have rarely accounted for subjects' ages despite the large impact of age on DRD2/3 levels. We aimed...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.05.044

    authors： Dang LC,Samanez-Larkin GR,Castrellon JJ,Perkins SF,Cowan RL,Zald DH

    更新日期：2016-09-01 00:00:00