当前位置： SCI文献检索 > JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY期刊下所有文献 > Diagnostic Value of Global Cardiac Strain in Patients With Myocarditis.

Diagnostic Value of Global Cardiac Strain in Patients With Myocarditis.

Abstract：

BACKGROUND:Cardiac strain represents an imaging biomarker of contractile dysfunction. PURPOSE:The purpose of this study was to investigate the diagnostic value of cardiac strain obtained by feature-tracking cardiac magnetic resonance (MR) in acute myocarditis. MATERIALS AND METHODS:Cardiac MR examinations of 46 patients with myocarditis and preserved ejection fraction at acute phase and follow-up were analyzed along with cardiac MR of 46 healthy age- and sex-matched controls. Global circumferential strain and global radial strain were calculated for each examination, along with myocardial edema and late gadolinium enhancement, and left ventricle functional parameters, through manual contouring of the myocardium. Correlations were assessed using Spearman ρ. Wilcoxon and Mann-Whitney U test were used to assess differences between data. Receiver operating characteristics curves and reproducibility were obtained to assess the diagnostic role of strain parameters. RESULTS:Global circumferential strain was significantly lower in controls (median, -20.4%; interquartile range [IQR], -23.4% to -18.7%) than patients in acute phase (-18.4%; IQR, -21.0% to -16.1%; P = 0.001) or at follow-up (-19.2%; IQR, -21.5% to -16.1%; P = 0.020). Global radial strain was significantly higher in controls (82.4%; IQR, 62.8%-104.9%) than in patients during the acute phase (65.8%; IQR, 52.9%-79.5%; P = 0.001). Correlations were found between global circumferential strain and global radial strain in all groups (acute, ρ = -0.580, P < 0.001; follow-up, ρ = -0.399, P = 0.006; controls, ρ = -0.609, P < 0.001), and between global circumferential strain and late gadolinium enhancement only in myocarditis patients (acute, ρ = 0.035, P = 0.024; follow-up, ρ = 0.307, P = 0.038). CONCLUSIONS:Cardiac strain could potentially have a role in detecting acute myocarditis in low-risk acute myocarditis patients where cardiac MR is the main diagnosing technique.

journal_name

J Comput Assist Tomogr

journal_title

Journal of computer assisted tomography

authors

Secchi F,Monti CB,Alì M,Carbone FS,Cannaò PM,Sardanelli F

doi

10.1097/RCT.0000000000001062

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

591-598

issue

eissn

0363-8715

issn

1532-3145

pii

00004728-202007000-00021

journal_volume

pub_type

杂志文章

在线工具

Diagnostic Value of Global Cardiac Strain in Patients With Myocarditis.