Perirenal fat invasion on renal cell carcinoma: evaluation with multidetector computed tomography-multivariate analysis.

Abstract:

OBJECTIVE:The objective of this study was to assess the accuracy of multidetector computed tomography (CT) in diagnosing perinephric (PN) and/or renal sinus (RS) fat invasion in patients with renal cell carcinoma (RCC), with reference to the CT findings predictive for the diagnosis of invasion. METHODS:This was a retrospective study of 48 RCCs. Examinations were performed on a 16-row CT scanner, including unenhanced and 3-phase contrast-enhanced CT scanning. Unenhanced transverse images and multiplanar reformations of each contrast-enhanced CT phase were evaluated. The predictive value of CT findings in diagnosing PN and/or RS fat invasion was determined using multivariate logistic regression analysis. RESULTS:The CT findings that were most predictive for the diagnosis of PN fat invasion were the presence of contrast-enhancing nodules in the PN fat and tumoral margins. Invasion of the pelvicaliceal system was the most significant predictor in the diagnosis of RS fat invasion. CONCLUSIONS:Multidetector CT provides satisfactory results in detecting PN and/or RS fat invasion in RCC.

journal_name

J Comput Assist Tomogr

authors

Tsili AC,Goussia AC,Baltogiannis D,Astrakas L,Sofikitis N,Malamou-Mitsi V,Argyropoulou MI

doi

10.1097/RCT.0b013e318283bc8e

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

450-7

issue

3

eissn

0363-8715

issn

1532-3145

pii

00004728-201305000-00022

journal_volume

37

pub_type

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