Abstract:
PURPOSE:This study was designed to examine the use of quantitative magnetization transfer imaging (MTI) in naturally occurring globoid cell leukodystrophy (GLD) in the Cairn terrier. METHOD:A model of GLD was established via a breeding colony, and a total of seven animals were studied with MTI, including two dogs with GLD, one of which underwent whole-body irradiation (725 cGy) and bone marrow transplantation from a genotypically normal littermate. The remaining dogs served as untreated, irradiated, and unirradiated controls. RESULTS:Region-of-interest (ROI) analysis of the MTI showed a decrease in MT ratio (MTR) in the internal capsule of the untreated/affected dog compared with age-matched controls but revealed similar results in the two other study animals. On MT contour plotting, inside-to-out gradients of MTR mimicked the demyelination pathology of the disease in the untreated/affected dog. CONCLUSION:MT contour plotting demonstrated patterns of MT abnormality in the untreated/affected dog that were consistent with histopathology, establishing a clear relationship between pathology-proven demyelination and MTR as well as a striking contrast to the patterns of radiation damage.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
McGowan JC,Haskins M,Wenger DA,Vite Cdoi
10.1097/00004728-200003000-00025keywords:
subject
Has Abstractpub_date
2000-03-01 00:00:00pages
316-21issue
2eissn
0363-8715issn
1532-3145pii
00004728-200003000-00025journal_volume
24pub_type
杂志文章abstract:PURPOSE:The purpose of this study was to compare the preoperative detectability of hepatocellular carcinomas (HCCs) using combined T2-weighted and dynamic gadolinium-enhanced MRI and combined CT during arterial portography (CTAP) and CT hepatic arteriography (CTHA). METHOD:Thirty-three patients with 43 HCCs underwent ...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章
doi:10.1097/00004728-200109000-00018
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:Electron beam CT (EBCT)-derived coronary artery calcium scores correlate with the extent of atherosclerosis, but there is a substantial variance about the general relationship between coronary calcification and coronary atherosclerosis. The relationship between calcification and atherosclerosis may also differ ...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004728-199803000-00008
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:Phase-contrast cine magnetic resonance imaging (PC-MRI) is a widely used technique for determination of possible communication of arachnoid cysts (ACs). Three-dimensional (3D) sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-SPACE) technique is a relatively new ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000751
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the computed tomography (CT) findings and correlate pulmonary function tests (PFTs) of silicosis patients with emphasis on the findings in lung transplantation (LTX) recipients. METHODS:We studied the chest CT scans from 82 marble workers exposed to artificial stone dust...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000454
更新日期:2016-11-01 00:00:00
abstract::Transorbital penetration of the cranial cavity by a small wooden object can pass unnoticed, while producing severe, life-threatening consequences. The occurrence of a traumatic intracranial aneurysm secondary to a wooden foreign body has not been reported previously in the English literature, to our knowledge. Familia...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198705000-00030
更新日期:1987-05-01 00:00:00
abstract::Magnetic susceptibility variations due to the presence of iron in neural tissue can result in a shift of local resonance frequency, decreased T2 resulting from water diffusion through local field gradients, and line broadening due to field inhomogeneity within a voxel. In this study, modified spin echo phase contrast ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198803000-00014
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:The purpose of this work was to define the characteristic MR features of colorectal mucinous carcinomas and to correlate the mucin pool with the signal intensity of this tumor. METHOD:MRI of 12 cases of pathologically proven colorectal carcinoma containing mucin was evaluated. We analyzed the signal intensity ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199903000-00021
更新日期:1999-03-01 00:00:00
abstract::Computed tomography has had an increasing role in the evaluation of patients after blunt trauma. Important findings in thoracic trauma include acute traumatic aortic injury, pneumothorax, hemothorax, pulmonary contusions and lacerations, mediastinal hematoma, and diaphragmatic rupture. The solid abdominal viscera may ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/01.rct.0000120858.80935.59
更新日期:2004-07-01 00:00:00
abstract::A new 6 mm collimator for the EMI CT5000/5005 scanner is described. It consists of a narrower tube side and detector side collimator that can be set up in less than 5 min. The applications are primarily for the orbit and parasellar area. Future applications with the aid of new software include coronal reconstruction. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197807000-00029
更新日期:1978-07-01 00:00:00
abstract:PURPOSE:The purpose of this work was to evaluate patients with carpal tunnel syndrome (CTS) using a low-field extremity MR system (E-MRI: 0.2 T). METHOD:Twenty-two patients with typical findings of CTS and 30 control persons were imaged on an E-MRI. Axial T2-weighted turbo SE (TSE), T1-weighted SE sequences, and 2D GR...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200101000-00026
更新日期:2001-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We delivered the saline chaser via a spiral flow-generating tube or a conventional connecting tube and compared arterial enhancement at computed tomography angiography (CTA) of the lower extremities. MATERIALS AND METHODS:We randomly assigned 100 patients whose ankle bronchial pressure index o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,随机对照试验
doi:10.1097/RCT.0000000000000292
更新日期:2015-11-01 00:00:00
abstract::The design of a high resolution positron emission tomograph is described. The scanner has four rings of detectors with an inside diameter of 38 cm and produces seven simultaneous slices, including three cross-slices. Each ring contains 128 bismuth germanate scintillation detectors with dimensions of 8.25 x 20 x 35 mm;...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198002000-00002
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVE:The aim of our study was to evaluate the diagnostic performance of cardiac computed tomography (CCT) in the evaluation of coronary artery stenosis in patients with ascending aorta aneurysm detected at transthoracic echocardiography. METHODS:We conducted a retrospective analysis of patients with an aneurysm 4...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000380
更新日期:2016-05-01 00:00:00
abstract::Hepatic actinomycosis is an uncommon entity that forms communicating abscesses and fistulae. A case is presented in which findings on ultrasound, CT, and percutaneous injection of the abscess all reflected the pathologic process. Biopsy by thin-needle aspiration under CT guidance afforded prompt, accurate diagnosis an...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198603000-00035
更新日期:1986-03-01 00:00:00
abstract:PURPOSE:Typically, the final step in volume registration is the reslicing of the volume of interest. The purpose of this work is to examine the effects of this reslicing on functional MRI (fMRI) data using different interpolation methods. METHOD:Functional whole-brain echo planar imaging (EPI) volumes were resliced us...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199709000-00029
更新日期:1997-09-01 00:00:00
abstract::Three cases of hemorrhagic nerve sheath tumors of the scalp are presented with emphasis on CT findings. Each mass produced a mixed pattern of CT density due to the combination of tumor and hemorrhage within it. The CT findings were remarkably similar in the three patients and included a calvarial abnormality underlyin...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198503000-00008
更新日期:1985-03-01 00:00:00
abstract::A 45-year-old patient with focal intrahepatic extramedullary hematopoiesis is presented in which the liver was imaged by CT, ultrasound, and MR. The appearance of the lesions on MR consisted of slightly increased signal on T2-weighted images with heterogeneous enhancement of some of the lesions during bolus infusion o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::Fibrodysplasia ossificans progressiva is a rare disorder characterized by progressive heterotopic bone formation in connective tissue and muscle in association with congenital skeletal anomalies. The disease usually leads to extensive immobility and eventual disability. We report the magnetic resonance findings in a b...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199003000-00035
更新日期:1990-03-01 00:00:00
abstract::Aeration of the middle turbinate, termed "concha bullosa," is a common anatomical variant of intranasal anatomy. Of 320 patients evaluated for sinus disease with coronal CT, 34% had concha bullosa on at least one side. The overall incidence of inflammatory disease in the ostiomeatal complex in these symptomatic patien...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198809010-00012
更新日期:1988-09-01 00:00:00
abstract::Repeat examinations in a de novo patient with Wilson disease revealed an expansion of decreased signal intensities in the basal ganglia on T2-weighted imaging after initiation of copper trapping therapy. Since marked clinical improvement was associated with continued urinary copper excretion, iron depositioning in exc...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199507000-00026
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine the effects of dose reduction and iterative reconstruction (IR) on pulmonary nodule volumetry. METHODS:In this prospective study, 25 patients scheduled for follow-up of pulmonary nodules were included. Computed tomography acquisitions were acquired at 4 dose levels with ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000408
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:We retrospectively evaluated whether multi-detector row computed tomography (MDCT) could contribute to the early detection of contralateral breast cancer in women with a diagnosis of breast cancer and no suspicious lesions on a mammogram or an ultrasonogram of the contralateral breast. METHODS:A total of 518...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181f8c8fa
更新日期:2011-01-01 00:00:00
abstract::Implementation of an accurate, reliable index of cost effectiveness would help to advance technology assessment and reimbursement of MR imaging procedures, including gadolinium enhancement. To this end, an objective, consensual measure that satisfies the need for "gold-standard" confirmation of diagnostic impressions ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199301001-00008
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:The purpose of this work is to describe the CT and MR appearance of primary malignant fibrous histiocytoma (MFH) of the chest wall. METHOD:Eleven men and eight women (45-76 years old) with primary MFH of the chest wall who underwent both CT and MRI were enrolled, and the imaging interpretation was retrospectiv...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200207000-00015
更新日期:2002-07-01 00:00:00
abstract::Three patients with various pectus excavatum deformities in whom radiographic findings suggested hilar and mediastinal masses are presented. Computed tomography of the chest yielded valuable diagnostic information and made it possible to exclude the existence of these masses. Compression deformity of the heart and gre...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197910000-00004
更新日期:1979-10-01 00:00:00
abstract::A case of isolated spinal cord hemangioblastoma with associated extensive syringohydromyelia, which was evaluated by myelography, postmyelographic CT, magnetic resonance (MR), and angiography is presented. The specific preoperative and postoperative advantages of MR are given as well as a brief review of the literatur...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198805010-00028
更新日期:1988-05-01 00:00:00
abstract::Fast MR techniques and the application of water-soluble contrast agents allow the simultaneous examination of renal morphology and the functional aspects of glomerular filtration using bolus injections of Gd-DTPA. Spatial resolution is sufficient to resolve individual renal pyramids, but the quantitative examination o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199109000-00002
更新日期:1991-09-01 00:00:00
abstract::The computed tomographic (CT) characteristics of intraabdominal tuberculosis are not specific. A recent article from South Africa proposed a set of criteria that included high density ascites and mesenteric involvement, consisting of thickening and adenopathy, as possible criteria for the diagnosis of tuberculous peri...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198406000-00014
更新日期:1984-06-01 00:00:00
abstract::The authors report three cases of abnormal chest radiography mimicking mediastinal masses. These radiographic findings were unrelated to any pathology, were discovered in asymptomatic patients, and must be considered consequences of unusually narrow thoracic inlets. Mean and standard deviations of the anteroposterior ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198607000-00011
更新日期:1986-07-01 00:00:00
abstract:PURPOSE:To describe magnetic resonance (MR) imaging and MR cholangiopancreatography (MRCP) findings in gallbladder carcinoma, and to correlate these findings with available surgical and biopsy information. METHODS:Preoperative MR images (T1-weighted spin-echo, T2-weighted fast spin-echo, single shot fast spin-echo, an...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200205000-00015
更新日期:2002-05-01 00:00:00