Abstract:
BACKGROUND AND AIMS:To prospectively determine the accuracy of liver fat quantification with magnetic resonance imaging (MRI). PATIENTS AND METHODS:The population consisted of 40 patients (mean age, 52.5 years; range, 23-78 years). The same day, all patients underwent MRI and ultrasonography-guided liver biopsy. The histological evaluation of steatosis was performed by an experienced liver pathologist blinded to the MRI results. On T1-weighted in- and opposed-phase images, one radiologist, experienced in abdominal imaging, blinded to the clinical and pathological results, recorded signal intensity (SI) by mean regions of interest placed at same locations in both phases. Fat-water ratio was obtained by dividing SI of liver in opposed-phase sequence by SI of liver in in-phase sequence. The fat-water ratio and the histological grade of steatosis were compared by linear regression. Receiver operating characteristic curve was used to define the sensitivity and specificity of fat-water ratio as a diagnostic tool for evaluation of steatosis. RESULTS:Diagnoses were nonalcoholic fatty liver disease (n = 25), alcoholic liver disease (n = 10), cholangiopathy (n = 2), and autoimmune hepatitis (n = 3). Fatty liver infiltration was present in 80% of patients. The mean (SD) percentage of fatty hepatocytes was 38.7% (29.2). Fat-water ratio and steatosis grade were highly correlated (r = 0.852, P < 0.0001). Sensitivity and specificity of fat-water ratio to detect fatty infiltration greater than 20% were 96% and 93%, respectively. CONCLUSIONS:This prospective study demonstrates that MRI can be proposed as a noninvasive method to screen and quantify liver steatosis.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Mennesson N,Dumortier J,Hervieu V,Milot L,Guillaud O,Scoazec JY,Pilleul Fdoi
10.1097/RCT.0b013e318199d883subject
Has Abstractpub_date
2009-09-01 00:00:00pages
672-7issue
5eissn
0363-8715issn
1532-3145pii
00004728-200909000-00004journal_volume
33pub_type
杂志文章abstract::A hepatic specific contrast agent was used in an attempt to detect a biopsy-proven hepatoma. This lesion had been missed by routine computed tomography and was poorly detected with the hepatic specific contrast agent EOE 13. It was also poorly detected by technetium-sulfur colloid hepatic scintigraphy. The true extent...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198310000-00032
更新日期:1983-10-01 00:00:00
abstract:OBJECTIVE:To describe the magnetic resonance imaging characteristics of supratentorial ependymomas. METHODS:The magnetic resonance imaging and computed tomography imaging characteristics of 49 cases of supratentorial ependymomas were analyzed retrospectively. The location, size, degree of perilesional edema, gross app...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001080
更新日期:2020-09-01 00:00:00
abstract::The incidence of melanoma has risen dramatically over the past several decades. Oncologists rely on the ability of radiologists to identify subtle radiographic changes representing metastatic and recurrent melanoma in uncommon locations on multidetector computed tomography (MDCT) as the front-line imaging surveillance...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000697
更新日期:2018-05-01 00:00:00
abstract::We reviewed the CT of 20 patients with peripheral lung malignancies in which CT appearance suggested chest wall invasion on the basis of extension of mass around ribs into fat or muscle of the chest wall, or definite bone destruction. We correlated these findings with other radiographic studies and surgical and autops...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198703000-00019
更新日期:1987-03-01 00:00:00
abstract::Seven cases of Poland syndrome were investigated with CT and/or MR to assess the extent of the muscle abnormalities of the shoulder girdle. In all cases the absence of the sternocostal head of the pectoralis major was clearly shown, as were any associated abnormalities of the pectoralis minor, serratus anterior, and l...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199205000-00019
更新日期:1992-05-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the image quality of renal arteries and veins with dual-energy spectral computed tomography (CT) imaging in late arterial phase using 270 and 320 mg I/mL of iodixanol and their influence on renal function. METHODS:A total of 1062 patients underwent renal CT angiogra...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000595
更新日期:2017-09-01 00:00:00
abstract::Primary cardiac lymphomas, defined as those involving only the heart and pericardium, are extremely rare tumors. These tumors are commonly fatal and until recently were rarely diagnosed antemortem. We describe the CT and MR findings in a case of primary lymphoma of the heart currently responding to chemotherapy. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199311000-00025
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:We aim to determine the relationship between leukoaraiosis and carotid artery stenosis. METHODS:Carotid-cerebral multislice computed tomography angiographies of 194 patients (mean age, 63.5 years) were retrospectively evaluated. Presence and severity of leukoaraiosis and carotid artery stenosis were compared...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318284604e
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Electron beam CT (EBCT)-derived coronary artery calcium scores correlate with the extent of atherosclerosis, but there is a substantial variance about the general relationship between coronary calcification and coronary atherosclerosis. The relationship between calcification and atherosclerosis may also differ ...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004728-199803000-00008
更新日期:1998-03-01 00:00:00
abstract::Radiographic evaluation of the penis is difficult and essentially limited to invasive studies. We report cases of idiopathic and iatrogenic corpora cavernosa thromboses diagnosed by magnetic resonance imaging. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198807000-00012
更新日期:1988-07-01 00:00:00
abstract::Serial computed tomography (CT) demonstrated complete resolution of severe periventricular hypodensity occurring in a child after receiving prophylaxis for acute lymphocytic leukemia. The resolution of this encephalopathy suggests that early changes of subacute necrotizing leukoencephalopathy are reversible and CT is ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197809000-00023
更新日期:1978-09-01 00:00:00
abstract:OBJECTIVE:An anomalous origin and course of the coronary arteries can be benign or life threatening. Recently, because of new advances in computed tomography technology, radiologists have begun to interpret the diseases of coronary arteries. We aimed to demonstrate some remarkable anomalies of coronary arteries, some o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,多中心研究
doi:10.1097/01.rct.0000230004.38521.8e
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the Macklin effect in patients with spontaneous pneumomediastinum by multidetector-row computed tomography (MDCT). METHODS:Chest computed tomography (CT) reports between July 2000 and January 2003 at our institution were retrospectively reviewed. Nine patients with s...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000187416.07698.8d
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:X-Ray CT has the potential to provide precise and accurate data from which the mechanical properties of bone can be calculated. Such data would be useful in understanding the response of bone tissue to implants. Various artifacts can, however, degrade accuracy of the data. The aim of this study was to measure t...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199605000-00035
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:To measure the distances between the internal mammary arteries (IMAs) and the sternum for determining a route for parasternal transthoracic interventions. METHODS:Coronal reconstructed multidetector computed tomography images of 202 patients were evaluated to measure the distances between the IMAs and sternu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000172673.17188.69
更新日期:2005-09-01 00:00:00
abstract::Thirty-three patients with rheumatoid arthritis had computed tomographic examination of the craniocervical junction. This demonstrated soft tissue features which have not previously been described in published reports. A low attenuation lesion between the odontoid and the transverse ligament shown in 11 patients was c...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198302000-00006
更新日期:1983-02-01 00:00:00
abstract::We intend to describe the imaging findings of sudden cardiac arrest occurring during computed tomographic (CT) examination and also of impending cardiogenic shock in 4 patients. Despite rare reports of acute cardiac arrest occurring during or shortly after CT scan, CT features are quite characteristic. Familiarity wit...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318250a8bc
更新日期:2012-05-01 00:00:00
abstract::A system of computer programs is described which, for the first time, is able to use computerized tomographic data to automatically locate, measure, and describe anatomical structures of interest with accuracy and consistency. Input to the system consists of any digitized radiographic data. Computer assisted tomograph...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198308000-00008
更新日期:1983-08-01 00:00:00
abstract::A case of calcific tendinitis of the gluteus maximus tendon with cortical erosion is presented. Roentgenography demonstrated calcification on the posterior surface of the proximal femur. Computed tomography showed flame-like appearance of calcific tendinitis and bone erosion. Magnetic resonance imaging showed minimal ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199403000-00030
更新日期:1994-03-01 00:00:00
abstract::A case of hepatic oil embolism following lymphangiography is presented. The computed tomographic appearance is striking and probably distinctive of embolism to the hepatic vascular system. The postulated mechanism for the embolization is discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198106000-00019
更新日期:1981-06-01 00:00:00
abstract:OBJECTIVE:Balò concentric sclerosis is a rare demyelinating disorder. Serial proton magnetic resonance spectroscopic (1H-MRS) studies were carried out to better understand the biochemical changes within concentric lesions. MATERIALS AND METHODS:Five concentric lesions in four patients with Balò concentric sclerosis we...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200109000-00008
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:The purpose of this work was to evaluate the helical CT and CT angiography (CTA) findings of anomalous systemic artery (ASA) to the basal segments of the left lower lobe (LLL). METHOD:Three patients (two had hemoptysis, one was asymptomatic) with blotchy nodular density in the LLL revealed on chest radiographs...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200011000-00026
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare chest digital tomosynthesis (DTS) and multidetector computed tomography (MDCT) for the detection of pulmonary ground-glass opacity (GGO) nodules and estimation of radiation dose using an anthropomorphic chest phantom and simulated nodules. MATERIALS AND METHODS:A male...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318266aa71
更新日期:2012-09-01 00:00:00
abstract::Forty-two patients with hepatocellular carcinoma (HCC) were examined by magnetic resonance (MR) imaging. The presence of tumor was suggested in 41 of 42 cases by a high-intensity area on T2 weighted spin-echo (SE) images with a repetition time (TR) of 1.6 s. Specific findings of HCC such as the presence of a capsule, ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198611000-00012
更新日期:1986-11-01 00:00:00
abstract::Acute infarction of an appendix epiploica resulted in an inflammatory process involving the caudal aspect of the transverse colon and the adjacent greater omentum. Computed tomography demonstrated prominent linear soft tissue densities, an increase in CT number of the involved greater omentum, and posterior displaceme...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198601000-00032
更新日期:1986-01-01 00:00:00
abstract::The clinical records and radiologic findings in six patients with spontaneous (nontraumatic) intrahepatic and subcapsular hemorrhage were reviewed. Four patients had underlying liver lesions (hepatocellular carcinoma and metastasis from B-cell lymphoma in one patient each and hepatic adenoma in two other patients). On...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198805010-00007
更新日期:1988-05-01 00:00:00
abstract::A new 6 mm collimator for the EMI CT5000/5005 scanner is described. It consists of a narrower tube side and detector side collimator that can be set up in less than 5 min. The applications are primarily for the orbit and parasellar area. Future applications with the aid of new software include coronal reconstruction. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197807000-00029
更新日期:1978-07-01 00:00:00
abstract::The unusual CT appearances of a renal neoplasm, which we have described as a "focal" obstructive nephrogram secondary to transitional cell carcinoma, is reported. An explanation of the appearance is postulated. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:Among the various organs that may be affected by hereditary hemorrhagic telangiectasia (HHT), the liver can show various degrees of vascular and parenchymal involvement. The purpose of this prospective study comprising a large series of patients was to reassess the computed tomography (CT) features of hepatic...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200407000-00009
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:Our goal was to determine the number of malignancies detected by thoracic CT in patients with head and neck squamous cell carcinoma (SCCA) in three clinical settings. METHOD:We retrospectively examined 168 thorax CT scans in 93 patients with head and neck SCCA and determined the number of malignancies (second ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199705000-00014
更新日期:1997-05-01 00:00:00