Abstract:
:In less than four months, the total of confirmed cases of COVID-19 was 1,684,833 worldwide. Outcomes among the public of pregnant women with COVID-19 are still unclear. We performed a systematic review and meta-analysis to analyze whether COVID-19 in pregnant women is related to premature birth and birth weight, and to summarize the diagnostic results of neonates born to mothers with COVID-19 for investigating the possibility of vertical transmission. Searches were performed in PubMed, Scopus, LILACS, Web of Science, Google Scholar, Preprints, bioRxiv, and medRxiv. We used the odds ratio (OR) and mean difference (MD) as measure of analysis. Summary estimates were calculated using random effects models. 38 studies were included; data from 279 women were analyzed; 60 patients were diagnosed with COVID-19. The meta-analysis showed no significant association between COVID-19 and preterm delivery (OR = 2.25; 95%CI: 0.96, 5.31; p = 0.06; I² = 0%). No significant relationship was found between birth weight and COVID-19 (MD = -124.16; 95%CI: -260.54, 12.22; p = 0.07; I² = 0%). Among 432 newborns, 10 were reported with positive results for early SARS-CoV-2. Due to the characteristics of the studies, the level of evidence of this meta-analysis was considered very low. COVID-19 in pregnant women may not be associated with the occurrence of preterm deliveries or the birth weight of the newborn children, however the evidence to date is very uncertain. A few reports suggest vertical transmission of SARS-CoV-2 to newborn is possible, but evidence is still uncertain.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Melo GC,Araújo KCGMdoi
10.1590/0102-311x00087320subject
Has Abstractpub_date
2020-01-01 00:00:00pages
e00087320issue
7eissn
0102-311Xissn
1678-4464pii
S0102-311X2020000702001journal_volume
36pub_type
杂志文章,meta分析abstract::The need to evaluate treatment outcomes in mental health services from the user's perspective has been highlighted in the literature. The objective of this study was to compare the perceptions of patients and their families regarding treatment outcomes, in terms of perceived changes in the patient's life. The Percepti...
journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
pub_type: 杂志文章,meta分析,评审
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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pub_type: 杂志文章
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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