Abstract:
:NUPR1 is a transcription factor that has attracted great attention because of its various roles in cancer. Several studies were carried out to determine its molecular targets and mechanism of action to develop novel therapies against cancer. Here, we shed light on the role of NUPR1 in different types of cancer. NUPR1 regulates a complex network of pathways that may be affected by its silencing, which can cause varying effects. Its role in some types of cancer has been reported but remains incompletely understood, whereas its roles in other types of cancers have not been reported yet. Therefore, targeting NUPR1 for cancer treatment remains challenging and risky.
journal_name
Curr Cancer Drug Targetsjournal_title
Current cancer drug targetsauthors
Mansour SMA,Ali SA,Nofal S,Soror SHdoi
10.2174/1568009620666200703152523subject
Has Abstractpub_date
2020-01-01 00:00:00pages
768-778issue
10eissn
1568-0096issn
1873-5576pii
CCDT-EPUB-107874journal_volume
20pub_type
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