Abstract：
:Synthetic amorphous silica (SAS) is widely added to commercial foods as an anticaking agent. Concern about the potential application of nanosized silica in foods has increased as nanomaterials are not intended for use as food additives. This study evaluated the particle size distributions and biological responses of food additive SAS. An accurate, sensitive, and cost-effective analytical method for probing SAS was established, and quantitative analysis of its presence in commercial foods was performed. The results demonstrate that food additive SAS is an aggregated material composed of nanosized particles with nanosized aggregates of silica particles identified in commercial foods. Food additive SAS did not exhibit acute cytotoxicity compared to both general-grade nano (G-nano) and bulk (G-bulk) silica. Moreover, intestinal transport amounts of food additive SAS were significantly lower than for G-nano. Taken together, we find that food additive SAS does not exhibit acute toxicity resulting from nanosized materials.
journal_name
Food Chemjournal_title
Food chemistryauthors
Yu J,Kim YH,Kim HM,Oh JM,Kim YR,Choi SJdoi
10.1016/j.foodchem.2020.127304subject
Has Abstractpub_date
2020-11-30 00:00:00pages
127304eissn
0308-8146issn
1873-7072pii
S0308-8146(20)31166-3journal_volume
331pub_type
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