Transcriptional profiling to identify the key genes and pathways of pterygium.

abstract：:The cost of enzymes makes enzymatic hydrolysis one of the most expensive steps in the production of lignocellulosic ethanol. Diverse studies have used commercial enzyme cocktails assuming that change in total protein concentration during hydrolysis was solely due to adsorption of endo- and exoglucanases onto the subst...

journal_title：PeerJ

authors： Rosales-Calderon O,Trajano HL,Duff SJ

更新日期：2014-06-10 00:00:00

abstract：:Conservation initiatives to protect and restore valued species communities in human-dominated landscapes face challenges linked to their potential costs. Conservation easements on private land may represent a cost-effective alternative to land purchase, but long-term costs to monitor and enforce easements, or defend l...

journal_title：PeerJ

authors： Schuster R,Arcese P

更新日期：2015-08-13 00:00:00

abstract：Background:The diagnosis of congenital heart defects is challenging, especially for what concerns conotruncal anomalies. Indeed, although the screening techniques of fetal cardiac anomalies have greatly improved, the detection rate of conotruncal anomalies still remains low due to the fact that they are associated with...

journal_title：PeerJ

authors： Dell'Oro S,Verderio M,Incerti M,Mastrolia SA,Cozzolino S,Vergani P

更新日期：2018-04-06 00:00:00

abstract：Background:Pandi's mushroom-tongue salamander (Bolitoglossa pandi) is one of the threatened amphibians in South America, as well as a flagship species for the Colombian conservation agenda. This species is endemic to the Andean cloud forests of the western slope of the Cordillera Oriental of Colombia, occurring only in...

journal_title：PeerJ

authors： Angarita-Sierra T,Bonilla-Gómez MA,Sánchez DA,Acosta-Galvis AR,Medina-Ovalle H,Solano-Moreno A,Ulloa-Rengifo S,Guevara-Guevara D,Torres-Ramirez JJ,Curaca-Fierro S,Cabrera-Amaya DM,Infante-Betancour JA,Londoño-Montaño LF,Albarán

更新日期：2020-09-24 00:00:00

abstract：:Background. A "cafeteria" diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to "...

journal_title：PeerJ

authors： Sabater D,Agnelli S,Arriarán S,Romero Mdel M,Fernández-López JA,Alemany M,Remesar X

更新日期：2016-08-03 00:00:00

abstract：:The evolution of the modern human (Homo sapiens) cranium is characterized by a reduction in the size of the feeding system, including reductions in the size of the facial skeleton, postcanine teeth, and the muscles involved in biting and chewing. The conventional view hypothesizes that gracilization of the human feedi...

journal_title：PeerJ

authors： Ledogar JA,Dechow PC,Wang Q,Gharpure PH,Gordon AD,Baab KL,Smith AL,Weber GW,Grosse IR,Ross CF,Richmond BG,Wright BW,Byron C,Wroe S,Strait DS

更新日期：2016-07-26 00:00:00

abstract：:A new p-terphenyl derivative 4″-deoxy-2'-methoxyterphenyllin (1), along with six known p-terphenyl derivatives (2-7), a known flavonoid derivative dechlorochlorflavonin (8) and a known fellutanine A (9), were isolated from the insect-derived strain of the fungus Aspergillus candidus Bdf-2, associated with Blaptica dub...

journal_title：PeerJ

authors： Shan T,Wang Y,Wang S,Xie Y,Cui Z,Wu C,Sun J,Wang J,Mao Z

更新日期：2020-01-02 00:00:00

abstract：:Live trapping is a common tool used to assess demography of small mammals. However, live-trapping is often expensive and stressful to captured individuals. Thus, assessing the relative tradeoffs among study goals, project expenses, and animal well-being is necessary. Here, we evaluated how apparent bias and precision ...

journal_title：PeerJ

authors： Weldy MJ,Wilson TM,Lesmeister DB,Epps CW

更新日期：2019-10-03 00:00:00

abstract：:Mutations that cause an error in the splicing of a messenger RNA (mRNA) can lead to diseases in humans. Various computational models have been developed to recognize the sequence pattern of the splice sites. In recent studies, Convolutional Neural Network (CNN) architectures were shown to outperform other existing mod...

journal_title：PeerJ

authors： Thanapattheerakul T,Engchuan W,Chan JH

更新日期：2020-07-06 00:00:00

abstract：:Evolutionary biology has entered an era of unprecedented amounts of DNA sequence data, as new sequencing technologies such as Massive Parallel Sequencing (MPS) can generate billions of nucleotides within less than a day. The current bottleneck is how to efficiently handle, process, and analyze such large amounts of da...

journal_title：PeerJ

authors： Andermann T,Cano Á,Zizka A,Bacon C,Antonelli A

更新日期：2018-07-13 00:00:00

abstract：:The Hydroporus memnonius species group includes both widespread and range restricted diving beetle taxa in the western Palaearctic, some of which have been divided into a number of geographical subspecies. Of these, Hydroporus necopinatus is distributed in the far west of Europe, from central Spain to southern Britain...

journal_title：PeerJ

authors： Bilton DT,Turner L,Foster GN

更新日期：2017-03-09 00:00:00

abstract：:Haasgat is a primate-rich fossil locality in the northeastern part of the Fossil Hominid Sites of South Africa UNESCO World Heritage Site. Here we report the first hominin identified from Haasgat, a partial maxillary molar (HGT 500), that was recovered from an ex situ calcified sediment block sampled from the locality...

journal_title：PeerJ

authors： Leece AB,Kegley AD,Lacruz RS,Herries AI,Hemingway J,Kgasi L,Potze S,Adams JW

更新日期：2016-05-11 00:00:00

abstract：Background:During a preliminary study, effects of 0, 20, 40, and 60 mM NaCl salinity were assessed on germination rate in relation to electrolyte leakage (EL) in sweet pepper. Results explored significant rises in ethylene evolution from seeds having more EL. It was, therefore, hypothesized that excessive ethylene bios...

journal_title：PeerJ

authors： Ahmed W,Imran M,Yaseen M,Haq TU,Jamshaid MU,Rukh S,Ikram RM,Ali M,Ali A,Maqbool M,Arif M,Khan MA

更新日期：2020-03-27 00:00:00

abstract：:Herein, we identified the tomato SlMYB102 gene as a MYB family transcription factor of the R2R3-MYB subfamily. We additionally determined that the SlMYB102 promoter region contains photoresponsive, abiotic stress-responsive, and hormone-responsive regulatory elements, and we detected higher SlMYB102 expression in the ...

journal_title：PeerJ

authors： Wang M,Hao J,Chen X,Zhang X

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Assessing psychological pain has been recommended as an integral part of a comprehensive suicide risk assessment. The Psychache Scale, an established measure of psychological pain, does not specify a time frame for when pain is experienced, which may inadvertently increase the likelihood of identifying indiv...

journal_title：PeerJ

authors： Meerwijk EL,Weiss SJ

更新日期：2017-06-22 00:00:00

abstract：Background:Leucojum aestivum L. is an important medicinal plant which produces Amaryllidaceae alkaloids, especially galanthamine and lycorine. Research is currently exploring the possibility of producing these alkaloids using biotechnological methods, including in vitro cultures. The biosynthesis of alkaloids may be af...

journal_title：PeerJ

authors： Ptak A,Morańska E,Skrzypek E,Warchoł M,Spina R,Laurain-Mattar D,Simlat M

更新日期：2020-03-16 00:00:00

abstract：:Weevils (Coleoptera: Curculionoidea) represent one of the most diverse groups of organisms on Earth; interactions with their host plants have been recognized to play a central role in their remarkable diversity, yet the exact mechanisms and factors still remain poorly understood. Using phylogenetic comparative analyse...

journal_title：PeerJ

authors： Hernández-Vera G,Toševski I,Caldara R,Emerson BC

更新日期：2019-03-20 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two late onset neurodegenerative diseases, have been shown to share overlapping cellular pathologies and genetic origins. Studies suggest that a hexanucleotide repeat expansion in the first intron of the C9orf72 gene is the most common cause of fam...

journal_title：PeerJ

authors： Iyer S,Subramanian V,Acharya KR

更新日期：2018-10-17 00:00:00

abstract：:Although neonicotinoids are targeted at insects, their predominant use as a seed dressing and their long persistence in soils mean that non-target soil organisms such as earthworms are likely to be chronically exposed to them. Chronic exposure may pose risks that are not evaluated in most toxicity tests. We experiment...

journal_title：PeerJ

authors： Basley K,Goulson D

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Estimating volumes and masses of total body components is important for the study and treatment monitoring of nutrition and nutrition-related disorders, cancer, joint replacement, energy-expenditure and exercise physiology. While several equations have been offered for estimating total body components from M...

journal_title：PeerJ

authors： Lacoste Jeanson A,Dupej J,Villa C,Brůžek J

更新日期：2017-05-18 00:00:00

abstract：:Despite the local and global importance of forests, deforestation is driven by various socio-economic and biophysical factors continues in many countries. In Nepal, in response to massive deforestation, the community forestry program has been implemented to reduce deforestation and support livelihoods. After four deca...

journal_title：PeerJ

authors： Shrestha S,Shrestha UB,Bawa K

更新日期：2018-05-29 00:00:00

abstract：:Antibiotic resistance in our pathogens is medicine's climate change: caused by human activity, and resulting in more extreme outcomes. Resistance emerges in microbial populations when antibiotics act on phenotypic variance within the population. This can arise from either genotypic diversity (resulting from a mutation...

journal_title：PeerJ

authors： Kurenbach B,Hill AM,Godsoe W,van Hamelsveld S,Heinemann JA

更新日期：2018-10-12 00:00:00

abstract：BACKGROUND:The purpose of this study is to provide a report on scientific production during the period 2010-2014 in order to identify the major topics as well as the predominant actors (journals, countries, continents) involved in the field of eye disease. METHODS:A PubMed search was carried out to extract articles re...

journal_title：PeerJ

authors： Boudry C,Denion E,Mortemousque B,Mouriaux F

更新日期：2016-01-07 00:00:00

abstract：:The study of material collected during routine monitoring surveys dealing with oil extraction and aquaculture in waters off Myanmar (North Andaman Sea) and in the Gulf of Thailand, respectively, allowed us to analyse the taxonomy and diversity of the polychaete genus Terebellides (Annelida). Three species were found, ...

journal_title：PeerJ

authors： Parapar J,Moreira J,Martin D

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Mycobacterium avium subsp. hominissuis (MAH) is an emerging opportunistic human pathogen. It can cause pulmonary infections, lymphadenitis and disseminated infections in immuno-compromised patients. In addition, MAH is widespread in the environment, since it has been isolated from water, soil or dust. In rec...

journal_title：PeerJ

authors： Sanchini A,Dematheis F,Semmler T,Lewin A

更新日期：2017-01-03 00:00:00

abstract：Background:Dinoflagellates have the potential to pose severe ecological and economic damages to aquatic ecosystems. It is therefore largely needed to understand the causes and consequences of distribution patterns of dinoflagellate communities in order to manage potential environmental problems. However, a majority of ...

journal_title：PeerJ

authors： Gao Y,Chen Y,Xiong W,Li S,Zhan A

更新日期：2019-04-09 00:00:00

abstract：:Low intensity repetitive magnetic stimulation of neural tissue modulates neuronal excitability and has promising therapeutic potential in the treatment of neurological disorders. However, the underpinning cellular and biochemical mechanisms remain poorly understood. This study investigates the behavioural effects of l...

journal_title：PeerJ

authors： Hong I,Garrett A,Maker G,Mullaney I,Rodger J,Etherington SJ

更新日期：2018-03-12 00:00:00

abstract：:Although the cellular and molecular responses to exposure to relatively high temperatures (acute thermal stress or heat shock) have been studied previously, only sparse empirical evidence of how it affects cold-water species is available. As climate change becomes more pronounced in areas such as the Western Antarctic...

journal_title：PeerJ

authors： González-Aravena M,Kenny NJ,Osorio M,Font A,Riesgo A,Cárdenas CA

更新日期：2019-12-03 00:00:00

abstract：:Much genomic-scale, especially transcriptomic, data on spider phylogeny has accumulated in the last few years. These data have recently been used to investigate the diverse architectures and the origin of spider webs, concluding that the ancestral spider spun no foraging web, that spider webs evolved de novo 10-14 tim...

journal_title：PeerJ

authors： Coddington JA,Agnarsson I,Hamilton CA,Bond JE

更新日期：2019-04-04 00:00:00

abstract：:Nitrogen-fixing microorganisms play important roles in N cycling. However, knowledge related to the changes in the diazotrophic community in response to cropping systems is still rudimentary. In this study, the nifH gene was used to reveal the abundance and community compositions of diazotrophs in the cropping systems...

journal_title：PeerJ

authors： Zou J,Yao Q,Liu J,Li Y,Song F,Liu X,Wang G

更新日期：2020-07-15 00:00:00