SECAPR-a bioinformatics pipeline for the rapid and user-friendly processing of targeted enriched Illumina sequences, from raw reads to alignments.

abstract：Background:Sex ratio distorting agents (maternally inherited symbionts and meiotically-driving sex chromosomes) are common in insects. When these agents rise to high frequencies they create strong population sex ratio bias and selection then favours mutations that act to restore the rare sex. Despite this strong select...

journal_title：PeerJ

authors： Reynolds LA,Hornett EA,Jiggins CD,Hurst GDD

更新日期：2019-10-01 00:00:00

abstract：:We often expect that investigations of the patterns, causes, and consequences of among-individual variation in a trait of interest will reveal how selective pressures or ecological conditions influence that trait. However, many endocrine traits, such as concentrations of glucocorticoid (GC) hormones, exhibit adaptive ...

journal_title：PeerJ

authors： Schoenemann KL,Bonier F

更新日期：2018-02-21 00:00:00

abstract：:Since 2014, Stony Coral Tissue Loss Disease (SCTLD) has led to mass mortality of the majority of hard coral species on the Florida Reef Tract. Following the successful treatment of SCTLD lesions on laboratory corals using water dosed with antibiotics, two topical pastes were developed as vehicles to directly apply ant...

journal_title：PeerJ

authors： Neely KL,Macaulay KA,Hower EK,Dobler MA

更新日期：2020-06-09 00:00:00

abstract：:Coarse-grained (CG) models have been successful in simulating the chemical properties of lipid bilayers, but accurate treatment of membrane proteins and lipid-protein molecular interactions remains a challenge. The CgProt force field, original developed with the multiscale coarse graining method, is assessed by compar...

journal_title：PeerJ

authors： Hills RD Jr

更新日期：2018-01-10 00:00:00

abstract：Background:"Quantile-dependent expressivity" occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. adiponectin) is high or low relative to its distribution. We have previously shown that the heritability (h2 ) of adiposity, lipoproteins, postprandial lipemia, pulmonary function, and ...

journal_title：PeerJ

authors： Williams PT

更新日期：2020-10-14 00:00:00

abstract：:Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mouse striatal Drd1 expression. Transduction of mouse striatum with all ...

journal_title：PeerJ

authors： Ji B,Higa K,Soontornniyomkij V,Miyanohara A,Zhou X

更新日期：2017-10-31 00:00:00

abstract：Background:Methylenetetrahydrofolate reductase (MTHFR) is indispensable for the conversion of homocysteine (Hcy) to methionine. The single nucleotide polymorphism (SNP) of MTHFR gene (rs1801133, C667T) is correlated with decreased enzyme activity that eventually results in elevated plasma Hcy levels. Hyperhomocysteinem...

journal_title：PeerJ

authors： Yuan H,Fu M,Yang X,Huang K,Ren X

更新日期：2020-02-20 00:00:00

abstract：:Haasgat is a primate-rich fossil locality in the northeastern part of the Fossil Hominid Sites of South Africa UNESCO World Heritage Site. Here we report the first hominin identified from Haasgat, a partial maxillary molar (HGT 500), that was recovered from an ex situ calcified sediment block sampled from the locality...

journal_title：PeerJ

authors： Leece AB,Kegley AD,Lacruz RS,Herries AI,Hemingway J,Kgasi L,Potze S,Adams JW

更新日期：2016-05-11 00:00:00

abstract：Background/Aims:Medical and behavioral needs are relevant in organizing and providing support strategies that improve the quality of life for children, along with their families. The present study aims to examine the impact of medical and behavioral needs on the need for support of children with disabilities. Methods:...

journal_title：PeerJ

authors： Arias VB,Aguayo V,Verdugo MA,Amor AM

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Estimating volumes and masses of total body components is important for the study and treatment monitoring of nutrition and nutrition-related disorders, cancer, joint replacement, energy-expenditure and exercise physiology. While several equations have been offered for estimating total body components from M...

journal_title：PeerJ

authors： Lacoste Jeanson A,Dupej J,Villa C,Brůžek J

更新日期：2017-05-18 00:00:00

abstract：:Physical exercise is linked to individuals whose affect profiles are invariably positive and it induces anti-apoptotic and anti-excitotoxic effects, buttressing blood-brain barrier intactness in both healthy individuals and those suffering from disorders accompanying overweight and obesity. In this regard, exercise of...

journal_title：PeerJ

authors： Garcia D,Archer T

更新日期：2014-12-16 00:00:00

abstract：:As the most widely distributed snake in Eurasia, the adder (Vipera berus) has been extensively investigated in Europe but poorly understood in Asia. The Southern Altay Mountains represent the adder's southern distribution limit in Central Asia, whereas its population status has never been assessed. We conducted, for t...

journal_title：PeerJ

authors： Cui S,Luo X,Chen D,Sun J,Chu H,Li C,Jiang Z

更新日期：2016-08-16 00:00:00

abstract：:Sanderlings (Calidris alba) are long-distance migratory shorebirds with a non-breeding range that spans temperate and tropical coastal habitats. Breeding in the High Arctic combined with non-breeding seasons in the tropics necessitate long migrations, which are energetically demanding. On an annual basis, the higher e...

journal_title：PeerJ

authors： Grond K,Ntiamoa-Baidu Y,Piersma T,Reneerkens J

更新日期：2015-08-11 00:00:00

abstract：:Exclosures that exclude large herbivores are effective tools for the protection and restoration of grazed plant communities. However, previous studies have shown that the installation of an exclosure does not ensure plant community recovery. Our study aimed to determine the effects of the domination of unpalatable pla...

journal_title：PeerJ

authors： Otsu C,Iijima H,Nagaike T

更新日期：2019-10-01 00:00:00

abstract：:Abnormalities in mitochondrial function have previously been shown in chronic fatigue syndrome (CFS) patients, implying that mitochondrial dysfunction may contribute to the pathogenesis of disease. This study builds on previous work showing that mitochondrial respiratory parameters are impaired in whole cells from CFS...

journal_title：PeerJ

authors： Tomas C,Brown AE,Newton JL,Elson JL

更新日期：2019-03-01 00:00:00

abstract：:Climatic variables have been the main predictors employed in ecological niche modeling and species distribution modeling, although biotic interactions are known to affect species' spatial distributions via mechanisms such as predation, competition, and mutualism. Biotic interactions can affect species' responses to ab...

journal_title：PeerJ

authors： Simões MVP,Peterson AT

更新日期：2018-12-05 00:00:00

abstract：:Tyrosine phosphorylation has emerged as an important regulator of plasma membrane-localized immune receptors activity. Here, we investigate the role of tyrosine phosphorylation in the regulation of rice XANTHOMONAS RESISTANCE 21 (XA21)-mediated immunity. We demonstrate that the juxtamembrane and kinase domain of Esche...

journal_title：PeerJ

authors： Caddell DF,Wei T,Sharma S,Oh MH,Park CJ,Canlas P,Huber SC,Ronald PC

更新日期：2018-12-11 00:00:00

abstract：:The goal of this study was to assess the diagnostic accuracy of acute phase proteins and proinflammatory cytokines in sheep with pneumonic pasteurellosis. Blood samples were collected from 56 sheep (36 naturally infected with Pasteurella multocida and 20 healthy controls) belonging to one farm in Eastern region, Saudi...

journal_title：PeerJ

authors： El-Deeb WM,Elmoslemany AM

更新日期：2016-07-19 00:00:00

abstract：:The genus Nothofagus is the main component of southern South American temperate forests. The 40 Nothofagus species, evergreen and deciduous, and some natural hybrids are spread among Central and Southern Chile, Argentina, New Zealand, Australia, New Guinea and New Caledonia. Nothofagus nervosa, Nothofagus obliqua and ...

journal_title：PeerJ

authors： Solano J,Anabalón L,Encina F,Esse C,Penneckamp D

更新日期：2019-05-09 00:00:00

abstract：:We present a new supertree method that enables rapid estimation of a summary tree on the scale of millions of leaves. This supertree method summarizes a collection of input phylogenies and an input taxonomy. We introduce formal goals and criteria for such a supertree to satisfy in order to transparently and justifiabl...

journal_title：PeerJ

authors： Redelings BD,Holder MT

更新日期：2017-03-01 00:00:00

abstract：:Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), which often progresses to end-stage renal disease (ESRD) and ultimately leads to death. At present, there are no definitive therapies towards LN, so that illuminating the molecular mechanism behind the disease has become an urgent ta...

journal_title：PeerJ

authors： Yang H,Li H

更新日期：2019-10-01 00:00:00

abstract：:The adaptative bleaching hypothesis (ABH) states that, depending on the symbiotic flexibility of coral hosts (i.e., the ability of corals to "switch" or "shuffle" their algal symbionts), coral bleaching can lead to a change in the composition of their associated Symbiodinium community and, thus, contribute to the cora...

journal_title：PeerJ

authors： Rouzé H,Lecellier GJ,Saulnier D,Planes S,Gueguen Y,Wirshing HH,Berteaux-Lecellier V

更新日期：2017-01-05 00:00:00

abstract：Background:The spread of maize cultivation to the highlands of central Mexico was accompanied by substantial introgression from the endemic wild teosinte Zea mays ssp. mexicana, prompting the hypothesis that the transfer of beneficial variation facilitated local adaptation. Methods:We used whole-genome sequence data t...

journal_title：PeerJ

authors： Gonzalez-Segovia E,Pérez-Limon S,Cíntora-Martínez GC,Guerrero-Zavala A,Janzen GM,Hufford MB,Ross-Ibarra J,Sawers RJH

更新日期：2019-05-03 00:00:00

abstract：:Microbes ubiquitously inhabit animals and plants, often affecting their host's phenotype. As a result, even in a constant genetic background, the host's phenotype may evolve through indirect selection on the microbiome. 'Microbiome engineering' offers a promising novel approach for attaining desired host traits but ha...

journal_title：PeerJ

authors： Arora J,Mars Brisbin MA,Mikheyev AS

更新日期：2020-07-01 00:00:00

abstract：:Xiphosurans are aquatic chelicerates with a fossil record extending into the Early Ordovician and known from a total of 88 described species, four of which are extant. Known for their apparent morphological conservatism, for which they have gained notoriety as supposed 'living fossils', recent analyses have demonstrat...

journal_title：PeerJ

authors： Lamsdell JC

更新日期：2020-12-04 00:00:00

abstract：:Hydrozoa medusae undergo blooms and seasonal fluctuations; however the drivers of such fluctuations are unknown. To understand how medusa populations fluctuate in response to seasonal factors such as temperature, salinity, dissolved oxygen, and chlorophyll a, and to enhance our taxonomic knowledge of Hydrozoa in Galve...

journal_title：PeerJ

authors： Pruski S,Miglietta MP

更新日期：2019-10-08 00:00:00

abstract：:Flatfish undergo extreme morphological development and settle to a benthic in the adult stage, and are likely to be more susceptible to environmental stress. Heat shock proteins 70 (hsp70) are involved in embryonic development and stress response in metazoan animals. However, the evolutionary history and functions of ...

journal_title：PeerJ

authors： Liu K,Hao X,Wang Q,Hou J,Lai X,Dong Z,Shao C

更新日期：2019-11-11 00:00:00

abstract：:Background. Pollinators, which provide the agriculturally and ecologically essential service of pollination, are under threat at a global scale. Habitat loss and homogenisation, pesticides, parasites and pathogens, invasive species, and climate change have been identified as past and current threats to pollinators. Ac...

journal_title：PeerJ

authors： Brown MJ,Dicks LV,Paxton RJ,Baldock KC,Barron AB,Chauzat MP,Freitas BM,Goulson D,Jepsen S,Kremen C,Li J,Neumann P,Pattemore DE,Potts SG,Schweiger O,Seymour CL,Stout JC

更新日期：2016-08-09 00:00:00

abstract：:The MYB transcription factor family is one of the largest gene families playing regulatory roles in plant growth and development. The MYB family has been studied in a variety of plant species but has not been reported in Taxus chinensis. Here we identified 72 putative R2R3-MYB genes in T. chinensis using a comprehensi...

journal_title：PeerJ

authors： Hu X,Zhang L,Wilson I,Shao F,Qiu D

更新日期：2020-02-17 00:00:00

abstract：:There is a lack of stability in language difficulties across early childhood: most late talkers (LTs) resolve their difficulties by pre-school; and a significant number of children who were not LTs subsequently manifest language difficulties. Greater reliability in predicting individual outcomes is needed, which might...

journal_title：PeerJ

authors： Duff FJ,Nation K,Plunkett K,Bishop D

更新日期：2015-07-23 00:00:00