A novel animal model for neuroinflammation and white matter degeneration.

abstract：Purpose:Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods:A retrospective, single-center case series study of 275 NBs was implem...

journal_title：PeerJ

authors： Ma Y,Zheng J,Feng J,Chen L,Dong K,Xiao X

更新日期：2018-09-17 00:00:00

abstract：:Late positive event-related potential (ERP) components occurring after the N400, traditionally linked to reanalysis due to syntactic incongruence, are increasingly considered to also reflect reanalysis and repair due to semantic difficulty. Semantic problems can have different origins, such as a mismatch of specific p...

journal_title：PeerJ

authors： Quante L,Bölte J,Zwitserlood P

更新日期：2018-10-12 00:00:00

abstract：BACKGROUND:In previous studies, both 17β-estradiol (E2) and resveratrol (RES) were reported to protect intervertebral disc cells against aberrant apoptosis. Given that E2 has a better anti-apoptotic effect with more cancer risk and RES has an anti-apoptotic effect with less cancer risk, the combined use of E2 with RES ...

journal_title：PeerJ

authors： Yang SD,Ma L,Yang DL,Ding WY

更新日期：2016-01-26 00:00:00

abstract：Introduction:Whole-metagenome sequencing can be a rich source of information about the structure and function of entire metagenomic communities, but getting accurate and reliable results from these datasets can be challenging. Analysis of these datasets is founded on the mapping of sequencing reads onto known genomic r...

journal_title：PeerJ

authors： Greenfield P,Tran-Dinh N,Midgley D

更新日期：2019-01-30 00:00:00

abstract：Background:Mimusops coriacea (A.DC.) Miq., (Sapotaceae), originated from Africa, were introduced to coastal areas in Ecuador where it is not extensively used as a traditional medicine to treat various human diseases. Different therapeutically uses of the species include: analgesic, antimicrobial, hypoglycemic, inflamma...

journal_title：PeerJ

authors： Bustamante K,Santos-Ordóñez E,Miranda M,Pacheco R,Gutiérrez Y,Scull R

更新日期：2019-10-11 00:00:00

abstract：:White-handed gibbons produce loud and acoustically complex songs when interacting with their neighbours or when encountering predators. In both contexts, songs are assembled from a small number of units although their composition differs in context-specific ways. Here, we investigated whether wild gibbons could infer ...

journal_title：PeerJ

authors： Andrieu J,Penny SG,Bouchet H,Malaivijitnond S,Reichard UH,Zuberbühler K

更新日期：2020-08-03 00:00:00

abstract：AIMS:Mountain ranges in the tropics are characterised by high levels of localised endemism, often-aberrant evolutionary trajectories, and some of the world's most diverse regional biotas. Here we investigate the evolution of montane endemism, ecology and body size in a clade of direct-developing frogs (Choerophryne, Mi...

journal_title：PeerJ

authors： Oliver PM,Iannella A,Richards SJ,Lee MS

更新日期：2017-03-30 00:00:00

abstract：:The study of vertebrate ontogenies has the potential to inform us of shared developmental patterns and processes among organisms. However, fossilised ontogenies of early vertebrates are extremely rare during the Palaeozoic Era. A growth series of the Late Devonian "acanthodian" Triazeugacanthus affinis, from the Migua...

journal_title：PeerJ

authors： Chevrinais M,Sire JY,Cloutier R

更新日期：2017-10-27 00:00:00

abstract：:We present a new supertree method that enables rapid estimation of a summary tree on the scale of millions of leaves. This supertree method summarizes a collection of input phylogenies and an input taxonomy. We introduce formal goals and criteria for such a supertree to satisfy in order to transparently and justifiabl...

journal_title：PeerJ

authors： Redelings BD,Holder MT

更新日期：2017-03-01 00:00:00

abstract：:The culture of pelagic marine invertebrates, especially the ctenophore Mnemiopsis leidyi, has been demonstrated in past studies dating back to the 1960s; however, the mass culture of delicate pelagic invertebrates has remained elusive. By using a pair of acrylic tubes and enabling water diffusion between them, we have...

journal_title：PeerJ

authors： Patry WL,Bubel M,Hansen C,Knowles T

更新日期：2020-04-07 00:00:00

abstract：:Vitellogenin has been proposed to regulate division of labor and social organization in social insects. The red imported fire ant (Solenopsis invicta) harbors four distinct, adjacent vitellogenin genes (Vg1, Vg2, Vg3, and Vg4). Contrary to honey bees that have a single Vg ortholog as well as potentially fertile nurses...

journal_title：PeerJ

authors： Hawkings C,Tamborindeguy C

更新日期：2018-05-28 00:00:00

abstract：:Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims of this study were to determine the prevalence of the combined morbidity of DM & hypothyroidism and whether...

journal_title：PeerJ

authors： Tirosh D,Benshalom-Tirosh N,Novack L,Press F,Beer-Weisel R,Wiznitzer A,Mazor M,Erez O

更新日期：2013-03-19 00:00:00

abstract：:Background. Although the trot is described as a diagonal gait, contacts of the diagonal pairs of hooves are not usually perfectly synchronized. Although subtle, the timing dissociation between contacts of each diagonal pair could have consequences on gait dynamics and provide insight into the functional strategies emp...

journal_title：PeerJ

authors： Hobbs SJ,Bertram JE,Clayton HM

更新日期：2016-06-30 00:00:00

abstract：Background:Extensive genome rearrangements, known as chromothripsis, have been recently identified in several cancer types. Chromothripsis leads to complex structural variants (cSVs) causing aberrant gene expression and the formation of de novo fusion genes, which can trigger cancer development, or worsen its clinical ...

journal_title：PeerJ

authors： Hynst J,Plevova K,Radova L,Bystry V,Pal K,Pospisilova S

更新日期：2019-06-12 00:00:00

abstract：Background:The table tennis serve involves complex spatial movements combined with biomechanial characteristics. Although the differences in lower-limb biomechanial characteristics to a great extent influence the translational and spinning velocity of the ball when using the different styles of table tennis serve, few ...

journal_title：PeerJ

authors： Yu C,Shao S,Baker JS,Gu Y

更新日期：2018-06-01 00:00:00

abstract：:Due to its remote and isolated location, Antarctica is home to a unique diversity of species. The harsh conditions have shaped a primarily highly adapted endemic fauna. This includes the notothenioid family Channichthyidae. Their exceptional physiological adaptations have made this family of icefish the focus of many ...

journal_title：PeerJ

authors： Kuhn T,Zizka VMA,Münster J,Klapper R,Mattiucci S,Kochmann J,Klimpel S

更新日期：2018-05-11 00:00:00

abstract：:Banana streak virus (BSV) belongs to the members of the genus Badnavirus, family Caulimoviridae. At present, BSV contains nine species in the International Committee on Taxonomy of Viruses (ICTV) classification report (2018b release). Previous study indicated that the viral particles of Banana streak virus Acuminata Y...

journal_title：PeerJ

authors： Li WL,Yu NT,Wang JH,Li JC,Liu ZX

更新日期：2020-01-27 00:00:00

abstract：Background:This systematic review aimed to investigate the psychometric properties of the school health's assessment tools in primary schools through COSMIN Risk of Bias checklist. We examined the studies that have addressed the measurement properties of school-health instruments to give a clear overview of the quality...

journal_title：PeerJ

authors： Kazemitabar M,Moghadamzadeh A,Habibi M,Hakimzadeh R,Garcia D

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. METHODS:TEM, SEM and ATP efflux ...

journal_title：PeerJ

authors： Jindal HM,Zandi K,Ong KC,Velayuthan RD,Rasid SM,Samudi Raju C,Sekaran SD

更新日期：2017-10-05 00:00:00

abstract：:Evolutionary biology has entered an era of unprecedented amounts of DNA sequence data, as new sequencing technologies such as Massive Parallel Sequencing (MPS) can generate billions of nucleotides within less than a day. The current bottleneck is how to efficiently handle, process, and analyze such large amounts of da...

journal_title：PeerJ

authors： Andermann T,Cano Á,Zizka A,Bacon C,Antonelli A

更新日期：2018-07-13 00:00:00

abstract：:The coevolutionary relationships between brood parasites and their hosts are often studied by examining the egg rejection behaviour of host species using artificial eggs. However, the traditional methods for producing artificial eggs out of plasticine, plastic, wood, or plaster-of-Paris are laborious, imprecise, and p...

journal_title：PeerJ

authors： Igic B,Nunez V,Voss HU,Croston R,Aidala Z,López AV,Van Tatenhove A,Holford ME,Shawkey MD,Hauber ME

更新日期：2015-05-26 00:00:00

abstract：:Seymouria is the best known of the seymouriamorphs, a group of Permo-Carboniferous reptiliomorphs with both terrestrial and aquatic taxa. The majority of research on Seymouria has focused on cranial anatomy, with few detailed descriptions or illustrations of the postcrania. We utilized neutron computed tomography (nCT...

journal_title：PeerJ

authors： Bazzana KD,Gee BM,Bevitt JJ,Reisz RR

更新日期：2020-03-10 00:00:00

abstract：Background:Little is known regarding the toxic and therapeutic doses of amygdalin. Treatment regimens and schedules can vary between humans and animal models, and there have been reports of cyanide toxicity due to amygdalin use. Objective:The aim of this study was to evaluate the effect of different doses of amygdalin...

journal_title：PeerJ

authors： Albogami S,Hassan A,Ahmed N,Alnefaie A,Alattas A,Alquthami L,Alharbi A

更新日期：2020-05-21 00:00:00

abstract：:Divergences between agricultural management can result in different types of biological interactions between plants and microorganisms, which may affect food quality and productivity. Conventional practices are well-established in the agroindustry as very efficient and lucrative; however, the increasing demand for sus...

journal_title：PeerJ

authors： Carvalho CR,Dias AC,Homma SK,Cardoso EJ

更新日期：2020-06-02 00:00:00

abstract：:Nephila clavata L Koch, known as the Joro spider and native to East Asia (Japan, China, Korea, and Taiwan), is newly reported from North America. Specimens from several locations in northeast Georgia were collected from around residential properties in Barrow, Jackson, and Madison counties in late October and early No...

journal_title：PeerJ

authors： Hoebeke ER,Huffmaster W,Freeman BJ

更新日期：2015-02-05 00:00:00

abstract：:Histone deacetylases (HDACs) are key epigenetic factors in regulating chromatin structure and gene expression in multiple aspects of plant growth, development, and response to abiotic or biotic stresses. Many studies on systematic analysis and molecular function of HDACs in Arabidopsis and rice have been conducted. Ho...

journal_title：PeerJ

authors： Zhang K,Yu L,Pang X,Cao H,Si H,Zang J,Xing J,Dong J

更新日期：2020-02-12 00:00:00

abstract：:Root hairs are unicellular elongations of certain rhizodermal cells that improve the uptake of sparingly soluble and immobile soil nutrients. Among different Arabidopsis thaliana genotypes, root hair density, length and the local acclimation to low inorganic phosphate (Pi) differs considerably, when analyzed on split ...

journal_title：PeerJ

authors： Stetter MG,Benz M,Ludewig U

更新日期：2017-01-24 00:00:00

abstract：Background:Stellera chamaejasme Linn, an important poisonous plant of the China grassland, is toxic to humans and livestock. The rapid expansion of S. chamaejasme has greatly damaged the grassland ecology and, consequently, seriously endangered the development of animal husbandry. To draft efficient prevention and cont...

journal_title：PeerJ

authors： Liu X,Guan H,Song M,Fu Y,Han X,Lei M,Ren J,Guo B,He W,Wei Y

更新日期：2018-04-03 00:00:00

abstract：:Ocean acidification (OA) is not an isolated threat, but acts in concert with other impacts on ecosystems and species. Coastal marine invertebrates will have to face the synergistic interactions of OA with other global and local stressors. One local factor, common in coastal environments, is trace element contamination...

journal_title：PeerJ

authors： Horwitz R,Borell EM,Fine M,Shaked Y

更新日期：2014-09-09 00:00:00

abstract：:The ε subunit from ATP synthases acts as an ATP sensor in the bacterial cell to prevent ATP hydrolysis and thus the waste of ATP under conditions of low ATP concentration. However, the ATP binding affinities from various bacterial organisms differ markedly, over several orders of magnitude. For example, the ATP syntha...

journal_title：PeerJ

authors： Krah A,Bond PJ

更新日期：2018-09-05 00:00:00