Sunao Tawara : further musings on his tribulations in providing the basis for the modern-day understanding of cardiac electrophysiology.

Abstract:

:Sunao Tawara, who was born in 1873 and died in 1952, is considered the father of modern cardiac electrophysiology. He published his monumental monograph describing the atrioventricular conduction axis in 1906. He achieved this task in the face of multiple tribulations as a doctoral student working in a cultural environment that was not his own. Although his letters underscoring the publication of the monograph have been published, little emphasis has been placed on the potential problems he encountered in bringing his task to fruition. For example, it was not until the final 6 months of his studies that he resolved the issue of the connection between the atrioventricular bundle and the so called "Purkinje cardiomyocytes". His exchanges with his mentor, Ludwig Aschoff, emphasized that the difficulties he encountered in making the connection caused him quite some turmoil. We believe that this issue, and others that he identified in his correspondence, are worthy of further attention.

journal_name

Anat Sci Int

authors

De Almeida MC,Sanchez-Quintana D,Anderson RH

doi

10.1007/s12565-020-00530-6

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

381-386

issue

3

eissn

1447-6959

issn

1447-073X

pii

10.1007/s12565-020-00530-6

journal_volume

95

pub_type

传,历史文章,杂志文章
  • A multitude of variations in the configuration of the circle of Willis: an autopsy study.

    abstract::The circle of Willis (CW) is an anastomotic system of arteries located at the base of the brain. The aim of the study was to evaluate the anatomic configuration of the CW in the Polish population and to compare results with previously conducted research. Brains were obtained from 100 recently deceased human adults, an...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-015-0301-2

    authors: Klimek-Piotrowska W,Rybicka M,Wojnarska A,Wójtowicz A,Koziej M,Hołda MK

    更新日期:2016-09-01 00:00:00

  • Visualization of spatiotemporal differentiation of dopaminergic interneurons in adult mouse olfactory bulb using transgenic mice.

    abstract::Olfactory bulb (OB) interneurons, predominantly periglomerular (PG) and granule (GR) cells, are derived from neural stem cells in the subventricular zone (SVZ) throughout life and migrate to the OB in the rostral migratory stream (RMS). In the adult superficial GR layer transgene expression was found, either enhanced ...

    journal_title:Anatomical science international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1447-073X.2007.00209.x

    authors: Saino-Saito S

    更新日期:2008-12-01 00:00:00

  • Topographical relationship between the accessory hepatic duct and the hepatic artery system.

    abstract::Hepatic biliary injury is one of the most common complications in cholecystectomy and is frequently accompanied by arterial injuries. Because there are several anatomical variations of the hepatic ducts, including the accessory hepatic ducts (AHDs), it is important to consider not only the anatomical position of the h...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-020-00568-6

    authors: Tanaka T,Nakada T,Ito T,Kominami R,Sonomura T,Kagaya M,Kawai K,Honma S

    更新日期:2021-01-01 00:00:00

  • Histological investigation of rabbit ligamentum flavum with special reference to differences in spinal levels.

    abstract::The structure of the ligamentum flavum has yet to be fully elucidated and no studies have investigated fine structural differences at different spinal levels in any animals. The aim of the present study was to clarify structural differences in the ligamentum flavum at different spinal levels (cervical: C3/4 and C5/6; ...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1046/j.0022-7722.2003.00050.x

    authors: Nihei A,Hagiwara K,Kikuchi M,Yashiro T,Hoshino Y

    更新日期:2003-09-01 00:00:00

  • The effects of soy and tamoxifen on apoptosis in the hippocampus and dentate gyrus in a pentylenetetrazole-induced seizure model of ovariectomized rats.

    abstract::The effects of tamoxifen and soy on apoptosis of the hippocampus and dentate gyrus of ovariectomized rats after repeated seizures were investigated. Female rats were divided into: (1) Control, (2) Sham, (3) Sham-Tamoxifen (Sham-T), (4) Ovariectomized (OVX), (5) OVX-Tamoxifen (OVX-T), (6)OVX-Soy(OVX-S) and (7) OVX-S-T....

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-017-0398-6

    authors: Ebrahimzadeh-Bideskan AR,Mansouri S,Ataei ML,Jahanshahi M,Hosseini M

    更新日期:2018-03-01 00:00:00

  • Temporal changes in testis weight during the past 50 years in Japan.

    abstract::The ever-increasing presence of environmental toxicants and their disruptive effect on the reproductive systems of wildlife raises the question of possible damage to the human reproductive system. Using medicolegal data from over 20,000 Japanese men subjected to necropsy from 1948 to 1998, we investigated temporal cha...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1046/j.0022-7722.2002.00009.x

    authors: Mori C,Hamamatsu A,Fukata H,Koh KB,Nakamura N,Takeichi S,Kusakabe T,Saito T,Morita M,Tanihara S,Kayama F,Shiyomi M,Yoshimura J,Sagisaka K

    更新日期:2002-06-01 00:00:00

  • Identification and functional analysis of damage-induced neuronal endopeptidase (DINE), a nerve injury associated molecule.

    abstract::Nerve regeneration is a complex process associated with the expression of hundreds of genes. To elucidate the molecular mechanism responsible for nerve regeneration, hundreds of nerve regeneration-associated genes have been hunted using differential display polymerase chain reaction (DD-PCR), random cloning, microarra...

    journal_title:Anatomical science international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1447-073X.2006.00136.x

    authors: Kiryu-Seo S

    更新日期:2006-03-01 00:00:00

  • Iulius Casserius: revolutionary anatomist, teacher and pioneer of the sixteenth and seventeenth century.

    abstract::The demand for anatomical illustrations in the early modern period coincided with a scientific revolution. Starting out as a servant, Iulius Casserius became a great anatomist, who challenged the Galenic doctrine. The aim of this paper is to honor his memory and recreate the stylism of his anatomical illustrations. On...

    journal_title:Anatomical science international

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/s12565-016-0326-1

    authors: Wysocki M,Saganiak K,Zwinczewska H,Roy J,Tomaszewski KA,Walocha JA

    更新日期:2016-06-01 00:00:00

  • Histological study in the brain of the reelin/Dab1-compound mutant mouse.

    abstract::The Reelin (Reln)-deficient mouse (reeler) and the Dab1-deficient mouse (yotari) are autosomal recessive mutant mice characterized by cerebellar ataxia. Previously, we reported that Reelin and Dab1 proteins have slightly different functions during the development of the cerebral cortex. To analyze the functional roles...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-008-0009-7

    authors: Yamamoto T,Setsu T,Okuyama-Yamamoto A,Terashima T

    更新日期:2009-09-01 00:00:00

  • Plastic casts and confocal laser scanning microscopy applied to the observation of enamel tubules in the red Kangaroo (Macropus rufus).

    abstract::Scanning electron microscopy for plastic casts and confocal laser scanning microscopy for Villanueva bone-stained ground sections were used together to observe enamel tubules in red kangaroo molars. Although the tubular structures such as terminals, bends, expansions, splits, divergences and rejoinings in this species...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1046/j.0022-7722.2003.00039.x

    authors: Suzuki M,Ushijima N,Kohno A,Sawa Y,Yoshida S,Sekikawa M,Ohtaishi N

    更新日期:2003-03-01 00:00:00

  • Location and morphometry of the thyroid isthmus in adult Korean cadavers.

    abstract::The thyroid isthmus has different measurements in its width, height, and thickness, and its location with respect to the tracheal rings has been inconsistent, among the anatomical literature. This study was performed to clarify the location and morphometric characteristics of the thyroid isthmus. One hundred thyroid i...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-013-0187-9

    authors: Won HS,Han SH,Oh CS,Chung IH,Won HJ,Kim JH

    更新日期:2013-09-01 00:00:00

  • A case of right partial and double internal jugular veins.

    abstract::We present a very rare case of right partial and double internal jugular veins, found in an 86-year-old Japanese female cadaver during a student dissection practice session in 2002 at Osaka Dental University. In this case, the right internal jugular vein separated into medial and lateral branches at a level with the m...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1111/j.1447-073X.2006.00119.x

    authors: Uemura M,Takemura A,Tamada Y,Toda I,Ike H,Suwa F

    更新日期:2006-03-01 00:00:00

  • The "polymorphous" history of a polymorphous skull bone: the sphenoid.

    abstract::For a long time, because of its location at the skull base level, the sphenoid bone was rather mysterious as it was too difficult for anatomists to reach and to elucidate its true configuration. The configuration of the sphenoid bone led to confusion regarding its sutures with the other skull bones, its shape, its det...

    journal_title:Anatomical science international

    pub_type: 杂志文章,评审

    doi:10.1007/s12565-017-0399-5

    authors: Costea C,Turliuc S,Cucu A,Dumitrescu G,Carauleanu A,Buzduga C,Sava A,Costache I,Turliuc D

    更新日期:2018-01-01 00:00:00

  • Prenatal stress induces learning deficits and is associated with a decrease in granules and CA3 cell dendritic tree size in rat hippocampus.

    abstract::Exposure to gestational stress impairs hippocampal-dependent learning in offspring. In spite of the known decisive role of hippocampal dendritic architecture in learning and memory, there has been no study to date that examines the effect of prenatal stress on the morphology of the hippocampal neurons. Therefore we pe...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1111/j.1447-073X.2007.00186.x

    authors: Hosseini-Sharifabad M,Hadinedoushan H

    更新日期:2007-12-01 00:00:00

  • Anatomical study of partial anomalous pulmonary venous return with special references to the bronchial vein: supplementary report.

    abstract::After the authors' previous report an additional case of partial anomalous pulmonary venous return was encountered during dissection practice for medical students. In an 87-year-old Japanese male cadaver, the anomalous vein from the right upper lobe drained into the superior vena cava at a point just below the entranc...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1111/j.1447-073X.2007.00187.x

    authors: Okamoto K,Wakebe T,Saiki K

    更新日期:2008-09-01 00:00:00

  • Neuroprotective effect of regular swimming exercise on calretinin-positive striatal neurons of Parkinsonian rats.

    abstract::In Parkinson's disease (PD), physical therapy is one of the mainstays of supportive treatment modalities. This study focused on the neuroprotective effect of regular exercise on striatal calretinin positive interneurons in a rat model of PD. 6-hydroxydopamine (6-OHDA) was injected unilaterally into the medial forebrai...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-020-00538-y

    authors: Boracı H,Kirazlı Ö,Gülhan R,Yıldız Sercan D,Şehirli ÜS

    更新日期:2020-09-01 00:00:00

  • Anatomical review of the lateral collateral ligaments of the ankle: a cadaveric study.

    abstract::Arrangements of the lateral collateral ligaments of the ankle are complex. Injuries to these ligaments can occur in the inverted planter flexed position of the ankle. Traditionally, the anterior talofibular ligament (ATFL) is the first ligament involved in such ankle injuries. We reviewed the anatomical arrangements o...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-011-0109-7

    authors: Raheem OA,O'Brien M

    更新日期:2011-12-01 00:00:00

  • Effects of different cadaver preservation methods on muscles and tendons: a morphometric, biomechanical and histological study.

    abstract::No prior publication studying the biomechanical and histological properties of cadavers fixed with Logan or modified Logan solution (MLS) was found in the literature. It was aimed in this study to compare MLS fixation and other cadaver preservation procedures regarding the use in basic histological studies, anatomy ed...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-019-00508-z

    authors: Beger O,Karagül Mİ,Koç T,Kayan G,Cengiz A,Yılmaz ŞN,Olgunus ZK

    更新日期:2020-03-01 00:00:00

  • The anatomy of the sacrococcygeal cornual region and its clinical relevance.

    abstract::There has been no systematic study of the anatomy of the region between the sacral and coccygeal cornua. Reference texts describe an intercornual ligament connecting these structures. The aim of this study was to investigate the anatomy of this region, which may be relevant to unexplained cases of coccygeal pain (cocc...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-013-0222-x

    authors: Woon JT,Stringer MD

    更新日期:2014-09-01 00:00:00

  • Morphological study of the northern pike (Esox lucius) tongue.

    abstract::The northern pike (Esox lucius) is a fresh water species belonging to the Esocidae family. It is a carnivorous fish feeding mostly on invertebrates and fishes. Due to the scantiness of relevant literature regarding the morphology of the tongue in fish we carried out this study with the aim of providing information on ...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-014-0254-x

    authors: Sadeghinezhad J,Rahmati-holasoo H,Fayyaz S,Zargar A

    更新日期:2015-09-01 00:00:00

  • The possibilities of studying human embryos and foetuses using micro-CT: a technical note.

    abstract::The purpose of the study was to discover a way to study the internal structure and evolution of human embryos noninvasively. The human embryo was stained with phosphotungstic acid solution (PTA) in ethanol (EPTA) and scanned using a micro computed tomography (micro-CT) scanner. Using appropriate software, a three-dime...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-016-0377-3

    authors: Vymazalová K,Vargová L,Zikmund T,Kaiser J

    更新日期:2017-03-01 00:00:00

  • Implications for thymus growth in childhood: histogenesis of cortex and medulla.

    abstract::The increase in autoimmune diseases in recent years has drawn attention back to the thymus, with new approaches to improve and/or restore immune function being investigated. As the primary lymphoid organ responsible for functional T cell development, studies on the pre-/post-natal development of this organ and T lymph...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-018-0456-8

    authors: Ayran Fidan P,Kaymaz FF,Dagdeviren A

    更新日期:2019-01-01 00:00:00

  • Persistent median artery in the hand: a report with a brief review of the literature.

    abstract::We encountered a persistent median artery in the forearms and hands bilaterally in a 78-year-old Japanese male cadaver during dissection practice at Wakayama Medical University. The brachial arteries divided into the ulnar and radial arteries. The ulnar artery gave off the median and posterior interosseous arteries at...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1111/j.1447-073X.2006.00150.x

    authors: Tsuruo Y,Ueyama T,Ito T,Nanjo S,Gyoubu H,Satoh K,Iida Y,Nakai S

    更新日期:2006-12-01 00:00:00

  • The superficial brachial artery passing superficially to the pectoral ansa, the highest superficial brachial artery (Arteria brachialis superficialis suprema).

    abstract::The human superficial brachial artery passes superficially to the median nerve and can be classified into three subtypes according to its topographical relationship to the pectoral ansa. When the superficial brachial artery passes superficially to the pectoral ansa, it is defined as the highest superficial artery. We ...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-010-0094-2

    authors: Honma S,Kawai K,Koizumi M,Kodama K

    更新日期:2011-06-01 00:00:00

  • Brain ventricle development in H. huso (Beluga sturgeon) larvae.

    abstract::The development of ventricles in the brain of H. huso (Beluga sturgeon) from 1 to 54 days old is presented in this study. The components observed in the 1-day-old ventricular system were the telencephalic, tectal, and cerebellar ventricles. These ventricles were not observed to have any recess or sulcus. They were sur...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-015-0307-9

    authors: Tavighi SH,Saadatfar Z,Shojaei B,Rassouli MB

    更新日期:2016-09-01 00:00:00

  • Persistent hypoglossal artery with hypoplasia of the vertebral and posterior communicating arteries.

    abstract::We observed a rare case of the right persistent hypoglossal artery (PHA) in the posterior cranial fossa of a deceased 74-year-old Japanese man who did not have any clinical manifestations related to this anomaly when alive. The large-sized PHA originating from the cervical internal carotid artery passed through the hy...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-009-0062-x

    authors: Terayama R,Toyokuni Y,Nakagawa S,Nakatsuji K,Nakama H,Yamaai T,Ichikawa H,Sugimoto T

    更新日期:2011-03-01 00:00:00

  • Role of the CXCL12/CXCR4 axis in milky spots of rats bearing ascitic-type hepatoma.

    abstract::Rat ascitic-type hepatoma AH7974 cells express CXCR4 mRNA and protein at high levels and also show vigorous migratory responses to its ligand CXCL12. We have shown that AMD3100 (a specific CXCR4 antagonist) effectively reduced tumor invasion into the milky spot in Sprague-Dawley rats inoculated with AH7974 cells. A hi...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-009-0028-z

    authors: Abe H,Ina K,Kitamura H,Sumiyoshi H,Tatsukawa S,Yoshioka H,Fujikura Y

    更新日期:2009-09-01 00:00:00

  • Chondroepitrochlearis and a supernumerary head of the biceps brachii.

    abstract::Unique variants of the pectoralis major and biceps brachii were found during a routine student dissection of a 96-year-old Caucasian female's axilla and brachium. The donor cadaver had bilateral presentation of a muscle originating from the pectoralis major, near the lateral lip of the intertubercular groove, extendin...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1007/s12565-019-00483-5

    authors: Carroll MA,Lebron EM,Jensen TE,Cooperman TJ

    更新日期:2019-09-01 00:00:00

  • Colchicine-induced apoptosis and anti-Fas localization in rat-incisor ameloblasts.

    abstract::Apoptosis of ameloblasts were examined by the TdT-mediated dUTP-biotin nick end-labelling method and electron microscopy 8 h after injection of colchicine. The results showed that extensive apoptosis occurred in ameloblasts of secretion to maturation zones. To determine the possible involvement of stimulators in amelo...

    journal_title:Anatomical science international

    pub_type: 杂志文章

    doi:10.1046/j.0022-7722.2002.00025.x

    authors: Nishikawa S

    更新日期:2002-09-01 00:00:00

  • Regulation of neural development by glial cell line-derived neurotrophic factor family ligands.

    abstract::Glial cell line-derived neurotrophic factor (GDNF) and its three relatives constitute a novel family of neurotrophic factors, the GDNF family ligands. These factors signal through a multicomponent receptor complex comprising a glycosylphosphatidylinositol-anchored cell surface molecule (GDNF family receptor (GFR) alph...

    journal_title:Anatomical science international

    pub_type: 杂志文章,评审

    doi:10.1111/j.1447-073x.2005.00099.x

    authors: Enomoto H

    更新日期:2005-03-01 00:00:00