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Pathology definitions and resection strategies for early colorectal neoplasia: Eastern versus Western approaches in the post-Vienna era.

Abstract：

:There is a well-known discrepancy between East and West classifications of colorectal neoplasm, especially "intramucosal carcinoma," categorized as subgroup 4.4 in the Vienna classification, usually recognized as high-grade dysplasia in the United States and as carcinoma in situ in Japan. Focusing on management, in the current National Comprehensive Cancer Network algorithm, high-grade dysplasia, carcinoma in situ, and intramucosal carcinoma are managed similarly, whereas submucosal invasion by carcinoma requires en bloc resection. To bridge the differences with regard to these conceptual problems in the definition and management of carcinoma in situ and intramucosal carcinoma, endoscopists and pathologists from Japan and the United States gathered and discussed from their perspectives how to accurately assess specimens of en bloc/piecemeal resection and to effectively predict lymph node metastasis risk.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Nishimura M,Saito Y,Nakanishi Y,Shia J,Lauwers GY,Wallace MB

doi

10.1016/j.gie.2019.12.021

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

983-988

issue

5

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(19)32563-5

journal_volume

91

pub_type

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