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Acute extraluminal hemorrhage associated with EUS-guided fine needle aspiration: frequency and clinical significance.

Abstract：

BACKGROUND:Complications with EUS-guided fine needle aspiration cytology (EUS-guided FNA) are rare and include perforation, infection, pancreatitis, and intraluminal bleeding. To date, the ultrasound appearance and clinical significance of perilesional bleeding during EUS-guided FNA have not been described. The aim of this study was to analyze the frequency of acute extraluminal hemorrhage associated with EUS-guided FNA. METHODS:From September 1998 to October 1999 EUS-guided FNA was performed during 227 of 1104 EUS procedures. Patient follow-up and complications were recorded and retrospectively analyzed. OBSERVATIONS:Three patients were identified with acute extraluminal hemorrhage at the site of the aspiration during EUS (frequency 1.3%: 95% CI [0%, 2.8%]). The bleeding manifested as an expanding echopoor region adjacent to the sampled lesion. No clinically recognizable sequela arose from the bleeding. All patients were treated with a short course of antibiotics and outpatient observation. Preprocedure coagulation and platelet assessment did not predict which patients were at risk for this complication. CONCLUSION:Acute extraluminal hemorrhage occurring during EUS-guided FNA is a rare complication with a characteristic ultrasound appearance. Recognition of this event might be important to allow the endoscopist to terminate the procedure and thereby minimize the potential for more serious bleeding.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Affi A,Vazquez-Sequeiros E,Norton ID,Clain JE,Wiersema MJ

doi

10.1067/mge.2001.111391

keywords:

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

221-5

issue

2

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(01)70372-0

journal_volume

53

pub_type

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