Abstract:
BACKGROUND:The importance of sedation during endoscopy is well established. There is no consensus about the best techniques for sedation, which specialist should perform it, and in which location. OBJECTIVE:To provide data on the epidemiology of adverse events during sedation for endoscopy. DESIGN:Retrospective analysis of a prospective database. SETTING:Endoscopy unit of a university hospital. PROCEDURES:A total of 17,999 procedures performed over 8 years. INTERVENTIONS:Sedation for GI endoscopy. MAIN OUTCOME MEASUREMENTS:We recorded the following information: sex, age, body mass index, smoking habits, American Society of Anesthesiologists and Mallampati scores, duration of the procedure, type of sedative drug administered, whether the procedure was performed emergently, and endoscopic interventions during the maneuver. Adverse events were defined as occurrences that warranted intervention and were classified as hypotension, desaturation, bradycardia, hypertension, arrhythmia, aspiration, respiratory depression, vomiting, cardiac arrest, respiratory arrest, angina, hypoglycemia, and/or allergic reaction. RESULTS:Deep sedation with intravenous propofol target controlled infusion pump was the most frequently used means of administering sedation. Adverse events were rare in both the adult (4.5%) and pediatric (2.6%) populations. Six complications occurred in more than 0.1% of adult cases: arterial hypotension, desaturation, bradycardia, arterial hypertension, arrhythmia, and aspiration. Only bradycardia (2.1%) and hypotension (0.44%) occurred in children. Three adult patients (0.017%) died, and no pediatric patients died. Some predictive models for the occurrence of complications are proposed. LIMITATIONS:Retrospective analysis, single-center data collection. CONCLUSIONS:Deep sedation during endoscopic procedures is safe in both adults and children. Our data may be useful for the future planning of new clinical strategies in this setting.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Agostoni M,Fanti L,Gemma M,Pasculli N,Beretta L,Testoni PAdoi
10.1016/j.gie.2011.04.028subject
Has Abstractpub_date
2011-08-01 00:00:00pages
266-75issue
2eissn
0016-5107issn
1097-6779pii
S0016-5107(11)01637-3journal_volume
74pub_type
杂志文章abstract:BACKGROUND:Self-expandable metal stents (SEMSs) are an established palliative therapy for esophageal cancer. SEMS placement for cancers near the upper esophageal sphincter (UES) is controversial because of a perceived increased risk of complications. OBJECTIVE:To compare outcomes after patients stented for proximal es...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.gie.2010.11.036
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Permanent dysphagia occurring after laryngectomy or laryngopharyngectomy can usually be treated by periodic dilation. Occasionally, however, conservative treatment is insufficient, and patients require long-term tube feeding. We describe 4 cases with stricture after laryngopharyngectomy who underwent inserti...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2009.12.050
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Complications with EUS-guided fine needle aspiration cytology (EUS-guided FNA) are rare and include perforation, infection, pancreatitis, and intraluminal bleeding. To date, the ultrasound appearance and clinical significance of perilesional bleeding during EUS-guided FNA have not been described. The aim of ...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2001.111391
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:The most important aspect of the surgical management of Zenker's diverticulum is probably the cricopharyngeal myotomy. Endoscopic diverticulotomy can be performed with a needle-knife papillotome, which allows simultaneous myotomy of the upper esophageal sphincter. METHODS:Since 1978, 47 patients (28 men and...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(99)70452-9
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Autoimmune pancreatitis has been proposed as a new clinical entity. However, the ERCP features of this entity have not been well described. METHODS:Clinical and radiographic features in 27 patients with a diagnosis of autoimmune pancreatitis were evaluated. RESULTS:All 27 patients were at first suspected t...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2002.122653
更新日期:2002-04-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2006.12.042
更新日期:2007-07-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(03)02010-8
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND AND AIMS:Hepatic venous pressure gradient (HVPG) currently serves as a surrogate for portal pressure measurement but has many limitations. We developed a novel technique for rapid and direct portal pressure measurements using a digital pressure wire delivered through an EUS-guided 22-gauge FNA needle. Our ai...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2015.11.038
更新日期:2016-04-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
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更新日期:2001-07-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
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更新日期:1998-08-01 00:00:00
abstract:BACKGROUND:When choledochoscopic lithotomy with basket and electrohydraulic lithotripsy is used to remove intrahepatic duct stones, fragments or small stones usually remain in the bile duct that are too small to be captured with a basket. METHODS:An attempt was made to remove stone fragments in 16 patients with intrah...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2001.116881
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Lymphangiohemangioma, also called lymphatic-venous or venolymphatic malformation, is a rare malformation of the lymphatics, with vascular elements. These are low-flow vascular lesions. OBJECTIVE:To evaluate the feasibility and efficacy of endoscopic injection sclerotherapy with doxycycline for low-flow vasc...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2007.06.023
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Surveillance of intestinal metaplasia (IM) of the gastric mucosa should be limited to patients at high risk of gastric cancer. Patients with extensive IM are at increased cancer risk; however, the intragastric extent of IM is usually unknown at the time of the initial diagnosis. OBJECTIVE:To assess the pred...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,多中心研究
doi:10.1016/j.gie.2008.08.041
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett's neoplasia and has advantages over conventional EMR in that it enables en-bloc resection and accurate histopathologic analysis of cancer resection margins. However, its long learning curve and higher adverse ev...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2017.01.027
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Bowel preparation for capsule endoscopy (CE) has not been standardized. OBJECTIVE:This study aimed to compare CE images between patients prepared by simethicone and those prepared by magnesium citrate. DESIGN:Retrospective analysis of case series of our hospital from 2004 to 2007. SETTING:Single center. ...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.04.054
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Despite advances in diagnostic imaging techniques, the differentiation between pancreatic cancer and focal pancreatitis remains difficult. This study evaluated the effectiveness of EUS-guided FNA in the differential diagnosis between pancreatic cancer and focal pancreatitis, with particular reference to dete...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(04)02224-2
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:With recent advances in endoscopy, endoscopic techniques have surpassed esophagectomy in the treatment of dysplastic Barrett's esophagus (BE). OBJECTIVE:To compare the efficacy and safety of complete EMR and radiofrequency ablation (RFA) in the treatment of dysplastic BE. DESIGN:Systematic review of litera...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,评审
doi:10.1016/j.gie.2013.11.030
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Ensuring competence remains a seminal objective of endoscopy training programs, professional organizations, and accreditation bodies; however, no widely accepted measure of endoscopic competence currently exists. OBJECTIVE:By using Delphi methodology, we aimed to develop and establish the content validity o...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2013.10.035
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Over the past decade, ERCP has become the preferred method of treatment for biliary strictures in patients after orthotopic liver transplantation (OLT). Although data strongly support ERCP for treating anastomotic strictures, the little information available for the role of ERCP in the treatment of nonanasto...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.09.057
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2006.12.040
更新日期:2007-07-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.gie.2012.09.014
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Endoscopic ultrasound (EUS)--guided fine-needle aspiration (FNA) is frequently performed for diagnostic evaluation of lesions in or near the gastrointestinal (GI) tract. Little data exist concerning possible infectious complications associated with EUS-guided FNA. This prospective evaluation was undertaken t...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2001.108966
更新日期:2001-02-01 00:00:00
abstract::Although the technique of endoscopic reflectance spectrophotometry has been applied in clinical studies, factors that modify the reproducibility of measurements have not been assessed systematically. To determine the limitations of the technique, measurements were made while endoscopic light intensity, systemic oxygen...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,多中心研究
doi:10.1016/j.gie.2011.03.1125
更新日期:2011-09-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.10.007
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Discrimination between neoplastic and non-neoplastic colorectal polyps is essential for determining appropriate treatment. The mucosal crypt pattern of polyps can be observed with a nonmagnifying colonoscope; however, mucosal crypt patterns are better seen by magnifying colonoscopy, which can also be a nonin...
journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mge.2003.31
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Needle aspiration of the pancreas is performed to differentiate pancreatic malignancy, focal chronic pancreatitis, and metastasis to the pancreas. Biopsies may be directed by using EUS, CT, US, or surgery. This study retrospectively compared the accuracy of EUS-guided, CT/US-guided, and surgical tissue sampl...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(02)70181-8
更新日期:2002-08-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,meta分析
doi:10.1016/j.gie.2018.12.026
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND AND AIMS:Lumen-apposing metal stents (LAMSs) are used to perform necrosectomy in walled-off necrosis (WON). Although necrosectomy is not required for pancreatic pseudocyst (PP), an increasing number of PPs are also being drained with LAMSs in view of their ease of deployment. The aim of the present study was...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2017.11.033
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The efficacy of polyurethane-covered metal expandable stents for treatment of neoplastic distal biliary obstruction was analyzed. METHODS:Twenty-one patients with unresectable malignant tumors involving the mid to distal bile duct who were seen with obstructive jaundice were consecutively enrolled. Eighteen...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2002.121876
更新日期:2002-03-01 00:00:00