Ran-binding protein 3 is associated with human spermatogenesis and male infertility.

abstract：:Seminal oxidative stress plays an important role in male factor infertility (MFI), worldwide. A study was thus undertaken for the first time to establish seminal reactive oxygen species (ROS) as a clinical marker of MFI in a cohort of Sri Lankan males. The nitro blue tetrazolium (NBT) assay for ROS estimation and modi...

journal_title：Andrologia

authors： Amarasekara DS,Wijerathna S,Fernando C,Udagama PV

更新日期：2014-03-01 00:00:00

abstract：:Intermittent hypobaric hypoxia (IHH) induced a decrease in sperm count and oxidative damage in epididymis. We have previously demonstrated that a blueberry-enriched polyphenol extract (BB-4) reduced the adverse effects of oxidative stress in rat testis under hypobaric hypoxia. The aim of this study was to evaluate whe...

journal_title：Andrologia

authors： Zepeda AB,Calaf GM,Figueroa CA,Farías JG

更新日期：2014-09-01 00:00:00

abstract：:In this study, a short stature male with infertility is reported. Semen analysis and serum concentrations of FSH, LH, T and PRL were estimated. Chromosome analysis was performed on lymphocytes obtained from both the male and his parents. Cytogenomic studies were performed by fluorescent in situ hybridisation and the C...

journal_title：Andrologia

authors： Cui YX,Wang WP,Li TF,Li WW,Wu QY,Li N,Zhang C,Yao Q,Hu YA,Xia XY

更新日期：2015-05-01 00:00:00

abstract：:A number of studies indicated a clear decline in semen quality in the past 30-50 years and there is accumulating evidence that this decline might result from exposure to high levels of air pollution. To examine the impact of environment on male reproductive ability, we undertook for the first time a pilot study on sem...

journal_title：Andrologia

authors： Paradisi R,Vanella S,Barzanti R,Cani C,Battaglia C,Seracchioli R,Venturoli S

更新日期：2009-06-01 00:00:00

abstract：:Leptin is a 167-amino acid protein that stimulates gonadotrophin-releasing hormone secretion and exerts indirect effects on the gonads via neuropeptide Y, NPY. Recent research has suggested that leptin may also have an effect on testosterone secretion. To investigate the role of leptin in reproduction, leptin in testi...

journal_title：Andrologia

authors： Glander HJ,Lammert A,Paasch U,Glasow A,Kratzsch J

更新日期：2002-09-01 00:00:00

abstract：:In order to correlate functional and biochemical parameters, frozen bovine sperm samples presenting diverse motility were studied. Specimens collected from four bulls (A, B, C and D) were graded according to motile spermatozoa percentage and vigour, regarding the sample from bull A as highest motility, those from bull...

journal_title：Andrologia

authors： Beorlegui N,Cetica P,Trinchero G,Córdoba M,Beconi M

更新日期：1997-01-01 00:00:00

abstract：:The effect of gossypol--a polycyclic compound isolated from cotton seeds--on the plasminogen activator activity of man and ram acrosomal extracts was explored in vitro. The action of gossypol on the plasminogen activator activity was investigated by a spectrophotometric method using the chromogenic substrate S-2251. G...

journal_title：Andrologia

authors： Taitzoglou IA,Tsantarliotou M,Kouretas D,Kokolis NA

更新日期：1999-12-01 00:00:00

abstract：:A procedure was designed for purification of a human seminal plasma-specific antigen (HSP-antigen) identified by a monoclonal antibody produced in this laboratory (mAb 4E6). Pooled human seminal plasma was fractionated by consecutively applied methods: affinity chromatography on Lentil lectin sepharose, gel chromatogr...

journal_title：Andrologia

authors： Dimitrova D,Kehayov I,Kyurkchiev S

更新日期：1993-09-01 00:00:00

abstract：:Little is known about the biological and clinical significance of bilaterally enlarged testes (bilateral megalotestes or macroorchidism). We have investigated clinical, endocrine and spermatological characteristics of 135 andrological patients with a testicular volume of more than 25 ml bilaterally. 135 patients with ...

journal_title：Andrologia

authors： Meschede D,Behre HM,Nieschlag E

更新日期：1995-07-01 00:00:00

abstract：:The necessity to check up exactly the procedure in vasectomy by the so called - Hamburg Model - is demonstrated by 4 cases. Although these patients were sterilized we could prove fertility on spermiogram, and observed pregnancy in 3 cases. Consequences in matter of law for the surgeon is pointed out. ...

journal_title：Andrologia

authors： Kuhlwein A,Schirren C

更新日期：1981-07-01 00:00:00

abstract：:The scope of this study was to evaluate the accuracy, precision and specificity of the sperm concentration measurements by the Strömberg-Mika Cell Motion Analyser (SM-CMA). Our data show that the instrument generally underscores the sperm concentration and therefore the uncorrected measurements must be corrected by th...

journal_title：Andrologia

authors： Togni G,Gallicciotti G,Coccia P,Piffaretti-Yanez A,Stamm J,Balerna M

更新日期：1995-01-01 00:00:00

abstract：:Cisplatin, a common chemotherapeutic drug, can induce testicular toxicity. Methylene blue, a potent antioxidant, can inhibit the generation of free radicals. This research aimed to study the protective effect of methylene blue against the cisplatin-induced toxicity of the reproductive system in rats. 35 male Wistar ra...

journal_title：Andrologia

authors： Gholami Jourabi F,Yari S,Amiri P,Heidarianpour A,Hashemi H

更新日期：2021-02-01 00:00:00

abstract：:The prime concern of the present work was the analysis of dermatoglyphic patterns in infertile patients presenting with clinically detectable varicocele. In a controlled study conducted on 30 patients and utilizing a slight modification of the original ink method of Cummins and Midlo, the dermatoglyphics on terminal p...

journal_title：Andrologia

authors： Salam EA,Hafiez AR,El Kerdasi Z,Aiad F,Mahmoud KZ

更新日期：1984-03-01 00:00:00

abstract：:A 45-year-old male with azoospermia was presented to us with primary infertility. We found that he had been taking testosterone due to erectile dysfunction. Upon its discontinuation, the normozoospermia was restored. This led to a pregnancy. In men aged 40-50, the diagnostic work up of testosterone deficiency should b...

journal_title：Andrologia

authors： Jan Z,Pfeifer M,Zorn B

更新日期：2012-05-01 00:00:00

abstract：:The mammalian target of rapamycin (TOR) has been implicated in the control of different stressors, growth factors, nutrients and hormones, participating in the control of key cellular functions. Controlling this many pathways poses mTOR signalling as a potential new target in new treatment strategies for multiple canc...

journal_title：Andrologia

authors： Yaba A,Bozkurt ER,Demir N

更新日期：2016-08-01 00:00:00

abstract：:Using a highly sensitive radioimmunoassay (RIA) of estramustine binding protein (EMBP) with the antibody raised against rat-EMBP, the concentration of EMBP in human benign prostatic hypertrophy (BPH) tissue was evaluated. Using mechanical separation procedure, EMBP was found significantly higher in the epithelium (10....

journal_title：Andrologia

authors： Shiina H,Mizutani M,Ishibe T

更新日期：1990-07-01 00:00:00

abstract：:Nerve growth factor (NGF), which is required for the survival and differentiation of the nervous system, has been proved to play important roles in male reproductive physiology. Several studies have focused on the roles of NGF in the testes. However, no study has reported on the mechanism of paracrine and autocrine ac...

journal_title：Andrologia

authors： Jiang YW,Zhao Y,Chen SX,Chen L,Li CJ,Zhou X

更新日期：2018-02-01 00:00:00

abstract：:In 20 autoptically obtained testes from men of various ages, 250-290 testicular lobules per testicle could be recognized by preparation with a stereomicroscope. The most appropriate technique was the fixation of the testes in 10% formol for at least 14 days and a following dehydration in a series of increasing concent...

journal_title：Andrologia

authors： Countouris N,Holstein AF

更新日期：1985-11-01 00:00:00

abstract：:This study aimed to assess seminal mast cells in infertile men associated with varicocele (Vx) pre- and post-surgical repair. Forty-five infertile men associated with Vx were subjected to history taking and clinical examination. In addition, semen parameters and seminal mast cells stained with 1% toluidine blue were e...

journal_title：Andrologia

authors： Mostafa RM,Abol-Magd R,Younis SE,Dessouki OF,Azab M,Mostafa T

更新日期：2017-04-01 00:00:00

abstract：:Several substances can interfere with microtubular function eg. colchicine. Melatonin, a hormone secreted by the pineal gland has similar effects as colchicine on microtubules. In this study melatonin levels were determined in both plasma and seminal plasma of patients with good or impaired motility and forward progre...

journal_title：Andrologia

authors： Bornman MS,Oosthuizen JM,Barnard HC,Schulenburg GW,Boomker D,Reif S

更新日期：1989-09-01 00:00:00

abstract：:5alpha-Dihydrotestosterone (DHT), the most powerful naturally occurring androgen, is commercially available since 1982 as a gel. In view of its considerably higher biopotency (three to six times) than of testosterone, side effects, particularly on the main target organ of androgens, the prostate, are anticipated. In f...

journal_title：Andrologia

authors： Sakhri S,Gooren LJ

更新日期：2007-12-01 00:00:00

abstract：:The authors present the histological features of the testes in 1,609 cases of male sterility. In 485 cases (30.1%), histological changes were found, which did not warrant treatment. The histologic pattern of the testes was normal in only 39% of the cases of azoospermia; and only these patients were qualified for surge...

journal_title：Andrologia

authors： Janczewski Z,Bablok L

更新日期：1978-09-01 00:00:00

abstract：:In fertile men, the majority of epididymal spermatozoa acquire the potential to fertilize (assessed with sperm function assays) on passage into the corpus and cauda regions of the epididymis. Although secretions of the epididymal epithelium are clearly important for sperm maturation and survival, their role in this pr...

journal_title：Andrologia

authors： Moore HD

更新日期：1998-08-01 00:00:00

abstract：:Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is an intractable disease. This study aimed to assess the efficacy of cryotherapy in the therapy of CP/CPPS. One hundred and seventy-two patients with CP/CPPS were randomised to receive cryotherapy or sham cryotherapy. The follow-up assessments were done at we...

journal_title：Andrologia

authors： Peng X,Gao H,Wang J

更新日期：2020-12-24 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR), the key enzyme of the folate metabolic pathway, has been reported to be five times more active in the testicles compared to other organs in adult mice. The aim of this study was to investigate the relationship between MTHFR c.677C>T and c.1298A>C polymorphisms and infertili...

journal_title：Andrologia

authors： Gurkan H,Tozkır H,Göncü E,Ulusal S,Yazar M

更新日期：2015-11-01 00:00:00

abstract：:The aim of the study was to examine possible impacts of paroxetine and agomelatine on the levels of some components that constitute the seminal vesicle fluid. As a second purpose, it was also aimed to examine how possible negative effects induced by paroxetine on seminal vesicle fluid components were affected by kissp...

journal_title：Andrologia

authors： Gulcu Bulmus F,Canpolat S,Sahin Z,Bulmus O,Serhatlioglu I,Kelestimur H

更新日期：2020-05-01 00:00:00

abstract：:Spermatozoa of six men with normozoospermia, oligozoospermia and teratozoospermia were capacitated in vitro in modified Tyrode's medium und evaluated for acrosome reaction using the recently described triple-stain technique. The resulting kinetics illustrate the different capacitation behaviour and ability of spermato...

journal_title：Andrologia

authors： Töpfer-Petersen E,Heissler E,Schill WB

更新日期：1985-05-01 00:00:00

abstract：:Several studies have shown that high oxidative stress levels are associated with varicocele. The GST (glutathione S-transferase) family of genes is critical in the protection of cells from oxidative stress because they utilise as substrates a wide variety of products of oxidative stress. The objective of this study wa...

journal_title：Andrologia

authors： Acar H,Kılınç M,Guven S,Inan Z

更新日期：2012-02-01 00:00:00

abstract：:Fenitrothion (FNT) is a widely used organophosphorus pesticide in agriculture. Quercetin (QR), a plant-derived flavonoid, has a free radical scavenging property. This study investigated the protective effect of QR on FNT-induced testicular toxicity in rats. Twenty-four male rats were divided into four groups. Group I ...

journal_title：Andrologia

authors： Saber TM,Abd El-Aziz RM,Ali HA

更新日期：2016-06-01 00:00:00

abstract：:Chronic prostatitis/chronic pelvic pain syndrome (CP⁄CPPS) is the prostate gland inflammation characterised as genitourinary pain in the pelvic region. The rat experimental autoimmune prostatitis (EAP) was achieved to mimic CP⁄CPPS. The expressions of transient receptor potential vanilloid 1 (TRPV1) in the prostate, b...

journal_title：Andrologia

authors： Zhang J,Yi QT,Gong M,Zhang YQ,Liu D,Zhu RJ

更新日期：2019-09-01 00:00:00