Can Salient Stimuli Enhance Responses in Disorders of Consciousness? A Systematic Review.

abstract：PURPOSE OF REVIEW:This chapter focuses on limb apraxia, a cognitive-motor disorder of learned skilled movement, and the nature of the spatiotemporal errors that disrupt movement sequences. RECENT FINDINGS:A cognitive model that attempts to reconcile conceptual and preparatory aspects of the motor program with perceptu...

journal_title：Current neurology and neuroscience reports

authors： Foundas AL,Duncan ES

更新日期：2019-11-12 00:00:00

abstract：:Mutations in the SNCA gene, which encodes the α-synuclein protein, were the first discovered genetic causes of familial parkinsonism with Lewy pathology. To date, six different SNCA missense mutations as well as multiplications are known to cause parkinsonism. For this review, we performed a literature search to ident...

journal_title：Current neurology and neuroscience reports

authors： Rosborough K,Patel N,Kalia LV

更新日期：2017-04-01 00:00:00

abstract：:The presence of autonomic symptoms can make the diagnosis of headache challenging. While commonly seen with the trigeminal autonomic cephalalgias, autonomic dysfunction can also be present in patients with migraine, or with a variety of secondary headaches. The pathophysiology of cranial autonomic symptoms in headache...

journal_title：Current neurology and neuroscience reports

authors： Ailani J

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Sleep-wake disorders (SWD) are common not only in the general population but also in stroke patients, in whom SWD may be pre-existent or appear "de novo" as a consequence of brain damage. Despite increasing evidence of a negative impact of SWD on cardiocerebrovascular risk, cognitive functions, and qu...

journal_title：Current neurology and neuroscience reports

authors： Duss SB,Brill AK,Bargiotas P,Facchin L,Alexiev F,Manconi M,Bassetti CL

更新日期：2018-09-07 00:00:00

abstract：PURPOSE OF REVIEW:Research has consistently shown that type 2 diabetes (T2D) is associated with increased risk of all-cause dementia. Because one of the most common clinical presentations of early stage dementia is memory impairment, we examined the relationship of T2D with memory function, using the recently published...

journal_title：Current neurology and neuroscience reports

authors： Arvanitakis Z,Tatavarthy M,Bennett DA

更新日期：2020-11-05 00:00:00

abstract：:Degeneration of neuron and axons following injury to cells with which they synapse is termed trans-synaptic degeneration. This phenomenon may be seen in postsynaptic neurons (anterograde) or in presynaptic neurons (retrograde). Retrograde trans-synaptic degeneration (RTSD) of the retinal ganglion cells and retinal ner...

journal_title：Current neurology and neuroscience reports

authors： Dinkin M

更新日期：2017-02-01 00:00:00

abstract：:Over the past few decades, intracranial monitoring technologies focused on treating and preempting secondary injury after traumatic brain injury (TBI) have experienced considerable growth. A physiological measure fundamental to the management of these patients is cerebral blood flow (CBF), which may be determined dire...

journal_title：Current neurology and neuroscience reports

authors： Akbik OS,Carlson AP,Krasberg M,Yonas H

更新日期：2016-08-01 00:00:00

abstract：:There is a close relationship between headache and the visual system. Visual symptoms are prominent features of clinical syndromes such as migraine, cluster headache, and the trigeminal autonomic cephalgias. There are also strong links between headache and the visual system on the basis of genetics, molecular biology,...

journal_title：Current neurology and neuroscience reports

authors： Maxner CE,Moeller JJ

更新日期：2005-09-01 00:00:00

abstract：:Over the last decade, there has been an emerging interest in the link between obstructive sleep apnea (OSA) and ocular health. Though the evidence for OSA playing a role in cerebrovascular disease risk seems clear, the same cannot be said for optic neuropathies. The association between OSA and glaucoma or non-arteriti...

journal_title：Current neurology and neuroscience reports

authors： Fraser CL

更新日期：2014-08-01 00:00:00

abstract：:Seizures represent an important clinical manifestation of inborn errors of metabolism. The presence of myoclonic seizures and very early onset are clues to a metabolic disorder. Specific correlations between age of seizure onset and electroencephalogram patterns with inborn errors of metabolism are discussed. The expl...

journal_title：Current neurology and neuroscience reports

authors： Pearl PL,Bennett HD,Khademian Z

更新日期：2005-03-01 00:00:00

abstract：:Ependymomas are rare primary central nervous system tumors in adults. They occur most commonly in the spinal cord, where histopathologic evaluation is critical to differentiate the grade I myxopapillary ependymoma from the grade II ependymoma or grade III anaplastic ependymoma. Brain ependymomas are either grade II or...

journal_title：Current neurology and neuroscience reports

authors： Gilbert MR,Ruda R,Soffietti R

更新日期：2010-05-01 00:00:00

abstract：:Parkinson's disease (PD) is a movement disorder associated with the degeneration of nigral dopaminergic (DA) neurons. One of the greatest obstacles for PD research is the lack of patient-specific nigral DA neurons for mechanistic studies and drug discovery. The advent of induced pluripotent stem cells (iPSCs) has over...

journal_title：Current neurology and neuroscience reports

authors： Pu J,Jiang H,Zhang B,Feng J

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Abnormal accumulation of tau protein is the main hallmark of tauopathies and is closely associated with neurodegeneration and cognitive impairment, whereas the advance in PET imaging provides a non-invasive detection of tau inclusions in the brain. In this review, we discuss the potential of PET imagi...

journal_title：Current neurology and neuroscience reports

authors： Wang YT,Edison P

更新日期：2019-06-06 00:00:00

abstract：:Microglial activation is a key aspect of the neuroinflammatory process in neurodegenerative disorders including idiopathic and atypical parkinsonian disorders. Using positron emission tomography, it has become possible to image this phenomenon in vivo and over the last years patterns of microglia activation correspond...

journal_title：Current neurology and neuroscience reports

authors： Gerhard A

更新日期：2013-12-01 00:00:00

abstract：:Prospective studies conducted during the last decade have shown that the majority of patients with Parkinson's disease (PD) develop dementia. In addition, using a variety of definitions and methods, more recent research suggests that approximately a quarter of PD patients without dementia have mild cognitive impairmen...

journal_title：Current neurology and neuroscience reports

authors： Aarsland D,Brønnick K,Fladby T

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Elevated cholesterol is an established risk factor for ischemic stroke. The value of statins for stroke prevention has been clear for more than a decade. RECENT FINDINGS:However, the use of new medication combinations such as ezetimibe or proprotein convertase subtilisin-kexin type 9 inhibitors plus ...

journal_title：Current neurology and neuroscience reports

authors： Aradine E,Hou Y,Cronin CA,Chaturvedi S

更新日期：2020-06-22 00:00:00

abstract：:Although the co-occurrence of myelitis and optic neuritis that characterizes neuromyelitis optica (NMO) was recognized over a century ago, distinguishing NMO from multiple sclerosis relied solely on clinical criteria until recently. The identification of a biomarker that has high specificity for NMO is clinically usef...

journal_title：Current neurology and neuroscience reports

authors： Cree B

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic REM sleep behavior disorder (iRBD) is one of the most significant prodromal manifestations of synucleinopathies. Different predictive biomarkers for iRBD conversion have been investigated, but scarce data are present in literature about the predictive role of cerebrospinal fluid (CSF) bioma...

journal_title：Current neurology and neuroscience reports

authors： Liguori C,Paoletti FP,Placidi F,Ruffini R,Sancesario GM,Eusebi P,Mercuri NB,Parnetti L

更新日期：2019-01-14 00:00:00

abstract：:Parkinson's disease, a common neurodegenerative disorder, results in significant morbidity 10 to 15 years after disease onset and increased mortality. Levodopa is the mainstay of therapy and provides benefit for the duration of the illness. However, within 5 years, up to 50% of individuals develop fluctuations, includ...

journal_title：Current neurology and neuroscience reports

authors： Suchowersky O

更新日期：2002-07-01 00:00:00

abstract：:Transportation issues in industrialized nations play an important role in the lives of most citizens. The acts of flying and driving, especially in the United States, intersect with many peoples' lives on almost a daily basis. Although some larger cities have modern and efficient public transportation systems, many do...

journal_title：Current neurology and neuroscience reports

authors： Drazkowski JF

更新日期：2007-07-01 00:00:00

abstract：:New strategies to lower the risk of stroke among high-risk persons are being developed. Therapies such as cholesterol-lowering medications and newer antihypertensive agents appear to complement traditional antithrombotic drugs and surgical procedures. Of particular interest is the use of the newer angiotensin-converti...

journal_title：Current neurology and neuroscience reports

authors： Adams HP

更新日期：2003-01-01 00:00:00

abstract：:Syringobulbia is an uncommon condition, usually a late complication of syringomyelia. It has predilection for the dorsolateral region of the medulla leading to damage to vestibular nuclei and their connections, as well as to the descending sympathetic fibers. Oscillopsia, nystagmus, and Horner syndrome are frequent ma...

journal_title：Current neurology and neuroscience reports

authors： Nogués M,López L,Meli F

更新日期：2010-11-01 00:00:00

abstract：:We present a discussion of recent relevant publications in pediatric epilepsy surgery. In 1998, the Commission on Neurosurgery of the International League Against Epilepsy formed the Subcommission for Pediatric Epilepsy Surgery. Their proposed recommendations are included here. We also discuss updates on identificatio...

journal_title：Current neurology and neuroscience reports

authors： Depositario-Cabacar DT,Riviello JJ,Takeoka M

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study was to briefly discuss chemotherapy-induced peripheral neuropathy (CIPN) and detail the most important and most recent chemotherapeutic agents implicated. This review will examine neuropathy mechanisms, risk factors, and clinical patterns; novel and prospective drugs with sim...

journal_title：Current neurology and neuroscience reports

authors： Cioroiu C,Weimer LH

更新日期：2017-06-01 00:00:00

abstract：:Attention deficit/hyperactivity disorder (AD/HD) can cause significant impairment in psychosocial and scholastic achievement. AD/HD should be appropriately managed even if patients have comorbid epilepsy. The diagnosis and treatment of AD/HD in patients with epilepsy presents several challenges. Differentiating indepe...

journal_title：Current neurology and neuroscience reports

authors： Brown MG,Becker DA,Pollard JR,Anderson CT

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with Parkinson's disease (PD) often display gastrointestinal and genitourinary autonomic symptoms years or even decades prior to diagnosis. These symptoms are thought to be caused in part by pathological α-synuclein inclusions in the peripheral autonomic and enteric nervous systems. It has be...

journal_title：Current neurology and neuroscience reports

authors： Knudsen K,Borghammer P

更新日期：2018-09-19 00:00:00

abstract：:Cortical malformations associated with defects in neuronal migration result in severe developmental consequences including intractable epilepsy and intellectual disability. Genetic causes of migration defects have been identified with the advent and widespread use of high-resolution MRI and genetic techniques. Thus, t...

journal_title：Current neurology and neuroscience reports

authors： Liu JS

更新日期：2011-04-01 00:00:00

abstract：:There is an increasing awareness that impulse control disorders (ICDs), including pathologic gambling and compulsive sexual behavior, can occur as a complication of Parkinson's disease (PD). Anecdotal experience and case reporting have suggested an association between ICDs in PD and the use of dopamine agonists. Lacki...

journal_title：Current neurology and neuroscience reports

authors： Weintraub D,Potenza MN

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Parkinson's disease (PD) is a complex neurodegenerative disorder, the aetiology of which is still largely unknown. Overwhelming evidence indicates that mitochondrial dysfunction is a central factor in PD pathophysiology. Here we review recent developments around mitochondrial dysfunction in familial a...

journal_title：Current neurology and neuroscience reports

authors： Park JS,Davis RL,Sue CM

更新日期：2018-04-03 00:00:00

abstract：:Migraine is a common disabling neurological disorder resulting from excessive cortical excitation and trigeminovascular afferent sensitization. In addition to aberrant neuronal processing, migraineurs are also at significant risk of vascular disease. Consequently, the impact of migraine extends well beyond the ictal h...

journal_title：Current neurology and neuroscience reports

authors： Harriott AM,Barrett KM

更新日期：2015-03-01 00:00:00